Privacy Challenges of Genomic Big Data
With the rapid advancement of high-throughput DNA sequencing technologies, genomics has become a big data discipline where large-scale genetic information of human individuals can be obtained efficiently with low cost. However, such massive amount of personal genomic data creates tremendous challeng...
        Saved in:
      
    
          | Published in | Advances in experimental medicine and biology Vol. 1028; pp. 139 - 148 | 
|---|---|
| Main Authors | , | 
| Format | Book Chapter Journal Article | 
| Language | English | 
| Published | 
        Singapore
          Springer Singapore
    
        01.01.2017
     | 
| Series | Advances in Experimental Medicine and Biology | 
| Subjects | |
| Online Access | Get full text | 
| ISBN | 9789811060403 9811060401  | 
| ISSN | 0065-2598 2214-8019  | 
| DOI | 10.1007/978-981-10-6041-0_8 | 
Cover
| Abstract | With the rapid advancement of high-throughput DNA sequencing technologies, genomics has become a big data discipline where large-scale genetic information of human individuals can be obtained efficiently with low cost. However, such massive amount of personal genomic data creates tremendous challenge for privacy, especially given the emergence of direct-to-consumer (DTC) industry that provides genetic testing services. Here we review the recent development in genomic big data and its implications on privacy. We also discuss the current dilemmas and future challenges of genomic privacy. | 
    
|---|---|
| AbstractList | With the rapid advancement of high-throughput DNA sequencing technologies, genomics has become a big data discipline where large-scale genetic information of human individuals can be obtained efficiently with low cost. However, such massive amount of personal genomic data creates tremendous challenge for privacy, especially given the emergence of direct-to-consumer (DTC) industry that provides genetic testing services. Here we review the recent development in genomic big data and its implications on privacy. We also discuss the current dilemmas and future challenges of genomic privacy. | 
    
| Author | Shen, Hong Ma, Jian  | 
    
| Author_xml | – sequence: 1 givenname: Hong surname: Shen fullname: Shen, Hong email: hongs@andrew.cmu.edu organization: Department of Engineering and Public Policy, Carnegie Mellon University, Pittsburgh, USA – sequence: 2 givenname: Jian surname: Ma fullname: Ma, Jian email: jianma@cs.cmu.edu organization: Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, USA  | 
    
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29058220$$D View this record in MEDLINE/PubMed | 
    
| BookMark | eNpVkMtOwzAQRQ0U0bT0C5BQVuwMM3ac2EsaoCBVgkX3lhPbJZBHlRSk_j2OCgtWo_vQ6OrMyKTtWkfIFcItAmR3KpNUSaQINIUEKWh5QhbBDSbCaMEpiRjDhEpAdfYvAz4hEUAqKBNKTslsGD4ARMZSvCBTpkBIxiAiN2999W3KQ5y_m7p27dYNcefjlWu7pirjZbWNH8zeXJJzb-rBLX7vnGyeHjf5M12_rl7y-zXdMcH3VHKhWOJMYnxaCJ8pjlAk0nMohc14URgwktsyQ4nOWgHeKSjRKjBMJIbPyfXx7e6raJzVu75qTH_Qf3tDAY-FIURhbK-LrvscNIIemelAQAcEox4B6cCM_wCkIlcF | 
    
| ContentType | Book Chapter Journal Article  | 
    
| Copyright | Springer Nature Singapore Pte Ltd. 2017 | 
    
| Copyright_xml | – notice: Springer Nature Singapore Pte Ltd. 2017 | 
    
| DBID | CGR CUY CVF ECM EIF NPM  | 
    
| DOI | 10.1007/978-981-10-6041-0_8 | 
    
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed  | 
    
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid)  | 
    
| DatabaseTitleList | MEDLINE | 
    
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database  | 
    
| DeliveryMethod | fulltext_linktorsrc | 
    
| Discipline | Medicine Biology  | 
    
| EISBN | 9789811060410 981106041X  | 
    
| EISSN | 2214-8019 | 
    
| Editor | Shen, Bairong | 
    
| Editor_xml | – sequence: 1 givenname: Bairong surname: Shen fullname: Shen, Bairong email: bairong.shen@suda.edu.cn  | 
    
| EndPage | 148 | 
    
| ExternalDocumentID | 29058220 | 
    
| Genre | Journal Article Review  | 
    
| GroupedDBID | --- 23M 5GY 5RE ACGFS AENEX ALMA_UNASSIGNED_HOLDINGS F5P L7B P2P RSU ~KM 53G CGR CUY CVF ECM EIF NPM ZGI  | 
    
| ID | FETCH-LOGICAL-p253t-835924ea4af6b5f79310b48f30c5d73bba0a83dc7181edd50fe90c1d90a254a3 | 
    
| ISBN | 9789811060403 9811060401  | 
    
| ISSN | 0065-2598 | 
    
| IngestDate | Wed Feb 19 02:42:22 EST 2025 Tue Jul 29 19:55:04 EDT 2025  | 
    
| IsPeerReviewed | true | 
    
| IsScholarly | true | 
    
| Keywords | Personal genomic data Computational methods Genomic privacy  | 
    
| Language | English | 
    
| LinkModel | OpenURL | 
    
| MergedId | FETCHMERGED-LOGICAL-p253t-835924ea4af6b5f79310b48f30c5d73bba0a83dc7181edd50fe90c1d90a254a3 | 
    
| PMID | 29058220 | 
    
| PageCount | 10 | 
    
| ParticipantIDs | pubmed_primary_29058220 springer_books_10_1007_978_981_10_6041_0_8  | 
    
| PublicationCentury | 2000 | 
    
| PublicationDate | 2017-01-01 | 
    
| PublicationDateYYYYMMDD | 2017-01-01 | 
    
| PublicationDate_xml | – month: 01 year: 2017 text: 2017-01-01 day: 01  | 
    
| PublicationDecade | 2010 | 
    
| PublicationPlace | Singapore | 
    
| PublicationPlace_xml | – name: Singapore – name: United States  | 
    
| PublicationSeriesTitle | Advances in Experimental Medicine and Biology | 
    
| PublicationSeriesTitleAlternate | Adv Exp Med Biol | 
    
| PublicationTitle | Advances in experimental medicine and biology | 
    
| PublicationTitleAlternate | Adv Exp Med Biol | 
    
| PublicationYear | 2017 | 
    
| Publisher | Springer Singapore | 
    
| Publisher_xml | – name: Springer Singapore | 
    
| RelatedPersons | REZAEI, NIMA LAJTHA, ABEL PAOLETTI, RODOLFO COHEN, IRUN R. LAMBRIS, JOHN D.  | 
    
| RelatedPersons_xml | – sequence: 1 givenname: IRUN R. surname: COHEN fullname: COHEN, IRUN R. organization: DEPT CELL BIO, The Weizmann Institute of Science, Rehovot, Israel – sequence: 2 givenname: ABEL surname: LAJTHA fullname: LAJTHA, ABEL organization: N.S.Kline Institute for Psychiatric Rrch, ORANGEBURG, USA – sequence: 3 givenname: JOHN D. surname: LAMBRIS fullname: LAMBRIS, JOHN D. organization: Pathology& Lab Med, 401 Stellar Chance, University of Pennsylvania, PHILADELPHIA, USA – sequence: 4 givenname: RODOLFO surname: PAOLETTI fullname: PAOLETTI, RODOLFO organization: University of Milan, Milan, Italy – sequence: 5 givenname: NIMA surname: REZAEI fullname: REZAEI, NIMA organization: Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran  | 
    
| SSID | ssj0057261 ssj0001929776  | 
    
| Score | 2.0761821 | 
    
| SecondaryResourceType | review_article | 
    
| Snippet | With the rapid advancement of high-throughput DNA sequencing technologies, genomics has become a big data discipline where large-scale genetic information of... | 
    
| SourceID | pubmed springer  | 
    
| SourceType | Index Database Publisher  | 
    
| StartPage | 139 | 
    
| SubjectTerms | Computational methods Genomic privacy Genomics Humans Patient Participation Personal genomic data Privacy  | 
    
| Title | Privacy Challenges of Genomic Big Data | 
    
| URI | http://link.springer.com/10.1007/978-981-10-6041-0_8 https://www.ncbi.nlm.nih.gov/pubmed/29058220  | 
    
| Volume | 1028 | 
    
| hasFullText | 1 | 
    
| inHoldings | 1 | 
    
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1JT9wwFLY6U4EQl5Zu0wXlUPXQKihO4iwHDhRNO0IdhMRQcYvs2EZcZhAEDvz6fl6yMOUCl2gSjWLnffF7n1_eQshXzaTpti3DjAsVpkon0IMxDWUm8hwGRZbaZCPPj7PZWXp0zs77Lo42u6QRe_X9o3klz0EV14CryZJ9ArLdTXEBv4EvjkAYxzXy-9DNOqhTaCO3jPP75-UFIGz4IwEtpz4DY7byZsp6oC1-3cvh7nlyfXln-r8fti1WbKDHb2Vzl7shnCYyFZJv9g9cDIGNqp0OuwXM_Ud7P7nee-9dDDRfczG0LsYfp6ZLN7YF6sEmtCxAITIog2SoaE3wHHMNpveUvRbHNDUGsRzoS-oqGXnTS13Rzf-0eh_IgbGM4cBomGFVjMgoL6DdXh5Mj_787X1r4Hy5oVnOIrM8zlznRD8pV3ipnzd2690J7UpTuerDayMOiMral3NLSBavyLZJUglM9ggWxmvyQi13yIYX8w7ZbKX_hnzzmAY9psFKBx7TAJgGBtO3ZPFrujichb45RngVs6QJwZyxdVY85ToTTEPN0kikhU6imsk8EYJHvEhkDe5BlZQs0qqMairLiMcs5ck7Ml6uluoDCRRIqEwLlesa67bOyoxD62OZ1VwnhaAT8t49cnXlCqBUcRkxEMtoQr63MqjMOrip2iLYkFwFyZlzI7kKkvv4lD9_Ilv9i_iZjJvrW_UF7K8Rux7sXTI6Ppn_A11BS94 | 
    
| linkProvider | Library Specific Holdings | 
    
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.title=Healthcare+and+Big+Data+Management&rft.au=Shen%2C+Hong&rft.au=Ma%2C+Jian&rft.atitle=Privacy+Challenges+of+Genomic+Big+Data&rft.series=Advances+in+Experimental+Medicine+and+Biology&rft.date=2017-01-01&rft.pub=Springer+Singapore&rft.isbn=9789811060403&rft.issn=0065-2598&rft.eissn=2214-8019&rft.spage=139&rft.epage=148&rft_id=info:doi/10.1007%2F978-981-10-6041-0_8 | 
    
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0065-2598&client=summon | 
    
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0065-2598&client=summon | 
    
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0065-2598&client=summon |