Deep Photoacoustic/Luminescence/Magnetic Resonance Multimodal Imaging in Living Subjects Using High‐Efficiency Upconversion Nanocomposites
A gadolinium‐doped multi‐shell upconversion nanoparticle under 800 nm excitation is synthesized with a 10‐fold fluorescence‐intensity enhancement over that under 980 nm. The nanoformulations exhibit excellent photoacoustic/luminescence/magnetic resonance tri‐modal imaging capabilities, enabling visu...
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| Published in | Advanced materials (Weinheim) Vol. 28; no. 30; pp. 6411 - 6419 |
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| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Germany
01.08.2016
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0935-9648 1521-4095 1521-4095 |
| DOI | 10.1002/adma.201506460 |
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| Abstract | A gadolinium‐doped multi‐shell upconversion nanoparticle under 800 nm excitation is synthesized with a 10‐fold fluorescence‐intensity enhancement over that under 980 nm. The nanoformulations exhibit excellent photoacoustic/luminescence/magnetic resonance tri‐modal imaging capabilities, enabling visualization of tumor morphology and microvessel distribution at a new imaging depth. |
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| AbstractList | A gadolinium-doped multi-shell upconversion nanoparticle under 800 nm excitation is synthesized with a 10-fold fluorescence-intensity enhancement over that under 980 nm. The nanoformulations exhibit excellent photoacoustic/luminescence/magnetic resonance tri-modal imaging capabilities, enabling visualization of tumor morphology and microvessel distribution at a new imaging depth. A gadolinium-doped multi-shell upconversion nanoparticle under 800 nm excitation is synthesized with a 10-fold fluorescence-intensity enhancement over that under 980 nm. The nanoformulations exhibit excellent photoacoustic/luminescence/magnetic resonance tri-modal imaging capabilities, enabling visualization of tumor morphology and microvessel distribution at a new imaging depth.A gadolinium-doped multi-shell upconversion nanoparticle under 800 nm excitation is synthesized with a 10-fold fluorescence-intensity enhancement over that under 980 nm. The nanoformulations exhibit excellent photoacoustic/luminescence/magnetic resonance tri-modal imaging capabilities, enabling visualization of tumor morphology and microvessel distribution at a new imaging depth. |
| Author | Zhao, Qingliang Lv, Jing Liu, Yu Ma, Lingceng Nie, Liming Kang, Ning Zhou, Zijian Ren, Lei Chen, Zhong |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27185066$$D View this record in MEDLINE/PubMed |
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| Copyright | 2016 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
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| Keywords | deep imaging multi-shell structure high-efficiency upconversion luminescence magnetic resonance imaging photoacoustic (PA) imaging |
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| Snippet | A gadolinium‐doped multi‐shell upconversion nanoparticle under 800 nm excitation is synthesized with a 10‐fold fluorescence‐intensity enhancement over that... A gadolinium-doped multi-shell upconversion nanoparticle under 800 nm excitation is synthesized with a 10-fold fluorescence-intensity enhancement over that... |
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| SubjectTerms | deep imaging high‐efficiency upconversion luminescence Imaging Luminescence Magnetic resonance magnetic resonance imaging multi‐shell structure Nanocomposites Nanostructure photoacoustic (PA) imaging Tumors Upconversion Visualization |
| Title | Deep Photoacoustic/Luminescence/Magnetic Resonance Multimodal Imaging in Living Subjects Using High‐Efficiency Upconversion Nanocomposites |
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