The fatty acid oxidation product 15‐A3t‐Isoprostane is a potent inhibitor of NFκB transcription and macrophage transformation - Brooks, Joshua D.; Musiek, Erik S.; Koestner, Tyler R.; Stankowski, Jeannette N.; Howard, Jocelyn R.; Brunoldi, Enrico M.; Porta, Alessio; Zanoni, Giuseppe; Vidari, Giovanni; Morrow, Jason D.; Milne, Ginger L.; McLaughlin, BethAnn (Journal of neurochemistry, 2011)
Keywords: Alzheimer's disease; Animals; Cell Line; cytoprotection; eicosapentaenoic acid; Fatty Acids - metabolism; Fatty Acids - physiology; inflammation; Isoprostanes - chemistry; Isoprostanes - pharmacology; Isoprostanes - physiology; Macrophage Activation - drug effects; Macrophage Activation - physiology; Macrophages - drug effects; Macrophages - metabolism; Mice; NF-kappa B - antagonists & inhibitors; NF-kappa B - genetics; NF-kappa B - metabolism; Oxidation-Reduction; oxidative stress; Oxidative Stress - drug effects; Oxidative Stress - physiology; Transcription, Genetic - drug effects; Transcription, Genetic - physiology