Anti-PrP Mab 6D11 suppresses PrP(Sc) replication in prion infected myeloid precursor line FDC-P1/22L and in the lymphoreticular system in vivo - Sadowski, Martin J; Pankiewicz, Joanna; Prelli, Frances; Scholtzova, Henrieta; Spinner, Daryl S; Kascsak, Regina B; Kascsak, Richard J; Wisniewski, Thomas (Neurobiology of disease, 2009)
Keywords: Animals; Antibodies, Monoclonal - pharmacology; Blood-Brain Barrier - drug effects; Blood-Brain Barrier - immunology; Blood-Brain Barrier - metabolism; Brain - drug effects; Brain - immunology; Brain - metabolism; Cell Line; Down-Regulation - drug effects; Down-Regulation - immunology; Female; Humans; Immunization, Passive - methods; Lymphatic System - drug effects; Lymphatic System - immunology; Lymphatic System - metabolism; Mice; Myeloid Cells - drug effects; Myeloid Cells - immunology; Myeloid Cells - metabolism; Myeloid Progenitor Cells - drug effects; Myeloid Progenitor Cells - immunology; Myeloid Progenitor Cells - metabolism; Prion Diseases - drug therapy; Prion Diseases - immunology; Prion Diseases - metabolism; Protein Conformation - drug effects; PrPSc Proteins - antagonists & inhibitors; PrPSc Proteins - biosynthesis; Scrapie - drug therapy; Scrapie - immunology; Scrapie - metabolism; Treatment Outcome