钠牛磺胆酸共转运多肽在肝胆疾病中的研究进展
钠牛磺胆酸共转运多肽(NTCP)既是胆汁酸吸收入肝的重要转运体，又是HBV、HDV的功能性受体; 其结构、功能、基因特点、表达调控机制等已得到广泛研究; 且NTCP与慢性病毒性肝炎、非酒精性脂肪性肝病、肝纤维化、原发性胆汁性胆管炎、肝细胞癌相关，本文系统阐述了NTCP在各种肝胆疾病中的作用，为相关疾病的诊断及治疗提供新方向。...
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| Published in | Linchuang gandanbing zazhi Vol. 38; no. 5; pp. 1179 - 1182 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | Chinese |
| Published |
Changchun
Journal of Clinical Hepatology
01.05.2022
中国人民解放军总医院第五医学中心肝脏肿瘤诊疗与研究中心,北京100039%贵州医科大学附属医院肝胆外科,贵阳550004%中国人民解放军总医院第五医学中心肝脏肿瘤诊疗与研究中心,北京100039 贵州医科大学附属医院肝胆外科,贵阳550004 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1001-5256 2097-3497 |
| DOI | 10.3969/j.issn.1001-5256.2022.05.043 |
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| Abstract | 钠牛磺胆酸共转运多肽(NTCP)既是胆汁酸吸收入肝的重要转运体，又是HBV、HDV的功能性受体; 其结构、功能、基因特点、表达调控机制等已得到广泛研究; 且NTCP与慢性病毒性肝炎、非酒精性脂肪性肝病、肝纤维化、原发性胆汁性胆管炎、肝细胞癌相关，本文系统阐述了NTCP在各种肝胆疾病中的作用，为相关疾病的诊断及治疗提供新方向。 |
|---|---|
| AbstractList | 钠牛磺胆酸共转运多肽(NTCP)既是胆汁酸吸收入肝的重要转运体，又是HBV、HDV的功能性受体; 其结构、功能、基因特点、表达调控机制等已得到广泛研究; 且NTCP与慢性病毒性肝炎、非酒精性脂肪性肝病、肝纤维化、原发性胆汁性胆管炎、肝细胞癌相关，本文系统阐述了NTCP在各种肝胆疾病中的作用，为相关疾病的诊断及治疗提供新方向。 钠牛磺胆酸共转运多肽(NTCP)既是胆汁酸吸收入肝的重要转运体,又是HBV、HDV的功能性受体;其结构、功能、基因特点、表达调控机制等已得到广泛研究;且NTCP与慢性病毒性肝炎、非酒精性脂肪性肝病、肝纤维化、原发性胆汁性胆管炎、肝细胞癌相关,本文系统阐述了NTCP在各种肝胆疾病中的作用,为相关疾病的诊断及治疗提供新方向. |
| Author | 陆荫英 贾晓东 高小强 左石 |
| AuthorAffiliation | 贵州医科大学附属医院肝胆外科,贵阳550004;中国人民解放军总医院第五医学中心肝脏肿瘤诊疗与研究中心,北京100039%贵州医科大学附属医院肝胆外科,贵阳550004%中国人民解放军总医院第五医学中心肝脏肿瘤诊疗与研究中心,北京100039 |
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| Keywords | 非酒精性脂肪性肝病 肝炎,病毒性,人 肝硬化,胆汁性 肝硬化 癌,肝细胞 钠牛磺胆酸共转运多肽 |
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| Snippet | 钠牛磺胆酸共转运多肽(NTCP)既是胆汁酸吸收入肝的重要转运体，又是HBV、HDV的功能性受体; 其结构、功能、基因特点、表达调控机制等已得到广泛研究; 且NTCP与慢性病毒性肝炎、非... 钠牛磺胆酸共转运多肽(NTCP)既是胆汁酸吸收入肝的重要转运体,又是HBV、HDV的功能性受体;其结构、功能、基因特点、表达调控机制等已得到广泛研究;且NTCP与慢性病毒性肝炎、非酒... |
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