합성의약품으로 호전되지 않은 소화기 증상 환자(KCD K-코드)에 대한 반하사심탕 제제 병용의 효과 : 후향적 차트 분석

• Published in: 대한한방내과학회지 Vol. 42; no. 6; pp. 1349 - 1355
• Main Authors: 김철현, 김광호, 이영웅, 강선이, 강건희, Kim, Cheol-hyun, Kim, Kwangho, Lee, Young-ung, Kang, Sunny, Kang, Geonhui
• Format: Journal Article
• Language: Korean
• Published: 대한한방내과학회 01.12.2021
• Subjects: 한의학; Banha-sasim-tang; Nepean Dyspepsia Index-Korean version (NDI-K); retrospective chart review; herbal medicine formulation; gastrointestinal symptoms
• ISSN: 1226-9174
• DOI: 10.22246/jikm.2021.42.6.1349

Objectives: The aim of this study was to evaluate the effectiveness of additional administration of Banha-sasim-tang formulation to patients with gastrointestinal symptoms that did not improve with Western medicines. Methods: The patients who met the inclusion and exclusion criteria were analyzed retrospectively. A paired t-test was performed on the Nepean Dyspepsia Index-Korean version (NDI-K) scores before and after administering the Banha-sasim-tang formulation. Results: A total of 27 subjects were included. The mean duration of taking the Banha-sasim-tang formulation was 15.6±3.1 days. The most commonly used Western medicine before taking the Banha-sasim-tang formulation was rebamipide. The means of the NDI-K score were 57.4±21.8 before administering Banha-sasim-tang formulation and 34.9±16.5 after administration, and the difference was statistically significant (p<0.0001). No serious side effects were encountered while taking the Banha-sasim-tang formulation. Conclusions: For patients whose gastrointestinal symptoms do not improve with Western medicines, additional administration of Banha-sasim-tang formulation may be an option. However, as this study is a retrospective chart review, prospective, large-scale, double-blind studies are needed in the future.