비소세포폐암 환자에서 발생한 지속성 딸꾹질 1예

• Published in: Tuberculosis and respiratory diseases Vol. 64; no. 1; pp. 39 - 43
• Main Authors: 박혜성, 심윤수, 임소연, 조정연, 권성신, 노선희, 김유리, 천은미, 이진화, 류연주, 송동은, 문진욱, Park, Hye Sung, Sim, Yun Su, Lim, So Yeon, Jo, Jung Youn, Kwon, Sung Shin, Roh, Sun Hee, Kim, Yoo Ri, Chun, Eun Mi, Lee, Jin Hwa, Ryu, Yon Ju, Song, Dong Eun, Moon, Jin Wook
• Format: Journal Article
• Language: Korean
• Published: 대한결핵및호흡기학회 2008
• Subjects: 내과학; Singultus; Chlorpromazine; Lung cancer; Hiccup
• ISSN: 1738-3536; 2005-6184

A hiccup is caused by involuntary, intermittent, and spasmodic contractions of the diaphragm and intercostal muscles. It starts with a sudden inspiration and ends with an abrupt closure of the glottis. Even though a hiccup is thought to develop through the hiccup reflex arc, its exact pathophysiology is still unclear. The etiologies include gastrointestinal disorders, respiratory abnormalities, psychogenic factors, toxic-metabolic disorders, central nervous system dysfunctions and irritation of the vagus and phrenic nerves. Most benign hiccups can be controlled by traditional empirical therapy such as breath holding and swallowing water. However, though rare, a persistent hiccup longer than 48 hours can lead to significant adverse effects including malnutrition, dehydration, insomnia, electrolyte imbalance, and cardiac arrhythmia. An intractable hiccup can sometimes even cause death. We herein describe a patient with non-small cell lung cancer who was severely distressed by a persistent hiccup. 저자 등은 종격동 림프절 비대를 동반한 비소세포폐암환자에서 발생한 지속성 딸꾹질을 경험하였기에 이에 대한 임상적 특성과 치료에 관한 문헌 고찰과 함께 보고하는 바이다.