Auditory Brainstem Responses and the Diagnosis of Acoustic and C-P angle Tumours

In 25 patients with confirmed acoustic and cerebellopontine angle tumours seen in our clinic from 1979 to 1983, the auditory brainstem responses (ABR) were evaluated in relation to the ABR patterns stimulated on affected and non affected ears by means of click sounds. The results are as follows; 1)...

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Published inOTOLOGIA FUKUOKA Vol. 30; no. 4Supplement2; pp. 808 - 817
Main Authors SHIRAISHI, Kimio, KATO, Toshihiko, KIMURA, Ken-ichi, SODA, Toyoji
Format Journal Article
LanguageJapanese
Published JIBI TO RINSHO KAI 20.10.1984
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ISSN0447-7227
2185-1034
DOI10.11334/jibi1954.30.4Supplement2_808

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Abstract In 25 patients with confirmed acoustic and cerebellopontine angle tumours seen in our clinic from 1979 to 1983, the auditory brainstem responses (ABR) were evaluated in relation to the ABR patterns stimulated on affected and non affected ears by means of click sounds. The results are as follows; 1) The ABR patterns obtained from the affected ear stimulation could be separated into 3 types. Type A showed a prolongation of the I-II inter peak latency (IPL) or I-V IPL. Type B showed the presence of wave I only or waves I and II. Type C showed no response. 2) The ABR patterns obtained from non tumour ear stimulation could be separated into 3 types. Type 1 showed the normal range of I-V IPL. Type 2 showed a prolongation of III-V IPL. Type 3, the wave V was still poorly defined or wave V was absent. The abnormalities were observed in 67% of the subjects. 3) The size of tumours in types 2 and 3 were larger than 3cm. as measured on the CT scans. The different ABR components in the affected ear, as compared with findings in the non affected ear provide pertinent information which leads to an early diagnosis of acoustic and cerebellopontine angle tumours. The relationship between the size and location of tumour can also be defined.
AbstractList In 25 patients with confirmed acoustic and cerebellopontine angle tumours seen in our clinic from 1979 to 1983, the auditory brainstem responses (ABR) were evaluated in relation to the ABR patterns stimulated on affected and non affected ears by means of click sounds. The results are as follows; 1) The ABR patterns obtained from the affected ear stimulation could be separated into 3 types. Type A showed a prolongation of the I-II inter peak latency (IPL) or I-V IPL. Type B showed the presence of wave I only or waves I and II. Type C showed no response. 2) The ABR patterns obtained from non tumour ear stimulation could be separated into 3 types. Type 1 showed the normal range of I-V IPL. Type 2 showed a prolongation of III-V IPL. Type 3, the wave V was still poorly defined or wave V was absent. The abnormalities were observed in 67% of the subjects. 3) The size of tumours in types 2 and 3 were larger than 3cm. as measured on the CT scans. The different ABR components in the affected ear, as compared with findings in the non affected ear provide pertinent information which leads to an early diagnosis of acoustic and cerebellopontine angle tumours. The relationship between the size and location of tumour can also be defined.
Author KATO, Toshihiko
SODA, Toyoji
KIMURA, Ken-ichi
SHIRAISHI, Kimio
Author_FL 加藤 寿彦
曽田 豊二
白石 君男
木村 謙一
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  fullname: SHIRAISHI, Kimio
  organization: Department of Otorhinolaryngology, School of Medicine, Fukuoka University
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  fullname: KIMURA, Ken-ichi
  organization: Department of Otorhinolaryngology, School of Medicine, Fukuoka University
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  fullname: SODA, Toyoji
  organization: Department of Otorhinolaryngology, School of Medicine, Fukuoka University
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References 3) BUCHWALD J. S and HUANG C M: Far-field acoustic response: Origins in the cat. Science 189: 382-384, 1975.
14) 柏木譲治他: 小脳橋角部障害へのBSRの応用. 日耳鼻81: 578-586, 1978.
17) 神崎仁他: 聴神経腫瘍の他覚的聴覚検査診断法. -耳小骨筋反射と聴性脳幹反応-耳展25. 1: 13-24, 1982.
5) STARR A and HAMILTON A E: Correlation between confirmed sites of neurelogical lesion and abnormalities of far-field auditory brainstem responses. Electroencephalogr Clin Neurophysiol 41: 595-608, 1976.
13) 加我君孝他: 聴性脳幹反応 (Auditory Brain Stem Response-BSR) の脳幹障害症例への診断学的応用. 脳と神経29. 7: 87-97, 1977.
2) LEV A and SOHMER H: Sources of averaged neural responses recorded in animal and human subjects during cochlear audiometry (Electro-cochleogram). Arch Klin Exp Ohren Nasen Kehlkopfheilkd, 201: 79-90, 1972.
11) EGGERMONT J J et al.: Electrocochleography and auditory brainstem electricr esponses in patients with pontine angle tumors. Ann Otol Rhinol Laryngol. (Suppl) 75: 1-19, 1980.
21) NORDAR R KINNEY S E: The contralateral effects of large tumors on brainstem auditory evoked potentials. Laryngoscope 90: 1762-1768, 1980.
1) JEWETT D L et al: Human auditory evoked potentials: Possible brain stem components detected on the scalp. Science 167: 1517-1518, 1970.
10) HOUSE J W and BRACKMANN D E: Brain stem audiometry in neuro to logic diagnosis. Arch Otolaryngol., 105: 305-309, 1979.
9) CLEMIE J D & MCGEK T: Brain stem electric response audiometry in the differential diagnosis of acoustic tumors. The Laryngoscope, 89: 31-42, 1979.
19) COATS A C: Human auditory nerve action potentials and brain stem evoked responses.: Latency-intensity functions in detection of cochlear and retrocochlear abnormality. Arch Otolaryngol 104: 709-717, 1978.
8) SELTERS W A & BRACKMANN D E: Aco ustic tumor detection with brain stem electric response auditometry. Arch Otolaryngol 103: 181-187, 1977.
23) ALLEN A R & START A: Auditory brain stem potentials in monkey (M. MULATTA) and man. Electroenceph Clin Neurophysiol 45: 53-63, 1978.
15) 六郷正暁他: 小脳橋角部腫瘍における聴生脳幹反応の検討. 耳鼻臨床73. 7: 1159-1168, 1980.
12) 細川智: 聴神経腫瘍とその他の小脳橋角部腫瘍におけるBSR. Audiol Jpn 20: 158-163, 1977.
22) 細谷睦他: 頭蓋内疾患に対するABRの臨床応用. 耳鼻臨床74. 8: 1715-1725, 1981.
16) 神崎仁他: 聴神経腫瘍の診断法としてのAuditory Brain stem Response. Audiol Jpn23: 34-43, 1980.
4) 安藤一郎: BSRの実験的研究 (下丘破壊による BSRの変化). Audiol Jpn 20: 210-220, 1977.
20) KIMURA R & PERLMAN H B: Arterial obstruction of the labyrinth part I. cochlear changes. Ann. Otol 67: 5-24, 1958.
18) THOMSEN J et al.: Auditory brain stem responses in patients with acoustic neuromas. Acta Otolaryngol Supple. 386: 20-22, 1982.
6) STOCKARD J J and ROSSITER V S: Clinical and pathologic correlates of brain stem auditory response abnormalities. Neurology 27: 316-325, 1977.
7) CHINN J & MILLER J: Animal model of acoustic neuroma. Arch Otolaryngol. 101: 222-226, 1975.
References_xml – reference: 23) ALLEN A R & START A: Auditory brain stem potentials in monkey (M. MULATTA) and man. Electroenceph Clin Neurophysiol 45: 53-63, 1978.
– reference: 6) STOCKARD J J and ROSSITER V S: Clinical and pathologic correlates of brain stem auditory response abnormalities. Neurology 27: 316-325, 1977.
– reference: 13) 加我君孝他: 聴性脳幹反応 (Auditory Brain Stem Response-BSR) の脳幹障害症例への診断学的応用. 脳と神経29. 7: 87-97, 1977.
– reference: 15) 六郷正暁他: 小脳橋角部腫瘍における聴生脳幹反応の検討. 耳鼻臨床73. 7: 1159-1168, 1980.
– reference: 11) EGGERMONT J J et al.: Electrocochleography and auditory brainstem electricr esponses in patients with pontine angle tumors. Ann Otol Rhinol Laryngol. (Suppl) 75: 1-19, 1980.
– reference: 7) CHINN J & MILLER J: Animal model of acoustic neuroma. Arch Otolaryngol. 101: 222-226, 1975.
– reference: 8) SELTERS W A & BRACKMANN D E: Aco ustic tumor detection with brain stem electric response auditometry. Arch Otolaryngol 103: 181-187, 1977.
– reference: 3) BUCHWALD J. S and HUANG C M: Far-field acoustic response: Origins in the cat. Science 189: 382-384, 1975.
– reference: 12) 細川智: 聴神経腫瘍とその他の小脳橋角部腫瘍におけるBSR. Audiol Jpn 20: 158-163, 1977.
– reference: 4) 安藤一郎: BSRの実験的研究 (下丘破壊による BSRの変化). Audiol Jpn 20: 210-220, 1977.
– reference: 14) 柏木譲治他: 小脳橋角部障害へのBSRの応用. 日耳鼻81: 578-586, 1978.
– reference: 17) 神崎仁他: 聴神経腫瘍の他覚的聴覚検査診断法. -耳小骨筋反射と聴性脳幹反応-耳展25. 1: 13-24, 1982.
– reference: 22) 細谷睦他: 頭蓋内疾患に対するABRの臨床応用. 耳鼻臨床74. 8: 1715-1725, 1981.
– reference: 10) HOUSE J W and BRACKMANN D E: Brain stem audiometry in neuro to logic diagnosis. Arch Otolaryngol., 105: 305-309, 1979.
– reference: 19) COATS A C: Human auditory nerve action potentials and brain stem evoked responses.: Latency-intensity functions in detection of cochlear and retrocochlear abnormality. Arch Otolaryngol 104: 709-717, 1978.
– reference: 20) KIMURA R & PERLMAN H B: Arterial obstruction of the labyrinth part I. cochlear changes. Ann. Otol 67: 5-24, 1958.
– reference: 1) JEWETT D L et al: Human auditory evoked potentials: Possible brain stem components detected on the scalp. Science 167: 1517-1518, 1970.
– reference: 9) CLEMIE J D & MCGEK T: Brain stem electric response audiometry in the differential diagnosis of acoustic tumors. The Laryngoscope, 89: 31-42, 1979.
– reference: 21) NORDAR R KINNEY S E: The contralateral effects of large tumors on brainstem auditory evoked potentials. Laryngoscope 90: 1762-1768, 1980.
– reference: 16) 神崎仁他: 聴神経腫瘍の診断法としてのAuditory Brain stem Response. Audiol Jpn23: 34-43, 1980.
– reference: 2) LEV A and SOHMER H: Sources of averaged neural responses recorded in animal and human subjects during cochlear audiometry (Electro-cochleogram). Arch Klin Exp Ohren Nasen Kehlkopfheilkd, 201: 79-90, 1972.
– reference: 18) THOMSEN J et al.: Auditory brain stem responses in patients with acoustic neuromas. Acta Otolaryngol Supple. 386: 20-22, 1982.
– reference: 5) STARR A and HAMILTON A E: Correlation between confirmed sites of neurelogical lesion and abnormalities of far-field auditory brainstem responses. Electroencephalogr Clin Neurophysiol 41: 595-608, 1976.
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Snippet In 25 patients with confirmed acoustic and cerebellopontine angle tumours seen in our clinic from 1979 to 1983, the auditory brainstem responses (ABR) were...
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聴神経腫瘍
Title Auditory Brainstem Responses and the Diagnosis of Acoustic and C-P angle Tumours
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