Evaluation of invasiveness of full-endoscopic spine surgery based on blood data
Introduction: Full-endoscopic spine surgery (FESS) using transforaminal (TF) approach can be performed through an 8 mm skin incision under local anesthesia and is considered a minimally invasive spine surgery. The minimal invasiveness of FESS was evaluated using pre- and postoperative blood data.Mat...
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| Published in | Journal of Spine Research Vol. 14; no. 8; pp. 1080 - 1085 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
The Japanese Society for Spine Surgery and Related Research
20.08.2023
一般社団法人 日本脊椎脊髄病学会 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1884-7137 2435-1563 |
| DOI | 10.34371/jspineres.2023-0802 |
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| Abstract | Introduction: Full-endoscopic spine surgery (FESS) using transforaminal (TF) approach can be performed through an 8 mm skin incision under local anesthesia and is considered a minimally invasive spine surgery. The minimal invasiveness of FESS was evaluated using pre- and postoperative blood data.Material and Methods: The subjects of this study were 68 patients (39 males and 29 females) who underwent TF-FESS (FESS group), 24 patients (18 males and 6 females) who underwent laminectomy (L group), and 76 patients (38 males and 38 females) who underwent posterior interbody fusion (F group) for lumbar disc herniation and lumbar spinal canal stenosis between 1 vertebra from April 2021 to July 2022. The mean age of TF-FESS, laminectomy, and lumbar interbody fusion were 53.6, 73.2, and 71.0 years old. Preoperative and postoperative day 1 blood data were used.The items examined were creatinine kinase (CK), C-reactive protein (CRP), white blood cell count (WBC), and hemoglobin (Hb). The amount of change in each item in the FESS group was determined and compared with the L and F groups.Results: CK did not differ pre- and postoperatively in the FESS group (130 U/L vs 114 U/L, P=0.06), but was significantly increased postoperatively in the L group (158 U/L vs 269 U/L, P<0.05) and F groups (128 U/L vs 584 U/L, P<0.05). CRP did not differ pre- and postoperatively in the FESS group (0.44 mg/dL vs 0.51 mg/dL, P=0.35) and the L group (0.08 mg/dL vs 0.75 mg/dL, P=0.08), but was significantly increased postoperatively in the F group (0.34 mg/dL vs 1.24 mg/dL, P<0.05). WBC did not differ pre- and postoperatively in the FESS group (6,757/μL vs 6,982/μL, P=0.22), but was significantly increased postoperatively in the L (6,188/μL vs 9,263/μL, P<0.05) and F groups (6,137/μL vs 10,108/μL, P<0.05). Hb was significantly decreased postoperatively in the FESS group (13.9 g/dL vs 13.5 g/dL, P<0.05), L group (13.9 g/dL vs 12.3 g/dL, P<0.05) and F group (13.1 g/dL vs 11.2 g/dL, P<0.05). Comparison of pre- and postoperative changes showed significant differences among the three groups for all items.Conclusion: The results of this study show that TF-FESS is a minimally invasive spine surgery in terms of blood data. |
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| AbstractList | Introduction: Full-endoscopic spine surgery (FESS) using transforaminal (TF) approach can be performed through an 8 mm skin incision under local anesthesia and is considered a minimally invasive spine surgery. The minimal invasiveness of FESS was evaluated using pre- and postoperative blood data.Material and Methods: The subjects of this study were 68 patients (39 males and 29 females) who underwent TF-FESS (FESS group), 24 patients (18 males and 6 females) who underwent laminectomy (L group), and 76 patients (38 males and 38 females) who underwent posterior interbody fusion (F group) for lumbar disc herniation and lumbar spinal canal stenosis between 1 vertebra from April 2021 to July 2022. The mean age of TF-FESS, laminectomy, and lumbar interbody fusion were 53.6, 73.2, and 71.0 years old. Preoperative and postoperative day 1 blood data were used.The items examined were creatinine kinase (CK), C-reactive protein (CRP), white blood cell count (WBC), and hemoglobin (Hb). The amount of change in each item in the FESS group was determined and compared with the L and F groups.Results: CK did not differ pre- and postoperatively in the FESS group (130 U/L vs 114 U/L, P=0.06), but was significantly increased postoperatively in the L group (158 U/L vs 269 U/L, P<0.05) and F groups (128 U/L vs 584 U/L, P<0.05). CRP did not differ pre- and postoperatively in the FESS group (0.44 mg/dL vs 0.51 mg/dL, P=0.35) and the L group (0.08 mg/dL vs 0.75 mg/dL, P=0.08), but was significantly increased postoperatively in the F group (0.34 mg/dL vs 1.24 mg/dL, P<0.05). WBC did not differ pre- and postoperatively in the FESS group (6,757/μL vs 6,982/μL, P=0.22), but was significantly increased postoperatively in the L (6,188/μL vs 9,263/μL, P<0.05) and F groups (6,137/μL vs 10,108/μL, P<0.05). Hb was significantly decreased postoperatively in the FESS group (13.9 g/dL vs 13.5 g/dL, P<0.05), L group (13.9 g/dL vs 12.3 g/dL, P<0.05) and F group (13.1 g/dL vs 11.2 g/dL, P<0.05). Comparison of pre- and postoperative changes showed significant differences among the three groups for all items.Conclusion: The results of this study show that TF-FESS is a minimally invasive spine surgery in terms of blood data.
はじめに:経椎間孔アプローチ全内視鏡下脊椎手術(transforaminal full-endoscopic spine surgery;TF-FESS)は低侵襲脊椎手術と言われているが低侵襲性について報告した研究は少ない.本研究はTF-FESSの低侵襲性を,血液データを用いて評価した.対象と方法:2021年4月から2022年7月に当院で腰椎椎間板ヘルニア,腰部脊柱管狭窄症に対し,1椎間のTF-FESS(局所麻酔下)を施行した68例,椎弓切除術を施行した24例,後方椎体間固定術を施行した76例を対象とし,平均年齢はそれぞれ,53.6歳,73.2歳,71.0歳であった.術前と術後1日目の血液検査にて,クレアチニンキナーゼ(CK),C反応性蛋白(CRP),白血球数(WBC),ヘモグロビン量(Hb)の平均値を比較し,変化量(Δ)の平均値を3群間で比較検討した.結果:TF-FESS群において,CK(術前130(U/L)vs術後114(U/L).P=0.06),CRP(術前0.44(mg/dL)vs術後0.51(mg/dL).P=0.35),WBC(術前6,757(/μL)vs術後6,982(/μL).P=0.22)は術前後で差はなく,Hb(術前13.9(g/dL)vs術後13.5(g/dL).P<0.05)は術後有意に低下した.変化量の比較ではTF-FESS群,椎弓切除群,後方椎体間固定群の順にΔCK(-17.0(U/L)vs 112(U/L)vs 456(U/L).P<0.05),ΔCRP(0.07(mg/dL)vs 0.67(mg/dL)vs 0.90(mg/dL).P<0.05),ΔWBC(225(/μL)vs 3,075(/μL)vs 3,971(/μL).P<0.05),ΔHb(-0.40(g/dL)vs-1.54(g/dL)vs-1.90(g/dL).P<0.05)と,全項目でTF-FESS群が他の2群と比べ有意に変化が少なかった. Introduction: Full-endoscopic spine surgery (FESS) using transforaminal (TF) approach can be performed through an 8 mm skin incision under local anesthesia and is considered a minimally invasive spine surgery. The minimal invasiveness of FESS was evaluated using pre- and postoperative blood data.Material and Methods: The subjects of this study were 68 patients (39 males and 29 females) who underwent TF-FESS (FESS group), 24 patients (18 males and 6 females) who underwent laminectomy (L group), and 76 patients (38 males and 38 females) who underwent posterior interbody fusion (F group) for lumbar disc herniation and lumbar spinal canal stenosis between 1 vertebra from April 2021 to July 2022. The mean age of TF-FESS, laminectomy, and lumbar interbody fusion were 53.6, 73.2, and 71.0 years old. Preoperative and postoperative day 1 blood data were used.The items examined were creatinine kinase (CK), C-reactive protein (CRP), white blood cell count (WBC), and hemoglobin (Hb). The amount of change in each item in the FESS group was determined and compared with the L and F groups.Results: CK did not differ pre- and postoperatively in the FESS group (130 U/L vs 114 U/L, P=0.06), but was significantly increased postoperatively in the L group (158 U/L vs 269 U/L, P<0.05) and F groups (128 U/L vs 584 U/L, P<0.05). CRP did not differ pre- and postoperatively in the FESS group (0.44 mg/dL vs 0.51 mg/dL, P=0.35) and the L group (0.08 mg/dL vs 0.75 mg/dL, P=0.08), but was significantly increased postoperatively in the F group (0.34 mg/dL vs 1.24 mg/dL, P<0.05). WBC did not differ pre- and postoperatively in the FESS group (6,757/μL vs 6,982/μL, P=0.22), but was significantly increased postoperatively in the L (6,188/μL vs 9,263/μL, P<0.05) and F groups (6,137/μL vs 10,108/μL, P<0.05). Hb was significantly decreased postoperatively in the FESS group (13.9 g/dL vs 13.5 g/dL, P<0.05), L group (13.9 g/dL vs 12.3 g/dL, P<0.05) and F group (13.1 g/dL vs 11.2 g/dL, P<0.05). Comparison of pre- and postoperative changes showed significant differences among the three groups for all items.Conclusion: The results of this study show that TF-FESS is a minimally invasive spine surgery in terms of blood data. |
| Author | Takagi, Kei Maruo, Keishi Arizumi, Fumihiro Tachibana, Toshiya Kishima, Kazuya Yoshie, Norichika Kusukawa, Tomoyuki |
| Author_FL | 木島 和也 楠川 智之 有住 文博 高木 啓 橘 俊哉 圓尾 圭史 吉江 範親 |
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| Author_xml | – sequence: 1 fullname: Kishima, Kazuya organization: Department of orthopaedics, Hyogo Medical University – sequence: 1 fullname: Tachibana, Toshiya organization: Department of orthopaedics, Hyogo Medical University – sequence: 1 fullname: Yoshie, Norichika organization: Department of orthopaedics, Hyogo Medical University – sequence: 1 fullname: Maruo, Keishi organization: Department of orthopaedics, Hyogo Medical University – sequence: 1 fullname: Kusukawa, Tomoyuki organization: Department of orthopaedics, Hyogo Medical University – sequence: 1 fullname: Takagi, Kei organization: Department of orthopaedics, Hyogo Medical University – sequence: 1 fullname: Arizumi, Fumihiro organization: Department of orthopaedics, Hyogo Medical University |
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| References | 2) 尾市 健: 90歳以上超高齢者の脊椎手術における周術期リスク. Bone Joint Nerve. 2019; 9 (1): 113-120 7) Kishima K, Yagi K, Yamashita K, et al: Transforaminal full-endoscopic ventral facetectomy: mid-term results and factors associated with poor surgical outcomes. Journal of Neurological Surgery Part A: Central European Neurosurgery. 2022. doi: 10.1055/a-1995-1772 4) Sheng-En Chou, Cheng-Shyuan Rau, Yu-Chin Tsai, et al: Risk factors and complications contributing to mortality in elderly patients with fall-induced femoral fracture: A cross-sectional analysis based on trauma registry date of 2407 patients. International Journal of Surgery. 2019; 66: 48-52 8) Kanda Y: Investigation of the freely available easy-to-use software 'EZR' for medical statistics. Bone Marrow Transplantation. 2013; 48: 452-458 11) Fujita M, Inui T, Oshima Y, et al: Comparison of the Outcomes of Microendoscopic Discectomy Versus Full-Endoscopic Discectomy for the Treatment of L4/5 Lumbar Disc Herniation. Global Spine Journal. 2022; 0 (0): 1-8 9) Lei Pan, Peifang Zhang, Qingshui Yin: Comparison of tissue damages caused by endoscopic lumbar discectomy and traditional lumbar discectomy: A randomized controlled trial. International Journal of Surgery. 2014; 12: 534-537 3) LS Rasmussen, T Johnson, H Kuipers, et al: Does anaesthesia cause postoperative cognitive dysfunction? A randomized study of regional versus general anaesthesia in 438 elderly patients. Acta Anaesthesiol Scand. 2003; 47: 260-266 1) Nohara Y, Taneichi H, Ueyama K, et al: Nationwide survey on complications of spine surgery in Japan. Journal of Orthopaedic Science. 2004; 9 (5): 424-433 6) Sairyo K, Yamashita K, Manabe H, et al: A novel surgical concept of transforaminal full-endscopic lumbar undercutting laminectomy (TE-LUL) for central canal stenosis of the lumbar spine with local anesthesia: A case report and literature review. The Journal of Medical Investigation. 2019; 66: 224-229 10) 中道清広, 渡邉泰伸, 河野 仁, 他: 腰椎椎間板ヘルニアに対するFull-endoscopic spine surgeryの手術成績. Bone Joint Nerve. 2019; 9 (4): 475-481 5) Rock Peter, Rich Preston B: Postoperative pulmonary complications. Current Opinion in Anesthesiology. 2003; 16 (2): 123-131 |
| References_xml | – reference: 9) Lei Pan, Peifang Zhang, Qingshui Yin: Comparison of tissue damages caused by endoscopic lumbar discectomy and traditional lumbar discectomy: A randomized controlled trial. International Journal of Surgery. 2014; 12: 534-537 – reference: 10) 中道清広, 渡邉泰伸, 河野 仁, 他: 腰椎椎間板ヘルニアに対するFull-endoscopic spine surgeryの手術成績. Bone Joint Nerve. 2019; 9 (4): 475-481 – reference: 2) 尾市 健: 90歳以上超高齢者の脊椎手術における周術期リスク. Bone Joint Nerve. 2019; 9 (1): 113-120 – reference: 6) Sairyo K, Yamashita K, Manabe H, et al: A novel surgical concept of transforaminal full-endscopic lumbar undercutting laminectomy (TE-LUL) for central canal stenosis of the lumbar spine with local anesthesia: A case report and literature review. The Journal of Medical Investigation. 2019; 66: 224-229 – reference: 5) Rock Peter, Rich Preston B: Postoperative pulmonary complications. Current Opinion in Anesthesiology. 2003; 16 (2): 123-131 – reference: 8) Kanda Y: Investigation of the freely available easy-to-use software 'EZR' for medical statistics. Bone Marrow Transplantation. 2013; 48: 452-458 – reference: 1) Nohara Y, Taneichi H, Ueyama K, et al: Nationwide survey on complications of spine surgery in Japan. Journal of Orthopaedic Science. 2004; 9 (5): 424-433 – reference: 4) Sheng-En Chou, Cheng-Shyuan Rau, Yu-Chin Tsai, et al: Risk factors and complications contributing to mortality in elderly patients with fall-induced femoral fracture: A cross-sectional analysis based on trauma registry date of 2407 patients. International Journal of Surgery. 2019; 66: 48-52 – reference: 3) LS Rasmussen, T Johnson, H Kuipers, et al: Does anaesthesia cause postoperative cognitive dysfunction? A randomized study of regional versus general anaesthesia in 438 elderly patients. Acta Anaesthesiol Scand. 2003; 47: 260-266 – reference: 11) Fujita M, Inui T, Oshima Y, et al: Comparison of the Outcomes of Microendoscopic Discectomy Versus Full-Endoscopic Discectomy for the Treatment of L4/5 Lumbar Disc Herniation. Global Spine Journal. 2022; 0 (0): 1-8 – reference: 7) Kishima K, Yagi K, Yamashita K, et al: Transforaminal full-endoscopic ventral facetectomy: mid-term results and factors associated with poor surgical outcomes. Journal of Neurological Surgery Part A: Central European Neurosurgery. 2022. doi: 10.1055/a-1995-1772 |
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| SubjectTerms | Blood data full-endoscopic spine surgery; FESS minimally invasive surgery transforaminal approach 低侵襲手術 全内視鏡下脊椎手術 経椎間孔アプローチ 血液データ |
| Title | Evaluation of invasiveness of full-endoscopic spine surgery based on blood data |
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