Long-term Outcomes of Er: YAG Laser Microsurgery for Melanin Removal in Gingiva: A Case Report

Purpose: To describe the long-term outcomes of a case of severe gingival melanin removal using an erbium-doped yttrium aluminum garnet laser (Er: YAG) laser (Dentlite, HOYA ConBio) under the microscope. Methods: The patient provided informed consent prior to the presentation of this case report. A 2...

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Published inThe Japanese Journal of Conservative Dentistry Vol. 66; no. 2; pp. 147 - 153
Main Authors Go, INOUE, Yasushi, SHIMADA, Akira, AOKI, Koji, MIZUTANI, Risako, MIKAMI
Format Journal Article
LanguageJapanese
Published The Japanese Society of Conservative Dentistry 30.04.2023
特定非営利活動法人 日本歯科保存学会
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ISSN0387-2343
2188-0808
DOI10.11471/shikahozon.66.147

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Abstract Purpose: To describe the long-term outcomes of a case of severe gingival melanin removal using an erbium-doped yttrium aluminum garnet laser (Er: YAG) laser (Dentlite, HOYA ConBio) under the microscope. Methods: The patient provided informed consent prior to the presentation of this case report. A 29-year-old male, with a smoking habit of nearly 10 cigarettes per day, presented with a chief complaint of esthetic disorder in the mandibular anterior gingiva. Extensive melanin deposition was observed on the attached gingiva of the mandibular anterior teeth. Before the melanin removal procedure, he was first advised to quit smoking to prevent recurrence. Then, we planned gingival ablation of the melanin pigmentation area using an Er: YAG laser under a microscope. Results: The advice to quit smoking was successful. Local anesthesia was administered to the mandibular anterior teeth, and gingival ablation of melanin pigmentation sites was performed using the Er: YAG laser at 10-30 Hz and 80 mJ (panel display), using contact tips under water spray. By performing the microsurgery, the remaining subtle pigmented areas were easily visible, allowing for a more precise procedure. The magnified view facilitated careful tissue ablation in areas susceptible to postoperative gingival recession, such as the gingival margin and interdental papillary area. There was no obvious coagulation or carbonization on the laser-irradiated surface, and connective tissue exposure was observed after epithelial tissue ablation. Postoperative analgesia or antibacterial medication was not administered because invasion was minimal. Epithelialization was completed 7 days postoperatively. Melanin removal on the buccal side of the mandibular anterior teeth was divided into three sessions to complete the treatment. At 1 year and 6 months postoperatively, the improved gingival esthetics were well maintained. Mild to moderate recurrence was observed 16 years later. Conclusion: Minimally invasive removal of severe melanin pigmentation of the gingiva under a microscope using an Er: YAG laser resulted in a favorable healing outcome. This case suggests that microsurgical depigmentation using an Er: YAG laser could achieve and maintain medium-term sound outcomes for the treatment of gingival esthetic disorders.
AbstractList Purpose: To describe the long-term outcomes of a case of severe gingival melanin removal using an erbium-doped yttrium aluminum garnet laser (Er: YAG) laser (Dentlite, HOYA ConBio) under the microscope. Methods: The patient provided informed consent prior to the presentation of this case report. A 29-year-old male, with a smoking habit of nearly 10 cigarettes per day, presented with a chief complaint of esthetic disorder in the mandibular anterior gingiva. Extensive melanin deposition was observed on the attached gingiva of the mandibular anterior teeth. Before the melanin removal procedure, he was first advised to quit smoking to prevent recurrence. Then, we planned gingival ablation of the melanin pigmentation area using an Er: YAG laser under a microscope. Results: The advice to quit smoking was successful. Local anesthesia was administered to the mandibular anterior teeth, and gingival ablation of melanin pigmentation sites was performed using the Er: YAG laser at 10-30 Hz and 80 mJ (panel display), using contact tips under water spray. By performing the microsurgery, the remaining subtle pigmented areas were easily visible, allowing for a more precise procedure. The magnified view facilitated careful tissue ablation in areas susceptible to postoperative gingival recession, such as the gingival margin and interdental papillary area. There was no obvious coagulation or carbonization on the laser-irradiated surface, and connective tissue exposure was observed after epithelial tissue ablation. Postoperative analgesia or antibacterial medication was not administered because invasion was minimal. Epithelialization was completed 7 days postoperatively. Melanin removal on the buccal side of the mandibular anterior teeth was divided into three sessions to complete the treatment. At 1 year and 6 months postoperatively, the improved gingival esthetics were well maintained. Mild to moderate recurrence was observed 16 years later. Conclusion: Minimally invasive removal of severe melanin pigmentation of the gingiva under a microscope using an Er: YAG laser resulted in a favorable healing outcome. This case suggests that microsurgical depigmentation using an Er: YAG laser could achieve and maintain medium-term sound outcomes for the treatment of gingival esthetic disorders.  緒言:Er:YAGレーザーの発振波長2,940nmは水への吸収性が非常に高く,軟組織・硬組織ともに効率よく蒸散できる.特に歯肉の蒸散においてEr:YAGレーザーは周囲組織への熱の影響がきわめて少なく,臨床において歯肉切除術や小帯切除術などの軟組織治療だけでなく,歯肉色素沈着除去やメタルタトゥー除去などに応用されている.そこで,Er:YAGレーザーを用いて歯肉のメラニン除去をマイクロサージェリーで実施した症例の長期経過を報告する. 症例:患者は29歳男性,喫煙者で1日10本の喫煙があり,歯肉の審美障害を主訴に来院した.下顎前歯部の付着歯肉に広範囲にメラニン沈着を認めた.治療の開始にあたり,まず禁煙指導を行い,そのうえで重度のメラニン色素沈着部位の歯肉蒸散に対してEr:YAGレーザーを用い手術用顕微鏡下で行うことを計画した. 成績:禁煙指導は奏功し,喫煙習慣がない状態で処置を行った.下顎前歯部の歯肉頰移行部および歯間乳頭部に局所麻酔を行い,Er:YAGレーザー(Dentlite,HOYA ConBio)を10~30Hz,パネル出力設定80 mJ,注水下にて,2種類のコンタクトチップを用いてメラニン色素沈着部位の歯肉蒸散を行った.マイクロサージェリーとして行うことで,残存する微細な色素沈着領域をより確実に視認でき,正確で安全な処置が可能であった.歯肉縁や歯間乳頭部など術後の歯肉退縮を偶発しやすい部位においても,拡大視野下であることにより慎重な組織蒸散が容易であった.レーザー照射面には明らかな凝固変性や炭化はなく,上皮を蒸散した面には白色の結合組織の露出を認めたが,侵襲は非常に軽度なため術後の鎮痛薬や抗菌薬などの投薬は行わなかった.創面の治癒は良好かつ迅速で,術後7日には上皮化が認められた.本症例では下顎前歯部唇側のメラニン除去を3回に分けて治療を完了した.術後1年6カ月には色素沈着の再発はほとんどみられず,きわめて良好な経過であった.術後16年後には軽度から中等度の再発が生じていた. 結論:本症例では,喫煙により歯肉に著しく沈着したメラニン色素を,Er:YAGレーザーをマイクロサージェリーにて応用することで低侵襲に処置を行うことができ,良好な治癒成績が得られた.歯肉の審美障害の治療にEr:YAGレーザーをマイクロサージェリーで使用する有効性が示唆され,中期的にも良好な経過を維持できた.
Purpose: To describe the long-term outcomes of a case of severe gingival melanin removal using an erbium-doped yttrium aluminum garnet laser (Er: YAG) laser (Dentlite, HOYA ConBio) under the microscope. Methods: The patient provided informed consent prior to the presentation of this case report. A 29-year-old male, with a smoking habit of nearly 10 cigarettes per day, presented with a chief complaint of esthetic disorder in the mandibular anterior gingiva. Extensive melanin deposition was observed on the attached gingiva of the mandibular anterior teeth. Before the melanin removal procedure, he was first advised to quit smoking to prevent recurrence. Then, we planned gingival ablation of the melanin pigmentation area using an Er: YAG laser under a microscope. Results: The advice to quit smoking was successful. Local anesthesia was administered to the mandibular anterior teeth, and gingival ablation of melanin pigmentation sites was performed using the Er: YAG laser at 10-30 Hz and 80 mJ (panel display), using contact tips under water spray. By performing the microsurgery, the remaining subtle pigmented areas were easily visible, allowing for a more precise procedure. The magnified view facilitated careful tissue ablation in areas susceptible to postoperative gingival recession, such as the gingival margin and interdental papillary area. There was no obvious coagulation or carbonization on the laser-irradiated surface, and connective tissue exposure was observed after epithelial tissue ablation. Postoperative analgesia or antibacterial medication was not administered because invasion was minimal. Epithelialization was completed 7 days postoperatively. Melanin removal on the buccal side of the mandibular anterior teeth was divided into three sessions to complete the treatment. At 1 year and 6 months postoperatively, the improved gingival esthetics were well maintained. Mild to moderate recurrence was observed 16 years later. Conclusion: Minimally invasive removal of severe melanin pigmentation of the gingiva under a microscope using an Er: YAG laser resulted in a favorable healing outcome. This case suggests that microsurgical depigmentation using an Er: YAG laser could achieve and maintain medium-term sound outcomes for the treatment of gingival esthetic disorders.
Author Akira, AOKI
Risako, MIKAMI
Yasushi, SHIMADA
Koji, MIZUTANI
Go, INOUE
Author_FL 水谷 幸嗣
青木 章
井上 剛
三上 理沙子
島田 康史
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  organization: Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)
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  fullname: Risako, MIKAMI
  organization: Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)
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References_xml – reference: 3) Mavrogiannis M, Ellis JS, Seymour RA, Thomason JM. The efficacy of three different surgical techniques in the management of drug-induced gingival overgrowth. J Clin Periodontol 2006; 33: 677-682.
– reference: 27) Simşek Kaya G, Yapici Yavuz G, Sümbüllü MA, Dayi E. A comparison of diode laser and Er: YAG lasers in the treatment of gingival melanin pigmentation. Oral Surg Oral Med Oral Pathol Oral Radiol 2012; 113: 293-299.
– reference: 25) Esen E, Haytac MC, Oz IA, Erdoğan O, Karsli ED. Gingival melanin pigmentation and its treatment with the CO2 laser. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 98: 522-527.
– reference: 15) Mizutani K, Shioyama H, Matsuura T, Mikami R, Takeda K, Izumi Y, Aoki A, Iwata T. Periodontal regenerative therapy in patients with type 2 diabetes using minimally invasive surgical technique with enamel matrix derivative under 3-year observation: A prospective cohort study. J Periodontol 2021; 92: 1262-1273.
– reference: 13) 石井さやか, 青木 章, 川嶋庸子, 渡辺 久, 石川 烈. Er : YAGレーザーの歯肉メラニン除去への応用―術式ならびに臨床的予後評価について―. 日レ歯誌 2002 ; 13 : 89-96.
– reference: 18) Ishikawa I, Aoki A, Takasaki AA. Potential applications of Erbium: YAG laser in periodontics. J Periodontal Res 2004; 39: 275-285.
– reference: 24) Axéll T, Hedin CA. Epidemiologic study of excessive oral melanin pigmentation with special reference to the influence of tobacco habits. Scand J Dent Res 1982; 90: 434-442.
– reference: 7) Lin YH, Tu YK, Lu CT, Chung WC, Huang CF, Huang MS, Lu HK. Systematic review of treatment modalities for gingival depigmentation: a random-effects poisson regression analysis. J Esthet Restor Dent 2014; 26: 162-178.
– reference: 17) Mizutani K, Mikami R, Tsukui A, Nagai S, Pavlic V, Komada W, Iwata T, Aoki A. Novel flapless esthetic procedure for the elimination of extended gingival metal tattoos adjacent to prosthetic teeth: Er: YAG laser micro-keyhole surgery. J Prosthodont Res 2022; 66: 346-352.
– reference: 8) Abduljabbar T, Vohra F, Akram Z, Ghani SMA, Al-Hamoudi N, Javed F. Efficacy of surgical laser therapy in the management of oral pigmented lesions: A systematic review. J Photochem Photobiol B 2017; 173: 353-359.
– reference: 26) Atsawasuwan P, Greethong K, Nimmanon V. Treatment of gingival hyperpigmentation for esthetic purposes by Nd: YAG laser: report of 4 cases. J Periodontol 2000; 71: 315-321.
– reference: 21) 三枝英敏, 渡辺 聡, 安生智郎, 海老原 新, 須田英明. 歯科用レーザー使用と眼球への安全性 : 防護眼鏡着用下および顕微鏡下での使用について. 日歯保存誌 2007 ; 50 : 432-439.
– reference: 16) Mikami R, Mizutani K, Nagai S, Pavlic V, Iwata T, Aoki A. A novel minimally-invasive approach for metal tattoo removal with Er: YAG laser. J Esthet Restor Dent 2021; 33: 550-559.
– reference: 23) Araki S, Murata K, Ushio K, Sakai R. Dose-response relationship between tobacco consumption and melanin pigmentation in the attached gingiva. Arch Environ Health 1983; 38: 375-378.
– reference: 20) 吉田憲司, 嶋倉道郎, 安孫子宜光, 大槻昌幸, 木村裕一, 田中秀生, 都賀谷紀宏, 永井茂之. 歯科用レーザーを安全に使用するための指針. 日レ歯誌 2012 ; 23 : 147-150.
– reference: 5) Mizutani K, Aoki A, Coluzzi D, Yukna R, Wang CY, Pavlic V, Izumi Y. Lasers in minimally invasive periodontal and peri-implant therapy. Periodontol 2000 2016; 71: 185-212.
– reference: 14) Clementini M, Ambrosi A, Cicciarelli V, De Risi V, de Sanctis M. Clinical performance of minimally invasive periodontal surgery in the treatment of infrabony defects: Systematic review and meta-analysis. J Clin Periodontol 2019; 46: 1236-1253.
– reference: 2) Hosaka K, Tichy A, Motoyama Y, Mizutani K, Lai WJ, Kanno Z, Tagami J, Nakajima M. Post-orthodontic recontouring of anterior teeth using composite injection technique with a digital workflow. J Esthet Restor Dent 2020; 32: 638-644.
– reference: 12) Pavlic V, Brkic Z, Marin S, Cicmil S, Gojkov-Vukelic M, Aoki A. Gingival melanin depigmentation by Er: YAG laser: A literature review. J Cosmet Laser Ther 2018; 20: 85-90.
– reference: 4) Aoki A, Mizutani K, Schwarz F, Sculean A, Yukna RA, Takasaki AA, Romanos GE, Taniguchi Y, Sasaki KM, Zeredo JL, Koshy G, Coluzzi DJ, White JM, Abiko Y, Ishikawa I, Izumi Y. Periodontal and peri-implant wound healing following laser therapy. Periodontol 2000 2015; 68: 217-269.
– reference: 10) 西田英作, 三木 学, 武藤昭紀, 窪川恵太, 片瀬剛士, 内田啓一, 阪中孝一郎, 大原盛勝, 大野友三, 吉成伸夫. 歯肉メラニン色素沈着症に対する歯科用 (Er : YAG, CO2) レーザーの着色除去効果. 日レ歯誌 2012 ; 23 : 27-32.
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Snippet Purpose: To describe the long-term outcomes of a case of severe gingival melanin removal using an erbium-doped yttrium aluminum garnet laser (Er: YAG) laser...
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SubjectTerms gingival pigmentation
laser
microsurgery
マイクロサージェリー
メラニン沈着
レーザー
Title Long-term Outcomes of Er: YAG Laser Microsurgery for Melanin Removal in Gingiva: A Case Report
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