Factors related to hyperuricemia Filed Survey Examination
Factors melated to hyperuricemia were examined in Tanushimaru, a farming community. Subjects were 849 males aged 40 to 69 who participated in this field survey in 1989. By multiple logistic regression analyisis, obesity (BMI≥ 25) and the medication with antihypertensive agents were significanty rela...
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| Published in | Journal of the Japanese Association for Cerebro-cardiovascular Disease Control Vol. 28; no. 2; pp. 89 - 93 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
The Japanese Association for Cerebro-cardiovascular Disease Control
30.10.1993
社団法人 日本循環器管理研究協議会 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0914-7284 |
| DOI | 10.11381/jjcdp1974.28.89 |
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| Abstract | Factors melated to hyperuricemia were examined in Tanushimaru, a farming community. Subjects were 849 males aged 40 to 69 who participated in this field survey in 1989. By multiple logistic regression analyisis, obesity (BMI≥ 25) and the medication with antihypertensive agents were significanty related to hyperuricemia. Obesity showed the highest relative risk, 2.20 (95%C.I. : 1.52-3.20). The positive relation between drinking habits and hyperuicemia has been widely accepted, but from this study that relationship is partially due to the indirect effect of drinking habits with weight gain intervening. High hemoglobin A1c level (HbA1 c > 6.0) did not show a significant relationship to hyperuricemia. |
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| AbstractList | Factors melated to hyperuricemia were examined in Tanushimaru, a farming community. Subjects were 849 males aged 40 to 69 who participated in this field survey in 1989.By multiple logistic regression analyisis, obesity (BMI≥ 25) and the medication with antihypertensive agents were significanty related to hyperuricemia. Obesity showed the highest relative risk, 2.20 (95%C.I. : 1.52-3.20).The positive relation between drinking habits and hyperuicemia has been widely accepted, but from this study that relationship is partially due to the indirect effect of drinking habits with weight gain intervening.High hemoglobin A1c level (HbA1 c > 6.0) did not show a significant relationship to hyperuricemia.
1989年の田主丸町における検診受診者, 男性849名 (40～69歳) を対象に, 地域集団での高尿酸血症の関連要因を検討した。有意な関連を示したのは, 肥満と高血圧治療であり, 最も強い関連があった肥満者の相対危険度は2.2倍であった。飲酒と高尿酸血症の関連も広く知られているが, その一部は肥満を介して作用していると考えられた。ヘモグロビンA1cが高値であることは, 高尿酸血症に関連を示さなかった。 Factors melated to hyperuricemia were examined in Tanushimaru, a farming community. Subjects were 849 males aged 40 to 69 who participated in this field survey in 1989. By multiple logistic regression analyisis, obesity (BMI≥ 25) and the medication with antihypertensive agents were significanty related to hyperuricemia. Obesity showed the highest relative risk, 2.20 (95%C.I. : 1.52-3.20). The positive relation between drinking habits and hyperuicemia has been widely accepted, but from this study that relationship is partially due to the indirect effect of drinking habits with weight gain intervening. High hemoglobin A1c level (HbA1 c > 6.0) did not show a significant relationship to hyperuricemia. |
| Author | Tashiro, Hiromi Adachi, Hisashi Hashimoto, Ryuichi Tsuruta, Makoto Toshima, Hironori |
| Author_FL | 戸嶋 裕徳 田代 寛美 鶴田 真 橋本 隆一 足達 寿 |
| Author_FL_xml | – sequence: 1 fullname: 足達 寿 – sequence: 2 fullname: 鶴田 真 – sequence: 3 fullname: 橋本 隆一 – sequence: 4 fullname: 田代 寛美 – sequence: 5 fullname: 戸嶋 裕徳 |
| Author_xml | – sequence: 1 fullname: Tsuruta, Makoto organization: Third Department of Internal Medicine, School of Medicine, Kurume University – sequence: 1 fullname: Toshima, Hironori organization: Third Department of Internal Medicine, School of Medicine, Kurume University – sequence: 1 fullname: Adachi, Hisashi organization: Third Department of Internal Medicine, School of Medicine, Kurume University – sequence: 1 fullname: Hashimoto, Ryuichi organization: Third Department of Internal Medicine, School of Medicine, Kurume University – sequence: 1 fullname: Tashiro, Hiromi organization: Labor Relations Division, Yawata Works, Nippon Steel Corporation |
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| References | 16) 大島良雄.痛風, 薬剤と高尿酸血症.東京医学社, 1976; 143-145. 11) Lieber, C. S., et al. Interrelation of uric acid and ethanol metabolism in man. J. Clin. Invest. 1962 : 41 : 1863-1870. 15) 国税庁課税部酒税課.「酒のしおり」, 1992; 33-35. 7) Nishizawa, T et al. Some factors related to obesity in the Japanese sumo wrestler. Am. J. Clin. Nutr. 1976 : 29 : 1167-1174. 6) 山内俊一, 藤森 新, 赤岡家雄.痛風.日本臨床, 1988 ; 46 : 123-126. 14) 藤森 新, 他. アルコール飲料中のプリン体含有量, 尿酸, 1985 : 9,128-133. 5) 緒方尚子.臨床栄養学提要・実習.医歯薬出版株式会社, 1988; 81-83. 3) 香川 綾, 監修.四訂食品成分表.科学技術庁資源調査会編.女子栄養大学出版部, 1986; 226-235. 13) Gibson, T., et al. A controlled study of diet in patients with gout. Ann Rheum Dis 1983 : 42,123-127. 4) 金井 泉, 金井正光.臨床検査法提要.金原出版株式会社, 1983; 432-436. 8) 山下静也, 他.高度肥満患者における尿酸代謝異常-尿酸排泄能の著明な低下と低カロリー食による改善.尿酸, 1984;8 : 92-99. 12) Faller, J., Fox, I. H. Ethanol-induced hyperuricemia. Evidence for increased urate production by activation of adenine nucleotide turnover. N Engl J Med 1982 : 307 : 1598-1602. 10) Hall, A. P., et al. Epidemiology of gout and hyperuricemia. Am. J. Med. 1967 : 42 : 27-37. 1) 西岡久寿樹.高尿酸血症.循環科学.丸善株式会社, 1992 ; 12 : 34-37. 9) French, J. G., et al. A study of familial aggregation of serum uric acid levels in the population of Tecumseh, Michigan, 1959-1960. Am. J. Epidemiol. 1967 ; 86 : 214-224. 2) Hiyamuta, K et al. Relationship between coro nary risk factor and arteriographic feature of coronary atherosclerosis. Jpn Circ J 1990 ; 54 : 442-447. |
| References_xml | – reference: 7) Nishizawa, T et al. Some factors related to obesity in the Japanese sumo wrestler. Am. J. Clin. Nutr. 1976 : 29 : 1167-1174. – reference: 8) 山下静也, 他.高度肥満患者における尿酸代謝異常-尿酸排泄能の著明な低下と低カロリー食による改善.尿酸, 1984;8 : 92-99. – reference: 15) 国税庁課税部酒税課.「酒のしおり」, 1992; 33-35. – reference: 6) 山内俊一, 藤森 新, 赤岡家雄.痛風.日本臨床, 1988 ; 46 : 123-126. – reference: 9) French, J. G., et al. A study of familial aggregation of serum uric acid levels in the population of Tecumseh, Michigan, 1959-1960. Am. J. Epidemiol. 1967 ; 86 : 214-224. – reference: 16) 大島良雄.痛風, 薬剤と高尿酸血症.東京医学社, 1976; 143-145. – reference: 13) Gibson, T., et al. A controlled study of diet in patients with gout. Ann Rheum Dis 1983 : 42,123-127. – reference: 2) Hiyamuta, K et al. Relationship between coro nary risk factor and arteriographic feature of coronary atherosclerosis. Jpn Circ J 1990 ; 54 : 442-447. – reference: 10) Hall, A. P., et al. Epidemiology of gout and hyperuricemia. Am. J. Med. 1967 : 42 : 27-37. – reference: 11) Lieber, C. S., et al. Interrelation of uric acid and ethanol metabolism in man. J. Clin. Invest. 1962 : 41 : 1863-1870. – reference: 12) Faller, J., Fox, I. H. Ethanol-induced hyperuricemia. Evidence for increased urate production by activation of adenine nucleotide turnover. N Engl J Med 1982 : 307 : 1598-1602. – reference: 3) 香川 綾, 監修.四訂食品成分表.科学技術庁資源調査会編.女子栄養大学出版部, 1986; 226-235. – reference: 4) 金井 泉, 金井正光.臨床検査法提要.金原出版株式会社, 1983; 432-436. – reference: 1) 西岡久寿樹.高尿酸血症.循環科学.丸善株式会社, 1992 ; 12 : 34-37. – reference: 14) 藤森 新, 他. アルコール飲料中のプリン体含有量, 尿酸, 1985 : 9,128-133. – reference: 5) 緒方尚子.臨床栄養学提要・実習.医歯薬出版株式会社, 1988; 81-83. |
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| SubjectTerms | drinking habits field survey hemoglobin A1c (HbA1c) hyperuricemia obesity ヘモグロビンA1c 地域集団 肥満 飲酒 高尿酸血症 |
| Subtitle | Filed Survey Examination |
| Title | Factors related to hyperuricemia |
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