A clinical study of before and after stroke-like episodes in MELAS syndrome

Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS) is the most representative subtype of mitochondrial diseases. However, the pathogenesis of the stroke-like episodes remains unknown. We experienced a patient with MELAS and her first stroke-like episod...

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Bibliographic Details
Published injibi to rinsho Vol. 62; no. 6; pp. 225 - 233
Main Authors YOSHIKAWA, Satoko, MATSUOKA, Rina, IKEDA, Katsuhisa, HIBIYA, Remi
Format Journal Article
LanguageJapanese
Published JIBI TO RINSHO KAI 20.11.2016
耳鼻と臨床会
Subjects
MELAS
ミトコンドリア脳筋症
中等度難聴
脳卒中様発作
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ISSN0447-7227
2185-1034
DOI10.11334/jibi.62.6_225

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Summary:Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes syndrome (MELAS) is the most representative subtype of mitochondrial diseases. However, the pathogenesis of the stroke-like episodes remains unknown. We experienced a patient with MELAS and her first stroke-like episode with a lesion in the left temporal lobe at 31 years of age. Our data indicated that hearing thresholds did not change before and after the stroke-like episode；however, her hearing level for speech in the right ear declined markedly the day before the stroke-like episode. We suspect that the decline in the hearing level for speech might be related to the symptom of the stroke-like episodes.
ISSN:0447-7227
2185-1034
DOI:10.11334/jibi.62.6_225