Fournier gangrene

Fournier gangrene (FG) is defined as necrotizing fasciitis that progresses rapidly, mainly in the genital, perineum, and perianal areas, and has a high mortality rate. Therefore, it is important to immediately assess the disease severity and initiate appropriate treatment. We report a case of FG in...

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Published inJournal of the Japan Organization of Clinical Dermatologists Vol. 42; no. 1; pp. 48 - 52
Main Author Niiyasu, Shoya
Format Journal Article
LanguageJapanese
Published Japan Organization of Clinical Dermatologists 2025
日本臨床皮膚科医会
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ISSN1349-7758
1882-272X
DOI10.3812/jocd.42.48

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Abstract Fournier gangrene (FG) is defined as necrotizing fasciitis that progresses rapidly, mainly in the genital, perineum, and perianal areas, and has a high mortality rate. Therefore, it is important to immediately assess the disease severity and initiate appropriate treatment. We report a case of FG in which indices, such as the Uludag FG severity index (UFGSI) and simplified FGSI (SFGSI), were low. Appropriate treatment was administered, and the patient did not develop severe disease.The patient was a 59-year-old man who has been suffering from buttock pain for eight days. Oral antibiotic treatment was initiated at a local hospital; however, there was no improvement. He had difficulty walking; therefore, he was referred to our department. Erythema and fluctuating motions were observed on the right scrotum and left buttock, and a snow-grabbing sensation was palpable in the right scrotum. Contrast-enhanced computed tomography revealed gas and liquid accumulation with a clear border around the perineum; hence, FG was diagnosed. The LRINEC score was 8, and necrotizing fasciitis was considered; however, the UFGSI was 7 and SFGSI was 0, indicating a low-risk assessment. Streptococcus constellatus and Prevotella bivia were detected in the necrotic tissue cultures. Incision, drainage, and debridement were performed, and the affected area and overall condition rapidly improved.FGSI and UFGSI are useful for assessing the risk of FG. As these scores are difficult to calculate, a simplified version of the SFGSI has been devised and reported to be a useful index. Early diagnosis and treatment of FG are extremely important. We believe that indices that predict disease progression, such as the UFGSI and SFGSI, are useful.
AbstractList Fournier gangrene (FG) is defined as necrotizing fasciitis that progresses rapidly, mainly in the genital, perineum, and perianal areas, and has a high mortality rate. Therefore, it is important to immediately assess the disease severity and initiate appropriate treatment. We report a case of FG in which indices, such as the Uludag FG severity index (UFGSI) and simplified FGSI (SFGSI), were low. Appropriate treatment was administered, and the patient did not develop severe disease. The patient was a 59-year-old man who has been suffering from buttock pain for eight days. Oral antibiotic treatment was initiated at a local hospital; however, there was no improvement. He had difficulty walking; therefore, he was referred to our department. Erythema and fluctuating motions were observed on the right scrotum and left buttock, and a snow-grabbing sensation was palpable in the right scrotum. Contrast-enhanced computed tomography revealed gas and liquid accumulation with a clear border around the perineum; hence, FG was diagnosed. The LRINEC score was 8, and necrotizing fasciitis was considered; however, the UFGSI was 7 and SFGSI was 0, indicating a low-risk assessment. Streptococcus constellatus and Prevotella bivia were detected in the necrotic tissue cultures. Incision, drainage, and debridement were performed, and the affected area and overall condition rapidly improved. FGSI and UFGSI are useful for assessing the risk of FG. As these scores are difficult to calculate, a simplified version of the SFGSI has been devised and reported to be a useful index. Early diagnosis and treatment of FG are extremely important. We believe that indices that predict disease progression, such as the UFGSI and SFGSI, are useful. フルニエ壊疽は生殖器,会陰部,肛門周囲を中心として急速に進行する壊死性筋膜炎と定義されており,死亡率が高い疾患であるため,迅速な重症度評価を行い,適切な治療をできるだけ早期に開始することが重要である.今回,UFGSやSFGSIといった指標が低値であり,適切な治療を行ったことで重症化しなかったフルニエ壊疽の一例を経験したため,考察を加えて報告する.  症例は高血圧以外の既往がない59歳の男性.8日前から臀部痛があり,近医にて抗菌薬の内服治療が開始されたが改善なく,歩行困難となったため当科受診された.当科受診時,右陰嚢,左臀部に紅斑を認め,右陰嚢部に波動および握雪感を触れた.陰茎の腫脹,睾丸把握痛は認めなかった.造影CT検査にて陰茎腹側から会陰部周囲に境界明瞭なガス像および液体貯留を,左会陰部から左臀部に脂肪組織濃度の上昇を認め,フルニエ壊疽と診断した.陰嚢,陰茎,睾丸周囲は辺縁が保たれていた.直腸周囲に腫瘤性病変は指摘できなかった. LRINECスコア(Laboratory risk indicator for necrotizing fasciitis score)8点と壊死性筋膜炎が考慮されたが,UFGSIは7点,SFGSIは0点と低リスクの評価であった.血液培養検査は陰性であったが,壊死組織の培養からはStreptococcus constellatus ssp pharynge,Prevotella biviaが検出された.同日,切開ドレナージおよびデブリードマンを施行し,抗菌薬投与を行い,患部と全身状態は速やかに改善した.  フルニエ壊疽のリスク評価には,FGSIやUFGSIが有用である.それらのスコアは計算が煩雑であるため,簡略化されたSFGSIも考案されており,有用な指標であるとの報告もされている.フルニエ壊疽は早期の診断と処置が大変重要であるが,UFGSI,SFGSIといった重症化を予測する指標は参考になると考えた.
Fournier gangrene (FG) is defined as necrotizing fasciitis that progresses rapidly, mainly in the genital, perineum, and perianal areas, and has a high mortality rate. Therefore, it is important to immediately assess the disease severity and initiate appropriate treatment. We report a case of FG in which indices, such as the Uludag FG severity index (UFGSI) and simplified FGSI (SFGSI), were low. Appropriate treatment was administered, and the patient did not develop severe disease.The patient was a 59-year-old man who has been suffering from buttock pain for eight days. Oral antibiotic treatment was initiated at a local hospital; however, there was no improvement. He had difficulty walking; therefore, he was referred to our department. Erythema and fluctuating motions were observed on the right scrotum and left buttock, and a snow-grabbing sensation was palpable in the right scrotum. Contrast-enhanced computed tomography revealed gas and liquid accumulation with a clear border around the perineum; hence, FG was diagnosed. The LRINEC score was 8, and necrotizing fasciitis was considered; however, the UFGSI was 7 and SFGSI was 0, indicating a low-risk assessment. Streptococcus constellatus and Prevotella bivia were detected in the necrotic tissue cultures. Incision, drainage, and debridement were performed, and the affected area and overall condition rapidly improved.FGSI and UFGSI are useful for assessing the risk of FG. As these scores are difficult to calculate, a simplified version of the SFGSI has been devised and reported to be a useful index. Early diagnosis and treatment of FG are extremely important. We believe that indices that predict disease progression, such as the UFGSI and SFGSI, are useful.
Author Niiyasu, Shoya
Author_FL 新安 祥也
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Carlos Eugênio Lira Tenório et al:Risk factors for mortality in fournier's gangrene in a general hospital: use of simplified founier gangrene severe index score (SFGSI). Int Braz J Urol 2018; 44: 95-101.
Shannon MF et al:Necrotizing Soft Tissue Infection: Diagnostic Accuracy of Physical Examination, Imaging, and LRINEC Score: A Systematic Review and Meta-Analysis. Ann Surg 2019; 269: 58-65.
Tsung YL et al:Validation and simplification of Fournier's gangrene severity index. Int J Urol 2014; 21: 696-701.
坂本昭彦ほか:フルニエ壊疽15例の臨床的検討.日泌尿会誌 2021; 112: 65-69.
J A Fournier: Gangrène foudroyante de la verge (overwhelming gangrene),Dis Colon Rectum 1998; 31, 984-988.
野田昌宏ほか:フルニエ壊疽の重症度評価と治療法に関する検討.日腹部救急医会誌 2014; 34: 1107-1112.
Loar E et al:Outcome prediction in patients with Fournier’s gangrene. J Urol 1995; 154: 89-92.
T Yilmazlar et al:Fournier's gangrene: an analysis of 80 patients and a novel scoring system. Tech Coloproctol 2010; 14: 217-223.
References_xml – reference: Tsung YL et al:Validation and simplification of Fournier's gangrene severity index. Int J Urol 2014; 21: 696-701.
– reference: Loar E et al:Outcome prediction in patients with Fournier’s gangrene. J Urol 1995; 154: 89-92.
– reference: J A Fournier: Gangrène foudroyante de la verge (overwhelming gangrene),Dis Colon Rectum 1998; 31, 984-988.
– reference: 坂本昭彦ほか:フルニエ壊疽15例の臨床的検討.日泌尿会誌 2021; 112: 65-69.
– reference: 野田昌宏ほか:フルニエ壊疽の重症度評価と治療法に関する検討.日腹部救急医会誌 2014; 34: 1107-1112.
– reference: N Eke:Fournier's gangrene: a review of 1726 cases.Br J Surg 2000; 87: 718-728.
– reference: Shannon MF et al:Necrotizing Soft Tissue Infection: Diagnostic Accuracy of Physical Examination, Imaging, and LRINEC Score: A Systematic Review and Meta-Analysis. Ann Surg 2019; 269: 58-65.
– reference: T Yilmazlar et al:Fournier's gangrene: an analysis of 80 patients and a novel scoring system. Tech Coloproctol 2010; 14: 217-223.
– reference: Carlos Eugênio Lira Tenório et al:Risk factors for mortality in fournier's gangrene in a general hospital: use of simplified founier gangrene severe index score (SFGSI). Int Braz J Urol 2018; 44: 95-101.
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Snippet Fournier gangrene (FG) is defined as necrotizing fasciitis that progresses rapidly, mainly in the genital, perineum, and perianal areas, and has a high...
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SubjectTerms Fournier gangrene
Laboratory risk indicator for necrotizing fasciitis score
LRINECスコア
necrotizing fasciitis
SFGSI
simplified FGSI
UFGSI
uludag Fournierʼs gangrene severity index
フルニエ壊疽
壊死性筋膜炎
Title Fournier gangrene
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