ヒト肺亜細葉4Dモデルによる肺拡散能シミュレーション

I have constructed a 4D subacinar model which contains the capillary space in the alveolar wall (Figure). Oxygen transport is computed by the use of computational fluid dynamics in which incompressive Navier-Stokes equation and the diffusion equation are directly coupled. Simulated results indicated...

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Published inTransactions of Japanese Society for Medical and Biological Engineering Vol. 54Annual; no. 26PM-Abstract; p. S99
Main Author 北岡, 裕子
Format Journal Article
LanguageJapanese
Published 公益社団法人 日本生体医工学会 2016
Japanese Society for Medical and Biological Engineering
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ISSN1347-443X
1881-4379
DOI10.11239/jsmbe.54Annual.S99

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Summary:I have constructed a 4D subacinar model which contains the capillary space in the alveolar wall (Figure). Oxygen transport is computed by the use of computational fluid dynamics in which incompressive Navier-Stokes equation and the diffusion equation are directly coupled. Simulated results indicated that the blood oxygen partial pressure was little influenced by the alveolar wall thickness but highly dependent of the effective blood flow rate. This simulation study will be useful for investigating respiratory pathophysiology and for developing an implantable artificial lung.
ISSN:1347-443X
1881-4379
DOI:10.11239/jsmbe.54Annual.S99