リンパ行性転移と考えられる前立腺癌直腸転移の1例
症例は53歳の男性で,便秘,腰背部痛を主訴に当院を受診した.下部消化管内視鏡検査で下部直腸に全周性の病変を認めた.同部位の生検組織から低分化腺癌が確認された.また,血清PSA値が高値であり,前立腺生検を施行したところGleason score 9点で,前立腺癌の診断となった.CT,PET-CTより硬化性の転移性骨腫瘍の所見は認めたが,前立腺と直腸の間は比較的明瞭であり,前立腺癌骨転移と原発性直腸癌の併存と診断した.原発性直腸癌に対して腹腔鏡下Hartmann手術を施行した.病理組織検査では上皮性の異型は乏しく,粘膜下から漿膜側を主体に低分化腺癌の浸潤増殖を認め,リンパ管内にも腫瘍細胞の充満を認...
Saved in:
Published in | 日本臨床外科学会雑誌 Vol. 82; no. 6; pp. 1172 - 1179 |
---|---|
Main Authors | , , , , , , |
Format | Journal Article |
Language | Japanese |
Published |
日本臨床外科学会
2021
|
Subjects | |
Online Access | Get full text |
ISSN | 1345-2843 1882-5133 |
DOI | 10.3919/jjsa.82.1172 |
Cover
Abstract | 症例は53歳の男性で,便秘,腰背部痛を主訴に当院を受診した.下部消化管内視鏡検査で下部直腸に全周性の病変を認めた.同部位の生検組織から低分化腺癌が確認された.また,血清PSA値が高値であり,前立腺生検を施行したところGleason score 9点で,前立腺癌の診断となった.CT,PET-CTより硬化性の転移性骨腫瘍の所見は認めたが,前立腺と直腸の間は比較的明瞭であり,前立腺癌骨転移と原発性直腸癌の併存と診断した.原発性直腸癌に対して腹腔鏡下Hartmann手術を施行した.病理組織検査では上皮性の異型は乏しく,粘膜下から漿膜側を主体に低分化腺癌の浸潤増殖を認め,リンパ管内にも腫瘍細胞の充満を認めた.腫瘍細胞はPSA染色,NKX3.1染色で陽性であった.以上からリンパ行性による前立腺癌直腸転移と診断した. |
---|---|
AbstractList | 症例は53歳の男性で,便秘,腰背部痛を主訴に当院を受診した.下部消化管内視鏡検査で下部直腸に全周性の病変を認めた.同部位の生検組織から低分化腺癌が確認された.また,血清PSA値が高値であり,前立腺生検を施行したところGleason score 9点で,前立腺癌の診断となった.CT,PET-CTより硬化性の転移性骨腫瘍の所見は認めたが,前立腺と直腸の間は比較的明瞭であり,前立腺癌骨転移と原発性直腸癌の併存と診断した.原発性直腸癌に対して腹腔鏡下Hartmann手術を施行した.病理組織検査では上皮性の異型は乏しく,粘膜下から漿膜側を主体に低分化腺癌の浸潤増殖を認め,リンパ管内にも腫瘍細胞の充満を認めた.腫瘍細胞はPSA染色,NKX3.1染色で陽性であった.以上からリンパ行性による前立腺癌直腸転移と診断した. |
Author | 飛永, 修一 駒木, 倫比古 重松, 和人 野田, 恵佑 中崎, 隆行 谷口, 英樹 柴田, 良仁 |
Author_xml | – sequence: 1 fullname: 野田, 恵佑 organization: 日本赤十字社長崎原爆病院外科 – sequence: 1 fullname: 駒木, 倫比古 organization: 日本赤十字社長崎原爆病院外科 – sequence: 1 fullname: 中崎, 隆行 organization: 日本赤十字社長崎原爆病院外科 – sequence: 1 fullname: 飛永, 修一 organization: 日本赤十字社長崎原爆病院外科 – sequence: 1 fullname: 柴田, 良仁 organization: 日本赤十字社長崎原爆病院外科 – sequence: 1 fullname: 谷口, 英樹 organization: 日本赤十字社長崎原爆病院外科 – sequence: 1 fullname: 重松, 和人 organization: 日本赤十字社長崎原爆病院病理診断科 |
BookMark | eNo9UD1Lw0AAPaSCtXbzbyTeR-5ymUSKVaHgonO4XC6aUKskXdzahIIlcXAUJ10qCi46iAX_zKnJz7DBjze89-A93vBWQWNwOlAArCNoEgc5G1GUCJNjEyEbL4Em4hwbFBHSWHhiUQNzi6yAdpKEHoR4AQppE3R19qCzZ51dVbfF12hWze_K2VyP76tRpscXOp3qtNBp_jm9LB_zavJWXhflzUs1ef1rPqGP93wNLAein6j2r7bAYXf7oLNr9PZ39jpbPSPCNmYG9yCHTHq-L2yOYSC5kgLZiiFP-oxLgn2CAkwsRBniijPiU-mQgFLPVg62SAts_uxGyVAcKfcsDk9EfO6KeBjKvnLrE1yOXVZT_cR_Io9F7EaCfAOjRnDE |
ContentType | Journal Article |
Copyright | 2021 日本臨床外科学会 |
Copyright_xml | – notice: 2021 日本臨床外科学会 |
DOI | 10.3919/jjsa.82.1172 |
DatabaseTitleList | |
DeliveryMethod | fulltext_linktorsrc |
EISSN | 1882-5133 |
EndPage | 1179 |
ExternalDocumentID | article_jjsa_82_6_82_1172_article_char_ja |
GroupedDBID | 123 2WC ALMA_UNASSIGNED_HOLDINGS CS3 JSF KQ8 RJT |
ID | FETCH-LOGICAL-j2726-8b0806cbdda7820fc8eca17e61bcd68c32d31f23415618e863d5c93f55b7e9243 |
ISSN | 1345-2843 |
IngestDate | Wed Sep 03 06:31:04 EDT 2025 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | true |
Issue | 6 |
Language | Japanese |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-j2726-8b0806cbdda7820fc8eca17e61bcd68c32d31f23415618e863d5c93f55b7e9243 |
OpenAccessLink | https://www.jstage.jst.go.jp/article/jjsa/82/6/82_1172/_article/-char/ja |
PageCount | 8 |
ParticipantIDs | jstage_primary_article_jjsa_82_6_82_1172_article_char_ja |
PublicationCentury | 2000 |
PublicationDate | 20210000 |
PublicationDateYYYYMMDD | 2021-01-01 |
PublicationDate_xml | – year: 2021 text: 20210000 |
PublicationDecade | 2020 |
PublicationTitle | 日本臨床外科学会雑誌 |
PublicationTitleAlternate | 日臨外会誌 |
PublicationYear | 2021 |
Publisher | 日本臨床外科学会 |
Publisher_xml | – name: 日本臨床外科学会 |
References | 14) 吉田暁正, 太田智之, 鈴木晶子他:直腸粘膜下腫瘍の形態を呈した前立腺癌直腸壁転移の1例.旭川厚生病医誌 1998;8:129-134 20) 多久和晴子, 竹本研史, 横尾直樹他:直腸粘膜下転移を来した前立腺導管癌の1例.日消外会誌 2009;42:322-327 10) 今村誠子, 島岡俊治, 田代光太郎他:全周性直腸浸潤をきたした前立腺癌の2例.日消誌 2012;109:425-434 2) Winter CC : Prostatic carcinoma involving the rectum ; the problem of differentiation from other malignant lesions. Calif Med 1955 ; 82 : 85-90 23) Abbas TO, Al-Naimi AR, Yakoob RA, et al : Prostate cancer metastases to the rectum : a case report. World J Surg Oncol 2011 ; 9 : 56 26) Dulskas A, Cereska V, Zurauskas E, et al : Prostate cancer solitary metastasis to anal canal : case report and review of literature. BMC Cancer 2019 ; 19 : 374 3) Gengler L, Baer J, Finby N : Rectal and sigmoid involvement secondary to carcinoma of the prostate. Am J Roentgenol Radium Ther Nucl Med 1975 ; 125 : 910-917 7) Catalona WJ, Richie JP, Ahmann FR, et al : Comparison of digital rectal examination and serum prostate specific antigen in the early detection of prostate cancer : results of a multicenter clinical trial of 6,630 men. J Urol 1994 ; 151 : 1283-1290 15) Suzuki Y, Oishi Y, Yamazaki H, et al : Recurrent prostatic carcinoma metastatic to the rectum mimicking rectal carcinoma. Jikeikai Med J 2001 ; 48 : 47-52 19) 藤田孝義, 榊原真肇, 側島 友他:大腸への転移病変から診断された前立腺癌の1例.Gastroenterol Endosc 2009;51:2897-2904 8) Rana A, Karamanis K, Lucas MG, et al : Identification of metastatic disease by T category, gleason score and serum PSA level in patients with carcinoma of the prostate. Br J Urol 1992 ; 69 : 277-281 1) Lasser A : Adenocarcinoma of the prostate involving the rectum. Dis Colon Rectum 1978 ; 21 : 23-25 17) 木内 誠, 椎葉健一, 佐藤 学他:直腸癌との鑑別が困難であった前立腺癌直腸転移の1例.日消外会誌 2005;38:1844-1849 25) Liu ZH, Li C, Kang L, et al : Prostate cancer incorrectly diagnosed as a rectal tumor : a case report. Oncol Lett 2015 ; 9 : 2647-2650 21) 宇野雄祐, 小谷勝祥, 松山孝昭他:前立腺癌直腸転移の1例.日臨外会誌 2010;71:1828-1831 12) Chuang AY, DeMarzo AM, Veltri RW, et al : Immunohistochemical differentiation of high-grade prostate carcinoma from urothelial carcinoma. Am J Surg Pathol 2007 ; 31 : 1246-1255 11) Culkin DJ, Demos TC, Wheeler JS, et al : Separate annular strictures of the rectosigmoid colon secondary to unsuspected prostate cancer. J Surg Oncol 1990 ; 43 : 189-192 18) Vaghefi H, Magi-Galluzzi C, Klein EA : Local recurrence of prostate cancer in rectal submucosa after transrectal needle biopsy and radical prostatectomy. Urology 2005 ; 66 : 881 6) 柳田俊彦, 蓮井良浩, 上原和隆他:直腸浸潤を示した前立腺癌の臨床的検討.西日泌 1993;55:1419-1423 13) 森田照男, 目黒則男, 友岡義夫他:前立腺癌の直腸転移により直腸輪状狭窄をきたした1例.泌紀 1991;37:295-298 16) 大仁田亨, 今里祐之, 正野武文他:直腸転移をきたした前立腺癌の1例.西日泌 2005;67:607-610 24) Nwankwo N, Mirrakhimov AE, Zdunek T, et al : Prostate adenocarcinoma with a rectal metastasis. BMJ Case Rep 2013 ; 30 : bcr2013009503 5) Bowrey DJ, Otter MI, Billings PJ : Rectal infiltration by prostatic adenocarcinoma : report on six patients and review of the literature. Ann R Coll Surg Engl 2003 ; 85 : 382-385 22) Venara A, Thibaudeau E, Lebdai S, et al : Rectal metastasis of prostate cancer : about a case. J Clin Med Res 2010 ; 2 : 137-139 9) Lane Z, Epstein JI, Ayub S, et al : Prostatic adenocarcinoma in colorectal biopsy : clinical and pathologic features. Hum Pathol 2008 ; 39 : 543-549 4) Murray SK, Breau RH, Guha AK, et al : Spread of prostate carcinoma to the perirectal lymph node basin : analysis of 112 rectal resections over 10-year span for primary rectal adenocarcinoma. Am J Surg Pathol 2004 ; 28 : 1154-1162 |
References_xml | – reference: 19) 藤田孝義, 榊原真肇, 側島 友他:大腸への転移病変から診断された前立腺癌の1例.Gastroenterol Endosc 2009;51:2897-2904 – reference: 5) Bowrey DJ, Otter MI, Billings PJ : Rectal infiltration by prostatic adenocarcinoma : report on six patients and review of the literature. Ann R Coll Surg Engl 2003 ; 85 : 382-385 – reference: 15) Suzuki Y, Oishi Y, Yamazaki H, et al : Recurrent prostatic carcinoma metastatic to the rectum mimicking rectal carcinoma. Jikeikai Med J 2001 ; 48 : 47-52 – reference: 20) 多久和晴子, 竹本研史, 横尾直樹他:直腸粘膜下転移を来した前立腺導管癌の1例.日消外会誌 2009;42:322-327 – reference: 11) Culkin DJ, Demos TC, Wheeler JS, et al : Separate annular strictures of the rectosigmoid colon secondary to unsuspected prostate cancer. J Surg Oncol 1990 ; 43 : 189-192 – reference: 17) 木内 誠, 椎葉健一, 佐藤 学他:直腸癌との鑑別が困難であった前立腺癌直腸転移の1例.日消外会誌 2005;38:1844-1849 – reference: 14) 吉田暁正, 太田智之, 鈴木晶子他:直腸粘膜下腫瘍の形態を呈した前立腺癌直腸壁転移の1例.旭川厚生病医誌 1998;8:129-134 – reference: 4) Murray SK, Breau RH, Guha AK, et al : Spread of prostate carcinoma to the perirectal lymph node basin : analysis of 112 rectal resections over 10-year span for primary rectal adenocarcinoma. Am J Surg Pathol 2004 ; 28 : 1154-1162 – reference: 18) Vaghefi H, Magi-Galluzzi C, Klein EA : Local recurrence of prostate cancer in rectal submucosa after transrectal needle biopsy and radical prostatectomy. Urology 2005 ; 66 : 881 – reference: 1) Lasser A : Adenocarcinoma of the prostate involving the rectum. Dis Colon Rectum 1978 ; 21 : 23-25 – reference: 8) Rana A, Karamanis K, Lucas MG, et al : Identification of metastatic disease by T category, gleason score and serum PSA level in patients with carcinoma of the prostate. Br J Urol 1992 ; 69 : 277-281 – reference: 26) Dulskas A, Cereska V, Zurauskas E, et al : Prostate cancer solitary metastasis to anal canal : case report and review of literature. BMC Cancer 2019 ; 19 : 374 – reference: 9) Lane Z, Epstein JI, Ayub S, et al : Prostatic adenocarcinoma in colorectal biopsy : clinical and pathologic features. Hum Pathol 2008 ; 39 : 543-549 – reference: 10) 今村誠子, 島岡俊治, 田代光太郎他:全周性直腸浸潤をきたした前立腺癌の2例.日消誌 2012;109:425-434 – reference: 6) 柳田俊彦, 蓮井良浩, 上原和隆他:直腸浸潤を示した前立腺癌の臨床的検討.西日泌 1993;55:1419-1423 – reference: 12) Chuang AY, DeMarzo AM, Veltri RW, et al : Immunohistochemical differentiation of high-grade prostate carcinoma from urothelial carcinoma. Am J Surg Pathol 2007 ; 31 : 1246-1255 – reference: 7) Catalona WJ, Richie JP, Ahmann FR, et al : Comparison of digital rectal examination and serum prostate specific antigen in the early detection of prostate cancer : results of a multicenter clinical trial of 6,630 men. J Urol 1994 ; 151 : 1283-1290 – reference: 24) Nwankwo N, Mirrakhimov AE, Zdunek T, et al : Prostate adenocarcinoma with a rectal metastasis. BMJ Case Rep 2013 ; 30 : bcr2013009503 – reference: 2) Winter CC : Prostatic carcinoma involving the rectum ; the problem of differentiation from other malignant lesions. Calif Med 1955 ; 82 : 85-90 – reference: 22) Venara A, Thibaudeau E, Lebdai S, et al : Rectal metastasis of prostate cancer : about a case. J Clin Med Res 2010 ; 2 : 137-139 – reference: 23) Abbas TO, Al-Naimi AR, Yakoob RA, et al : Prostate cancer metastases to the rectum : a case report. World J Surg Oncol 2011 ; 9 : 56 – reference: 21) 宇野雄祐, 小谷勝祥, 松山孝昭他:前立腺癌直腸転移の1例.日臨外会誌 2010;71:1828-1831 – reference: 25) Liu ZH, Li C, Kang L, et al : Prostate cancer incorrectly diagnosed as a rectal tumor : a case report. Oncol Lett 2015 ; 9 : 2647-2650 – reference: 3) Gengler L, Baer J, Finby N : Rectal and sigmoid involvement secondary to carcinoma of the prostate. Am J Roentgenol Radium Ther Nucl Med 1975 ; 125 : 910-917 – reference: 16) 大仁田亨, 今里祐之, 正野武文他:直腸転移をきたした前立腺癌の1例.西日泌 2005;67:607-610 – reference: 13) 森田照男, 目黒則男, 友岡義夫他:前立腺癌の直腸転移により直腸輪状狭窄をきたした1例.泌紀 1991;37:295-298 |
SSID | ssib002222505 ssib029852155 ssib039893138 ssib043658141 ssib058493876 ssj0061900 ssib000940327 ssib002822084 ssib002484630 ssib002484631 |
Score | 2.2532551 |
Snippet | 症例は53歳の男性で,便秘,腰背部痛を主訴に当院を受診した.下部消化管内視鏡検査で下部直腸に全周性の病変を認めた.同部位の生検組織から低分化腺癌が確... |
SourceID | jstage |
SourceType | Publisher |
StartPage | 1172 |
SubjectTerms | NKX3.1 前立腺癌 転移性直腸腫瘍 |
Title | リンパ行性転移と考えられる前立腺癌直腸転移の1例 |
URI | https://www.jstage.jst.go.jp/article/jjsa/82/6/82_1172/_article/-char/ja |
Volume | 82 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
ispartofPNX | 日本臨床外科学会雑誌, 2021, Vol.82(6), pp.1172-1179 |
journalDatabaseRights | – providerCode: PRVAFT databaseName: Open Access Digital Library customDbUrl: eissn: 1882-5133 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0061900 issn: 1345-2843 databaseCode: KQ8 dateStart: 19980101 isFulltext: true titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html providerName: Colorado Alliance of Research Libraries |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3Na9VAEA-1XryIouI3PbjH1Lcf2cwek9c8iqAgtNDb422Sd3iHKtpeemr7KFhaDx7Fk14qCl70IBb8Z6K-d_NfcGaTNClUqMVLmExmZyczCfubZWfX8-7hGD3Ez5b7QoS5r3Lg_iALEMilKrAdnUkBVOD88JFeXFYPVoKVmXO_W6uW1tfsfLpxYl3JWaKKPIwrVcn-Q2SPlCIDaYwvXjHCeD1VjFkiGUgWRRURy4ownCXAIs6gyxJNqxmikDhxzCLBkpBukSZhziKgRygDsuIAOEIwMDXRrQlsFRAfFpye2HGwecDiiDjGOGEkYhar-hH8vfcEbVUsTlBRGymT3QZFA0d0WdR1ukJnrusMIiIixYyulNJrI2eBRdrp7DKDMoZMqTyCrY6mhekJ6oPEWYviHfrenL84iwOnYYEZ3panTkRtEZTygfNvTNyoR4qI00PDmoaKPIB2keGKenQNDZkH-ihUxzqSZDWqRKviqiPUgmqTSl15NFU9YyOauZr_5bnWeCVV4CPCKMeIvORR0kTH9rQHORCtn7k9YnFeHp1UoR_aIfCkkVUaThvTjkbPB_Mg5ptWx_Yqr_6EPon1QfQ1XUi2Xz-hWsL-CBOa8yJEaEirKB638gGjOlK05xcEQfQWnkS43Mp3y_tjhdii0xReCwOITpvCa2kQnfNmwFES8Tdv8gEE40YC4fMSymlEy-U2A5WXy8oZ8sX9ticQvY4wl6vXgTpounTJu1jllHNR-fKXvZnR4IrXK8YfivHnYvxq-nb_1-bB9PDd5OCw2Ho_3RwXWy-K7d1ie7_Y3vu5-3LycW-6823yen_y5st052st-Yn_-L531VvuJUvdRb86NMUfiVBoHyzmgDq1WTagrTCHKeTpgIe55jbNNKRSZJIPhaSJGw45aJkFqZHDILBhboSS17zZ1Ser-XVvzppAgFWpkKFSqVVW20Gehzy0GUIBYW94UL52_2m5M07_1PG_efamt7wL9FOV06C3vdm1Z-v5HUwM1uxd9zH9AWGD0fY |
linkProvider | Colorado Alliance of Research Libraries |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E3%83%AA%E3%83%B3%E3%83%91%E8%A1%8C%E6%80%A7%E8%BB%A2%E7%A7%BB%E3%81%A8%E8%80%83%E3%81%88%E3%82%89%E3%82%8C%E3%82%8B%E5%89%8D%E7%AB%8B%E8%85%BA%E7%99%8C%E7%9B%B4%E8%85%B8%E8%BB%A2%E7%A7%BB%E3%81%AE1%E4%BE%8B&rft.jtitle=%E6%97%A5%E6%9C%AC%E8%87%A8%E5%BA%8A%E5%A4%96%E7%A7%91%E5%AD%A6%E4%BC%9A%E9%9B%91%E8%AA%8C&rft.au=%E9%87%8E%E7%94%B0%2C+%E6%81%B5%E4%BD%91&rft.au=%E9%A7%92%E6%9C%A8%2C+%E5%80%AB%E6%AF%94%E5%8F%A4&rft.au=%E4%B8%AD%E5%B4%8E%2C+%E9%9A%86%E8%A1%8C&rft.au=%E9%A3%9B%E6%B0%B8%2C+%E4%BF%AE%E4%B8%80&rft.date=2021&rft.pub=%E6%97%A5%E6%9C%AC%E8%87%A8%E5%BA%8A%E5%A4%96%E7%A7%91%E5%AD%A6%E4%BC%9A&rft.issn=1345-2843&rft.eissn=1882-5133&rft.volume=82&rft.issue=6&rft.spage=1172&rft.epage=1179&rft_id=info:doi/10.3919%2Fjjsa.82.1172&rft.externalDocID=article_jjsa_82_6_82_1172_article_char_ja |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1345-2843&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1345-2843&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1345-2843&client=summon |