COVID–19と認知症診療
「はじめに」重症急性呼吸器症候群コロナウイルス2(Severe Acute Respiratory Syndrome Coronavirus 2:SARS-CoV-2)のパンデミックにおいて, 本稿を執筆している2020年10月4日時点で世界全体の累計感染者は3480万人に, 死亡者は103万人に達している. 加齢, 慢性閉塞性肺疾患, がん, 重篤な心疾患, 糖尿病などはSARS-CoV-2によって引き起こされるコロナウイルス疾患2019(Coronavirus Disease 2019:COVID-19)の重症化リスクであるが, 認知症患者も重症化リスクと死亡率が高いことが報告されている....
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| Published in | 神経治療学 Vol. 38; no. 1; pp. 24 - 27 |
|---|---|
| Main Authors | , |
| Format | Journal Article |
| Language | Japanese |
| Published |
日本神経治療学会
2021
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0916-8443 2189-7824 |
| DOI | 10.15082/jsnt.38.1_24 |
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| Abstract | 「はじめに」重症急性呼吸器症候群コロナウイルス2(Severe Acute Respiratory Syndrome Coronavirus 2:SARS-CoV-2)のパンデミックにおいて, 本稿を執筆している2020年10月4日時点で世界全体の累計感染者は3480万人に, 死亡者は103万人に達している. 加齢, 慢性閉塞性肺疾患, がん, 重篤な心疾患, 糖尿病などはSARS-CoV-2によって引き起こされるコロナウイルス疾患2019(Coronavirus Disease 2019:COVID-19)の重症化リスクであるが, 認知症患者も重症化リスクと死亡率が高いことが報告されている. 上述のCOVID-19の重症化リスクの疾患が併存している認知症患者は特に重症化しやすく, より重度の認知症患者で死亡リスクが高いことが報告されている. 認知症患者がCOVID-19に罹患した場合の臨床像を認識しておくことは, 発症早期にCOVID-19を疑って適格な診断治療へと進めていく上で重要である. |
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| AbstractList | 「はじめに」重症急性呼吸器症候群コロナウイルス2(Severe Acute Respiratory Syndrome Coronavirus 2:SARS-CoV-2)のパンデミックにおいて, 本稿を執筆している2020年10月4日時点で世界全体の累計感染者は3480万人に, 死亡者は103万人に達している. 加齢, 慢性閉塞性肺疾患, がん, 重篤な心疾患, 糖尿病などはSARS-CoV-2によって引き起こされるコロナウイルス疾患2019(Coronavirus Disease 2019:COVID-19)の重症化リスクであるが, 認知症患者も重症化リスクと死亡率が高いことが報告されている. 上述のCOVID-19の重症化リスクの疾患が併存している認知症患者は特に重症化しやすく, より重度の認知症患者で死亡リスクが高いことが報告されている. 認知症患者がCOVID-19に罹患した場合の臨床像を認識しておくことは, 発症早期にCOVID-19を疑って適格な診断治療へと進めていく上で重要である. |
| Author | 伊井, 裕一郎 冨本, 秀和 |
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| DOI | 10.15082/jsnt.38.1_24 |
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| References | 3) Wan Y, Wu J, Lihua Ni L et al : Prognosis analysis of patients with mental disorders with COVID–19 : a single–center retrospective study. Aging (Albany NY) 12 : 11238–11244, 2020 25) Heneka MT, Golenbock D, Latz E et al : Immediate and long–term consequences of COVID–19 infections for the development of neurological disease. Alzheimers Res Ther 12 : 69, 2020 4) Miyashita S, Yamada T, Mikami T et al : Impact of dementia on clinical outcomes in elderly patients with coronavirus 2019 (COVID–19) : an experience in New York. Geriatr Gerontol Int 20 : 732–734, 2020 22) Mok VCT, Pendlebury S, Wong A et al : Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID–19 pandemic, now and in the future. Alzheimers Dement, 2020 Aug 12. doi : 10.1002/alz.12143. Online ahead 9) Yao JS, Dee EC, Milazzo C et al : Covid–19 in dementia : an insidious pandemic. Age Ageing 49 : 713–715, 2020 1) Romagunolo A, Balestrino R, Imbalzano G et al : Neurological comorbidity and severity of COVID–19. J Neurol, 2020 Aug 4. doi : 10.1007/s00415-020-10123-y. Online ahead 21) Yoshida K, Yamaoka Y, Eguchi Y et al : Remote neuropsychological assessment of elderly Japanese population using the Alzheimer's Disease Assessment Scale : A validation study. J Telemed Telecare 26 : 482–487, 2020 17) Capozzo R, Zoccolella S, Frisullo ME et al : Telemedicine for Delivery of Care in Frontotemporal Lobar Degeneration During COVID–19 Pandemic : Results from Southern Italy. J Alzheimers Dis 76 : 481–489, 2020 5) Korczyn AD : Dementia in the COVID–19 Period. J Alzheimers Dis 75 : 1071–1072, 2020 13) http://dementia.umin.jp/pdf/kekka.pdf（アクセス2020年9月29日） 19) Goodman–Casanova JM, Dura–Perez E, Guzman–Parra J et al : Telehealth Home Support During COVID–19 Confinement for Community–Dwelling Older Adults With Mild Cognitive Impairment or Mild Dementia : Survey Study. J Med Internet Res 22 : e19434, 2020 7) Onder G, Rezza G, Brusaferro S : Case–Fatality Rate and Characteristics of Patients Dying in Relation to COVID–19 in Italy. JAMA 323 : 1775–1776, 2020 23) Helms J, Kremer S, Merdji H et al : Neurologic Features in Severe SARS–CoV–2 Infection. N Engl J Med 382 : 2268–2270, 2020 2) Bianchetti A, Rozzini R, Guerini F et al : Clinical Presentation of COVID19 in Dementia Patients. J Nutr Health Aging 24 : 560–562, 2020 14) https://www.hiroshima-u.ac.jp/news/59484（アクセス2020年9月29日） 12) Canevelli M, Valletta M, Blasi MT et al : Facing Dementia During the COVID–19 Outbreak. J Am Geriatr Soc 68 : 1673–1676, 2020 16) Suzuki M, Hotta M, Nagase A et al : The behavioral pattern of patients with frontotemporal dementia during the COVID–19 pandemic. Int Psychogeriatr, 2020 Jun 10. doi : 10.1017/S104161022000109X. Online ahead 8) McMichael TM, Currie DW, Clark S et al : Epidemiology of Covid–19 in a Long–Term Care Facility in King County, Washington. N Engl J Med 382 : 2005–2011, 2020 10) Poloni TE, Carlos AF, Cairati M et al : Prevalence and prognostic value of Delirium as the initial presentation of COVID–19 in the elderly with dementia : An Italian retrospective study. EClinicalMedicine 100490, 2020 20) Iiboshi K, Yoshida K, Yamaoka Y et al : A Validation Study of the Remotely Administered Montreal Cognitive Assessment Tool in the Elderly Japanese Population. Telemed J E Health 26 : 920–928, 2020 11) Li J, Long X, Huang H et al : Resilience of Alzheimer's Disease to COVID–19. J Alzheimers Dis 77 : 67–73, 2020 18) Lai FHY, Yan EWH, Yu KKY et al : The Protective Impact of Telemedicine on Persons With Dementia and Their Caregivers During the COVID–19 Pandemic. Am J Geriatr Psychiatry S1064–7481(20)30438–3, 2020. doi : 10.1016/j.jagp.2020.07.019. Online ahead 15) Tsugawa A, Sakurai S, Inagawa Y et al : Awareness of the COVID–19 Outbreak and Resultant Depressive Tendencies in Patients with Severe Alzheimer's Disease. J Alzheimers Dis 77 : 539–541, 2020 24) Ardila A, Lahiri D : Executive dysfunction in COVID–19 patients. Diabetes Metab Syndr 14 : 1377–1378, 2020 6) Covino M, Matteis GD, Santoro M et al : Clinical characteristics and prognostic factors in COVID–19 patients aged ≥80 years. Geriatr Gerontol Int 20 : 704–708, 2020 |
| References_xml | – reference: 20) Iiboshi K, Yoshida K, Yamaoka Y et al : A Validation Study of the Remotely Administered Montreal Cognitive Assessment Tool in the Elderly Japanese Population. Telemed J E Health 26 : 920–928, 2020 – reference: 21) Yoshida K, Yamaoka Y, Eguchi Y et al : Remote neuropsychological assessment of elderly Japanese population using the Alzheimer's Disease Assessment Scale : A validation study. J Telemed Telecare 26 : 482–487, 2020 – reference: 8) McMichael TM, Currie DW, Clark S et al : Epidemiology of Covid–19 in a Long–Term Care Facility in King County, Washington. N Engl J Med 382 : 2005–2011, 2020 – reference: 25) Heneka MT, Golenbock D, Latz E et al : Immediate and long–term consequences of COVID–19 infections for the development of neurological disease. Alzheimers Res Ther 12 : 69, 2020 – reference: 7) Onder G, Rezza G, Brusaferro S : Case–Fatality Rate and Characteristics of Patients Dying in Relation to COVID–19 in Italy. JAMA 323 : 1775–1776, 2020 – reference: 1) Romagunolo A, Balestrino R, Imbalzano G et al : Neurological comorbidity and severity of COVID–19. J Neurol, 2020 Aug 4. doi : 10.1007/s00415-020-10123-y. Online ahead – reference: 11) Li J, Long X, Huang H et al : Resilience of Alzheimer's Disease to COVID–19. J Alzheimers Dis 77 : 67–73, 2020 – reference: 16) Suzuki M, Hotta M, Nagase A et al : The behavioral pattern of patients with frontotemporal dementia during the COVID–19 pandemic. Int Psychogeriatr, 2020 Jun 10. doi : 10.1017/S104161022000109X. Online ahead – reference: 3) Wan Y, Wu J, Lihua Ni L et al : Prognosis analysis of patients with mental disorders with COVID–19 : a single–center retrospective study. Aging (Albany NY) 12 : 11238–11244, 2020 – reference: 19) Goodman–Casanova JM, Dura–Perez E, Guzman–Parra J et al : Telehealth Home Support During COVID–19 Confinement for Community–Dwelling Older Adults With Mild Cognitive Impairment or Mild Dementia : Survey Study. J Med Internet Res 22 : e19434, 2020 – reference: 22) Mok VCT, Pendlebury S, Wong A et al : Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID–19 pandemic, now and in the future. Alzheimers Dement, 2020 Aug 12. doi : 10.1002/alz.12143. Online ahead – reference: 23) Helms J, Kremer S, Merdji H et al : Neurologic Features in Severe SARS–CoV–2 Infection. N Engl J Med 382 : 2268–2270, 2020 – reference: 4) Miyashita S, Yamada T, Mikami T et al : Impact of dementia on clinical outcomes in elderly patients with coronavirus 2019 (COVID–19) : an experience in New York. Geriatr Gerontol Int 20 : 732–734, 2020 – reference: 12) Canevelli M, Valletta M, Blasi MT et al : Facing Dementia During the COVID–19 Outbreak. J Am Geriatr Soc 68 : 1673–1676, 2020 – reference: 5) Korczyn AD : Dementia in the COVID–19 Period. J Alzheimers Dis 75 : 1071–1072, 2020 – reference: 14) https://www.hiroshima-u.ac.jp/news/59484（アクセス2020年9月29日） – reference: 18) Lai FHY, Yan EWH, Yu KKY et al : The Protective Impact of Telemedicine on Persons With Dementia and Their Caregivers During the COVID–19 Pandemic. Am J Geriatr Psychiatry S1064–7481(20)30438–3, 2020. doi : 10.1016/j.jagp.2020.07.019. Online ahead – reference: 6) Covino M, Matteis GD, Santoro M et al : Clinical characteristics and prognostic factors in COVID–19 patients aged ≥80 years. Geriatr Gerontol Int 20 : 704–708, 2020 – reference: 2) Bianchetti A, Rozzini R, Guerini F et al : Clinical Presentation of COVID19 in Dementia Patients. J Nutr Health Aging 24 : 560–562, 2020 – reference: 9) Yao JS, Dee EC, Milazzo C et al : Covid–19 in dementia : an insidious pandemic. Age Ageing 49 : 713–715, 2020 – reference: 10) Poloni TE, Carlos AF, Cairati M et al : Prevalence and prognostic value of Delirium as the initial presentation of COVID–19 in the elderly with dementia : An Italian retrospective study. EClinicalMedicine 100490, 2020 – reference: 17) Capozzo R, Zoccolella S, Frisullo ME et al : Telemedicine for Delivery of Care in Frontotemporal Lobar Degeneration During COVID–19 Pandemic : Results from Southern Italy. J Alzheimers Dis 76 : 481–489, 2020 – reference: 24) Ardila A, Lahiri D : Executive dysfunction in COVID–19 patients. Diabetes Metab Syndr 14 : 1377–1378, 2020 – reference: 13) http://dementia.umin.jp/pdf/kekka.pdf（アクセス2020年9月29日） – reference: 15) Tsugawa A, Sakurai S, Inagawa Y et al : Awareness of the COVID–19 Outbreak and Resultant Depressive Tendencies in Patients with Severe Alzheimer's Disease. J Alzheimers Dis 77 : 539–541, 2020 |
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| Title | COVID–19と認知症診療 |
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