横隔膜部胸膜より発生した石灰化線維性偽腫瘍の一例
症例は58歳の女性．健康診断の胸部X線で異常を指摘され来院した．胸部CTでは右の肋骨横隔膜角部に 4×2cm大の漸増性に造影される腫瘤影を認め，胸部MRI所見ではT2強調画像で著明な低信号を示し孤立性線維性腫瘍等を疑い，胸腔鏡下手術を施行した．手術所見で横隔膜部胸膜より発生した有茎性腫瘍を認めた．腫瘍は，病理検査所見では細胞成分の少ない線維性組織が主体で異型細胞は認めず砂粒状石灰化が認められ，免疫染色ではvimentinが陽性で，CD34，α-SMA，ALK-1は陰性であり，石灰化線維性偽腫瘍（Calcifying fibrous pseudotumor）と診断された．本症は稀な疾患ではあるが...
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| Published in | 日本呼吸器外科学会雑誌 Vol. 26; no. 4; pp. 453 - 458 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
特定非営利活動法人 日本呼吸器外科学会
2012
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0919-0945 1881-4158 |
| DOI | 10.2995/jacsurg.26.453 |
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| Abstract | 症例は58歳の女性．健康診断の胸部X線で異常を指摘され来院した．胸部CTでは右の肋骨横隔膜角部に 4×2cm大の漸増性に造影される腫瘤影を認め，胸部MRI所見ではT2強調画像で著明な低信号を示し孤立性線維性腫瘍等を疑い，胸腔鏡下手術を施行した．手術所見で横隔膜部胸膜より発生した有茎性腫瘍を認めた．腫瘍は，病理検査所見では細胞成分の少ない線維性組織が主体で異型細胞は認めず砂粒状石灰化が認められ，免疫染色ではvimentinが陽性で，CD34，α-SMA，ALK-1は陰性であり，石灰化線維性偽腫瘍（Calcifying fibrous pseudotumor）と診断された．本症は稀な疾患ではあるが胸腔内腫瘍の鑑別の一つとして念頭に置くべき疾患と考えられた． |
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| AbstractList | 症例は58歳の女性．健康診断の胸部X線で異常を指摘され来院した．胸部CTでは右の肋骨横隔膜角部に 4×2cm大の漸増性に造影される腫瘤影を認め，胸部MRI所見ではT2強調画像で著明な低信号を示し孤立性線維性腫瘍等を疑い，胸腔鏡下手術を施行した．手術所見で横隔膜部胸膜より発生した有茎性腫瘍を認めた．腫瘍は，病理検査所見では細胞成分の少ない線維性組織が主体で異型細胞は認めず砂粒状石灰化が認められ，免疫染色ではvimentinが陽性で，CD34，α-SMA，ALK-1は陰性であり，石灰化線維性偽腫瘍（Calcifying fibrous pseudotumor）と診断された．本症は稀な疾患ではあるが胸腔内腫瘍の鑑別の一つとして念頭に置くべき疾患と考えられた． |
| Author | 井上, 修平 大内, 政嗣 手塚, 則明 花岡, 淳 藤田, 琢也 尾崎, 良智 |
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| References | 2) Rosenthal NS, Abdul-Karim FW. Childhood fibrous tumor with psammoma bodies. Clinicopathologic features in two cases. Arch Pathol Lab Med 1988; 112: 798-800. 14) Pinkard NB, Wilson RW, Lawless N, et al. Calcifying fibrous pseudotumor of pleura. A report of three cases of a newly described entity involving the pleura. Am J Clin Pathol 1996; 105: 189-94. 1) Fetsch JF, Montgomery EA, Meis JM. Calcifying fibrous pseudotumor. Am J Surg Pathol 1993; 17: 502-8. 9) Soyer T, Ciftci AO, Gucer S, Orhan D, Senocak ME. Calcifying fibrous pseudotumor of lung: a previously unreported entity. J Pediatr Surg 2004; 39: 1729-30. 20) Maeda A, Kawabata K, Kusuzaki K. Rapid recurrence of calcifying fibrous pseudotumor (a case report). Anticancer Res 2002; 22: 1795-7. 6) 宮野 裕，神崎正人，小原徹也，大貫恭正．胸膜に多発した石灰化線維性偽腫瘍．胸部外科 2008; 61: 857-60. 17) 安川元章，中川勝裕，桂 浩，岩崎輝夫，中根 茂，大瀬尚子．胸膜に発生した多発性石灰化線維性偽腫瘍の1例．日呼外会誌 2006; 20: 677-81. 10) Ammar A, El Hammami S, Horchani H, Sellami N, Kilani T. Calcifying fibrous pseudotumor of the pleura: a rare location. Ann Thorac Surg 2003; 76: 2081-2. 16) 横須賀哲哉，小林利子．壁側胸膜に発生したCalcifying Fibrous Tumorの1胸腔鏡下切除例．日呼外会誌 2010; 24: 35-8. 7) Shibata K, Yuki D, Sakata K. Multiple calcifying fibrous pseudotumors disseminated in the pleura. Ann Thorac Surg 2008; 85: e3-5. 13) Jeong HS, Lee GK, Sung R, Ahn JH, Song HG. Calcifying fibrous pseudotumor of mediastinum--a case report. J Korean Med Sci 1997; 12: 58-62. 3) Isaka M, Nakagawa K, Maniwa T, et al. Disseminated calcifying tumor of the pleura: review of the literature and a case report with immunohistochemical study of its histogenesis. Gen Thorac Cardiovasc Surg 2011; 59: 579-82. 11) Cavazza A, Gelli MC, Agostini L, Sgarbi G, De Marco L, Gardini G. Calcified pseudotumor of the pleura: description of a case. Pathologica 2002; 94: 201-5. 15) Rudez I, Legac A, Baric D, Manojlovic S, Unic D, Sutlic Z. Asymptomatic calcifying fibrous pseudotumor compressing heart cavities. Ann Thorac Surg 2011; 91: 291-3. 5) Suh JH, Shin OR, Kim YH. Multiple calcifying fibrous pseudotumor of the pleura. J Thorac Oncol 2008; 3: 1356-8. 18) 橋詰壽律，阿部良行，梅村しのぶ．著明な硝子化を伴った孤立性線維性胸膜腫瘍の1胸腔鏡下摘出例．日呼外会誌 2000; 14: 77-81. 19) Chon SH, Lee CB, Oh YH. Calcifying fibrous pseudotumor causing thoracic outlet syndrome. Eur J Cardiothorac Surg 2005; 27: 353-5. 4) Jiang K, Nie J, Wang J, Li J. Multiple calcifying fibrous pseudotumor of the bilateral pleura. Jpn J Clin Oncol 2011; 41: 130-3. 12) Hainaut P, Lesage V, Weynand B, Coche E, Noirhomme P. Calcifying fibrous pseudotumor (CFPT): a patient presenting with multiple pleural lesions. Acta Clin Belg 1999; 54: 162-4. 21) Van Dorpe J, Ectors N, Geboes K, D'Hoore A, Sciot R. Is calcifying fibrous pseudotumor a late sclerosing stage of inflammatory myofibroblastic tumor? Am J Surg Pathol 1999; 23: 329-35. 8) Jang KS, Oh YH, Han HX, et al. Calcifying fibrous pseudotumor of the pleura. Ann Thorac Surg 2004; 78: e87-8. |
| References_xml | – reference: 10) Ammar A, El Hammami S, Horchani H, Sellami N, Kilani T. Calcifying fibrous pseudotumor of the pleura: a rare location. Ann Thorac Surg 2003; 76: 2081-2. – reference: 19) Chon SH, Lee CB, Oh YH. Calcifying fibrous pseudotumor causing thoracic outlet syndrome. Eur J Cardiothorac Surg 2005; 27: 353-5. – reference: 20) Maeda A, Kawabata K, Kusuzaki K. Rapid recurrence of calcifying fibrous pseudotumor (a case report). Anticancer Res 2002; 22: 1795-7. – reference: 5) Suh JH, Shin OR, Kim YH. Multiple calcifying fibrous pseudotumor of the pleura. J Thorac Oncol 2008; 3: 1356-8. – reference: 1) Fetsch JF, Montgomery EA, Meis JM. Calcifying fibrous pseudotumor. Am J Surg Pathol 1993; 17: 502-8. – reference: 8) Jang KS, Oh YH, Han HX, et al. Calcifying fibrous pseudotumor of the pleura. Ann Thorac Surg 2004; 78: e87-8. – reference: 11) Cavazza A, Gelli MC, Agostini L, Sgarbi G, De Marco L, Gardini G. Calcified pseudotumor of the pleura: description of a case. Pathologica 2002; 94: 201-5. – reference: 9) Soyer T, Ciftci AO, Gucer S, Orhan D, Senocak ME. Calcifying fibrous pseudotumor of lung: a previously unreported entity. J Pediatr Surg 2004; 39: 1729-30. – reference: 17) 安川元章，中川勝裕，桂 浩，岩崎輝夫，中根 茂，大瀬尚子．胸膜に発生した多発性石灰化線維性偽腫瘍の1例．日呼外会誌 2006; 20: 677-81. – reference: 18) 橋詰壽律，阿部良行，梅村しのぶ．著明な硝子化を伴った孤立性線維性胸膜腫瘍の1胸腔鏡下摘出例．日呼外会誌 2000; 14: 77-81. – reference: 4) Jiang K, Nie J, Wang J, Li J. Multiple calcifying fibrous pseudotumor of the bilateral pleura. Jpn J Clin Oncol 2011; 41: 130-3. – reference: 3) Isaka M, Nakagawa K, Maniwa T, et al. Disseminated calcifying tumor of the pleura: review of the literature and a case report with immunohistochemical study of its histogenesis. Gen Thorac Cardiovasc Surg 2011; 59: 579-82. – reference: 12) Hainaut P, Lesage V, Weynand B, Coche E, Noirhomme P. Calcifying fibrous pseudotumor (CFPT): a patient presenting with multiple pleural lesions. Acta Clin Belg 1999; 54: 162-4. – reference: 2) Rosenthal NS, Abdul-Karim FW. Childhood fibrous tumor with psammoma bodies. Clinicopathologic features in two cases. Arch Pathol Lab Med 1988; 112: 798-800. – reference: 7) Shibata K, Yuki D, Sakata K. Multiple calcifying fibrous pseudotumors disseminated in the pleura. Ann Thorac Surg 2008; 85: e3-5. – reference: 15) Rudez I, Legac A, Baric D, Manojlovic S, Unic D, Sutlic Z. Asymptomatic calcifying fibrous pseudotumor compressing heart cavities. Ann Thorac Surg 2011; 91: 291-3. – reference: 21) Van Dorpe J, Ectors N, Geboes K, D'Hoore A, Sciot R. Is calcifying fibrous pseudotumor a late sclerosing stage of inflammatory myofibroblastic tumor? Am J Surg Pathol 1999; 23: 329-35. – reference: 6) 宮野 裕，神崎正人，小原徹也，大貫恭正．胸膜に多発した石灰化線維性偽腫瘍．胸部外科 2008; 61: 857-60. – reference: 13) Jeong HS, Lee GK, Sung R, Ahn JH, Song HG. Calcifying fibrous pseudotumor of mediastinum--a case report. J Korean Med Sci 1997; 12: 58-62. – reference: 14) Pinkard NB, Wilson RW, Lawless N, et al. Calcifying fibrous pseudotumor of pleura. A report of three cases of a newly described entity involving the pleura. Am J Clin Pathol 1996; 105: 189-94. – reference: 16) 横須賀哲哉，小林利子．壁側胸膜に発生したCalcifying Fibrous Tumorの1胸腔鏡下切除例．日呼外会誌 2010; 24: 35-8. |
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| Snippet | 症例は58歳の女性．健康診断の胸部X線で異常を指摘され来院した．胸部CTでは右の肋骨横隔膜角部に 4×2cm大の漸増性に造影される腫瘤影を認め，胸部MRI所見ではT2強調画... |
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| SubjectTerms | 孤立性線維性腫瘍 石灰化線維性偽腫瘍 胸腔鏡下切除 |
| Title | 横隔膜部胸膜より発生した石灰化線維性偽腫瘍の一例 |
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