がん治療関連心機能障害(CTRCD)

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Published inShinzo Vol. 52; no. 12; pp. 1324 - 1331
Main Author 前嶋, 康浩
Format Journal Article
LanguageJapanese
Published 公益財団法人 日本心臓財団 25.12.2020
Japan Heart Foundation
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ISSN0586-4488
2186-3016
DOI10.11281/shinzo.52.1324

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Author 前嶋, 康浩
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  organization: 東京医科歯科大学大学院医歯学総合研究科 循環制御内科学
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References 28) Nishimura H, Okazaki T, Tanaka Y, et al:Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science 2001;291:319-322
18) Losordo DW, Vale PR, Symes JF, et al:Gene therapy for myocardial angiogenesis:Initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia. Circulation 1998;98:2800-2804
13) Patnaik JL, Byers T, DiGuiseppi C, et al:Cardiovascular disease competes with breast cancer as the leading cause of death for older females diagnosed with breast cancer:A retrospective cohort study. Breast Cancer Res 2011;13:R64
19) Li W, Croce K, Steensma DP, et al:Vascular and metabolic implications of novel targeted cancer therapies:Focus on kinase inhibitors. J Am Coll Cardiol 2015;66:1160-1178
11) Woyach JA, Ruppert AS, Heerema NA, et al:Ibrutinib regimens versus chemoimmunotherapy in older patients with untreated cll. N Engl J Med 2018;379:2517-2528
12) Caldeira D, Alves D, Costa J, et al:Ibrutinib increases the risk of hypertension and atrial fibrillation:Systematic review and meta-analysis. PLoS One 2019;14:e0211228
15) Garcia-Pavia P, Kim Y, Restrepo-Cordoba MA, et al:Genetic variants associated with cancer therapy-induced cardiomyopathy. Circulation 2019;140:31-41
3) van Leeuwen RW, van Gelder T, Mathijssen RH, Jansman FG:Drug-drug interactions with tyrosine-kinase inhibitors:A clinical perspective. Lancet Oncol 2014;15:e315-326
14) Bowles EJ, Wellman R, Feigelson HS, et al:Risk of heart failure in breast cancer patients after anthracycline and trastuzumab treatment:A retrospective cohort study. J Natl Cancer Inst 2012;104:1293-1305
25) Yasuda S, Kaikita K, Akao M, et al:Antithrombotic therapy for atrial fibrillation with stable coronary disease. N Engl J Med 2019;381:1103-1113
23) Young AM, Marshall A, Thirlwall J, et al:Comparison of an oral factor xa inhibitor with low molecular weight heparin in patients with cancer with venous thromboembolism:Results of a randomized trial(SELECT-D). J Clin Oncol 2018;36:2017-2023
29) Johnson DB, Balko JM, Compton ML, et al:Fulminant myocarditis with combination immune checkpoint blockade. N Engl J Med 2016;375:1749-1755
7) Brixey AG, Light RW:Pleural effusions due to dasatinib. Curr Opin Pulm Med 2010;16:351-356
10) Anand K, Ensor J, Trachtenberg B, Bernicker E:Osimertinib-induced cardiotoxicity:A retrospective review of the fda adverse events reporting system(faers). J Am Coll Cardiol CardioOnc 2019;1:172-178
24) Agnelli G, Becattini C, Meyer G, et al:Apixaban for the treatment of venous thromboembolism associated with cancer. N Engl J Med 2020;382:1599-1607
2) Khorana AA:Venous thromboembolism and prognosis in cancer. Thromb Res 2010;125:490-493
21) Farmakis D, Parissis J, Filippatos G:Insights into onco-cardiology:Atrial fibrillation in cancer. J Am Coll Cardiol 2014;63:945-953
31) Zhou YW, Zhu YJ, Wang MN, et al:Immune checkpoint inhibitor-associated cardiotoxicity:Current understanding on its mechanism, diagnosis and management. Front Pharmacol 2019;10:1350
20) Hall PS, Harshman LC, Srinivas S, Witteles RM:The frequency and severity of cardiovascular toxicity from targeted therapy in advanced renal cell carcinoma patients. JACC Heart Fail 2013;1:72-78
22) Raskob GE, van Es N, Verhamme P, et al:Edoxaban for the treatment of cancer-associated venous thromboembolism. N Engl J Med 2018;378:615-624
26) Curran CS, Sommers CL, Young HA, et al:Report on the 2018 cancer, autoimmunity, and immunology conference. J Immunol 2019;202:2823-2828
9) Zaborowska-Szmit M, Krzakowski M, Kowalski DM, Szmit S:Cardiovascular complications of systemic therapy in non-small-cell lung cancer. J Clin Med 2020;9:1268
5) Kerkelä R, Grazette L, Yacobi R, et al:Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat Med 2006;12:908-916
6) Lekes D, Szadvari I, Krizanova O, et al:Nilotinib induces er stress and cell death in h9c2 cells. Physiol Res 2016;65:S505-S514
8) Casavecchia G, Galderisi M, Novo G, et al:Early diagnosis, clinical management, and follow-up of cardiovascular events with ponatinib. Heart Fail Rev 2020;25:447-456
4) Okada K, Minamino T, Tsukamoto Y, et al:Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction:Possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis. Circulation 2004;110:705-712
16) Aminkeng F, Bhavsar AP, Visscher H, et al:A coding variant in rarg confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer. Nat Genet 2015;47:1079-1084
17) Isner JM, Pieczek A, Schainfeld R, et al:Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb. Lancet 1996;348:370-374
27) Topalian SL, Hodi FS, Brahmer JR, et al:Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012;366:2443-2454
30) Awadalla M, Mahmood SS, Groarke JD, et al:Global longitudinal strain and cardiac events in patients with immune checkpoint inhibitor-related myocarditis. J Am Coll Cardiol 2020;75:467-478
1) Ewer MS, Ewer SM:Cardiotoxicity of anticancer treatments. Nat Rev Cardiol 2015;12:547-558
References_xml – reference: 28) Nishimura H, Okazaki T, Tanaka Y, et al:Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science 2001;291:319-322
– reference: 29) Johnson DB, Balko JM, Compton ML, et al:Fulminant myocarditis with combination immune checkpoint blockade. N Engl J Med 2016;375:1749-1755
– reference: 27) Topalian SL, Hodi FS, Brahmer JR, et al:Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012;366:2443-2454
– reference: 10) Anand K, Ensor J, Trachtenberg B, Bernicker E:Osimertinib-induced cardiotoxicity:A retrospective review of the fda adverse events reporting system(faers). J Am Coll Cardiol CardioOnc 2019;1:172-178
– reference: 5) Kerkelä R, Grazette L, Yacobi R, et al:Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat Med 2006;12:908-916
– reference: 19) Li W, Croce K, Steensma DP, et al:Vascular and metabolic implications of novel targeted cancer therapies:Focus on kinase inhibitors. J Am Coll Cardiol 2015;66:1160-1178
– reference: 20) Hall PS, Harshman LC, Srinivas S, Witteles RM:The frequency and severity of cardiovascular toxicity from targeted therapy in advanced renal cell carcinoma patients. JACC Heart Fail 2013;1:72-78
– reference: 4) Okada K, Minamino T, Tsukamoto Y, et al:Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction:Possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis. Circulation 2004;110:705-712
– reference: 6) Lekes D, Szadvari I, Krizanova O, et al:Nilotinib induces er stress and cell death in h9c2 cells. Physiol Res 2016;65:S505-S514
– reference: 24) Agnelli G, Becattini C, Meyer G, et al:Apixaban for the treatment of venous thromboembolism associated with cancer. N Engl J Med 2020;382:1599-1607
– reference: 31) Zhou YW, Zhu YJ, Wang MN, et al:Immune checkpoint inhibitor-associated cardiotoxicity:Current understanding on its mechanism, diagnosis and management. Front Pharmacol 2019;10:1350
– reference: 3) van Leeuwen RW, van Gelder T, Mathijssen RH, Jansman FG:Drug-drug interactions with tyrosine-kinase inhibitors:A clinical perspective. Lancet Oncol 2014;15:e315-326
– reference: 2) Khorana AA:Venous thromboembolism and prognosis in cancer. Thromb Res 2010;125:490-493
– reference: 9) Zaborowska-Szmit M, Krzakowski M, Kowalski DM, Szmit S:Cardiovascular complications of systemic therapy in non-small-cell lung cancer. J Clin Med 2020;9:1268
– reference: 12) Caldeira D, Alves D, Costa J, et al:Ibrutinib increases the risk of hypertension and atrial fibrillation:Systematic review and meta-analysis. PLoS One 2019;14:e0211228
– reference: 30) Awadalla M, Mahmood SS, Groarke JD, et al:Global longitudinal strain and cardiac events in patients with immune checkpoint inhibitor-related myocarditis. J Am Coll Cardiol 2020;75:467-478
– reference: 11) Woyach JA, Ruppert AS, Heerema NA, et al:Ibrutinib regimens versus chemoimmunotherapy in older patients with untreated cll. N Engl J Med 2018;379:2517-2528
– reference: 23) Young AM, Marshall A, Thirlwall J, et al:Comparison of an oral factor xa inhibitor with low molecular weight heparin in patients with cancer with venous thromboembolism:Results of a randomized trial(SELECT-D). J Clin Oncol 2018;36:2017-2023
– reference: 13) Patnaik JL, Byers T, DiGuiseppi C, et al:Cardiovascular disease competes with breast cancer as the leading cause of death for older females diagnosed with breast cancer:A retrospective cohort study. Breast Cancer Res 2011;13:R64
– reference: 26) Curran CS, Sommers CL, Young HA, et al:Report on the 2018 cancer, autoimmunity, and immunology conference. J Immunol 2019;202:2823-2828
– reference: 14) Bowles EJ, Wellman R, Feigelson HS, et al:Risk of heart failure in breast cancer patients after anthracycline and trastuzumab treatment:A retrospective cohort study. J Natl Cancer Inst 2012;104:1293-1305
– reference: 17) Isner JM, Pieczek A, Schainfeld R, et al:Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb. Lancet 1996;348:370-374
– reference: 1) Ewer MS, Ewer SM:Cardiotoxicity of anticancer treatments. Nat Rev Cardiol 2015;12:547-558
– reference: 8) Casavecchia G, Galderisi M, Novo G, et al:Early diagnosis, clinical management, and follow-up of cardiovascular events with ponatinib. Heart Fail Rev 2020;25:447-456
– reference: 22) Raskob GE, van Es N, Verhamme P, et al:Edoxaban for the treatment of cancer-associated venous thromboembolism. N Engl J Med 2018;378:615-624
– reference: 7) Brixey AG, Light RW:Pleural effusions due to dasatinib. Curr Opin Pulm Med 2010;16:351-356
– reference: 21) Farmakis D, Parissis J, Filippatos G:Insights into onco-cardiology:Atrial fibrillation in cancer. J Am Coll Cardiol 2014;63:945-953
– reference: 15) Garcia-Pavia P, Kim Y, Restrepo-Cordoba MA, et al:Genetic variants associated with cancer therapy-induced cardiomyopathy. Circulation 2019;140:31-41
– reference: 25) Yasuda S, Kaikita K, Akao M, et al:Antithrombotic therapy for atrial fibrillation with stable coronary disease. N Engl J Med 2019;381:1103-1113
– reference: 16) Aminkeng F, Bhavsar AP, Visscher H, et al:A coding variant in rarg confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer. Nat Genet 2015;47:1079-1084
– reference: 18) Losordo DW, Vale PR, Symes JF, et al:Gene therapy for myocardial angiogenesis:Initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia. Circulation 1998;98:2800-2804
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