重症虚血肢の再生医療
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| Published in | Shinzo Vol. 49; no. 3; pp. 232 - 239 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
公益財団法人 日本心臓財団
2017
Japan Heart Foundation |
| Online Access | Get full text |
| ISSN | 0586-4488 2186-3016 |
| DOI | 10.11281/shinzo.49.232 |
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| Author | 室原, 豊明 柴田, 玲 林田, 竜 近藤, 和久 |
|---|---|
| Author_xml | – sequence: 1 fullname: 室原, 豊明 organization: 名古屋大学大学院医学系研究科 循環器内科学講座 – sequence: 1 fullname: 柴田, 玲 organization: 名古屋大学大学院医学系研究科 先端循環器治療学寄附講座 – sequence: 1 fullname: 近藤, 和久 organization: 名古屋大学大学院医学系研究科 循環器内科学講座 – sequence: 1 fullname: 林田, 竜 organization: 名古屋大学大学院医学系研究科 循環器内科学講座 |
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| Copyright | 2017 公益財団法人 日本心臓財団 |
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| References | 10) Vasa M, Fichtlscherer S, Aicher A, et al：Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 2001；89：E1-7 14) Fadini GP, Miorin M, Facco M, et al：Circulating endothelial progenitor cells are reduced in peripheral vascular complications of type 2 diabetes mellitus. J Am Coll Cardiol 2005；45：1449-1457 29) Lee HC, An SG, Lee HW, et al：Safety and effect of adipose tissue-derived stem cell implantation in patients with critical limb ischemia：a pilot study. Circ J 2012；76：1750-1760 16) Grochot-Przeczek A, Dulak J, Jozkowicz A：Therapeutic angiogenesis for revascularization in peripheral artery disease. Gene 2013；525：220-228 11) Hill JM, Zalos G, Halcox JP, et al：Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 2003；348：593-600 7) Benoit E, O’Donnell TF, Patel AN：Safety and efficacy of autologous cell therapy in critical limb ischemia：a systematic review. Cell Transplant 2013；22：545-562 28) Hiasa K, Ishibashi M, Ohtani K, et al：Gene transfer of stromal cell-derived factor-1alpha enhances ischemic vasculogenesis and angiogenesis via vascular endothelial growth factor/endothelial nitric oxide synthase-related pathway：next-generation chemokine therapy for therapeutic neovascularization. Circulation 2004；109：2454-2461 21) Takahashi K, Yamanaka S：Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006；126：663-676 30) Bura A, Planat-Benard V, Bourin P, et al：Phase I trial：the use of autologous cultured adipose-derived stroma/stem cells to treat patients with non-revascularizable critical limb ischemia. Cytotherapy 2014；16：245-257 23) Zuk PA, Zhu M, Ashjian P, et al：Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 2002；13：4279-4295 1) Isner JM, Pieczek A, Symes JF, et al：Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb. Lancet 1996；348：370-374 12) Heeschen C, Lehmann R, Honold J, et al：Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease. Circulation 2004；109：1615-1622 13) Fadini GP, Sartore S, Albiero M, et al：Number and function of endothelial progenitor cells as a marker of severity for diabetic vasculopathy. Arterioscler Thromb Vasc Biol 2006；26：2140-2146 22) Pittenger MF, Mackay AM, Beck SC, et al：Multilineage potential of adult human mesenchymal stem cells. Science 1999；284：143-147 20) Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al：Embryonic stem cell lines derived from human blastocysts. Science 1998；282：1145-1147 26) Traktuev DO, Merfeld-Clauss S, Li J, Kolonin M, et al：A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize endothelial networks. Circ Res 2008；102：77-85 27) Nagasawa T, Nakajima T, Tachibana K, et al：Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin. Proc Natl Acad Sci U S A 1996；93：14726-14729 3) Murohara T, Ikeda H, Duan J, et al：Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization. J Clin Invest 2000；105：1527-1536 19) Peeters Weem SM, Teraa M, de Borst GJ, et al：Bone Marrow derived Cell Therapy in Critical Limb Ischemia：A Meta-analysis of Randomized Placebo Controlled Trials. Eur J Vasc Endovasc Surg 2015；50：775-783 8) Matoba S, Tatsumi T, Murohara T, et al：Long-term clinical outcome after intramuscular implantation of bone marrow mononuclear cells（Therapeutic Angiogenesis by Cell Transplantation［TACT］ trial） in patients with chronic limb ischemia. Am Heart J 2008；156：1010-1018 4) Shintani S, Murohara T, Ikeda H, et al：Augmentation of postnatal neovascularization with autologous bone marrow transplantation. Circulation 2001；103：897-903 18) De Haro J, Acin F, Lopez-Quintana A, et al：Meta-analysis of randomized, controlled clinical trials in angiogenesis：gene and cell therapy in peripheral arterial disease. Heart Vessels 2009；24：321-328 6) Fadini GP, Agostini C, Avogaro A：Autologous stem cell therapy for peripheral arterial disease meta-analysis and systematic review of the literature. Atherosclerosis 2010；209：10-17 25) Kondo K, Shintani S, Shibata R, et al：Implantation of adipose-derived regenerative cells enhances ischemia-induced angiogenesis. Arterioscler Thromb Vasc Biol 2009；29：61-66 5) Tateishi-Yuyama E, Matsubara H, Murohara T, et al：Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells：a pilot study and a randomised controlled trial. Lancet 2002；360：427-435 9) Idei N, Soga J, Hata T, et al：Autologous bone-marrow mononuclear cell implantation reduces long-term major amputation risk in patients with critical limb ischemia：a comparison of atherosclerotic peripheral arterial disease and Buerger disease. Circ Cardiovasc Interv 2011；4：15-25 17) Teraa M, Sprengers RW, van der Graaf Y, et al：Autologous bone marrow-derived cell therapy in patients with critical limb ischemia：a meta-analysis of randomized controlled clinical trials. Ann Surg 2013；258：922-929 2) Asahara T, Murohara T, Sullivan A, et al：Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997；275：964-967 24) Murohara T, Shintani S, Kondo K：Autologous adipose-derived regenerative cells for therapeutic angiogenesis. Curr Pharm Des 2009；15：2784-2790 15) Choi JH, Kim KL, Huh W, et al：Decreased number and impaired angiogenic function of endothelial progenitor cells in patients with chronic renal failure. Arterioscler Thromb Vasc Biol 2004；24：1246-1252 |
| References_xml | – reference: 19) Peeters Weem SM, Teraa M, de Borst GJ, et al：Bone Marrow derived Cell Therapy in Critical Limb Ischemia：A Meta-analysis of Randomized Placebo Controlled Trials. Eur J Vasc Endovasc Surg 2015；50：775-783 – reference: 28) Hiasa K, Ishibashi M, Ohtani K, et al：Gene transfer of stromal cell-derived factor-1alpha enhances ischemic vasculogenesis and angiogenesis via vascular endothelial growth factor/endothelial nitric oxide synthase-related pathway：next-generation chemokine therapy for therapeutic neovascularization. Circulation 2004；109：2454-2461 – reference: 3) Murohara T, Ikeda H, Duan J, et al：Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization. J Clin Invest 2000；105：1527-1536 – reference: 4) Shintani S, Murohara T, Ikeda H, et al：Augmentation of postnatal neovascularization with autologous bone marrow transplantation. Circulation 2001；103：897-903 – reference: 7) Benoit E, O’Donnell TF, Patel AN：Safety and efficacy of autologous cell therapy in critical limb ischemia：a systematic review. Cell Transplant 2013；22：545-562 – reference: 22) Pittenger MF, Mackay AM, Beck SC, et al：Multilineage potential of adult human mesenchymal stem cells. Science 1999；284：143-147 – reference: 15) Choi JH, Kim KL, Huh W, et al：Decreased number and impaired angiogenic function of endothelial progenitor cells in patients with chronic renal failure. Arterioscler Thromb Vasc Biol 2004；24：1246-1252 – reference: 18) De Haro J, Acin F, Lopez-Quintana A, et al：Meta-analysis of randomized, controlled clinical trials in angiogenesis：gene and cell therapy in peripheral arterial disease. Heart Vessels 2009；24：321-328 – reference: 30) Bura A, Planat-Benard V, Bourin P, et al：Phase I trial：the use of autologous cultured adipose-derived stroma/stem cells to treat patients with non-revascularizable critical limb ischemia. Cytotherapy 2014；16：245-257 – reference: 17) Teraa M, Sprengers RW, van der Graaf Y, et al：Autologous bone marrow-derived cell therapy in patients with critical limb ischemia：a meta-analysis of randomized controlled clinical trials. Ann Surg 2013；258：922-929 – reference: 5) Tateishi-Yuyama E, Matsubara H, Murohara T, et al：Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells：a pilot study and a randomised controlled trial. Lancet 2002；360：427-435 – reference: 14) Fadini GP, Miorin M, Facco M, et al：Circulating endothelial progenitor cells are reduced in peripheral vascular complications of type 2 diabetes mellitus. J Am Coll Cardiol 2005；45：1449-1457 – reference: 26) Traktuev DO, Merfeld-Clauss S, Li J, Kolonin M, et al：A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize endothelial networks. Circ Res 2008；102：77-85 – reference: 1) Isner JM, Pieczek A, Symes JF, et al：Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb. Lancet 1996；348：370-374 – reference: 2) Asahara T, Murohara T, Sullivan A, et al：Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997；275：964-967 – reference: 16) Grochot-Przeczek A, Dulak J, Jozkowicz A：Therapeutic angiogenesis for revascularization in peripheral artery disease. Gene 2013；525：220-228 – reference: 23) Zuk PA, Zhu M, Ashjian P, et al：Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 2002；13：4279-4295 – reference: 25) Kondo K, Shintani S, Shibata R, et al：Implantation of adipose-derived regenerative cells enhances ischemia-induced angiogenesis. Arterioscler Thromb Vasc Biol 2009；29：61-66 – reference: 24) Murohara T, Shintani S, Kondo K：Autologous adipose-derived regenerative cells for therapeutic angiogenesis. Curr Pharm Des 2009；15：2784-2790 – reference: 10) Vasa M, Fichtlscherer S, Aicher A, et al：Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 2001；89：E1-7 – reference: 27) Nagasawa T, Nakajima T, Tachibana K, et al：Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin. Proc Natl Acad Sci U S A 1996；93：14726-14729 – reference: 21) Takahashi K, Yamanaka S：Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006；126：663-676 – reference: 20) Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al：Embryonic stem cell lines derived from human blastocysts. Science 1998；282：1145-1147 – reference: 9) Idei N, Soga J, Hata T, et al：Autologous bone-marrow mononuclear cell implantation reduces long-term major amputation risk in patients with critical limb ischemia：a comparison of atherosclerotic peripheral arterial disease and Buerger disease. Circ Cardiovasc Interv 2011；4：15-25 – reference: 12) Heeschen C, Lehmann R, Honold J, et al：Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease. Circulation 2004；109：1615-1622 – reference: 11) Hill JM, Zalos G, Halcox JP, et al：Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 2003；348：593-600 – reference: 6) Fadini GP, Agostini C, Avogaro A：Autologous stem cell therapy for peripheral arterial disease meta-analysis and systematic review of the literature. Atherosclerosis 2010；209：10-17 – reference: 13) Fadini GP, Sartore S, Albiero M, et al：Number and function of endothelial progenitor cells as a marker of severity for diabetic vasculopathy. Arterioscler Thromb Vasc Biol 2006；26：2140-2146 – reference: 29) Lee HC, An SG, Lee HW, et al：Safety and effect of adipose tissue-derived stem cell implantation in patients with critical limb ischemia：a pilot study. Circ J 2012；76：1750-1760 – reference: 8) Matoba S, Tatsumi T, Murohara T, et al：Long-term clinical outcome after intramuscular implantation of bone marrow mononuclear cells（Therapeutic Angiogenesis by Cell Transplantation［TACT］ trial） in patients with chronic limb ischemia. Am Heart J 2008；156：1010-1018 |
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| Title | 重症虚血肢の再生医療 |
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