神経線維腫症1型患者の口蓋に発生した巨大な神経線維腫の1例

• Published in: 日本口腔外科学会雑誌 Vol. 67; no. 10; pp. 596 - 600
• Main Authors: 比嘉, 努, 比嘉, 盛敏, 狩野, 岳史, 銘苅, 泰明, 新垣, 敬一, 仲間, 錠嗣
• Format: Journal Article
• Language: Japanese
• Published: 社団法人 日本口腔外科学会 20.10.2021
• Subjects: 口蓋; 神経線維腫; 神経線維腫症1型
• ISSN: 0021-5163; 2186-1579
• DOI: 10.5794/jjoms.67.596

Neurofibromatosis type I (NF1) is a chromosomal dominant hereditary disease characterized by cafe-au-lait spots of the skin and multiple neurofibroma. Oral manifestation of NF1 is relatively infrequent. We report a rare case of huge neurofibroma arising in the palate, associated with NF1. A 39-year-old woman visited our department with the complaint of a painless mass in the hard palate. An elastic-soft swelling measuring 50 x 38 mm was found on the right palate. The tumor was excised under general anesthesia. Histopathological findings revealed neurofibroma. The tumor has not recurred, and the patient has made good progress.