化学物質の複合曝露による有害性評価の実際

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Published in環境化学 Vol. 33; no. Special_Issue; pp. s35 - s41
Main Author 石井, 聡子
Format Journal Article
LanguageJapanese
Published 一般社団法人 日本環境化学会 2023
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ISSN0917-2408
1882-5818
DOI10.5985/jec.33.s35

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Author 石井, 聡子
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References 13) EFSA (European Food Safety Authority) : Human risk assessment of multiple chemicals using component-based approaches_ A horizontal perspective. (2020), https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2020.EN-1759, 2023年2月28日現在
17) CEFIC REACH Practical Guide on Safe Use Information for Mixtures under REACH The Lead Component Identification (LCID) Methodology (2018), https://cefic.org/app/uploads/2016/03/Practical-Guide-Safe-Use-Information-for-Mixtures-under-REACH_v6-1-1.pdf, 2023年2月28日現在
18) 日本化学工業協会:JIPS混合物リスク評価のためのガイダンス (2017) ,https://www.jcia-bigdr.jp/jcia-bigdr/doc/document/JIPS_mixture_risk_guidance_201707.pdf,2023年2月28日現在
1) EFSA (European Food Safety Authority) Scientific Committee: Guidance on harmonised methodologies for human health, animal health and ecological risk assessment of combined exposure to multiple chemicals. EFSA J., 17, e05634 (2019), https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2019.5634
10) Meek, M.E.B., Boobis, A.R., Crofton, K.M., Heinemeyer, G., Raaij, M.V. and Vickers, C.: Risk assessment of combined exposure to multiple chemicals: a WHO/IPCS framework. Regul. Toxicol. Pharmacol., 60, S1-S14 (2011), https://www.sciencedirect.com/science/article/pii/S0273230011000638?via%3Dihub, 2023年2月28日現在
20) 石井聡子:化学物質リスク評価における混合物の取扱いと評価方法,「製品含有化学物質のリスク管理,情報伝達の効率化」,技術情報協会,東京 (2017
16) Seed, J., Brown, R.P., Olin, S.S. and Foran, J.A.: Chemical mixtures: Current risk assessment methodologies and future directions. Regul. Toxicol. Pharmacol., 22, 76-94 (1995
15) 環境省:平成15年度臭素系ダイオキシン等排出実態調査結果報告書 (2005) ,https://www.env.go.jp/air/report/h16-12/index.html,2023年2月28日現在
12) SCCS/SCHER/SCHENIFR (Scientific Committee on Consumer Safety/Scientific Committee on Health and Environmental Risks/Scientific Committee on Emerging and Newly Identified Health Risks) : Toxicity and Assessment of Chemical Mixtures (2012), https://ec.europa.eu/health/scientific_committees/environmental_risks/docs/scher_o_155.pdf, 2023年2月28日現在
14) 日本産業衛生学会:許容濃度等の勧告 (2022年度) ,日本産業衛生学会誌,64,253-285 (2022), https://www.sanei.or.jp/files/topics/oels/oel.pdf
19) Kaneko, K., Ishii, S., Hosohara, S., Hirata, T., Masuda, M., Murasawa, K., Yamada, A., Tadokoro, T. and Hanzawa, M.: Lead substances selection using GHS approach for the classification of mixtures: Case study of painting in the work environment. Regul. Toxicol. Pharm., 88, 273-282 (2017), https://www.sciencedirect.com/science/article/pii/S0273230017301848
7) U.S. ATSDR (Agency for Toxic Substances and Disease Registry) : Guidance Manual for the Assessment of Joint Toxic Action of Chemical Mixtures (2004), https://stacks.cdc.gov/view/cdc/6935, 2023年2月28日現在
3) Cassee, F.R., Groten, J.P., van Bladeren, P.J. and Feron, V.J.: Toxicological evaluation and risk assessment of chemical mixtures. Crit. Rev. Toxicol., 28, 78-101 (1998
11) European Commission: State of the Art Report on Mixture Toxicity: Final Report. Study Contract No. 070307/2007/485103/ETU/D.1 (2009), https://ec.europa.eu/environment/chemicals/effects/pdf/report_mixture_toxicity.pdf, 2023年2月28日現在
4) COT (Committee on Toxicity of Chemicals in Foods) : Consumer Products and the Environment. Risk assessment of Mixtures of Pesticides and Similar Substances. September 2002. FSA/0691/0902 (2002), https://cot.food.gov.uk/sites/default/files/cot/reportindexed.pdf, 2023年2月28日現在
6) Luque-Garcia, J.L., Cabezas-Sanchez, P., Anunciação, D.S. and Camara, C.: Analytical and bioanalytical approaches to unravel the selenium-mercury antagonism: a review. Anal. Chim. Acta., 801, 1-13 (2013
8) U.S. ATSDR (Agency for Toxic Substances and Disease Registry) : Framework for Assessing Health Impacts of Multiple Chemicals and Other Stressors (Update). (2018), https://www.atsdr.cdc.gov/interactionprofiles/ip-ga/ipga-p.pdf, 2023年2月28日現在
2) Bliss, C.I.: The toxicity of poisons applied jointly. Ann. Appl. Biol., 26, 585-615 (1939
5) Utgikar, V.P., Chaudhary, N., Koeniger, A., Tabak, H.H., Haines, J.R. and Govind, R.: Toxicity of metals and metal mixtures: analysis of concentration and time dependence for zinc and copper. Water Res., 38, 3651-3658 (2004
9) WHO/IPCS (World Health Organization/International Programme on Chemical Safety) : Assessment of combined exposures to multiple chemicals: report of a WHO/IPCS international workshop on aggregate/cumulative risk assessment (2009), https://apps.who.int/iris/bitstream/handle/10665/44113/9789241563833_eng.pdf?sequence=1&isAllowed=y, 2023年2月28日現在
References_xml – reference: 4) COT (Committee on Toxicity of Chemicals in Foods) : Consumer Products and the Environment. Risk assessment of Mixtures of Pesticides and Similar Substances. September 2002. FSA/0691/0902 (2002), https://cot.food.gov.uk/sites/default/files/cot/reportindexed.pdf, 2023年2月28日現在
– reference: 10) Meek, M.E.B., Boobis, A.R., Crofton, K.M., Heinemeyer, G., Raaij, M.V. and Vickers, C.: Risk assessment of combined exposure to multiple chemicals: a WHO/IPCS framework. Regul. Toxicol. Pharmacol., 60, S1-S14 (2011), https://www.sciencedirect.com/science/article/pii/S0273230011000638?via%3Dihub, 2023年2月28日現在
– reference: 20) 石井聡子:化学物質リスク評価における混合物の取扱いと評価方法,「製品含有化学物質のリスク管理,情報伝達の効率化」,技術情報協会,東京 (2017)
– reference: 12) SCCS/SCHER/SCHENIFR (Scientific Committee on Consumer Safety/Scientific Committee on Health and Environmental Risks/Scientific Committee on Emerging and Newly Identified Health Risks) : Toxicity and Assessment of Chemical Mixtures (2012), https://ec.europa.eu/health/scientific_committees/environmental_risks/docs/scher_o_155.pdf, 2023年2月28日現在
– reference: 11) European Commission: State of the Art Report on Mixture Toxicity: Final Report. Study Contract No. 070307/2007/485103/ETU/D.1 (2009), https://ec.europa.eu/environment/chemicals/effects/pdf/report_mixture_toxicity.pdf, 2023年2月28日現在
– reference: 15) 環境省:平成15年度臭素系ダイオキシン等排出実態調査結果報告書 (2005) ,https://www.env.go.jp/air/report/h16-12/index.html,2023年2月28日現在
– reference: 5) Utgikar, V.P., Chaudhary, N., Koeniger, A., Tabak, H.H., Haines, J.R. and Govind, R.: Toxicity of metals and metal mixtures: analysis of concentration and time dependence for zinc and copper. Water Res., 38, 3651-3658 (2004)
– reference: 1) EFSA (European Food Safety Authority) Scientific Committee: Guidance on harmonised methodologies for human health, animal health and ecological risk assessment of combined exposure to multiple chemicals. EFSA J., 17, e05634 (2019), https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2019.5634
– reference: 16) Seed, J., Brown, R.P., Olin, S.S. and Foran, J.A.: Chemical mixtures: Current risk assessment methodologies and future directions. Regul. Toxicol. Pharmacol., 22, 76-94 (1995)
– reference: 18) 日本化学工業協会:JIPS混合物リスク評価のためのガイダンス (2017) ,https://www.jcia-bigdr.jp/jcia-bigdr/doc/document/JIPS_mixture_risk_guidance_201707.pdf,2023年2月28日現在
– reference: 9) WHO/IPCS (World Health Organization/International Programme on Chemical Safety) : Assessment of combined exposures to multiple chemicals: report of a WHO/IPCS international workshop on aggregate/cumulative risk assessment (2009), https://apps.who.int/iris/bitstream/handle/10665/44113/9789241563833_eng.pdf?sequence=1&isAllowed=y, 2023年2月28日現在
– reference: 14) 日本産業衛生学会:許容濃度等の勧告 (2022年度) ,日本産業衛生学会誌,64,253-285 (2022), https://www.sanei.or.jp/files/topics/oels/oel.pdf
– reference: 3) Cassee, F.R., Groten, J.P., van Bladeren, P.J. and Feron, V.J.: Toxicological evaluation and risk assessment of chemical mixtures. Crit. Rev. Toxicol., 28, 78-101 (1998)
– reference: 2) Bliss, C.I.: The toxicity of poisons applied jointly. Ann. Appl. Biol., 26, 585-615 (1939)
– reference: 17) CEFIC REACH Practical Guide on Safe Use Information for Mixtures under REACH The Lead Component Identification (LCID) Methodology (2018), https://cefic.org/app/uploads/2016/03/Practical-Guide-Safe-Use-Information-for-Mixtures-under-REACH_v6-1-1.pdf, 2023年2月28日現在
– reference: 6) Luque-Garcia, J.L., Cabezas-Sanchez, P., Anunciação, D.S. and Camara, C.: Analytical and bioanalytical approaches to unravel the selenium-mercury antagonism: a review. Anal. Chim. Acta., 801, 1-13 (2013)
– reference: 8) U.S. ATSDR (Agency for Toxic Substances and Disease Registry) : Framework for Assessing Health Impacts of Multiple Chemicals and Other Stressors (Update). (2018), https://www.atsdr.cdc.gov/interactionprofiles/ip-ga/ipga-p.pdf, 2023年2月28日現在
– reference: 13) EFSA (European Food Safety Authority) : Human risk assessment of multiple chemicals using component-based approaches_ A horizontal perspective. (2020), https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/sp.efsa.2020.EN-1759, 2023年2月28日現在
– reference: 19) Kaneko, K., Ishii, S., Hosohara, S., Hirata, T., Masuda, M., Murasawa, K., Yamada, A., Tadokoro, T. and Hanzawa, M.: Lead substances selection using GHS approach for the classification of mixtures: Case study of painting in the work environment. Regul. Toxicol. Pharm., 88, 273-282 (2017), https://www.sciencedirect.com/science/article/pii/S0273230017301848
– reference: 7) U.S. ATSDR (Agency for Toxic Substances and Disease Registry) : Guidance Manual for the Assessment of Joint Toxic Action of Chemical Mixtures (2004), https://stacks.cdc.gov/view/cdc/6935, 2023年2月28日現在
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Title 化学物質の複合曝露による有害性評価の実際
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