口蓋に発生したpleomorphic lipomaの1例
A pleomorphic lipoma is a rare benign lipomatous tumor that has been defined by Enzinger as a new lipomatous entity. Pleomorphic lipoma mainly arises in the subcutaneous tissue of the neck and shoulders in elderly men, with relatively few reported cases of the tumor in the oral maxillofacial region....
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| Published in | 日本口腔外科学会雑誌 Vol. 65; no. 6; pp. 402 - 405 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
社団法人 日本口腔外科学会
20.06.2019
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0021-5163 2186-1579 |
| DOI | 10.5794/jjoms.65.402 |
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| Abstract | A pleomorphic lipoma is a rare benign lipomatous tumor that has been defined by Enzinger as a new lipomatous entity. Pleomorphic lipoma mainly arises in the subcutaneous tissue of the neck and shoulders in elderly men, with relatively few reported cases of the tumor in the oral maxillofacial region. We report a case of pleomorphic lipoma arising in the left hard palate mucosa of a 67-year-old man. The lesion was a tender, sharp and pedunculated mass measuring 7 × 7 mm. The tumor was surgically removed including the surrounding normal tissue, and the histopathological diagnosis was pleomorphic lipoma. Microscopic examination histologically revealed a subepithelial admixture of mature adipose tissue and overgrowth of fibrous tissue, scattered with CD34-positive large and multinucleated cells. Four years after surgery, the patient remains recurrence-free and has a good clinical course. |
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| AbstractList | A pleomorphic lipoma is a rare benign lipomatous tumor that has been defined by Enzinger as a new lipomatous entity. Pleomorphic lipoma mainly arises in the subcutaneous tissue of the neck and shoulders in elderly men, with relatively few reported cases of the tumor in the oral maxillofacial region. We report a case of pleomorphic lipoma arising in the left hard palate mucosa of a 67-year-old man. The lesion was a tender, sharp and pedunculated mass measuring 7 × 7 mm. The tumor was surgically removed including the surrounding normal tissue, and the histopathological diagnosis was pleomorphic lipoma. Microscopic examination histologically revealed a subepithelial admixture of mature adipose tissue and overgrowth of fibrous tissue, scattered with CD34-positive large and multinucleated cells. Four years after surgery, the patient remains recurrence-free and has a good clinical course. |
| Author | 杉山, 尚希 寺田, 知加 里村, 一人 戸田, (徳山) 麗子 梅木, 泰親 佐藤, 徹 |
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| References | 2) Shmookler BM and Enzinger FM : Pleomorphic lipoma : A benign tumor simulating liposarcoma. A clinicopathologic analysis of 48 cases. Cancer 47: 126-133, 1981. 27) Guillou L, Dehon A, et al : Pleomorphic lipoma of the tongue : case report and literature review. J Otolaryngol 15: 313-316, 1986. 19) 福山圭子， 掛水夏恵， 他：pleomorphic lipoma．皮病診療 24: 517-520, 2002. 11) 中西純夫， 野村日出夫， 他：Pleomorphic Lipomaの2例．病理と臨床 1: 780-785, 1983. 23) 庄野佳孝， 岡部 寛， 他：Pleomorphic Lipomaの1例．日形会誌 35: 682-687, 2015. 28) Prado FO, Ito FA, et al : Pleomorphic lipoma of the face : case report. Oral Dis 12: 73-76, 2006. 15) 福井義尚， 大園誠一郎， 他： 後腹膜pleomorphic lipomaの1例．泌紀 37: 373-376, 1991. 21) 尾﨑絵美， 村上隆一， 他：再発をきたした頰部Pleomorphic Lipomaの1例．日頭顎顔会誌 26: 371-375, 2010. 25) Perrotti V, Rubini C, et al : Pleomorphic lipoma of the oral cavity. Report of a case. Minerva Stomatol 55: 321-325, 2006. 5) 上野万里， 泉 美貴， 他：背部皮下腫瘤の1例．日皮病理組織会誌 18: 14-17, 2002. 26) Atik E, Usta U, et al : Pleomorphic lipoma of the tongue. Otolaryngol Head Neck Surg 126: 430-431, 2002. 3) 野澤 浩， 渡邊伸也， 他：頰部粘膜部に発生した多形性脂肪腫の1例．日口外誌 59: 781-785, 2013. 9) 印藤昌彦， 檜原理子， 他：Pleomorphic Lipomaの1例．皮膚臨床 46: 943-945, 2004. 22) 原田勝久， 岡村一樹， 他：精索内pleomorphic lipomaの1例．日臨外会誌 73: 1551-1555, 2012. 20) 黒田正義：耳後部に生じたPleomorphic lipomaの1例．日形会誌 30: 556-558, 2010. 8) Weiss SW and Goldblum JR : Enzinger and Weiss’s Soft Tissue Tumors. Mosby Elsevier, Philadelphia, 2008. 24) Vecchio G, Amico P, et al : Spindle cell/Pleomorphic Lipoma of the Oral Cavity. J Craniofac Surg 20: 1992-1994, 2009. 13) 平敷貴也， 石倉直敬， 他：頰部に生じたpleomorphic lipomaの1例．形成外科 33: 1105-1109, 1990. 17) 山本惣一郎， 横崎 宏， 他：左肩甲部に発生した多形性脂肪腫の1例．広島医 49: 985-986, 1996. 1) Enzinger FM : Benign lipomatous tumors simulating a sarcoma. In Martin RG, Ayala AG eds ; Management of Primary Bone and Soft Tissue Tumors. Year Book Medical Publishers, Inc, Chicago, 1977, p11-24. 6) 木村俊介， 足立守安， 他：顎下部から頸部に及ぶ巨大なpleomorphic lipomaの1例．日口外誌 61: 31-35, 2015. 7) 酒巻治彦， 吉沢夏人， 他：Pleomorphic Lipomaの1例．関東整災外会誌 19: 355-357, 1988. 10) 上野泰志， 山之内宏一， 他： 眼窩Pleomorphic Lipomaの1例．日眼紀 33: 1493-1504, 1982. 12) 林徳真吉， 津田暢夫， 他：手掌に生じたpleomorphic lipomaの1例 spindle cell lipomaとの比較．癌の臨 35: 437-441, 1989. 4) Miettinen MM and Mandahl N : Spindle cell lipoma/pleomorphic lipoma. In Fletcher CDM, Unni KK, et al, eds ; WHO classification of tumors, Pathology and genetics tumors of soft tissue and bone, IARC Press, Lyon, 2002, p31-32. 14) 田中孝男， 清水信晶， 他：結膜下に多形性脂肪腫Pleomorphic lipomaが認められた一症例．眼臨医報 85: 736-738, 1991. 18) Lee Sang Goang, Ohtoshi Eriko, 他：多形性脂肪腫例．皮紀 93: 15-17, 1998. 16) 前川武男， 巾 尊宣， 他：後腹膜に発生したpleomorphic lipomaの1例．日臨外会誌 56: 1235-1239, 1995. 30) 佐藤敏秀， 五嶋孝博， 他：急速な増大のために高分化型脂肪肉腫との鑑別を要した項部Spindle cell lipomaの1例．日外科系連会誌 39: 1012-1017, 2014. 29) 岩崎 宏：脂肪性腫瘍−特に異型脂肪腫様腫瘍と脱分化脂肪肉腫の多様性について−．病理と臨 22: 120-126, 2004. |
| References_xml | – reference: 23) 庄野佳孝， 岡部 寛， 他：Pleomorphic Lipomaの1例．日形会誌 35: 682-687, 2015. – reference: 14) 田中孝男， 清水信晶， 他：結膜下に多形性脂肪腫Pleomorphic lipomaが認められた一症例．眼臨医報 85: 736-738, 1991. – reference: 7) 酒巻治彦， 吉沢夏人， 他：Pleomorphic Lipomaの1例．関東整災外会誌 19: 355-357, 1988. – reference: 20) 黒田正義：耳後部に生じたPleomorphic lipomaの1例．日形会誌 30: 556-558, 2010. – reference: 26) Atik E, Usta U, et al : Pleomorphic lipoma of the tongue. Otolaryngol Head Neck Surg 126: 430-431, 2002. – reference: 6) 木村俊介， 足立守安， 他：顎下部から頸部に及ぶ巨大なpleomorphic lipomaの1例．日口外誌 61: 31-35, 2015. – reference: 15) 福井義尚， 大園誠一郎， 他： 後腹膜pleomorphic lipomaの1例．泌紀 37: 373-376, 1991. – reference: 30) 佐藤敏秀， 五嶋孝博， 他：急速な増大のために高分化型脂肪肉腫との鑑別を要した項部Spindle cell lipomaの1例．日外科系連会誌 39: 1012-1017, 2014. – reference: 25) Perrotti V, Rubini C, et al : Pleomorphic lipoma of the oral cavity. Report of a case. Minerva Stomatol 55: 321-325, 2006. – reference: 19) 福山圭子， 掛水夏恵， 他：pleomorphic lipoma．皮病診療 24: 517-520, 2002. – reference: 27) Guillou L, Dehon A, et al : Pleomorphic lipoma of the tongue : case report and literature review. J Otolaryngol 15: 313-316, 1986. – reference: 18) Lee Sang Goang, Ohtoshi Eriko, 他：多形性脂肪腫例．皮紀 93: 15-17, 1998. – reference: 29) 岩崎 宏：脂肪性腫瘍−特に異型脂肪腫様腫瘍と脱分化脂肪肉腫の多様性について−．病理と臨 22: 120-126, 2004. – reference: 8) Weiss SW and Goldblum JR : Enzinger and Weiss’s Soft Tissue Tumors. Mosby Elsevier, Philadelphia, 2008. – reference: 21) 尾﨑絵美， 村上隆一， 他：再発をきたした頰部Pleomorphic Lipomaの1例．日頭顎顔会誌 26: 371-375, 2010. – reference: 5) 上野万里， 泉 美貴， 他：背部皮下腫瘤の1例．日皮病理組織会誌 18: 14-17, 2002. – reference: 28) Prado FO, Ito FA, et al : Pleomorphic lipoma of the face : case report. Oral Dis 12: 73-76, 2006. – reference: 1) Enzinger FM : Benign lipomatous tumors simulating a sarcoma. In Martin RG, Ayala AG eds ; Management of Primary Bone and Soft Tissue Tumors. Year Book Medical Publishers, Inc, Chicago, 1977, p11-24. – reference: 2) Shmookler BM and Enzinger FM : Pleomorphic lipoma : A benign tumor simulating liposarcoma. A clinicopathologic analysis of 48 cases. Cancer 47: 126-133, 1981. – reference: 11) 中西純夫， 野村日出夫， 他：Pleomorphic Lipomaの2例．病理と臨床 1: 780-785, 1983. – reference: 16) 前川武男， 巾 尊宣， 他：後腹膜に発生したpleomorphic lipomaの1例．日臨外会誌 56: 1235-1239, 1995. – reference: 24) Vecchio G, Amico P, et al : Spindle cell/Pleomorphic Lipoma of the Oral Cavity. J Craniofac Surg 20: 1992-1994, 2009. – reference: 4) Miettinen MM and Mandahl N : Spindle cell lipoma/pleomorphic lipoma. In Fletcher CDM, Unni KK, et al, eds ; WHO classification of tumors, Pathology and genetics tumors of soft tissue and bone, IARC Press, Lyon, 2002, p31-32. – reference: 9) 印藤昌彦， 檜原理子， 他：Pleomorphic Lipomaの1例．皮膚臨床 46: 943-945, 2004. – reference: 13) 平敷貴也， 石倉直敬， 他：頰部に生じたpleomorphic lipomaの1例．形成外科 33: 1105-1109, 1990. – reference: 22) 原田勝久， 岡村一樹， 他：精索内pleomorphic lipomaの1例．日臨外会誌 73: 1551-1555, 2012. – reference: 3) 野澤 浩， 渡邊伸也， 他：頰部粘膜部に発生した多形性脂肪腫の1例．日口外誌 59: 781-785, 2013. – reference: 10) 上野泰志， 山之内宏一， 他： 眼窩Pleomorphic Lipomaの1例．日眼紀 33: 1493-1504, 1982. – reference: 17) 山本惣一郎， 横崎 宏， 他：左肩甲部に発生した多形性脂肪腫の1例．広島医 49: 985-986, 1996. – reference: 12) 林徳真吉， 津田暢夫， 他：手掌に生じたpleomorphic lipomaの1例 spindle cell lipomaとの比較．癌の臨 35: 437-441, 1989. |
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| Title | 口蓋に発生したpleomorphic lipomaの1例 |
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