下顎骨に生じた骨芽細胞腫の1例
Osteoblastoma is a rare tumor that accounts for less than 1% of all bone tumors and is characterized by the development of osteoblasts and osteoid tissue. It is classified as an intermediate type tumor with local aggressiveness. The tumor mass is usually larger than 2 cm, and there have been no repo...
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| Published in | 日本口腔外科学会雑誌 Vol. 63; no. 8; pp. 388 - 393 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
社団法人 日本口腔外科学会
20.08.2017
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0021-5163 2186-1579 |
| DOI | 10.5794/jjoms.63.388 |
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| Abstract | Osteoblastoma is a rare tumor that accounts for less than 1% of all bone tumors and is characterized by the development of osteoblasts and osteoid tissue. It is classified as an intermediate type tumor with local aggressiveness. The tumor mass is usually larger than 2 cm, and there have been no reports of large osteoblastomas in Japan in recent years. We report the case of a large osteoblastoma, including a description of the previously obtained X-ray films. The patient was a 22-year-old man who visited our hospital with a chief complaint of swelling of the left side of the mandible. The tumor measured 40×40×30 mm, and X-ray films showed a radiolucent image including a calcified body with a clear margin. Osteoblastoma was diagnosed on the basis of two biopsies. Segmental mandibulectomy was performed with the patient under general anesthesia. There has been no recurrence after the operation, and the patient is making good progress. A panoramic X-ray film taken 7 years ago (at 15 years of age) revealed slight bone resorption resembling periodontitis in the region where the tumor had developed. Consequently, there was a high probability that this X-ray film indicated an early stage of this tumor. |
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| AbstractList | Osteoblastoma is a rare tumor that accounts for less than 1% of all bone tumors and is characterized by the development of osteoblasts and osteoid tissue. It is classified as an intermediate type tumor with local aggressiveness. The tumor mass is usually larger than 2 cm, and there have been no reports of large osteoblastomas in Japan in recent years. We report the case of a large osteoblastoma, including a description of the previously obtained X-ray films. The patient was a 22-year-old man who visited our hospital with a chief complaint of swelling of the left side of the mandible. The tumor measured 40×40×30 mm, and X-ray films showed a radiolucent image including a calcified body with a clear margin. Osteoblastoma was diagnosed on the basis of two biopsies. Segmental mandibulectomy was performed with the patient under general anesthesia. There has been no recurrence after the operation, and the patient is making good progress. A panoramic X-ray film taken 7 years ago (at 15 years of age) revealed slight bone resorption resembling periodontitis in the region where the tumor had developed. Consequently, there was a high probability that this X-ray film indicated an early stage of this tumor. |
| Author | 中村, 典史 嶋, 香織 豊留, 宗一郎 石畑, 清秀 野添, 悦郎 大河内, 孝子 |
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| References | 10) Kulkarni MM, Shah AK, et al : Aggressive osteoblastoma of the mandible: a case report. International Journal of Contemporary Dentistry 2: 135-138, 2011. 5) 北島正一朗，安井昭夫，他：小児の下顎骨に発生した骨芽細胞腫の1例．日口外誌 61: 42-46, 2015. 13) Caltabiano R, Serra A, et al : A rare location of benign osteoblastoma: case study and review of the literature. Eur Rev Med Pharmacol Sci 16: 1891-1894, 2012. 16) Kaur H, Verma S, et al : Aggressive osteoblastoma of the mandible: a diagnostic dilemma. Dent Res J 9: 334-337, 2012. 6) Manjunatha BS, Sunit P, et al : Osteoblastoma of the jaws: report of a case and review of literature. Clin Pract 1: 256-258, 2011. 7) Wozniak AW, Nowaczyk MT, et al : Malignant transformation of an osteoblastoma of the mandible: case report and review of the literature. Eur Arch Otorhinolaryngol 267: 845-849, 2010. 4) 石田 剛：骨芽細胞腫；骨腫瘍の病理．第1版，文光堂，東京，2012，46-54頁 11) Arantes M, Resende M, et al : Benign osteoblastoma of the sphenoid bone. Skull Base 19: 437-441, 2009. 12) Dabholkar JP, Vora K, et al : Benign jaw tumors. Indian J Otolaryngol Head Neck Surg 61: 240-244, 2009. 27) 石井宏昭，相田 聡，他：下顎骨に発生した骨芽細胞腫の1例．日口外誌 42: 1124-1126, 1996. 21) Lypka MA, Goos RR, et al : Aggressive osteoblastoma of the mandible. Int J Oral Maxillofac Surg 37: 675-678, 2008. 25) 古館 厚，丸茂町子，他：下顎良性骨芽細胞腫の1例．口科誌 33: 140-149, 1984. 26) 伊藤輝夫，松瀬洋一，他：珍しいBenign Osteoblastomaの再発例について．口科誌 20: 847-855, 1971. 2) Andrea CE, Bridge JA, et al : Osteoblastoma. In Fletcher DM, Bridge JA, eds ; WHO Classification of Tumours of Soft Tissue and Bone. IARC Press, Lyon, 2013, p240-280. 1) 豊澤 悟：良性非上皮性腫瘍．下野正基，高田 隆；新口腔病理学．第1版，医歯薬出版，東京，2008，224, 230-235頁 18) Bokhari K, Hameed MS, et al : Benign osteoblastoma involving maxilla: a case report and review of the literature. Case Rep Dent 2012: 1-4, 2012. 3) Jundt G, Gertoni F, et al : Benign tumours of bone and cartilage. In Barnes L, Eveson JW, eds ; WHO Classification of Tumours, Pathology and Genetics of Head and Neck Tumours. IARC Press, Lyon, 2005, p55-56. 14) Strobel K, Merwald M, et al : Osteoblastoma of the mandible mimicking osteosarcoma in FDG PET/CT imaging. Clin Nucl Med 38: 143-144, 2013. 19) Shah S, Kim JE, et al : Recurrent osteoblastoma of the maxilla. Dentomaxillofac Radiol 42: 20100263, 2013. 24) 藤井崇史，植野高章，他：下顎骨に発生した骨芽細胞腫の1例．日口外誌 48: 32-35, 2002. 23) 平塚博義，山本悦秀，他：下顎骨に発生した良性骨芽細胞腫の1例．日口外誌 28: 51-56, 1982. 17) Mahafan A, Kumar P, et al : Osteoblastoma in the retromolar region - report of an unusual case and review of literature. J Maxillofac Oral Surg 12: 338-340, 2013. 20) Harrington C, Accurso BT, et al : Aggressive osteoblastoma of the maxilla: a case report and review of the literature. Head and Neck Pathol 5: 165-170, 2011. 15) Lin B, Cai ZG, et al : Osteoblastoma of the maxilla and mandible: a report of 2 cases and literature review. Chin J Dent Res 15: 153-158, 2012. 8) Vinuth DP, Agarwal P, et al : A large multifocal aggressive osteoblastoma of mandible: an immunohistochemistry case study report. J Dent Res Dent Clin Dent Prospect 8: 51-55, 2014. 9) Saikhedkar R, Wanjari S, et al : Osteoblastoma involving maxilla: an unusual case report with review of literature. J Orofac Sci 2: 53-57, 2010. 22) 岩本 忍，北村昌也，他：下顎骨に発生した良性骨芽細胞腫の1症例．日口外誌 32: 285-290, 1986. |
| References_xml | – reference: 21) Lypka MA, Goos RR, et al : Aggressive osteoblastoma of the mandible. Int J Oral Maxillofac Surg 37: 675-678, 2008. – reference: 2) Andrea CE, Bridge JA, et al : Osteoblastoma. In Fletcher DM, Bridge JA, eds ; WHO Classification of Tumours of Soft Tissue and Bone. IARC Press, Lyon, 2013, p240-280. – reference: 27) 石井宏昭，相田 聡，他：下顎骨に発生した骨芽細胞腫の1例．日口外誌 42: 1124-1126, 1996. – reference: 16) Kaur H, Verma S, et al : Aggressive osteoblastoma of the mandible: a diagnostic dilemma. Dent Res J 9: 334-337, 2012. – reference: 9) Saikhedkar R, Wanjari S, et al : Osteoblastoma involving maxilla: an unusual case report with review of literature. J Orofac Sci 2: 53-57, 2010. – reference: 5) 北島正一朗，安井昭夫，他：小児の下顎骨に発生した骨芽細胞腫の1例．日口外誌 61: 42-46, 2015. – reference: 20) Harrington C, Accurso BT, et al : Aggressive osteoblastoma of the maxilla: a case report and review of the literature. Head and Neck Pathol 5: 165-170, 2011. – reference: 18) Bokhari K, Hameed MS, et al : Benign osteoblastoma involving maxilla: a case report and review of the literature. Case Rep Dent 2012: 1-4, 2012. – reference: 13) Caltabiano R, Serra A, et al : A rare location of benign osteoblastoma: case study and review of the literature. Eur Rev Med Pharmacol Sci 16: 1891-1894, 2012. – reference: 22) 岩本 忍，北村昌也，他：下顎骨に発生した良性骨芽細胞腫の1症例．日口外誌 32: 285-290, 1986. – reference: 25) 古館 厚，丸茂町子，他：下顎良性骨芽細胞腫の1例．口科誌 33: 140-149, 1984. – reference: 23) 平塚博義，山本悦秀，他：下顎骨に発生した良性骨芽細胞腫の1例．日口外誌 28: 51-56, 1982. – reference: 26) 伊藤輝夫，松瀬洋一，他：珍しいBenign Osteoblastomaの再発例について．口科誌 20: 847-855, 1971. – reference: 7) Wozniak AW, Nowaczyk MT, et al : Malignant transformation of an osteoblastoma of the mandible: case report and review of the literature. Eur Arch Otorhinolaryngol 267: 845-849, 2010. – reference: 19) Shah S, Kim JE, et al : Recurrent osteoblastoma of the maxilla. Dentomaxillofac Radiol 42: 20100263, 2013. – reference: 15) Lin B, Cai ZG, et al : Osteoblastoma of the maxilla and mandible: a report of 2 cases and literature review. Chin J Dent Res 15: 153-158, 2012. – reference: 11) Arantes M, Resende M, et al : Benign osteoblastoma of the sphenoid bone. Skull Base 19: 437-441, 2009. – reference: 14) Strobel K, Merwald M, et al : Osteoblastoma of the mandible mimicking osteosarcoma in FDG PET/CT imaging. Clin Nucl Med 38: 143-144, 2013. – reference: 24) 藤井崇史，植野高章，他：下顎骨に発生した骨芽細胞腫の1例．日口外誌 48: 32-35, 2002. – reference: 4) 石田 剛：骨芽細胞腫；骨腫瘍の病理．第1版，文光堂，東京，2012，46-54頁． – reference: 8) Vinuth DP, Agarwal P, et al : A large multifocal aggressive osteoblastoma of mandible: an immunohistochemistry case study report. J Dent Res Dent Clin Dent Prospect 8: 51-55, 2014. – reference: 10) Kulkarni MM, Shah AK, et al : Aggressive osteoblastoma of the mandible: a case report. International Journal of Contemporary Dentistry 2: 135-138, 2011. – reference: 17) Mahafan A, Kumar P, et al : Osteoblastoma in the retromolar region - report of an unusual case and review of literature. J Maxillofac Oral Surg 12: 338-340, 2013. – reference: 6) Manjunatha BS, Sunit P, et al : Osteoblastoma of the jaws: report of a case and review of literature. Clin Pract 1: 256-258, 2011. – reference: 3) Jundt G, Gertoni F, et al : Benign tumours of bone and cartilage. In Barnes L, Eveson JW, eds ; WHO Classification of Tumours, Pathology and Genetics of Head and Neck Tumours. IARC Press, Lyon, 2005, p55-56. – reference: 12) Dabholkar JP, Vora K, et al : Benign jaw tumors. Indian J Otolaryngol Head Neck Surg 61: 240-244, 2009. – reference: 1) 豊澤 悟：良性非上皮性腫瘍．下野正基，高田 隆；新口腔病理学．第1版，医歯薬出版，東京，2008，224, 230-235頁． |
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| SubjectTerms | 下顎区域切除術 骨芽細胞腫 |
| Title | 下顎骨に生じた骨芽細胞腫の1例 |
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