口底部に発生した炎症性筋線維芽細胞腫の1例
Inflammatory myofibroblastic tumors (IMT) are spindle cell proliferations with a characteristic fibro-inflammatory appearance, originally referred to as an inflammatory pseudotumors or plasma cell granulomas. We report a case of IMT in the floor of the mouth of a 41-year old female. The patient had...
Saved in:
| Published in | 日本口腔外科学会雑誌 Vol. 67; no. 7; pp. 433 - 437 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
社団法人 日本口腔外科学会
20.07.2021
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0021-5163 2186-1579 |
| DOI | 10.5794/jjoms.67.433 |
Cover
| Abstract | Inflammatory myofibroblastic tumors (IMT) are spindle cell proliferations with a characteristic fibro-inflammatory appearance, originally referred to as an inflammatory pseudotumors or plasma cell granulomas. We report a case of IMT in the floor of the mouth of a 41-year old female. The patient had a tumor in the floor of her mouth, measuring 35 × 30 × 20 mm. Magnetic resonance imaging (MRI) showed a lesion with high signal intensity on T1-weighted images. We performed resection under local anesthesia. Histological examination of the surgically removed lesion showed that the proliferative spindle cell was found inside the lipoma. There was no evidence of recurrence after five years. IMT are usually benign, however there are also reports of recurrence and malignant transformation. Careful long-term follow-up using MRI etc. is thought to be necessary. |
|---|---|
| AbstractList | Inflammatory myofibroblastic tumors (IMT) are spindle cell proliferations with a characteristic fibro-inflammatory appearance, originally referred to as an inflammatory pseudotumors or plasma cell granulomas. We report a case of IMT in the floor of the mouth of a 41-year old female. The patient had a tumor in the floor of her mouth, measuring 35 × 30 × 20 mm. Magnetic resonance imaging (MRI) showed a lesion with high signal intensity on T1-weighted images. We performed resection under local anesthesia. Histological examination of the surgically removed lesion showed that the proliferative spindle cell was found inside the lipoma. There was no evidence of recurrence after five years. IMT are usually benign, however there are also reports of recurrence and malignant transformation. Careful long-term follow-up using MRI etc. is thought to be necessary. |
| Author | 松坂, 賢一 橋本, 和彦 伊藤, 和宏 片倉, 朗 別所, 央城 菅原, 圭亮 |
| Author_xml | – sequence: 1 fullname: 菅原, 圭亮 organization: 東京歯科大学口腔病態外科学講座 – sequence: 1 fullname: 伊藤, 和宏 organization: 東京歯科大学口腔病態外科学講座 – sequence: 1 fullname: 橋本, 和彦 organization: 東京歯科大学市川総合病院臨床検査科病理 – sequence: 1 fullname: 片倉, 朗 organization: 東京歯科大学口腔病態外科学講座 – sequence: 1 fullname: 別所, 央城 organization: 東京歯科大学口腔病態外科学講座 – sequence: 1 fullname: 松坂, 賢一 organization: 東京歯科大学臨床検査病理学講座 |
| BookMark | eNo9kEtLw0AAhBepYKy9-TdSd7PZ3eQgIsUXFLzoedkku5rQhyS9eDMWEVrQi1L0YA8eFErFgygU9M_EuvFfGB94mTl8w8DMPCi12i0JwCKCVcJceymK2s2kSlnVxngGGBZyqIkKUgIGhBYyCaJ4DlSSJPQgJA5zGaYGWJ6e304nl5_d-ywd6auJvhhm6SBLh_r4TA9OP47u9LivX6718zjvveqnx7x7k5-MsvQBvb_1F8CsEo1EVv68DHbX13Zqm2Z9e2Ortlo3IwtDYiqHQdv3hIOIoAFUls8c5QdEBcoWvme5SroUYUk9JRnE0FMIIccSRTCgRGFcBiu_vVHSEXuSH8RhU8SHXMSd0G9I_rOdU8bZtxQH_BN_X8Q8EvgLpcts0g |
| ContentType | Journal Article |
| Copyright | 2021 社団法人 日本口腔外科学会 |
| Copyright_xml | – notice: 2021 社団法人 日本口腔外科学会 |
| DOI | 10.5794/jjoms.67.433 |
| DatabaseTitleList | |
| DeliveryMethod | fulltext_linktorsrc |
| EISSN | 2186-1579 |
| EndPage | 437 |
| ExternalDocumentID | article_jjoms_67_7_67_433_article_char_ja |
| GroupedDBID | ALMA_UNASSIGNED_HOLDINGS F5P JSF KQ8 RJT |
| ID | FETCH-LOGICAL-j2305-f8704cba815a6d0f2c78fcd5fdf4acb29fe9613e6bfe7030bf11182af2cd65f33 |
| ISSN | 0021-5163 |
| IngestDate | Wed Sep 03 06:31:02 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | true |
| Issue | 7 |
| Language | Japanese |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-j2305-f8704cba815a6d0f2c78fcd5fdf4acb29fe9613e6bfe7030bf11182af2cd65f33 |
| OpenAccessLink | https://www.jstage.jst.go.jp/article/jjoms/67/7/67_433/_article/-char/ja |
| PageCount | 5 |
| ParticipantIDs | jstage_primary_article_jjoms_67_7_67_433_article_char_ja |
| PublicationCentury | 2000 |
| PublicationDate | 2021/07/20 |
| PublicationDateYYYYMMDD | 2021-07-20 |
| PublicationDate_xml | – month: 07 year: 2021 text: 2021/07/20 day: 20 |
| PublicationDecade | 2020 |
| PublicationTitle | 日本口腔外科学会雑誌 |
| PublicationTitleAlternate | 日口外誌 |
| PublicationYear | 2021 |
| Publisher | 社団法人 日本口腔外科学会 |
| Publisher_xml | – name: 社団法人 日本口腔外科学会 |
| References | 5) Araki M, Hashimoto K, et al : Plasma cell Granuloma with severe cortical bone destruction of the mandible appearing as a malignant lesion – a case report. Oral Radiol 18: 45-51, 2002. 17) 篠原珠緒， 渡邊 敦， 他：腫瘍生検の染色体転座の同定によって診断確定された炎症性筋線維芽細胞腫の1例．日小児血がん会誌 53: 289-293, 2016. 8) Satomi T, Watanabe M, et al : A successfully treated inflammatory myofibroblastic tumor of the mandible with long-term follow-up and review of the literature. Med Mol Morphol 43: 185-191, 2010. 15) Griffin CA, Hawkins AL, et al : Recurrent involvement of 2p23 in inflammatory myofibroblastic tumor. Cancer Res 59: 2776-2780, 1999. 23) 末次彩子， 山元英崇， 他：急速に進行した炎症性筋線維芽細胞腫の1例．日呼吸会誌 47: 1156-1159, 2009. 4) Ide F, Shimoyama T, et al : Inflammatory pseudotumor in the mandibular retromolar region. J Oral Pathol Med 27: 508-510, 1998. 9) 青田桂子: 下顎骨に発生した炎症性筋線維芽細胞性腫瘍の1例．日口外誌 51: 89-92, 2005. 14) Coffin CM, Humphrey PA, et al : Extrapulmonary inflammatory myofibroblastic tumor: A clinical and pathological survey: Semin Diagn Pathol. 15: 85-101, 1998. 16) LaVigne AW, Meredith DM, et al : Treatment-refractory ALK-positive inflammatory myofibroblastic tumour of the oral cavity. BMJ Case Reports. doi: 10.1136/bcr-2017-221553, 2018. 22) 寺尾恭一， 藤原良平， 他：診断に苦慮した上顎炎症性線維肉腫の1例．頭頸部外 23: 317-321, 2014. 21) AlKindi MG : A rare case of inflammatory myofibroblastic tumor of the mandible mimicking a malignant tumor. Saudi Dent J 29: 36-40, 2017. 19) 市原明子：12年後に再切除した腹腔内筋線維芽細胞性腫瘍の1例．日臨外会誌 72: 1579-1583, 2011. 1) Pettinato G, Manivel JC, et al : Inflammatory myofibroblastic tumor (plasma cell granuloma). Clinicopathologic study of 20 cases with immunohistochemical and ultrastructural observation. Am J Clin Pathol 94: 538-546, 1990. 20) Korlepara R, Guttikonda VR, et al : Inflammatory myofibroblastic tumor of mandible: A rare case report and review of literature. J Oral Maxillofac Pathol 21: 136-139, 2017. 3) Inui M, Tagawa T, et al : Inflammatory pseudotumor in the submandibular region. J Oral Pathol Med 27: 333-337, 1993. 10) 井上博文， 藤田 勝， 他：炎症性筋線維芽細胞性腫瘍の一例．日臨細胞会岡山会誌 24: 24-25, 2005. 24) Bieselli R, Ferlini C, et al : Inflammatory myofiblastic tumor (inflammatory pseudotumor): DNA flow cytometric analysis of nine pediatric cases. Cancer 77: 778-784, 1996. 12) 橋本 洋：炎症性筋線維芽細胞性腫瘍および炎症性線維肉腫：炎症性偽腫瘍の中での位置付け．病理と臨床 18: 95-101, 2000. 2) Coffin CM, Watterson J, et al : Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor): A clinicopathologic and immunohistochemical study of 84 cases.Am j Surg Pathol 19: 859-872, 1995. 6) 伊藤 章， 石橋美樹， 他：下顎骨に発生したinflammatory myofibroblastic tumorの1例．日口外誌 53: 435-438, 2007. 11) Ide F, Shimoyama T, et al : Sclerosing inflammatory myofibroblastic tumour of the tongue: animmunohistochemical and ultrastructual study. Oral Oncology 36: 300-304, 2000. 13) 金子直征， 三浦 康， 他: 腹壁に発生した炎症性筋線維芽細胞性腫瘍の1例. 日臨外会誌 68: 2092-2098, 2007. 7) 里見貴史， 松田憲一， 他：13歳女児の下顎に発生した炎症性筋線維芽細胞性腫瘍の1例．小児口外 19: 35-39, 2009. 18) 辻 敏克， 芝原一繁， 他：胸壁皮下に発生した炎症性筋線維芽細胞腫の1例．日臨外会誌 75: 911-916, 2014. |
| References_xml | – reference: 6) 伊藤 章， 石橋美樹， 他：下顎骨に発生したinflammatory myofibroblastic tumorの1例．日口外誌 53: 435-438, 2007. – reference: 5) Araki M, Hashimoto K, et al : Plasma cell Granuloma with severe cortical bone destruction of the mandible appearing as a malignant lesion – a case report. Oral Radiol 18: 45-51, 2002. – reference: 19) 市原明子：12年後に再切除した腹腔内筋線維芽細胞性腫瘍の1例．日臨外会誌 72: 1579-1583, 2011. – reference: 10) 井上博文， 藤田 勝， 他：炎症性筋線維芽細胞性腫瘍の一例．日臨細胞会岡山会誌 24: 24-25, 2005. – reference: 17) 篠原珠緒， 渡邊 敦， 他：腫瘍生検の染色体転座の同定によって診断確定された炎症性筋線維芽細胞腫の1例．日小児血がん会誌 53: 289-293, 2016. – reference: 20) Korlepara R, Guttikonda VR, et al : Inflammatory myofibroblastic tumor of mandible: A rare case report and review of literature. J Oral Maxillofac Pathol 21: 136-139, 2017. – reference: 11) Ide F, Shimoyama T, et al : Sclerosing inflammatory myofibroblastic tumour of the tongue: animmunohistochemical and ultrastructual study. Oral Oncology 36: 300-304, 2000. – reference: 7) 里見貴史， 松田憲一， 他：13歳女児の下顎に発生した炎症性筋線維芽細胞性腫瘍の1例．小児口外 19: 35-39, 2009. – reference: 2) Coffin CM, Watterson J, et al : Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor): A clinicopathologic and immunohistochemical study of 84 cases.Am j Surg Pathol 19: 859-872, 1995. – reference: 3) Inui M, Tagawa T, et al : Inflammatory pseudotumor in the submandibular region. J Oral Pathol Med 27: 333-337, 1993. – reference: 4) Ide F, Shimoyama T, et al : Inflammatory pseudotumor in the mandibular retromolar region. J Oral Pathol Med 27: 508-510, 1998. – reference: 9) 青田桂子: 下顎骨に発生した炎症性筋線維芽細胞性腫瘍の1例．日口外誌 51: 89-92, 2005. – reference: 24) Bieselli R, Ferlini C, et al : Inflammatory myofiblastic tumor (inflammatory pseudotumor): DNA flow cytometric analysis of nine pediatric cases. Cancer 77: 778-784, 1996. – reference: 15) Griffin CA, Hawkins AL, et al : Recurrent involvement of 2p23 in inflammatory myofibroblastic tumor. Cancer Res 59: 2776-2780, 1999. – reference: 14) Coffin CM, Humphrey PA, et al : Extrapulmonary inflammatory myofibroblastic tumor: A clinical and pathological survey: Semin Diagn Pathol. 15: 85-101, 1998. – reference: 21) AlKindi MG : A rare case of inflammatory myofibroblastic tumor of the mandible mimicking a malignant tumor. Saudi Dent J 29: 36-40, 2017. – reference: 23) 末次彩子， 山元英崇， 他：急速に進行した炎症性筋線維芽細胞腫の1例．日呼吸会誌 47: 1156-1159, 2009. – reference: 22) 寺尾恭一， 藤原良平， 他：診断に苦慮した上顎炎症性線維肉腫の1例．頭頸部外 23: 317-321, 2014. – reference: 8) Satomi T, Watanabe M, et al : A successfully treated inflammatory myofibroblastic tumor of the mandible with long-term follow-up and review of the literature. Med Mol Morphol 43: 185-191, 2010. – reference: 16) LaVigne AW, Meredith DM, et al : Treatment-refractory ALK-positive inflammatory myofibroblastic tumour of the oral cavity. BMJ Case Reports. doi: 10.1136/bcr-2017-221553, 2018. – reference: 13) 金子直征， 三浦 康， 他: 腹壁に発生した炎症性筋線維芽細胞性腫瘍の1例. 日臨外会誌 68: 2092-2098, 2007. – reference: 1) Pettinato G, Manivel JC, et al : Inflammatory myofibroblastic tumor (plasma cell granuloma). Clinicopathologic study of 20 cases with immunohistochemical and ultrastructural observation. Am J Clin Pathol 94: 538-546, 1990. – reference: 18) 辻 敏克， 芝原一繁， 他：胸壁皮下に発生した炎症性筋線維芽細胞腫の1例．日臨外会誌 75: 911-916, 2014. – reference: 12) 橋本 洋：炎症性筋線維芽細胞性腫瘍および炎症性線維肉腫：炎症性偽腫瘍の中での位置付け．病理と臨床 18: 95-101, 2000. |
| SSID | ssib005879736 ssib058493840 ssj0001742264 ssib000940266 |
| Score | 2.2759306 |
| Snippet | Inflammatory myofibroblastic tumors (IMT) are spindle cell proliferations with a characteristic fibro-inflammatory appearance, originally referred to as an... |
| SourceID | jstage |
| SourceType | Publisher |
| StartPage | 433 |
| SubjectTerms | 口底部 炎症性筋線維芽細胞腫 良性偽腫瘍 |
| Title | 口底部に発生した炎症性筋線維芽細胞腫の1例 |
| URI | https://www.jstage.jst.go.jp/article/jjoms/67/7/67_433/_article/-char/ja |
| Volume | 67 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | 日本口腔外科学会雑誌, 2021/07/20, Vol.67(7), pp.433-437 |
| journalDatabaseRights | – providerCode: PRVAFT databaseName: Open Access Digital Library customDbUrl: eissn: 2186-1579 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0001742264 issn: 0021-5163 databaseCode: KQ8 dateStart: 19670101 isFulltext: true titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html providerName: Colorado Alliance of Research Libraries |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrR1Na9RQMNR68SKKit_04DtJ1s3H-zp4eNnNUhQFoYXeQpJNDgu2RbcXT65FBAt6UYoe7MGDQql4EIWC_pm1ZsU_4cxksxuLh1q8PGbnzZs3byYvM5N9H5Z1JYaQPokV_unuQoIicmEr8NS2k8IjnXZTpTLcKHzrtphf9G8s8aWZI79qq5bW-kkjffDXfSWHsSrgwK64S_YfLDthCgiAwb5QgoWhPJCNWciZ6jDjIRAYpjkLNVMeM4qFHgSJzAQslExrrEXAZ7ozrtKyAjpYpVymQqIBGKoEroEwEjGmzRTxCaCW-AQCkaFiyrCgTRifBU3CeEyHBHDqvRQjdFgIFCEwqofD2A30ZzgBLWZatSERC5AYMAbkFiQKSOAQps2MIJ4tkkkzHVCVYsYwNfn2S2w6yAkZhzhYeKjwB3bXJg4G5JvSE0sYFzRE0fwJPSiIxDMwis6UHlShST_VCPbTByjqlB7Uq0nDHDUMMNFT43INcfURBp7qprTd5mTakAJIi8g-ICUJFnhkdxpHYK7-L5XW3RlIwp2xh8gIh3eM2Q4vb-ipXFx548l4Ksuav_I9rxb6-OX5O_u9KjDz0av2Vu7ebwjZmDT645zy8SyIiCwSMpJYAG1U1eA-wqgHycxRVwqB143cvFPLBbTfdGu5BVdSS2_yGwJl7VUHE9EHVEmbwMslXKUayo0tKO61urAQXPYg1aqWaVLkuHDCOj5O-eZMKd9Ja6YXn7Ku7z1_u7f78uf6--Fgu3i1W7zYGg42h4Ot4tGzYvPJj4fvip2N4svr4vPO6OnX4tPH0fqb0ePt4eCD8_3bxmlrsRMutObt8VUmdg9yfG7n4Bb9FF6KDo9Ft5m7qVR52uV5N_fjNHF1nmkIrDOR5Bn64CR3MPOPgbAreO55Z6zZ5ZXl7Kw1BxleArpKoBAQ5XANL1vh6DgHVJfr9JylytFGq-V5NdGBLXP-8E0vWMem8-KiNdu_t5ZdgnC9n1wmM_8GDdm5ZA |
| linkProvider | Colorado Alliance of Research Libraries |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E5%8F%A3%E5%BA%95%E9%83%A8%E3%81%AB%E7%99%BA%E7%94%9F%E3%81%97%E3%81%9F%E7%82%8E%E7%97%87%E6%80%A7%E7%AD%8B%E7%B7%9A%E7%B6%AD%E8%8A%BD%E7%B4%B0%E8%83%9E%E8%85%AB%E3%81%AE1%E4%BE%8B&rft.jtitle=%E6%97%A5%E6%9C%AC%E5%8F%A3%E8%85%94%E5%A4%96%E7%A7%91%E5%AD%A6%E4%BC%9A%E9%9B%91%E8%AA%8C&rft.au=%E8%8F%85%E5%8E%9F%2C+%E5%9C%AD%E4%BA%AE&rft.au=%E4%BC%8A%E8%97%A4%2C+%E5%92%8C%E5%AE%8F&rft.au=%E6%A9%8B%E6%9C%AC%2C+%E5%92%8C%E5%BD%A6&rft.au=%E7%89%87%E5%80%89%2C+%E6%9C%97&rft.date=2021-07-20&rft.pub=%E7%A4%BE%E5%9B%A3%E6%B3%95%E4%BA%BA+%E6%97%A5%E6%9C%AC%E5%8F%A3%E8%85%94%E5%A4%96%E7%A7%91%E5%AD%A6%E4%BC%9A&rft.issn=0021-5163&rft.eissn=2186-1579&rft.volume=67&rft.issue=7&rft.spage=433&rft.epage=437&rft_id=info:doi/10.5794%2Fjjoms.67.433&rft.externalDocID=article_jjoms_67_7_67_433_article_char_ja |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0021-5163&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0021-5163&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0021-5163&client=summon |