口蓋の小唾液腺に発生した基底細胞腺癌の1例

Basal cell adenocarcinoma (BCAC) is a rare tumor of the salivary gland and commonly arises in the parotid gland. It very rarely occurs in a minor salivary gland of the palate. We report the case of an 81-year-old Japanese woman with BCAC of the palatal minor salivary gland. Computed tomography and m...

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Published in日本口腔外科学会雑誌 Vol. 61; no. 7; pp. 363 - 367
Main Authors 新村, 兆一郎, 杉山, 昌彦, 西野, 辰太郎, 小間, 義朗, 藤本, 雄大, 上嶋, 伸知
Format Journal Article
LanguageJapanese
Published 社団法人 日本口腔外科学会 20.07.2015
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ISSN0021-5163
2186-1579
DOI10.5794/jjoms.61.363

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Abstract Basal cell adenocarcinoma (BCAC) is a rare tumor of the salivary gland and commonly arises in the parotid gland. It very rarely occurs in a minor salivary gland of the palate. We report the case of an 81-year-old Japanese woman with BCAC of the palatal minor salivary gland. Computed tomography and magnetic resonance imaging showed a mass (60 × 50 × 35mm) arising in the left side of the palate. The mass extended beyond the midline and invaded the maxillary sinus and pterygoid process. A biopsy was performed, and BCAC was diagnosed. Radiotherapy was administered at 2 Gy/fraction/day, and the total dose delivered to the primary tumor was 70 Gy. The lesion clinically shrank after radiotherapy. There has been no evidence of growth of the primary tumor or distant metastasis as of 24 months after radiotherapy.
AbstractList Basal cell adenocarcinoma (BCAC) is a rare tumor of the salivary gland and commonly arises in the parotid gland. It very rarely occurs in a minor salivary gland of the palate. We report the case of an 81-year-old Japanese woman with BCAC of the palatal minor salivary gland. Computed tomography and magnetic resonance imaging showed a mass (60 × 50 × 35mm) arising in the left side of the palate. The mass extended beyond the midline and invaded the maxillary sinus and pterygoid process. A biopsy was performed, and BCAC was diagnosed. Radiotherapy was administered at 2 Gy/fraction/day, and the total dose delivered to the primary tumor was 70 Gy. The lesion clinically shrank after radiotherapy. There has been no evidence of growth of the primary tumor or distant metastasis as of 24 months after radiotherapy.
Author 新村, 兆一郎
上嶋, 伸知
杉山, 昌彦
藤本, 雄大
小間, 義朗
西野, 辰太郎
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References 14) Akiyama K, Karaki M, et al: A massive basal cell adenocarcinoma of the palatal minor salivary gland that progressed into the pterygopalatine fossa. Int J Oral Maxillofac Surg 41: 444-447, 2012.
5) Lo AK, Topf JS, et al: Minor salivary gland basal cell adenocarcinoma of the palate. J Oral Maxillofac Surg 50: 531-534, 1992.
4) Toida M, Shimokawa K, et al: Intraoral minor salivary gland tumors: a clinicopathological study of 82 cases. Int J Oral Maxillofac Surg 34: 528-532, 2005.
10) Jayakrishnan A, Elmalah I, et al: Basal cell adenocarcinoma in minor salivary glands. Histopathology 42: 610-614, 2003.
6) Fonseca I and Soares J: Basal cell adenocarcinoma of minor salivary and seromucous glands of the head and neck region. Semin Diag Pathol 13: 128-137, 1996.
11) Parashar P, Baron E, et al: Basal cell adenocarcinoma of the oral minor salivary glands: review of the literature and presentation of two cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103: 77-84, 2007.
3) Buchner A, Merrell PW, et al: Relative frequency of intra-oral minor salivary gland tumors: a study of 380 cases from northern California and comparison to reports from other parts of the world. J Oral Pathol Med 36: 207-214, 2007.
1) Ellis GL and Wiscovitch JG: Basal cell adenocarcinomas of the major salivary glands. Oral Surg Oral Med Oral Pathol 69: 461-469, 1990.
19) Jingu K, Hasegawa A, et al: Carbon ion radiotherapy for basal cell adenocarcinoma of the head and neck: preliminary report of six cases and review of the literature. Radiat Oncol 5: 89, 2010.
17) Cheuk W and Chan JKC: Salivary gland tumors; Diagnostic Histopathology of tumors., second ed. Churchill Livingstone, London, 2000, p231-311.
9) 豊田博紀, 山口万枝, 他:口蓋に発生した基底細胞腺癌の1例.日口外誌 49: 99-102, 2003.
12) Yamagata K, Oka K, et al: Basal cell adenocarcinoma arising from the minor salivary gland in the soft palate: a case report. Pathol Res Pract 202: 475-480, 2006.
16) 小山芳徳, 麻生 晃, 他:耳下腺に発生した基底細胞腺癌の1例.日臨細胞会誌 39: 263-269, 2000.
15) Sarath PV, Kannan N, et al: Basal cell adenocarcinoma of the minor salivary glands involving palate and maxillary sinus. J Clin Imaging Sci 3: 4, 2013.
7) 川原明彦, 横山俊朗, 他:口蓋に発生したBasal cell adeno-carcinomaの1例. 日臨細胞九州会誌 30: 141-145, 1999.
18) 横地 恵, 栗田 浩, 他:痴呆を有する口腔癌患者の3例−管理上の問題点について−.口腔腫瘍 17: 131-136, 2005.
2) Nagao T, Sugao I, et al: Basal cell adenocarcinoma of the salivary glands comparison with basal cell adenoma through assessment of cell proliferation, apoptosis, and expression of p53 and bcl-2. Cancer 82: 439-447, 1998.
8) De Sousa SOM, Schwarzschild M, et al: Basal cell adenocarcinoma of the palate with squamous metaplasia. J Clin Pathol 53: 153-156, 2000.
13) Ward BK, Seethala RR, et al: Basal cell adenocarcinoma of a hard palate minor salivary gland: case report and review of the literature. Head Neck Oncol 1: 41, 2009.
References_xml – reference: 11) Parashar P, Baron E, et al: Basal cell adenocarcinoma of the oral minor salivary glands: review of the literature and presentation of two cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103: 77-84, 2007.
– reference: 13) Ward BK, Seethala RR, et al: Basal cell adenocarcinoma of a hard palate minor salivary gland: case report and review of the literature. Head Neck Oncol 1: 41, 2009.
– reference: 15) Sarath PV, Kannan N, et al: Basal cell adenocarcinoma of the minor salivary glands involving palate and maxillary sinus. J Clin Imaging Sci 3: 4, 2013.
– reference: 5) Lo AK, Topf JS, et al: Minor salivary gland basal cell adenocarcinoma of the palate. J Oral Maxillofac Surg 50: 531-534, 1992.
– reference: 6) Fonseca I and Soares J: Basal cell adenocarcinoma of minor salivary and seromucous glands of the head and neck region. Semin Diag Pathol 13: 128-137, 1996.
– reference: 18) 横地 恵, 栗田 浩, 他:痴呆を有する口腔癌患者の3例−管理上の問題点について−.口腔腫瘍 17: 131-136, 2005.
– reference: 16) 小山芳徳, 麻生 晃, 他:耳下腺に発生した基底細胞腺癌の1例.日臨細胞会誌 39: 263-269, 2000.
– reference: 4) Toida M, Shimokawa K, et al: Intraoral minor salivary gland tumors: a clinicopathological study of 82 cases. Int J Oral Maxillofac Surg 34: 528-532, 2005.
– reference: 7) 川原明彦, 横山俊朗, 他:口蓋に発生したBasal cell adeno-carcinomaの1例. 日臨細胞九州会誌 30: 141-145, 1999.
– reference: 17) Cheuk W and Chan JKC: Salivary gland tumors; Diagnostic Histopathology of tumors., second ed. Churchill Livingstone, London, 2000, p231-311.
– reference: 1) Ellis GL and Wiscovitch JG: Basal cell adenocarcinomas of the major salivary glands. Oral Surg Oral Med Oral Pathol 69: 461-469, 1990.
– reference: 14) Akiyama K, Karaki M, et al: A massive basal cell adenocarcinoma of the palatal minor salivary gland that progressed into the pterygopalatine fossa. Int J Oral Maxillofac Surg 41: 444-447, 2012.
– reference: 9) 豊田博紀, 山口万枝, 他:口蓋に発生した基底細胞腺癌の1例.日口外誌 49: 99-102, 2003.
– reference: 2) Nagao T, Sugao I, et al: Basal cell adenocarcinoma of the salivary glands comparison with basal cell adenoma through assessment of cell proliferation, apoptosis, and expression of p53 and bcl-2. Cancer 82: 439-447, 1998.
– reference: 12) Yamagata K, Oka K, et al: Basal cell adenocarcinoma arising from the minor salivary gland in the soft palate: a case report. Pathol Res Pract 202: 475-480, 2006.
– reference: 10) Jayakrishnan A, Elmalah I, et al: Basal cell adenocarcinoma in minor salivary glands. Histopathology 42: 610-614, 2003.
– reference: 19) Jingu K, Hasegawa A, et al: Carbon ion radiotherapy for basal cell adenocarcinoma of the head and neck: preliminary report of six cases and review of the literature. Radiat Oncol 5: 89, 2010.
– reference: 8) De Sousa SOM, Schwarzschild M, et al: Basal cell adenocarcinoma of the palate with squamous metaplasia. J Clin Pathol 53: 153-156, 2000.
– reference: 3) Buchner A, Merrell PW, et al: Relative frequency of intra-oral minor salivary gland tumors: a study of 380 cases from northern California and comparison to reports from other parts of the world. J Oral Pathol Med 36: 207-214, 2007.
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基底細胞腺癌
小唾液腺
Title 口蓋の小唾液腺に発生した基底細胞腺癌の1例
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