上顎前歯部顎骨内に発生した孤立性神経線維腫の1例
The 2017 WHO classification of Head and Neck Tumors defines solitary intraosseous neurofibroma of the maxilla (SINM) as an admixture of Schwann cells, fibroblasts, perineurial cells, and axons. Abundant soft tissue is observed in the oral and maxillofacial region, and occurrence in the mandible, and...
Saved in:
| Published in | 日本口腔外科学会雑誌 Vol. 64; no. 3; pp. 189 - 194 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
社団法人 日本口腔外科学会
20.03.2018
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0021-5163 2186-1579 |
| DOI | 10.5794/jjoms.64.189 |
Cover
| Abstract | The 2017 WHO classification of Head and Neck Tumors defines solitary intraosseous neurofibroma of the maxilla (SINM) as an admixture of Schwann cells, fibroblasts, perineurial cells, and axons. Abundant soft tissue is observed in the oral and maxillofacial region, and occurrence in the mandible, and especially in the maxilla, is extremely rare. We report a case of SINM occurring in the anterior tooth region of the maxilla. The patient was a 50-year-old woman who had discomfort in the anterior teeth of the left side of the maxilla and was referred to this department by her personal physician. A biopsy was performed, and a neurogenic tumor was suspected. Maxillary tumor resection and bone transplantation were performed with the patient under general anesthesia. The histopathological examination showed strong positivity for vimentin and positivity for S100 and NSE, and neurofibroma was diagnosed. Two years 7 months have passed since surgery, and there has been no sign of recurrence. |
|---|---|
| AbstractList | The 2017 WHO classification of Head and Neck Tumors defines solitary intraosseous neurofibroma of the maxilla (SINM) as an admixture of Schwann cells, fibroblasts, perineurial cells, and axons. Abundant soft tissue is observed in the oral and maxillofacial region, and occurrence in the mandible, and especially in the maxilla, is extremely rare. We report a case of SINM occurring in the anterior tooth region of the maxilla. The patient was a 50-year-old woman who had discomfort in the anterior teeth of the left side of the maxilla and was referred to this department by her personal physician. A biopsy was performed, and a neurogenic tumor was suspected. Maxillary tumor resection and bone transplantation were performed with the patient under general anesthesia. The histopathological examination showed strong positivity for vimentin and positivity for S100 and NSE, and neurofibroma was diagnosed. Two years 7 months have passed since surgery, and there has been no sign of recurrence. |
| Author | 渡邉, 美貴 橋本, 和彦 片倉, 朗 山本, 雅絵 薬師寺, 孝 柴原, 孝彦 |
| Author_xml | – sequence: 1 fullname: 渡邉, 美貴 organization: 東京歯科大学口腔顎顔面外科学講座 – sequence: 1 fullname: 薬師寺, 孝 organization: 独立行政法人国立病院機構高崎総合医療センター – sequence: 1 fullname: 片倉, 朗 organization: 東京歯科大学口腔病態外科学講座 – sequence: 1 fullname: 柴原, 孝彦 organization: 東京歯科大学口腔顎顔面外科学講座 – sequence: 1 fullname: 山本, 雅絵 organization: 東京歯科大学口腔病態外科学講座 – sequence: 1 fullname: 橋本, 和彦 organization: 東京歯科大学臨床検査病理学講座 |
| BookMark | eNo9kEtLw0AAhBepYK29-TcS95ndnESKVaHgRc9hu0m0oQ9JevFmkAra6kkQPVgExWKonnzgwT-Ttmv_hfGBl5mBb5jDzINcs9X0AFhE0GTcpktB0GpEpkVNJOwZkMdIWAbKSA7kIcTIYMgic6AYRbUqhExwmxMrD8qjt5Ppzdn4-HQyfJoeDrI8fRiMjzppnOjLd33eT-OLNO6Ph7c66U4O7vXdtX7u6dcr_TL87CRp_IhGH90FMOvLeuQV_7wAtsurW6V1o7K5tlFaqRgBJhAaXDLfpphWqcASSsyoT6TNMKKCuB7JKghJT_iKKMpd7FsK2cKlXBHoM0Y5KYDl390gassdz9kLaw0Z7jsybNdU3XN-TnAs6pBvyZ74J2pXhk4gyRditHFu |
| ContentType | Journal Article |
| Copyright | 2018 社団法人 日本口腔外科学会 |
| Copyright_xml | – notice: 2018 社団法人 日本口腔外科学会 |
| DOI | 10.5794/jjoms.64.189 |
| DatabaseTitleList | |
| DeliveryMethod | fulltext_linktorsrc |
| EISSN | 2186-1579 |
| EndPage | 194 |
| ExternalDocumentID | article_jjoms_64_3_64_189_article_char_ja |
| GroupedDBID | ALMA_UNASSIGNED_HOLDINGS F5P JSF KQ8 RJT |
| ID | FETCH-LOGICAL-j2300-7a5f9424b482a0a254f3a9521483de330011ae8fc3c47d2f6c198d47c30f55473 |
| ISSN | 0021-5163 |
| IngestDate | Wed Sep 03 06:30:06 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | true |
| Issue | 3 |
| Language | Japanese |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-j2300-7a5f9424b482a0a254f3a9521483de330011ae8fc3c47d2f6c198d47c30f55473 |
| OpenAccessLink | https://www.jstage.jst.go.jp/article/jjoms/64/3/64_189/_article/-char/ja |
| PageCount | 6 |
| ParticipantIDs | jstage_primary_article_jjoms_64_3_64_189_article_char_ja |
| PublicationCentury | 2000 |
| PublicationDate | 2018/03/20 |
| PublicationDateYYYYMMDD | 2018-03-20 |
| PublicationDate_xml | – month: 03 year: 2018 text: 2018/03/20 day: 20 |
| PublicationDecade | 2010 |
| PublicationTitle | 日本口腔外科学会雑誌 |
| PublicationTitleAlternate | 日口外誌 |
| PublicationYear | 2018 |
| Publisher | 社団法人 日本口腔外科学会 |
| Publisher_xml | – name: 社団法人 日本口腔外科学会 |
| References | 8) 山田和祐， 亀井達哉， 他：舌に発生した孤立性神経線維腫の１例．日口外誌 30: 1549-1552, 1984. 13) 秋山明美， 八若保孝， 他：上顎前歯部歯槽堤に発生した先天性神経線維腫の1例．小児歯誌 36: 144-153, 1998. 14) 兒玉正明， 土生 学， 他：下顎骨内に発生した孤立性神経線維腫の1例．九州歯会誌 59: 215-220, 2005. 2) Mori H, Kakuta S, et al : Solitary intraosseous neurofibroma of the maxilla: report of a case. J Oral Maxillofac Surg 51: 688-690, 1993. 10) 柳沢繁孝， 大竹弘司， 他：口唇部に発生した神経原性腫瘍の5例．日口外誌 31: 325-330, 1985. 4) Sharma P, Narwal A, et al : Intraosseous neurofibroma of maxilla in a child. J Indian Soc Pedod Prev Dent 27: 62-64, 2009. 15) Ohno J, Iwahashi T, et al : Solitary neurofibroma of the gingiva with prominent differentiation of Meissner bodies: a case report. Diagn Pathol 5: 61 2010.Available at: http://www.diagnosticpathology.org/ content/5/1/61 Accessed November 5, 2014. 18) Rokutanda S, Yamada S, et al : Solitary neurofibroma of the maxillary sinus: Report of a case. J Oral Maxillofac Surg Med Pathol 24: 171-174, 2012. 22) Charalabos A, Dimitris A, et al : Solitary intraosseous neurofibroma of the inferior alveolar nerve: report of a case. J Oral Maxillofac Surg 59: 232-235, 2001. 3) Richard JP and Sheldon M : Solitary intrabony neurofibroma of the Maxilla. J Oral Maxillofac Surg 55: 768-772, 1997. 7) 山田和祐， 藤田 靖， 他：下顎骨に発生した神経線維腫の1例．日口外誌 29: 553-556, 1983. 12) 岩田一成， 嶋田 淳， 他：1 歳1 か月の女児に発症した孤立性神経線維腫の1例．日口外誌 40: 314-316, 1994. 21) Chris AS and George CS : Solitary neurofibroma of the maxilla: report of a case. J Oral Maxillofac Surg 46: 701-705, 1988. 6) Zachariades N, Mezitis M, et al : Benign neurogenic tumors of the oral cavity. Int J Oral Maxillofac Surg 16: 70-76, 1987. 24) Hirokawa Y, Nheu T, et al : Sichuan pepper extracts block the PAK1 Cyclin D1 pathway and the growth of NF1 deficient cancer xenograft in mice. Cancer Biology & Therapy 5: 305-309, 2006. 1) Adel K, John KC, et al : World health organization classification of head and neck tumors. IARC Press, Lyon, 2017, p123-124. 20) Brady GL, Schaffner DL, et al : Solitary neurofibroma of the maxilla. J Oral Maxillofac Surg 40: 453-456, 1982. 16) Tanaka S, Okada H, et al : A Case of a Huge Solitary Neurofibroma Extending from the Tongue to the Floor of the Mouth. Int J Oral-Med Sci 8: 171-174, 2010 5) 谷口真一， 石原茂人， 他：上顎骨に発生した孤立性神経線維腫の1例．日口外誌 59: 331-335, 2013. 23) Nicholas Z, Michariades M, et al : Benign neurogenic tumors of the oral cavity. Int J Oral Maxillofac Surg 16: 70-76, 1987. 9) 北村幸郷， 横山道明， 他：上顎洞に発生し Neurofibroma の1例．耳鼻臨床 78: 1847-1851, 1985. 11) 楠川仁悟， 田中俊一， 他：口蓋に発生した孤立性神経線維腫の1例．日口外誌 35: 774-777, 1989. 17) 植田祐子， 中野旬之， 他：下顎骨内に発生した孤立性神経線維腫の1例．口腔腫瘍 23: 27-31, 2011. 19) Be`la BT, William HL, et al : Central pacinian neurofibroma of the maxilla. Oral Surg Oral Med Oral Pathol 39: 630-634, 1975. |
| References_xml | – reference: 10) 柳沢繁孝， 大竹弘司， 他：口唇部に発生した神経原性腫瘍の5例．日口外誌 31: 325-330, 1985. – reference: 19) Be`la BT, William HL, et al : Central pacinian neurofibroma of the maxilla. Oral Surg Oral Med Oral Pathol 39: 630-634, 1975. – reference: 15) Ohno J, Iwahashi T, et al : Solitary neurofibroma of the gingiva with prominent differentiation of Meissner bodies: a case report. Diagn Pathol 5: 61 2010.Available at: http://www.diagnosticpathology.org/ content/5/1/61 Accessed November 5, 2014. – reference: 22) Charalabos A, Dimitris A, et al : Solitary intraosseous neurofibroma of the inferior alveolar nerve: report of a case. J Oral Maxillofac Surg 59: 232-235, 2001. – reference: 13) 秋山明美， 八若保孝， 他：上顎前歯部歯槽堤に発生した先天性神経線維腫の1例．小児歯誌 36: 144-153, 1998. – reference: 24) Hirokawa Y, Nheu T, et al : Sichuan pepper extracts block the PAK1 Cyclin D1 pathway and the growth of NF1 deficient cancer xenograft in mice. Cancer Biology & Therapy 5: 305-309, 2006. – reference: 9) 北村幸郷， 横山道明， 他：上顎洞に発生し Neurofibroma の1例．耳鼻臨床 78: 1847-1851, 1985. – reference: 23) Nicholas Z, Michariades M, et al : Benign neurogenic tumors of the oral cavity. Int J Oral Maxillofac Surg 16: 70-76, 1987. – reference: 4) Sharma P, Narwal A, et al : Intraosseous neurofibroma of maxilla in a child. J Indian Soc Pedod Prev Dent 27: 62-64, 2009. – reference: 12) 岩田一成， 嶋田 淳， 他：1 歳1 か月の女児に発症した孤立性神経線維腫の1例．日口外誌 40: 314-316, 1994. – reference: 16) Tanaka S, Okada H, et al : A Case of a Huge Solitary Neurofibroma Extending from the Tongue to the Floor of the Mouth. Int J Oral-Med Sci 8: 171-174, 2010 – reference: 1) Adel K, John KC, et al : World health organization classification of head and neck tumors. IARC Press, Lyon, 2017, p123-124. – reference: 8) 山田和祐， 亀井達哉， 他：舌に発生した孤立性神経線維腫の１例．日口外誌 30: 1549-1552, 1984. – reference: 7) 山田和祐， 藤田 靖， 他：下顎骨に発生した神経線維腫の1例．日口外誌 29: 553-556, 1983. – reference: 5) 谷口真一， 石原茂人， 他：上顎骨に発生した孤立性神経線維腫の1例．日口外誌 59: 331-335, 2013. – reference: 20) Brady GL, Schaffner DL, et al : Solitary neurofibroma of the maxilla. J Oral Maxillofac Surg 40: 453-456, 1982. – reference: 17) 植田祐子， 中野旬之， 他：下顎骨内に発生した孤立性神経線維腫の1例．口腔腫瘍 23: 27-31, 2011. – reference: 6) Zachariades N, Mezitis M, et al : Benign neurogenic tumors of the oral cavity. Int J Oral Maxillofac Surg 16: 70-76, 1987. – reference: 11) 楠川仁悟， 田中俊一， 他：口蓋に発生した孤立性神経線維腫の1例．日口外誌 35: 774-777, 1989. – reference: 14) 兒玉正明， 土生 学， 他：下顎骨内に発生した孤立性神経線維腫の1例．九州歯会誌 59: 215-220, 2005. – reference: 2) Mori H, Kakuta S, et al : Solitary intraosseous neurofibroma of the maxilla: report of a case. J Oral Maxillofac Surg 51: 688-690, 1993. – reference: 21) Chris AS and George CS : Solitary neurofibroma of the maxilla: report of a case. J Oral Maxillofac Surg 46: 701-705, 1988. – reference: 18) Rokutanda S, Yamada S, et al : Solitary neurofibroma of the maxillary sinus: Report of a case. J Oral Maxillofac Surg Med Pathol 24: 171-174, 2012. – reference: 3) Richard JP and Sheldon M : Solitary intrabony neurofibroma of the Maxilla. J Oral Maxillofac Surg 55: 768-772, 1997. |
| SSID | ssib005879736 ssib058493840 ssj0001742264 ssib000940266 |
| Score | 2.1387174 |
| Snippet | The 2017 WHO classification of Head and Neck Tumors defines solitary intraosseous neurofibroma of the maxilla (SINM) as an admixture of Schwann cells,... |
| SourceID | jstage |
| SourceType | Publisher |
| StartPage | 189 |
| SubjectTerms | 上顎骨 孤立性 神経線維腫 骨内 |
| Title | 上顎前歯部顎骨内に発生した孤立性神経線維腫の1例 |
| URI | https://www.jstage.jst.go.jp/article/jjoms/64/3/64_189/_article/-char/ja |
| Volume | 64 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | 日本口腔外科学会雑誌, 2018/03/20, Vol.64(3), pp.189-194 |
| journalDatabaseRights | – providerCode: PRVAFT databaseName: Open Access Digital Library customDbUrl: eissn: 2186-1579 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0001742264 issn: 0021-5163 databaseCode: KQ8 dateStart: 19670101 isFulltext: true titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html providerName: Colorado Alliance of Research Libraries |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrR1Na9VAMJTqwYsoKn7Tg3uS1CT7kd1j8ppQFAWhhd5CkpccHtiKvl48-ZAKWvUkiB4sgmKxVE9-4ME_89rG_gtnJnmvUTzUIpQwb3d2PrvMTMjuWNalAmIwBM6urY2AAsVoZaeFgY0nZTeD8CnzHAvF6zfU7Ly4uiAXJiYPt75aWu5n0_m9v54rOYhXYQz8iqdk_8GzY6IwADD4F57gYXjuy8csEizUTAcsMixwmY5YJJk2TM-wSLFghgUxTmnOAt3CASCgEUBWTEsWccgoWRCyyGfGsDAgQDATN1PGHwExrkLKAnFgiQ6Rl3ZY4NOIZCZCIATiHQKAFBEMSaRII0fkVTONXFIjAkLtTBmJGiKHQIcFHRI3ZgFvSIB8KApIqYgxsHFHwimi2SHGhpmQpjSqrcevhZEwWA9sgiby0G7w_0aCRmQmzUKPhWIPXyOrWhBcGBK3GM1FC4m1mdnD98kXPgnujOmTOsZviwFWDUkbYAtwmxoxQ43a72dcOrDoOeMdRQYgKwI6qItGAu04M5IsEcDf5f9l0nak81xbuk3wKGgM24_Zrqyb94yiX32HfLPLeSuUuXVrpyYrcutW1H8GXCAmMOD2lm7dnVZierzotyvMmw2SEFqiRMLxAbjJaAaPGCY9qHMOeb5S2Ink2s1WmWCE47XKDql94_Pxb8ihDR_dWUTvVn06H15_3VWboT7zguJeaQsLeWcPqrDRF5yUVM4ds4421eBUUMt33JropSeseOvb4903z7YfPd3Z_LT7YB3g3Q_r2w9XhoON6uX36vnacPBiOFjb3nxbbazu3H9fvXtdfX5SfX1Vfdn8ubIxHHx0t36snrTm42iuM2s37U7snscdx_ZTWRrhiUxoL3VST4qSpwbSa6F5t-Acq7e00GXOc-F3vVLlrtFd4efcKSW2ED9lTS4uLRanrakUywaVeV5apEKVItNcaeM4WSZTt8zLM5au1U5u13faJPt20dmDLz1nHdnbIOetyf6d5eICpPT97CL5-xf0IsMU |
| linkProvider | Colorado Alliance of Research Libraries |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E4%B8%8A%E9%A1%8E%E5%89%8D%E6%AD%AF%E9%83%A8%E9%A1%8E%E9%AA%A8%E5%86%85%E3%81%AB%E7%99%BA%E7%94%9F%E3%81%97%E3%81%9F%E5%AD%A4%E7%AB%8B%E6%80%A7%E7%A5%9E%E7%B5%8C%E7%B7%9A%E7%B6%AD%E8%85%AB%E3%81%AE1%E4%BE%8B&rft.jtitle=%E6%97%A5%E6%9C%AC%E5%8F%A3%E8%85%94%E5%A4%96%E7%A7%91%E5%AD%A6%E4%BC%9A%E9%9B%91%E8%AA%8C&rft.au=%E6%B8%A1%E9%82%89%2C+%E7%BE%8E%E8%B2%B4&rft.au=%E8%96%AC%E5%B8%AB%E5%AF%BA%2C+%E5%AD%9D&rft.au=%E7%89%87%E5%80%89%2C+%E6%9C%97&rft.au=%E6%9F%B4%E5%8E%9F%2C+%E5%AD%9D%E5%BD%A6&rft.date=2018-03-20&rft.pub=%E7%A4%BE%E5%9B%A3%E6%B3%95%E4%BA%BA+%E6%97%A5%E6%9C%AC%E5%8F%A3%E8%85%94%E5%A4%96%E7%A7%91%E5%AD%A6%E4%BC%9A&rft.issn=0021-5163&rft.eissn=2186-1579&rft.volume=64&rft.issue=3&rft.spage=189&rft.epage=194&rft_id=info:doi/10.5794%2Fjjoms.64.189&rft.externalDocID=article_jjoms_64_3_64_189_article_char_ja |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0021-5163&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0021-5163&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0021-5163&client=summon |