小児の下顎歯肉に生じた筋線維腫の１例
Myofibroma, first reported by Stout in 1954, is a solitary tumor primarily found in the skin, bones, and gastrointestinal tract of infants. Its occurrence is as rare as two to four cases per one million people and, so far, only 19 cases have been reported in Japan. We report a case of myofibroma in...
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| Published in | 日本口腔外科学会雑誌 Vol. 71; no. 7; pp. 323 - 330 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | Japanese |
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公益社団法人 日本口腔外科学会
20.07.2025
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| Online Access | Get full text |
| ISSN | 0021-5163 2186-1579 |
| DOI | 10.5794/jjoms.71.323 |
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| Abstract | Myofibroma, first reported by Stout in 1954, is a solitary tumor primarily found in the skin, bones, and gastrointestinal tract of infants. Its occurrence is as rare as two to four cases per one million people and, so far, only 19 cases have been reported in Japan. We report a case of myofibroma in the left mandibular molar gingiva of a 7-year-old boy. He noticed swelling in the left lower mandibular molar region one month before his first visit to our department, after which he consulted the referring hospital. A biopsy was performed at the referring hospital, and he was diagnosed with a benign mesenchymal tumor and referred to our department. At the initial consultation, we observed an elastic hard mass measuring 30 × 21 mm with normal surface mucosa. The tumor was resected under general anesthesia, and a histopathological examination of the resected specimen led to a diagnosis of myofibroma. There is no evidence of recurrence six years after surgery. |
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| AbstractList | Myofibroma, first reported by Stout in 1954, is a solitary tumor primarily found in the skin, bones, and gastrointestinal tract of infants. Its occurrence is as rare as two to four cases per one million people and, so far, only 19 cases have been reported in Japan. We report a case of myofibroma in the left mandibular molar gingiva of a 7-year-old boy. He noticed swelling in the left lower mandibular molar region one month before his first visit to our department, after which he consulted the referring hospital. A biopsy was performed at the referring hospital, and he was diagnosed with a benign mesenchymal tumor and referred to our department. At the initial consultation, we observed an elastic hard mass measuring 30 × 21 mm with normal surface mucosa. The tumor was resected under general anesthesia, and a histopathological examination of the resected specimen led to a diagnosis of myofibroma. There is no evidence of recurrence six years after surgery. |
| Author | 柳生 貴裕 河上 真緒 大澤 政裕 舟山 直希 中村 泰士 山川 延宏 |
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| Copyright | 2025 社団法人 日本口腔外科学会 |
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| References_xml | – reference: 8) 石井正俊，石井良昌，他：下顎骨に発生した筋線維腫症の１例．日口外誌 44: 768-770, 1998. – reference: 36) Kim JS, Kim SE, et al : Myofibroma of the mandible: A case report. Imaging Sci Dent 36: 211-215, 2006. – reference: 56) Lopes RN, Alves FA, et al : Head and neck solitary infantile myofibroma: Clinicopathological and immunohistochemical features of a case series. Acta Histochem 117: 431-436, 2015. – reference: 74) Vered M, Allon I, et al : Clinico-pathologic correlations of myofibroblastic tumors of the oral cavity. Ⅱ. Myofibroma and myofibromatosis of the oral soft tissues. J Oral Pathol Med 36: 304-314, 2007. – reference: 7) 乾真登可，田川俊郎，他：下顎骨に発生した筋線維腫症の１例．日口外誌 43: 628-630, 1997. – reference: 41) Ramadorai A, Rajsekaran A, et al : A Case Report of Solitary, Intraosseous, Adult-Onset Myofibroma of the Mandible. J Maxillofac Oral Surg 9: 280-283, 2010. – reference: 3) Chung EB and Enzinger FM : Infantile myofibromatosis. Cancer 48: 1807-1818, 1981. – reference: 65) Mesquita CM, Silva CW, et al : Myofibroma in pediatric patients: Diagnosis and treatment of a rare lesion. Oral Surg Oral Med Oral Pathol Oral Radiol 129: e97, 2020. Available from : Science Direct. Accessed December 10, 2024. – reference: 45) Nouri H, Aderdour L, et al : Myofibroma of the mandibule: a case report. Rev Laryngol Otol Rhinol 132: 115-117, 2011. – reference: 6) Sugatani T, Inui M, et al : Myofibroma of the mandible. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 80: 303-309, 1995. – reference: 30) Jones AC, Freedman PD, et al : Oral myofibromas: A report of 13 cases and review of the literature. J Oral Maxillofac Surg 52: 870-875, 1994. – reference: 16) 中山竜司，星健太郎，他：舌に発生した筋線維腫様病変の１例．日口外誌 55: 22-24, 2009. – reference: 18) 村松恭太郎，大金 覚，他：成人の下顎骨に発生した筋線維腫の１例．日口外誌 59: 643-647, 2013. – reference: 57) Castro HHO, Gomes HE, et al : Myofibroma of the mandible-Case report. Pediatr Dent J 26: 38-41, 2016. – reference: 4) Enzinger FM and Weiss SW : Soft tissue tumors, 3rd Ed. Mosby, St Louis, 1995, p238-245. – reference: 38) Chtourou I, Makni SK, et al : Pediatric mandibular myofibromatosis. Rev Stomatol Chir Maxillofac 108: 461-464, 2007. – reference: 79) Duffy MT, Harris M, et al : Infantile myofibromatosis of orbital bone. A case report with computed tomography, magnetic resonance imaging, and histologic findings. Ophthalmology 104: 1471-1474, 1997. – reference: 66) Savithri V, Suresh R, et al : Oral myofibroma presenting as an aggressive gingival lesion. BMJ Case Rep 14: e242700, 2021. Available from : National Library of Medicine. Accessed December 10, 2024. – reference: 63) Strub M, Blein E, et al : Diagnosis and Therapeutic Care of Infantile Myofibroma Of the Jaws: A CaseReport and Literature Systematic Review. Dent Oral Biol Craniofac Res 2019. Available from : Science Repository. 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| Title | 小児の下顎歯肉に生じた筋線維腫の１例 |
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