舌下腺に発生し診断に苦慮したオンコサイトーマの１例
We report a case of oncocytoma arising in the sublingual gland. The patient was a 53-year-old woman referred to our department because of a swelling in the left oral floor. Magnetic resonance imaging revealed a mass with clear borders measuring approximately 25 × 20 mm in the left sublingual space,...
Saved in:
| Published in | 日本口腔外科学会雑誌 Vol. 71; no. 7; pp. 336 - 340 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
公益社団法人 日本口腔外科学会
20.07.2025
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0021-5163 2186-1579 |
| DOI | 10.5794/jjoms.71.336 |
Cover
| Abstract | We report a case of oncocytoma arising in the sublingual gland. The patient was a 53-year-old woman referred to our department because of a swelling in the left oral floor. Magnetic resonance imaging revealed a mass with clear borders measuring approximately 25 × 20 mm in the left sublingual space, showing heterogeneous enhancement with contrast. The initial pathological diagnosis from a tissue biopsy was mucoepidermoid carcinoma. The patient underwent a tumor resection under general anesthesia. Pathological examinations showed that tumor cells consisted of proliferation of eosinophilic cells with granular cytoplasm, and immunohistochemistry revealed that the tumor cells showed a diffuse positive reaction for mitochondria. Based on these findings, the lesion was finally diagnosed as oncocytoma. No sign of recurrence has been observed one year and two months after surgery. |
|---|---|
| AbstractList | We report a case of oncocytoma arising in the sublingual gland. The patient was a 53-year-old woman referred to our department because of a swelling in the left oral floor. Magnetic resonance imaging revealed a mass with clear borders measuring approximately 25 × 20 mm in the left sublingual space, showing heterogeneous enhancement with contrast. The initial pathological diagnosis from a tissue biopsy was mucoepidermoid carcinoma. The patient underwent a tumor resection under general anesthesia. Pathological examinations showed that tumor cells consisted of proliferation of eosinophilic cells with granular cytoplasm, and immunohistochemistry revealed that the tumor cells showed a diffuse positive reaction for mitochondria. Based on these findings, the lesion was finally diagnosed as oncocytoma. No sign of recurrence has been observed one year and two months after surgery. |
| Author | 山田 朋弘 鳴瀬 智史 片瀬 直樹 竹村 彩夏 森下 廣太 福嶋 大将 |
| Author_xml | – sequence: 1 fullname: 竹村 彩夏 organization: 長崎大学大学院医歯薬学総合研究科医療科学専攻口腔顎顔面外科学分野 – sequence: 1 fullname: 福嶋 大将 organization: 長崎大学大学院医歯薬学総合研究科医療科学専攻口腔顎顔面外科学分野 – sequence: 1 fullname: 森下 廣太 organization: 長崎大学大学院医歯薬学総合研究科医療科学専攻口腔顎顔面外科学分野 – sequence: 1 fullname: 鳴瀬 智史 organization: 長崎大学大学院医歯薬学総合研究科医療科学専攻口腔顎顔面外科学分野 – sequence: 1 fullname: 片瀬 直樹 organization: 長崎大学大学院医歯薬学総合研究科医療科学専攻口腔病理学分野 – sequence: 1 fullname: 山田 朋弘 organization: 長崎大学大学院医歯薬学総合研究科医療科学専攻口腔顎顔面外科学分野 |
| BookMark | eNo9kEtLw0AcxBepYKy9-TVS97_bfeQkUnxhwYuewzbZaEMfkvTiMQ2FQr0IonixFxFR7EUEKcUvs6XNza9gfCAMM_AbmMOsokK709YIrQMuM-FUNsKw04rLAsqU8iVkEZDchrwpIAtjAjYDTldQKY4bdYyZFI6g3EIH2eBi9j7M-hOTPC9uJ4urkUlussfJ_PolJ9nwYd4f58QkI9N7Mumr6eV6M717kw5MOjXpnUnGn9PL2cdwDS0Hqhnr0l8W0fHO9lF1z64d7u5Xt2p2SDAHW_nSI1IqH4NyHOJRxrRk9QqThPpUEaaBVAQOpCeBKg7cB-zROtdCUj_APi2izd_dMO6qE-2eRY2Wis5dFXUbXlO7P0-4Alzxbfkd_413qiI3VPQLAM11JQ |
| ContentType | Journal Article |
| Copyright | 2025 社団法人 日本口腔外科学会 |
| Copyright_xml | – notice: 2025 社団法人 日本口腔外科学会 |
| DOI | 10.5794/jjoms.71.336 |
| DatabaseTitleList | |
| DeliveryMethod | fulltext_linktorsrc |
| EISSN | 2186-1579 |
| EndPage | 340 |
| ExternalDocumentID | article_jjoms_71_7_71_336_article_char_ja |
| GroupedDBID | ALMA_UNASSIGNED_HOLDINGS F5P JSF KQ8 RJT |
| ID | FETCH-LOGICAL-j2061-ad8c288ad01a992c355e85b45823d3a25e12470f8c813a616d10c3b6e783df0d3 |
| ISSN | 0021-5163 |
| IngestDate | Mon Sep 01 00:08:31 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | true |
| Issue | 7 |
| Language | Japanese |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-j2061-ad8c288ad01a992c355e85b45823d3a25e12470f8c813a616d10c3b6e783df0d3 |
| OpenAccessLink | https://www.jstage.jst.go.jp/article/jjoms/71/7/71_336/_article/-char/ja |
| PageCount | 5 |
| ParticipantIDs | jstage_primary_article_jjoms_71_7_71_336_article_char_ja |
| PublicationCentury | 2000 |
| PublicationDate | 2025/07/20 |
| PublicationDateYYYYMMDD | 2025-07-20 |
| PublicationDate_xml | – month: 07 year: 2025 text: 2025/07/20 day: 20 |
| PublicationDecade | 2020 |
| PublicationTitle | 日本口腔外科学会雑誌 |
| PublicationTitleAlternate | 日口外誌 |
| PublicationYear | 2025 |
| Publisher | 公益社団法人 日本口腔外科学会 |
| Publisher_xml | – name: 公益社団法人 日本口腔外科学会 |
| References | 13) Sepulveda I, Platin E, et al : Oncocytoma of the parotid gland: a case report and review of the literature. Case Rep Oncol 7: 109-116, 2014. 7) Lin Y, Wang Y, et al : Sublingual Gland Tumors Worldwide: A Descriptive Retrospective Study of 839 Cases. J Oral Maxillofac Surg 78: 1546-1556, 2020. 11) 鬼頭良輔，海沼和幸，他：唾液腺癌の組織学的悪性度診断と予後予測におけるFDG-PETの有用性の検討．頭頸部癌 37: 73-77, 2011. 14) 宮城佳美，三木絵里，他：Oncocyticな唾液腺腫瘍の２例．診断病理 38: 151-156, 2021. 4) 新宮崇之，吉田 優，他：頰部に発生したoncocytomaの１例．日口外誌 68: 254-258, 2022. 6) Sun G, Yang X, et al : The treatment of sublingual gland tumours. Int J Oral Maxillofac Surg 39: 863-868, 2010. 10) Sato N, Nakamura Y, et al : Case report: adrenal oncocytoma associated with markedly increased FDG uptake and immunohistochemically positive for GLUT1. Endocr Pathol 25: 410-415, 2014. 8) Kato H, Fujimoto K, et al : Usefulness of diffusionweighted MR imaging for differentiating between Warthin's tumor and oncocytoma of the parotid gland. Jpn J Radiol 35: 78-85, 2017. 2) Zhou CX and Gao Y : Oncocytoma of the salivary glands: a clinicopathologic and immunohistochemical study. Oral Oncol 45: 232-238, 2009. 9) Matsusue E, Fujihara Y, et al : Vanishing Parotid Tumors on MR imaging. Yonago Acta Med 61: 033-039, 2018. 1) Neville BW, Damm DD, et al : Oral and Maxillofacial Pathology, 3rd edn. Saunders, Elsevier, 2009, p683-684. 3) 林 祐太郎，小川主税，他： 顎下腺に発生したoncocytomaの１例．日口外誌 70: 128-133, 2024. 5) Katabi N and Assaad A : Oncocytoma. In EL-Naggar AK, Chan JKC, eds ; WHO classification of Head and Neck Tumours. IARC Press, Lyon, 2017, p189-190. 12) 川村和弘，西田陽登，他：オコサイト化生主体の粘表皮癌の１例．診断病理 40: 179-185, 2023. |
| References_xml | – reference: 13) Sepulveda I, Platin E, et al : Oncocytoma of the parotid gland: a case report and review of the literature. Case Rep Oncol 7: 109-116, 2014. – reference: 3) 林 祐太郎，小川主税，他： 顎下腺に発生したoncocytomaの１例．日口外誌 70: 128-133, 2024. – reference: 4) 新宮崇之，吉田 優，他：頰部に発生したoncocytomaの１例．日口外誌 68: 254-258, 2022. – reference: 9) Matsusue E, Fujihara Y, et al : Vanishing Parotid Tumors on MR imaging. Yonago Acta Med 61: 033-039, 2018. – reference: 14) 宮城佳美，三木絵里，他：Oncocyticな唾液腺腫瘍の２例．診断病理 38: 151-156, 2021. – reference: 1) Neville BW, Damm DD, et al : Oral and Maxillofacial Pathology, 3rd edn. Saunders, Elsevier, 2009, p683-684. – reference: 12) 川村和弘，西田陽登，他：オコサイト化生主体の粘表皮癌の１例．診断病理 40: 179-185, 2023. – reference: 5) Katabi N and Assaad A : Oncocytoma. In EL-Naggar AK, Chan JKC, eds ; WHO classification of Head and Neck Tumours. IARC Press, Lyon, 2017, p189-190. – reference: 10) Sato N, Nakamura Y, et al : Case report: adrenal oncocytoma associated with markedly increased FDG uptake and immunohistochemically positive for GLUT1. Endocr Pathol 25: 410-415, 2014. – reference: 6) Sun G, Yang X, et al : The treatment of sublingual gland tumours. Int J Oral Maxillofac Surg 39: 863-868, 2010. – reference: 8) Kato H, Fujimoto K, et al : Usefulness of diffusionweighted MR imaging for differentiating between Warthin's tumor and oncocytoma of the parotid gland. Jpn J Radiol 35: 78-85, 2017. – reference: 11) 鬼頭良輔，海沼和幸，他：唾液腺癌の組織学的悪性度診断と予後予測におけるFDG-PETの有用性の検討．頭頸部癌 37: 73-77, 2011. – reference: 2) Zhou CX and Gao Y : Oncocytoma of the salivary glands: a clinicopathologic and immunohistochemical study. Oral Oncol 45: 232-238, 2009. – reference: 7) Lin Y, Wang Y, et al : Sublingual Gland Tumors Worldwide: A Descriptive Retrospective Study of 839 Cases. J Oral Maxillofac Surg 78: 1546-1556, 2020. |
| SSID | ssib005879736 ssib058493840 ssj0001742264 ssib000940266 |
| Score | 2.427811 |
| Snippet | We report a case of oncocytoma arising in the sublingual gland. The patient was a 53-year-old woman referred to our department because of a swelling in the... |
| SourceID | jstage |
| SourceType | Publisher |
| StartPage | 336 |
| SubjectTerms | オンコサイトーマ 粘表皮癌 舌下腺 舌下腺腫瘍 良性 |
| Title | 舌下腺に発生し診断に苦慮したオンコサイトーマの１例 |
| URI | https://www.jstage.jst.go.jp/article/jjoms/71/7/71_336/_article/-char/ja |
| Volume | 71 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | 日本口腔外科学会雑誌, 2025/07/20, Vol.71(7), pp.336-340 |
| journalDatabaseRights | – providerCode: PRVAFT databaseName: Open Access Digital Library customDbUrl: eissn: 2186-1579 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0001742264 issn: 0021-5163 databaseCode: KQ8 dateStart: 19670101 isFulltext: true titleUrlDefault: http://grweb.coalliance.org/oadl/oadl.html providerName: Colorado Alliance of Research Libraries |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrR1Na9RANJR68SKKit_04HhZUpNMJjNznGx3KRYFoYXeQj4PC7ai24u37VIo1Isgihd7ERHFXkSQUvwzKe3e_Au-NzO7m4qHWoQQ3r55n_M2mfeSzIzj3C3x3VIhMleWuXDDgqeuqALmll4V8Kooq6jE2cgPH0WLK-GDVbY6M3uv8dXSRj-bz1_8dV7JWaIKOIgrzpL9h8hOhAICYIgvnCHCcD5VjElHEAFHm3RCEgMQawwjsSIdCkkiUYDhREqNASAksmubJEdiJXRTRGRE1EKDS0tTETaBQNVpcBnAyAmIMrooianFTAE2pgktDVhridsWkGPJqKKLeOlrdzpgQDN11kZyopgG2kSBBEZElyhqvQbvAAO6wBdwVnEtiqFf6EiohYO1kshYNwk0XkyeE2ummMRSa1gAkhayx8AurWTRPUEcoX4kASBuWRrQiyiPiGhKHKGZ6KINlJEca-MNl5oSS-zCOEQVwgNHW9ogE0Ttchw0n9bAn97jbuBNri9NxXQPcfRV6OAr3anQJI3aCLVIpk1ScLT-Vw83R8LAd5lvB5dS43B7MtdnZnOf8ehoNsixdwHeGOoojRpZEzWLbv05IIOwEAfk3vqT5_Pcn58wnVji3F5AiSZLuJ9wPAFtMm7BKYhJD-qgcwGM3rhFy9LjRhkhQy9olCVMcMnp5Dfk2JKO1zTSz165nj9uvv4y3WDmxKC595vGQl7agypt_IWnTjqXLzoXbLU4p4x9l5yZXnrZWRptvzz8sTPa2q8HX47f7R-_3q0Hb0ef9o_efAXMaOfj0dYeYOrBbr35uR5-qzfh-F5vfqiH2_XwoB6-rwd7vw5eHf7cueKsdDvL7UXX7oni9gJIvd20EHkgRFp4fiplkEO5UAqW4dtvWtA0YCUk7NyrRC58mkZ-VPheTrOo5IIWlVfQq87s2vpaec2Zg0ouq8I8zUooo6DOkTRnOUuZl-ayEGV43RHG9-SpWfgmOXWcbpyd9aZzfnrd3HJm-882ytuQ9_ezOzrovwFf6c5X |
| linkProvider | Colorado Alliance of Research Libraries |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E8%88%8C%E4%B8%8B%E8%85%BA%E3%81%AB%E7%99%BA%E7%94%9F%E3%81%97%E8%A8%BA%E6%96%AD%E3%81%AB%E8%8B%A6%E6%85%AE%E3%81%97%E3%81%9F%E3%82%AA%E3%83%B3%E3%82%B3%E3%82%B5%E3%82%A4%E3%83%88%E3%83%BC%E3%83%9E%E3%81%AE%EF%BC%91%E4%BE%8B&rft.jtitle=%E6%97%A5%E6%9C%AC%E5%8F%A3%E8%85%94%E5%A4%96%E7%A7%91%E5%AD%A6%E4%BC%9A%E9%9B%91%E8%AA%8C&rft.au=%E7%AB%B9%E6%9D%91+%E5%BD%A9%E5%A4%8F&rft.au=%E7%A6%8F%E5%B6%8B+%E5%A4%A7%E5%B0%86&rft.au=%E6%A3%AE%E4%B8%8B+%E5%BB%A3%E5%A4%AA&rft.au=%E9%B3%B4%E7%80%AC+%E6%99%BA%E5%8F%B2&rft.date=2025-07-20&rft.pub=%E5%85%AC%E7%9B%8A%E7%A4%BE%E5%9B%A3%E6%B3%95%E4%BA%BA+%E6%97%A5%E6%9C%AC%E5%8F%A3%E8%85%94%E5%A4%96%E7%A7%91%E5%AD%A6%E4%BC%9A&rft.issn=0021-5163&rft.eissn=2186-1579&rft.volume=71&rft.issue=7&rft.spage=336&rft.epage=340&rft_id=info:doi/10.5794%2Fjjoms.71.336&rft.externalDocID=article_jjoms_71_7_71_336_article_char_ja |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0021-5163&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0021-5163&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0021-5163&client=summon |