舌下腺に発生し診断に苦慮したオンコサイトーマの１例

• Published in: 日本口腔外科学会雑誌 Vol. 71; no. 7; pp. 336 - 340
• Main Authors: 竹村 彩夏, 福嶋 大将, 森下 廣太, 鳴瀬 智史, 片瀬 直樹, 山田 朋弘
• Format: Journal Article
• Language: Japanese
• Published: 公益社団法人 日本口腔外科学会 20.07.2025
• Subjects: オンコサイトーマ; 粘表皮癌; 舌下腺; 舌下腺腫瘍; 良性
• ISSN: 0021-5163; 2186-1579
• DOI: 10.5794/jjoms.71.336

We report a case of oncocytoma arising in the sublingual gland. The patient was a 53-year-old woman referred to our department because of a swelling in the left oral floor. Magnetic resonance imaging revealed a mass with clear borders measuring approximately 25 × 20 mm in the left sublingual space, showing heterogeneous enhancement with contrast. The initial pathological diagnosis from a tissue biopsy was mucoepidermoid carcinoma. The patient underwent a tumor resection under general anesthesia. Pathological examinations showed that tumor cells consisted of proliferation of eosinophilic cells with granular cytoplasm, and immunohistochemistry revealed that the tumor cells showed a diffuse positive reaction for mitochondria. Based on these findings, the lesion was finally diagnosed as oncocytoma. No sign of recurrence has been observed one year and two months after surgery.