陽子線治療向け超電導加速器の技術動向

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Published in低温工学 Vol. 60; no. 3; pp. 60 - 67
Main Authors 江原, 悠太, 筒井, 裕士
Format Journal Article
LanguageJapanese
Published 公益社団法人 低温工学・超電導学会 (旧 社団法人 低温工学協会) 20.05.2025
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ISSN0389-2441
1880-0408
DOI10.2221/jcsj.60.60

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Author 江原, 悠太
筒井, 裕士
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References 26)H. Tsutsui, et al.: “Design study of a superconducting AVF cyclotron for proton therapy,” proc. CYC2013 (2013
7)S. Kojima and M. Hata: “Laser-driven ion accelerator,” in “Advances in Accelerators and Medical Physics,” Academic Press, (2023), pp.343-352
27)J. Yoshida, et al.: “Excitation test of superconducting magnet in 230-MeV isochronous cyclotron for proton therapy,” IEEE Transactions on Applied Superconductivity 30 (2019) 1-5
34)Leo Cancer Care: https://leocancercare.com/(Accessed 2025-1-31
28)Y. Ebara, et al.: “Field mapping system and field adjustment for a 230-MeV proton cyclotron,” Nuclear Instruments and Methods in Physics Research Section A 953 (2020) 163186
10)Y. Ebara, et al.: “First beam extraction from a superconducting azimuthally varying field cyclotron for proton therapy,” Nuclear Instruments and Methods in Physics Research Section A 1056 (2023) 168629
18)V. P. Derenchuk: “Application of Superconducting Technology for Proton Therapy,” Presented at NAPAC 2016 (Chicago, IL, USA
21)H. G. Blosser, et al.: “Proposal for a manufacturing prototype superconducting cyclotron for advanced cancer therapy,” MSUCL-874, Michigan State University (1993
32)B dot Medical: https://bdotmed.co.jp/(Accessed 2025-1-31
15)J. E. Jedediah, et al.: “Optimization of motion management parameters in a synchrotron-based spot scanning system,” Journal of Applied Clinical Medical Physics 20 (2019) 9
17)J. V. Minervini, et al.: “Compact, Low-Cost, Light-Weight, Superconducting, Ironless Cyclotrons for Hadron Radiotherapy,” Massachusetts Inst. of Technology, (2019
1)R. R. Wilson: “Radiological use of fast protons,” Radiology 47 (1946) 487-491
24)C. Wang, et al.: “The Commissioning of a 230 MeV Superconducting Cyclotron CYCIAE-230,” proc. CYC2022(2023
14)M. Umezawa, et al.: “Development of compact proton beam therapy system for moving organs,” Hitachi Review 64506 (2015
31)L. Brouwer, et al.: “Design of an achromatic superconducting magnet for a proton therapy gantry,” IEEE Transactions on Applied Superconductivity 27 (2016) 1-6
25)Y. Ebara, et al.: “Performance of cryogen-free superconducting magnet in isochronous cyclotron for proton therapy,” IEEE Transactions on Applied Superconductivity 33 (2023) 1-4
16)Hefei CIM-A: http://www.hfcim.com/ (Accessed 2025-1-31
筒井裕士ら:「粒子加速器のIEC規格化についての最近の動向」
35)P-Cure: https://www.p-cure.com/(Accessed 2025-01-31
20)T. A. Antaya: “Isochronous cyclotron with superconducting flutter coils and non-magnetic reinforcement,” U.S. Patent No. 9, 895, 552 (2018-02-20
11)F. Jiang, et al.: “Design study of a compact superconducting cyclotron SC240 for proton therapy,” proc. IPAC19 (2019
13)W. Kleeven, et al.: “The IBA superconducting synchrocyclotron project S2C2,” proc. CYC2013 (2013
19)H. Ueda, et al.: “Conceptual design of next generation HTS cyclotron,” IEEE Transactions on Applied Superconductivity 23 (2012) 4100205
22)T. A. Antaya: “High-field superconducting synchrocyclotron,” U.S. Patent. No. 7, 541, 905 (2009-1-2
30)J. Saini, et al.: “Commissioning a clinical proton pencil beam scanning beamline for pre-clinical ultra-high dose rate irradiations on a cyclotron-based system,” Frontiers in Oncology 14 (2024
36)H. Tsutsui, et al.,” Recent trends in IEC standardization of particle accelerators,” submitted. (in Japanese
3)Particle Therapy Co-Operative Group, https://www.ptcog.ch (Accessed 2025-1-31
33)L. Bottura, et al.: “Magnetic design of a compact GaToroid for very high energy electron and pre-clinical hadron beams,” IEEE Transactions on Applied Superconductivity 34.5 (2024) 1-5
5)A. Goto, T. Tachikawa, Y. Jongen, M. Schillo: “Comprehensive Biomedical Physics 8.12 Cyclotrons,” Elsevier, (2014) 179–195
23)G. Karamysheva, et al.: “Compact superconducting cyclotron SC200 for proton therapy,” proc. CYC2016 (2016
6)A. Degiovanni, et al.: “Design, integration, and commissioning of the first linac for image-guided hadron therapy prototype,” Physical Review Accelerators and Beams 27 (2024) 054701
4)J. M. Slater, et al: “The proton treatment center at Loma Linda University Medical Center: rationale for and description of its development,” International Journal of Radiation Oncology* Biology* Physics 22.2 (1992): 383-389
9)H. U. Klein, et al.: “Design, manufacturing and commissioning of compact superconducting 250 MeV cyclotrons for proton therapy: A short report from the field,” IEEE/CSC & ESAS European Superconductivity News Forum 2 (2007
12)Mevion Medical Systems: https://www.mevion.com (Accessed 2025-1-31
29)S. Jolly, et al.: “Technical challenges for FLASH proton therapy,” Physica Medica 78 (2020) 71-82
2)C. A. Tobias, et al.: “Pituitary irradiation with high-energy proton beams: A preliminary report,” Cancer Research 18 (1958) 121-134
8)T. Aoki, et al.: “Concept of frequency modulated variable-energy accelerator,” (2017
References_xml – reference: 34)Leo Cancer Care: https://leocancercare.com/(Accessed 2025-1-31)
– reference: 8)T. Aoki, et al.: “Concept of frequency modulated variable-energy accelerator,” (2017)
– reference: 5)A. Goto, T. Tachikawa, Y. Jongen, M. Schillo: “Comprehensive Biomedical Physics 8.12 Cyclotrons,” Elsevier, (2014) 179–195
– reference: 29)S. Jolly, et al.: “Technical challenges for FLASH proton therapy,” Physica Medica 78 (2020) 71-82
– reference: 11)F. Jiang, et al.: “Design study of a compact superconducting cyclotron SC240 for proton therapy,” proc. IPAC19 (2019)
– reference: 17)J. V. Minervini, et al.: “Compact, Low-Cost, Light-Weight, Superconducting, Ironless Cyclotrons for Hadron Radiotherapy,” Massachusetts Inst. of Technology, (2019)
– reference: 16)Hefei CIM-A: http://www.hfcim.com/ (Accessed 2025-1-31)
– reference: 4)J. M. Slater, et al: “The proton treatment center at Loma Linda University Medical Center: rationale for and description of its development,” International Journal of Radiation Oncology* Biology* Physics 22.2 (1992): 383-389
– reference: 1)R. R. Wilson: “Radiological use of fast protons,” Radiology 47 (1946) 487-491
– reference: 19)H. Ueda, et al.: “Conceptual design of next generation HTS cyclotron,” IEEE Transactions on Applied Superconductivity 23 (2012) 4100205
– reference: 14)M. Umezawa, et al.: “Development of compact proton beam therapy system for moving organs,” Hitachi Review 64506 (2015)
– reference: 33)L. Bottura, et al.: “Magnetic design of a compact GaToroid for very high energy electron and pre-clinical hadron beams,” IEEE Transactions on Applied Superconductivity 34.5 (2024) 1-5
– reference: 3)Particle Therapy Co-Operative Group, https://www.ptcog.ch (Accessed 2025-1-31)
– reference: 7)S. Kojima and M. Hata: “Laser-driven ion accelerator,” in “Advances in Accelerators and Medical Physics,” Academic Press, (2023), pp.343-352
– reference: 32)B dot Medical: https://bdotmed.co.jp/(Accessed 2025-1-31)
– reference: 18)V. P. Derenchuk: “Application of Superconducting Technology for Proton Therapy,” Presented at NAPAC 2016 (Chicago, IL, USA)
– reference: 22)T. A. Antaya: “High-field superconducting synchrocyclotron,” U.S. Patent. No. 7, 541, 905 (2009-1-2)
– reference: 25)Y. Ebara, et al.: “Performance of cryogen-free superconducting magnet in isochronous cyclotron for proton therapy,” IEEE Transactions on Applied Superconductivity 33 (2023) 1-4
– reference: 21)H. G. Blosser, et al.: “Proposal for a manufacturing prototype superconducting cyclotron for advanced cancer therapy,” MSUCL-874, Michigan State University (1993)
– reference: 15)J. E. Jedediah, et al.: “Optimization of motion management parameters in a synchrotron-based spot scanning system,” Journal of Applied Clinical Medical Physics 20 (2019) 9
– reference: 23)G. Karamysheva, et al.: “Compact superconducting cyclotron SC200 for proton therapy,” proc. CYC2016 (2016)
– reference: 10)Y. Ebara, et al.: “First beam extraction from a superconducting azimuthally varying field cyclotron for proton therapy,” Nuclear Instruments and Methods in Physics Research Section A 1056 (2023) 168629
– reference: 35)P-Cure: https://www.p-cure.com/(Accessed 2025-01-31)
– reference: 31)L. Brouwer, et al.: “Design of an achromatic superconducting magnet for a proton therapy gantry,” IEEE Transactions on Applied Superconductivity 27 (2016) 1-6
– reference: 36)H. Tsutsui, et al.,” Recent trends in IEC standardization of particle accelerators,” submitted. (in Japanese)
– reference: 12)Mevion Medical Systems: https://www.mevion.com (Accessed 2025-1-31)
– reference: 9)H. U. Klein, et al.: “Design, manufacturing and commissioning of compact superconducting 250 MeV cyclotrons for proton therapy: A short report from the field,” IEEE/CSC & ESAS European Superconductivity News Forum 2 (2007)
– reference: 26)H. Tsutsui, et al.: “Design study of a superconducting AVF cyclotron for proton therapy,” proc. CYC2013 (2013)
– reference: 28)Y. Ebara, et al.: “Field mapping system and field adjustment for a 230-MeV proton cyclotron,” Nuclear Instruments and Methods in Physics Research Section A 953 (2020) 163186
– reference: 20)T. A. Antaya: “Isochronous cyclotron with superconducting flutter coils and non-magnetic reinforcement,” U.S. Patent No. 9, 895, 552 (2018-02-20)
– reference: 24)C. Wang, et al.: “The Commissioning of a 230 MeV Superconducting Cyclotron CYCIAE-230,” proc. CYC2022(2023)
– reference: 27)J. Yoshida, et al.: “Excitation test of superconducting magnet in 230-MeV isochronous cyclotron for proton therapy,” IEEE Transactions on Applied Superconductivity 30 (2019) 1-5
– reference: 30)J. Saini, et al.: “Commissioning a clinical proton pencil beam scanning beamline for pre-clinical ultra-high dose rate irradiations on a cyclotron-based system,” Frontiers in Oncology 14 (2024)
– reference: 2)C. A. Tobias, et al.: “Pituitary irradiation with high-energy proton beams: A preliminary report,” Cancer Research 18 (1958) 121-134
– reference: 筒井裕士ら:「粒子加速器のIEC規格化についての最近の動向」
– reference: 6)A. Degiovanni, et al.: “Design, integration, and commissioning of the first linac for image-guided hadron therapy prototype,” Physical Review Accelerators and Beams 27 (2024) 054701
– reference: 13)W. Kleeven, et al.: “The IBA superconducting synchrocyclotron project S2C2,” proc. CYC2013 (2013)
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SubjectTerms proton beam therapy
superconducting accelerator
Title 陽子線治療向け超電導加速器の技術動向
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