COPDにおけるエネルギー消費と栄養

埼玉医科大学病院外来通院中のchronic obstructive pulmonary disease(COPD)およびハイリスク患者(n=36)において,二重標識水(doubly labeled water: DLW)法により総エネルギー消費量(total energy expenditure: TEE)を,間接熱量測定法により基礎代謝量(basal metabolic rate: BMR)を測定した.COPD患者でもBMRの増加はみられなかったが,Physical activity level(PAL=TEE/BMR)は重症・最重症では低下傾向を認めた(1.67).また,PALは軽強度およ...

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Published in日本呼吸ケア・リハビリテーション学会誌 Vol. 32; no. 3; pp. 306 - 312
Main Authors 仲村, 秀俊, 正木, 健司
Format Journal Article
LanguageJapanese
Published 一般社団法人 日本呼吸ケア・リハビリテーション学会 30.08.2024
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ISSN1881-7319
2189-4760
DOI10.15032/jsrcr.32.306

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Abstract 埼玉医科大学病院外来通院中のchronic obstructive pulmonary disease(COPD)およびハイリスク患者(n=36)において,二重標識水(doubly labeled water: DLW)法により総エネルギー消費量(total energy expenditure: TEE)を,間接熱量測定法により基礎代謝量(basal metabolic rate: BMR)を測定した.COPD患者でもBMRの増加はみられなかったが,Physical activity level(PAL=TEE/BMR)は重症・最重症では低下傾向を認めた(1.67).また,PALは軽強度および中強度の歩行以外の活動時間(p<0.01),6分間歩行距離および握力(p<0.001)と良好な相関を認めた.さらに,運動以外の身体活動量(nonexercise activity thermogenesis: NEAT)の評価法としてNEAT質問票が,エネルギー摂取量の推定法としてbrief-type self-administered diet history questionnaire(BDHQ)質問票が有用な可能性が示唆された.
AbstractList 埼玉医科大学病院外来通院中のchronic obstructive pulmonary disease(COPD)およびハイリスク患者(n=36)において,二重標識水(doubly labeled water: DLW)法により総エネルギー消費量(total energy expenditure: TEE)を,間接熱量測定法により基礎代謝量(basal metabolic rate: BMR)を測定した.COPD患者でもBMRの増加はみられなかったが,Physical activity level(PAL=TEE/BMR)は重症・最重症では低下傾向を認めた(1.67).また,PALは軽強度および中強度の歩行以外の活動時間(p<0.01),6分間歩行距離および握力(p<0.001)と良好な相関を認めた.さらに,運動以外の身体活動量(nonexercise activity thermogenesis: NEAT)の評価法としてNEAT質問票が,エネルギー摂取量の推定法としてbrief-type self-administered diet history questionnaire(BDHQ)質問票が有用な可能性が示唆された.
Author 正木, 健司
仲村, 秀俊
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References 3) Farooqi N, Carlsson M, Håglin L, et al.: Energy expenditure in women and men with COPD. Clin Nutr ESPEN 28: 171-178, 2018.
12) Morikawa K, Tabira K, Takemura H, et al.: A prediction equation to assess resting energy expenditure in Japanese patients with COPD. J Clin Med 9: 3455, 2020.
5) Shirahata T, Nishida Y, Sato H,et al.: Impact of non-exercise activity thermogenesis on physical activity in patients with COPD. Sci Prog 105: 368504221117064, 2022.
6) Nishida Y, Nakamura H, Sasaki S, et al.: Evaluation of energy intake by brief- type self- administered diet history questionnaire among male patients with stable/at risk for chronic obstructive pulmonary disease. BMJ Open Respir Res 8: e000807, 2021.
10) Donahoe M, Rogers RM, Wilson DO, et al.: Oxygen consumption of the respiratory muscles in normal and in malnourished patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 140: 385-391, 1989.
4) Sato H, Nakamura H, Nishida Y, et al.: Energy expenditure and physical activity in COPD by doubly labelled water method and an accelerometer. ERJ Open Res 7: 00407-2020, 2021.
2) Hugli O, Schutz Y, Fitting JW: The daily energy expenditure in stable chronic obstructive pulmonary disease. Am J Respir Crit Care Med 153: 294-300, 1996.
15) Pitta F, Troosters T, Spruit MA, et al.: Characteristics of physical activities in daily life in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 171: 972-977, 2005.
20) Kobayashi S, Yuan X, Sasaki S, et al.: Relative validity of brief-type self-administered diet history questionnaire among very old Japanese aged 80 years or older. Public Health Nutr 22: 212-222, 2019.
23) Ohfuji S, Fukushima W, Watanabe K, et al.: Pre-illness isoflavone consumption and disease risk of ulcerative colitis: a multicenter case-control study in Japan. PLoS One 9: e110270, 2014.
7) 「日本人の食事摂取基準」策定検討会:日本人の食事摂取基準(2020年版),p. 74, 79.https://www.mhlw.go.jp/content/10904750/000586553.pdf. Accessed: 17 June 2024.
8) Doré MF, Laaban JP, Orvoën-Frija E, et al.: Role of the thermic effect of food in malnutrition of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 155: 1535-1540, 1997.
1) Waschki B, Kirsten A, Holz O, et al.: Physical activity is the strongest predictor of all-cause mortality in patients with COPD: a prospective cohort study. Chest 140: 331-342, 2011.
17) Yamada Y, Hashii-Arishima Y, Yokoyama K, et al.: Validity of a triaxial accelerometer and simplified physical activity record in older adults aged 64-96 years: a doubly labeled water study. Eur J Appl Physiol 118: 2133-2146, 2018.
19) Hamasaki H, Yanai H, Mishima S, et al.: Correlations of non-exercise activity thermogenesis to metabolic parameters in Japanese patients with type 2 diabetes. Diabetol Metab Syndr 5: 26, 2013.
24) EBNJAPAN:佐々木式食習慣アセスメント(BDHQ/DHQ)支援のためのサイト.http://www.ebnjapan.org. Accessed: 17 June 2024.
13) Watz H, Waschki B, Boehme C, et al.: Extrapulmonary effects of chronic obstructive pulmonary disease on physical activity: a cross-sectional study. Am J Respir Crit Care Med 177: 743-751, 2008.
16) Minakata Y, Azuma Y, Sasaki S, et al.: Objective measurement of physical activity and sedentary behavior in patients with chronic obstructive pulmonary disease: points to keep in mind during evaluations. J Clin Med 12: 3254, 2023.
21) Oya J, Nakagami T, Sasaki S, et al.: Intake of n-3 polyunsaturated fatty acids and non-alcoholic fatty liver disease: a cross-sectional study in Japanese men and women. Eur J Clin Nutr 64: 1179-1185, 2010.
14) Watz H, Waschki B, Meyer T, et al.: Physical activity in patients with COPD. Eur Respir J 33: 262-272, 2009.
11) Sergia G, Coin A, Marin S, et al.: Body composition and resting energy expenditure in elderly male patients with chronic obstructive pulmonary disease. Respir Med 100: 1918-1924, 2006.
18) Hamasaki H, Yanai H, Kakei M, et al.: The validity of the non-exercise activity thermogenesis questionnaire evaluated by objectively measured daily physical activity by the triaxial accelerometer. BMC Sports Sci Med Rehabil 6: 27, 2014.
22) Fujii H, Iwase M, Ohkuma T, et al.: Impact of dietary fiber intake on glycemic control, cardiovascular risk factors and chronic kidney disease in Japanese patients with type 2 diabetes mellitus: the Fukuoka diabetes registry. Nutr J 12: 159, 2013.
9) 濱崎秀崇,栁内秀勝:肥満および代謝性疾患におけるNon exercise activity thermogenesis(NEAT)について.肥満研 21: 99-105, 2015.
References_xml – reference: 5) Shirahata T, Nishida Y, Sato H,et al.: Impact of non-exercise activity thermogenesis on physical activity in patients with COPD. Sci Prog 105: 368504221117064, 2022.
– reference: 12) Morikawa K, Tabira K, Takemura H, et al.: A prediction equation to assess resting energy expenditure in Japanese patients with COPD. J Clin Med 9: 3455, 2020.
– reference: 20) Kobayashi S, Yuan X, Sasaki S, et al.: Relative validity of brief-type self-administered diet history questionnaire among very old Japanese aged 80 years or older. Public Health Nutr 22: 212-222, 2019.
– reference: 11) Sergia G, Coin A, Marin S, et al.: Body composition and resting energy expenditure in elderly male patients with chronic obstructive pulmonary disease. Respir Med 100: 1918-1924, 2006.
– reference: 10) Donahoe M, Rogers RM, Wilson DO, et al.: Oxygen consumption of the respiratory muscles in normal and in malnourished patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 140: 385-391, 1989.
– reference: 14) Watz H, Waschki B, Meyer T, et al.: Physical activity in patients with COPD. Eur Respir J 33: 262-272, 2009.
– reference: 7) 「日本人の食事摂取基準」策定検討会:日本人の食事摂取基準(2020年版),p. 74, 79.https://www.mhlw.go.jp/content/10904750/000586553.pdf. Accessed: 17 June 2024.
– reference: 2) Hugli O, Schutz Y, Fitting JW: The daily energy expenditure in stable chronic obstructive pulmonary disease. Am J Respir Crit Care Med 153: 294-300, 1996.
– reference: 19) Hamasaki H, Yanai H, Mishima S, et al.: Correlations of non-exercise activity thermogenesis to metabolic parameters in Japanese patients with type 2 diabetes. Diabetol Metab Syndr 5: 26, 2013.
– reference: 13) Watz H, Waschki B, Boehme C, et al.: Extrapulmonary effects of chronic obstructive pulmonary disease on physical activity: a cross-sectional study. Am J Respir Crit Care Med 177: 743-751, 2008.
– reference: 16) Minakata Y, Azuma Y, Sasaki S, et al.: Objective measurement of physical activity and sedentary behavior in patients with chronic obstructive pulmonary disease: points to keep in mind during evaluations. J Clin Med 12: 3254, 2023.
– reference: 4) Sato H, Nakamura H, Nishida Y, et al.: Energy expenditure and physical activity in COPD by doubly labelled water method and an accelerometer. ERJ Open Res 7: 00407-2020, 2021.
– reference: 21) Oya J, Nakagami T, Sasaki S, et al.: Intake of n-3 polyunsaturated fatty acids and non-alcoholic fatty liver disease: a cross-sectional study in Japanese men and women. Eur J Clin Nutr 64: 1179-1185, 2010.
– reference: 17) Yamada Y, Hashii-Arishima Y, Yokoyama K, et al.: Validity of a triaxial accelerometer and simplified physical activity record in older adults aged 64-96 years: a doubly labeled water study. Eur J Appl Physiol 118: 2133-2146, 2018.
– reference: 22) Fujii H, Iwase M, Ohkuma T, et al.: Impact of dietary fiber intake on glycemic control, cardiovascular risk factors and chronic kidney disease in Japanese patients with type 2 diabetes mellitus: the Fukuoka diabetes registry. Nutr J 12: 159, 2013.
– reference: 15) Pitta F, Troosters T, Spruit MA, et al.: Characteristics of physical activities in daily life in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 171: 972-977, 2005.
– reference: 23) Ohfuji S, Fukushima W, Watanabe K, et al.: Pre-illness isoflavone consumption and disease risk of ulcerative colitis: a multicenter case-control study in Japan. PLoS One 9: e110270, 2014.
– reference: 24) EBNJAPAN:佐々木式食習慣アセスメント(BDHQ/DHQ)支援のためのサイト.http://www.ebnjapan.org. Accessed: 17 June 2024.
– reference: 9) 濱崎秀崇,栁内秀勝:肥満および代謝性疾患におけるNon exercise activity thermogenesis(NEAT)について.肥満研 21: 99-105, 2015.
– reference: 6) Nishida Y, Nakamura H, Sasaki S, et al.: Evaluation of energy intake by brief- type self- administered diet history questionnaire among male patients with stable/at risk for chronic obstructive pulmonary disease. BMJ Open Respir Res 8: e000807, 2021.
– reference: 8) Doré MF, Laaban JP, Orvoën-Frija E, et al.: Role of the thermic effect of food in malnutrition of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 155: 1535-1540, 1997.
– reference: 1) Waschki B, Kirsten A, Holz O, et al.: Physical activity is the strongest predictor of all-cause mortality in patients with COPD: a prospective cohort study. Chest 140: 331-342, 2011.
– reference: 18) Hamasaki H, Yanai H, Kakei M, et al.: The validity of the non-exercise activity thermogenesis questionnaire evaluated by objectively measured daily physical activity by the triaxial accelerometer. BMC Sports Sci Med Rehabil 6: 27, 2014.
– reference: 3) Farooqi N, Carlsson M, Håglin L, et al.: Energy expenditure in women and men with COPD. Clin Nutr ESPEN 28: 171-178, 2018.
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StartPage 306
SubjectTerms エネルギー消費
二重標識水法
基礎代謝量
慢性閉塞性肺疾患
栄養
身体活動量
運動以外の活動による熱産生
Title COPDにおけるエネルギー消費と栄養
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Volume 32
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