顎口腔領域の重症感染症への対応

The infection in the oral and maxillofacial regions is frequently observed on a daily basis, and most of them are odontogenic. Odontogenic infections are commonly the result of carious teeth with pulpal exposure, periodontitis, pericoronitis, or complications of dental procedures. They respond well...

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Published in日本口腔外科学会雑誌 Vol. 64; no. 7; pp. 394 - 403
Main Authors 古森, 孝英, 古土井, 春吾
Format Journal Article
LanguageJapanese
Published 社団法人 日本口腔外科学会 20.07.2018
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ISSN0021-5163
2186-1579
DOI10.5794/jjoms.64.394

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Abstract The infection in the oral and maxillofacial regions is frequently observed on a daily basis, and most of them are odontogenic. Odontogenic infections are commonly the result of carious teeth with pulpal exposure, periodontitis, pericoronitis, or complications of dental procedures. They respond well to current medical and surgical treatments. However, they can sometimes extend beyond the oral cavity, with serious consequences. Cellulitis in the oral and maxillofacial region can spread to deep neck spaces and possibly to the mediastinum. Computerized tomography play the important role in diagnosis of cellulitis. Fulminating infection in the head and neck may present as a rapidly progressive, potentially fatal condition characterized by extensive necrosis along the fascia of the neck. One form of such infection is necrotizing fasciitis. Early diagnosis and treatment is critical. The laboratory risk indicator for necrotizing fasciitis (LRINEC) score was a valuable assisted diagnosis tool. The keys to successful management of these infections are protection and control of the airway, intravenous antibiotic therapy and aggressive incision and surgical drainage. It is usually preferable to drain multi-space infections involving the sublingual, submental, submandibular, masseteric, pterygomandibular, and/or lateral pharyngeal spaces, as early as possible from an extraoral approach.
AbstractList The infection in the oral and maxillofacial regions is frequently observed on a daily basis, and most of them are odontogenic. Odontogenic infections are commonly the result of carious teeth with pulpal exposure, periodontitis, pericoronitis, or complications of dental procedures. They respond well to current medical and surgical treatments. However, they can sometimes extend beyond the oral cavity, with serious consequences. Cellulitis in the oral and maxillofacial region can spread to deep neck spaces and possibly to the mediastinum. Computerized tomography play the important role in diagnosis of cellulitis. Fulminating infection in the head and neck may present as a rapidly progressive, potentially fatal condition characterized by extensive necrosis along the fascia of the neck. One form of such infection is necrotizing fasciitis. Early diagnosis and treatment is critical. The laboratory risk indicator for necrotizing fasciitis (LRINEC) score was a valuable assisted diagnosis tool. The keys to successful management of these infections are protection and control of the airway, intravenous antibiotic therapy and aggressive incision and surgical drainage. It is usually preferable to drain multi-space infections involving the sublingual, submental, submandibular, masseteric, pterygomandibular, and/or lateral pharyngeal spaces, as early as possible from an extraoral approach.
Author 古森, 孝英
古土井, 春吾
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References 15) 楠元順哉, 古土井春吾, 他:頭頸部領域における壊死性筋膜炎に対するLRINEC score の有用性の検討.日口外誌 61: 505-512, 2015.
18) 金子明寛:口腔感染症に対する抗菌薬療法−新しい抗菌薬を中心に−.日口外誌 56: 546-552, 2010.
14) Petitpas F, Blancal JP, et al : Factors associated with the mediastinal spread of cervical necrotizing fasciitis. Ann Thorac Surg 93: 234-238, 2012.
5) 楠元順哉, 古土井春吾:歯性感染症から頸部腫脹, 嚥下痛, 開口障害, 呼吸苦, 全身倦怠感を生じた1例.日化療会誌 64: 550-559, 2016.
6) 國行秀一, 前川直輝, 他:壊死性筋膜炎11例の統計的観察.日皮会誌 118: 1511-1517, 2008.
1) 金子明寛, 青木隆幸, 他:JAID/JCS ガイドライン2016 −歯性感染症−.日化療会誌 64: 641-646, 2016.
8) 石川耕資, 南本俊之, 他:壊死性筋膜炎と重症蜂窩織炎の鑑別診断におけるLRINEC score の有用性の検討.創傷 5: 22-26, 2014.
7) 日本化学療法学会, 日本嫌気性菌感染症研究会 編:嫌気性菌感染症 診断・治療ガイドライン.第1版,協和企画, 東京, 2007, 88-100 頁
20) 山本美朗:遠隔の組織隙・器官への炎症の波及.北野繁雄, 山本美朗 編;これからの口腔感染症.第1版 (第3刷).学建書院, 東京, 2002, 88-91 頁
11) Lazow SK : Orofacial infections in the 21st century. N Y State Dent J 71: 36-41, 2005.
10) 土田哲也:重症皮膚・軟部組織感染症 (壊死性筋膜炎など) の鑑別と対処法.日皮会雑 120: 11-14, 2010.
4) 高橋淳子, 古土井春吾, 他:顎口腔領域の重症感染症例の検討.口腔感染症誌 24: 14-20, 2017.
19) 兼松宣武:組織隙に侵攻した歯性感染症.北野繁雄, 山本美朗 編;これからの口腔感染症.第1版 (第3刷).学建書院, 東京, 2002, 71-88 頁
12) Banerjee AR, Zbären P, et al : Cervical necrotizing Fasciitis : a distinct clinicopathological entity? J Laryngol Otol 110: 81-86, 1996.
16) 古土井春吾, 古森孝英:炎症性疾患の治療 (消炎療法).榎本昭二, 道 健一, 他 監修;最新口腔外科学.第5版, 医歯薬出版, 東京, 2017, 741-750 頁
13) Huang TT, Liu TC, et al : Deep neck infection : analysis of 185 cases. Head Neck 26: 854-860, 2004.
3) 藤田清秀:第5章主要な歯科口腔外科疾患 A. 齲蝕 2. 齲蝕の継発症.藤田清秀編;日本臨床内科医会叢書5 −内科医に必要な口腔疾患の知識−.第1版, 文光堂, 東京, 2003, 58-62 頁
2) 金子明寛:歯科・口腔外科感染症.日本感染症学会・日本化学療法学会編, 抗菌薬使用のガイドライン.協和企画, 東京, 2005, 213-216 頁
17) 金子明寛:歯性感染症における抗菌薬の使い方.日本化学療法学会 抗菌化学療法認定医認定制度審議委員会 編;抗菌薬適正使用生涯教育テキスト.改訂版, 杏林舎, 東京, 2013, 294-303 頁
9) 河西浩一, 眞鍋紀子, 他:糖尿病における重症感染症−本邦報告例568例の集計−.香川県立医療短期大学紀要 1: 1-10, 1999.
References_xml – reference: 15) 楠元順哉, 古土井春吾, 他:頭頸部領域における壊死性筋膜炎に対するLRINEC score の有用性の検討.日口外誌 61: 505-512, 2015.
– reference: 10) 土田哲也:重症皮膚・軟部組織感染症 (壊死性筋膜炎など) の鑑別と対処法.日皮会雑 120: 11-14, 2010.
– reference: 17) 金子明寛:歯性感染症における抗菌薬の使い方.日本化学療法学会 抗菌化学療法認定医認定制度審議委員会 編;抗菌薬適正使用生涯教育テキスト.改訂版, 杏林舎, 東京, 2013, 294-303 頁.
– reference: 11) Lazow SK : Orofacial infections in the 21st century. N Y State Dent J 71: 36-41, 2005.
– reference: 2) 金子明寛:歯科・口腔外科感染症.日本感染症学会・日本化学療法学会編, 抗菌薬使用のガイドライン.協和企画, 東京, 2005, 213-216 頁.
– reference: 5) 楠元順哉, 古土井春吾:歯性感染症から頸部腫脹, 嚥下痛, 開口障害, 呼吸苦, 全身倦怠感を生じた1例.日化療会誌 64: 550-559, 2016.
– reference: 13) Huang TT, Liu TC, et al : Deep neck infection : analysis of 185 cases. Head Neck 26: 854-860, 2004.
– reference: 7) 日本化学療法学会, 日本嫌気性菌感染症研究会 編:嫌気性菌感染症 診断・治療ガイドライン.第1版,協和企画, 東京, 2007, 88-100 頁.
– reference: 3) 藤田清秀:第5章主要な歯科口腔外科疾患 A. 齲蝕 2. 齲蝕の継発症.藤田清秀編;日本臨床内科医会叢書5 −内科医に必要な口腔疾患の知識−.第1版, 文光堂, 東京, 2003, 58-62 頁.
– reference: 20) 山本美朗:遠隔の組織隙・器官への炎症の波及.北野繁雄, 山本美朗 編;これからの口腔感染症.第1版 (第3刷).学建書院, 東京, 2002, 88-91 頁.
– reference: 1) 金子明寛, 青木隆幸, 他:JAID/JCS ガイドライン2016 −歯性感染症−.日化療会誌 64: 641-646, 2016.
– reference: 19) 兼松宣武:組織隙に侵攻した歯性感染症.北野繁雄, 山本美朗 編;これからの口腔感染症.第1版 (第3刷).学建書院, 東京, 2002, 71-88 頁.
– reference: 4) 高橋淳子, 古土井春吾, 他:顎口腔領域の重症感染症例の検討.口腔感染症誌 24: 14-20, 2017.
– reference: 9) 河西浩一, 眞鍋紀子, 他:糖尿病における重症感染症−本邦報告例568例の集計−.香川県立医療短期大学紀要 1: 1-10, 1999.
– reference: 6) 國行秀一, 前川直輝, 他:壊死性筋膜炎11例の統計的観察.日皮会誌 118: 1511-1517, 2008.
– reference: 18) 金子明寛:口腔感染症に対する抗菌薬療法−新しい抗菌薬を中心に−.日口外誌 56: 546-552, 2010.
– reference: 8) 石川耕資, 南本俊之, 他:壊死性筋膜炎と重症蜂窩織炎の鑑別診断におけるLRINEC score の有用性の検討.創傷 5: 22-26, 2014.
– reference: 12) Banerjee AR, Zbären P, et al : Cervical necrotizing Fasciitis : a distinct clinicopathological entity? J Laryngol Otol 110: 81-86, 1996.
– reference: 14) Petitpas F, Blancal JP, et al : Factors associated with the mediastinal spread of cervical necrotizing fasciitis. Ann Thorac Surg 93: 234-238, 2012.
– reference: 16) 古土井春吾, 古森孝英:炎症性疾患の治療 (消炎療法).榎本昭二, 道 健一, 他 監修;最新口腔外科学.第5版, 医歯薬出版, 東京, 2017, 741-750 頁.
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SubjectTerms 壊死性筋膜炎
外科的ドレナージ
歯性感染症
蜂窩織炎
Title 顎口腔領域の重症感染症への対応
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