末梢神経障害を伴ったeosinophilic fasciitisの1例
症例は17才,男性. 13才時,運動後に両側前腕の発赤,疼痛を伴う腫脹が出現,その後両側膝関節周囲の炎症が出現し,以後症状の消長を繰り返す. 15才時,四肢末端の知覚障害,四肢の運動後脱力症状が出現. 16才時,当科入院となる.末梢血に軽度の好酸球増加および血清lgEの高値を認めるも,その他の検査所見は正常であった.左前腕の筋生検にて治癒過程にある筋膜の炎症性変化が認められ, eosinophilic fasciitisと診断された.また神経には組織学的に異常所見を認めなかった.ステロイドホルモンを投与するも著効なく,免疫抑制薬にも一時的に反応するのみであった.末梢神経障害を伴う点とも併せて,...
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| Published in | 日本内科学会雑誌 Vol. 77; no. 3; pp. 370 - 374 |
|---|---|
| Main Authors | , , , , , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
一般社団法人 日本内科学会
1988
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| Online Access | Get full text |
| ISSN | 0021-5384 1883-2083 |
| DOI | 10.2169/naika.77.370 |
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| Abstract | 症例は17才,男性. 13才時,運動後に両側前腕の発赤,疼痛を伴う腫脹が出現,その後両側膝関節周囲の炎症が出現し,以後症状の消長を繰り返す. 15才時,四肢末端の知覚障害,四肢の運動後脱力症状が出現. 16才時,当科入院となる.末梢血に軽度の好酸球増加および血清lgEの高値を認めるも,その他の検査所見は正常であった.左前腕の筋生検にて治癒過程にある筋膜の炎症性変化が認められ, eosinophilic fasciitisと診断された.また神経には組織学的に異常所見を認めなかった.ステロイドホルモンを投与するも著効なく,免疫抑制薬にも一時的に反応するのみであった.末梢神経障害を伴う点とも併せて,貴重な症例と考え報告した. |
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| AbstractList | 症例は17才,男性. 13才時,運動後に両側前腕の発赤,疼痛を伴う腫脹が出現,その後両側膝関節周囲の炎症が出現し,以後症状の消長を繰り返す. 15才時,四肢末端の知覚障害,四肢の運動後脱力症状が出現. 16才時,当科入院となる.末梢血に軽度の好酸球増加および血清lgEの高値を認めるも,その他の検査所見は正常であった.左前腕の筋生検にて治癒過程にある筋膜の炎症性変化が認められ, eosinophilic fasciitisと診断された.また神経には組織学的に異常所見を認めなかった.ステロイドホルモンを投与するも著効なく,免疫抑制薬にも一時的に反応するのみであった.末梢神経障害を伴う点とも併せて,貴重な症例と考え報告した. |
| Author | 黒尾, 誠 高野, 清豪 寺井, 千尋 世古, 義規 富谷, 智明 高久, 史麿 清水, 輝夫 野島, 美久 山田, 明 井上, 聖啓 |
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| References | 3) Rodnan GP, et al: Eosinophilic fasciitis: Report of 7 cases of a newly recognized scleroderma-like syndrome. Arthritis Rheum 18: 422, 1975. 9) Michet CJ, et al: Eosinophilic fasciitis: Report of 15 cases. Mayo Clin Proc 56: 27, 1981. 13) Nawata Y, et al: Eosinophilic fasciitis with autoimmune features. Arthritis Rheum 26: 688, 1983. 17) Nassonova VA, et al: Eosinophilic fasciitis. Review and report of six cases. Scand J Rheumatol 8: 225, 1979. 5) Moutsopoulos HM, et al: Diffuse fasciitis with eosinophilia. A clinicopathologic study. Amer J Med 68: 701, 1980. 20) Garcia-Morteo 0, et al: Cimetidine and eosinophilic fasciitis. Ann Intern Med 100: 318, 1984. 19) Laso FJ, et al: Cimetidine and eosinophilic fasciitis. Ann Intern Med 98: 1026, 1983. 18) Solomon G, et al: Eosinophilic fasciitis responsive to cimetidine. Ann Intern Med 97: 547, 1982. 12) Kent LT, et al: Eosinophilic fasciitis: Clinical, laboratory, and microscopic considerations. Arthritis Rheum 24: 677, 1981. 15) Bennett RM, et al: Eosinophilic fasciitis: Case report and review of the literature. Ann Rheum Dis 36: 354, 1977. 2) Shulman LE: Diffuse fasciitis with eosinophilia: A new syndrome? Trans Assoc AmerPhysicians 88: 70, 1975. 16) Chan MKL, Lagas W: Eosinophilic fasciitis, viceral involvement. Arch Intern Med 142: 2201, 1982. 4) Fu TS, et al: Eosinophilic fasciitis. JAMA 240: 451, 1978. 14) Yamane K, et al: Eosinophilic fasciitis with prominent immunologic abnormalities. Jpn J Med 22: 134, 1983. 6) Sibrack LA, et al: Eosinophilic fasciitis. Clinics in rheumatic diseases. WB Saunders Co Ltd 8: 443, 1982. 10) Michael B, et al: Capillary microscopy in eosinophilic fasciitis. A comparison with systemic sclerosis. Arthritis Rheum 26: 617, 1983. 7) 野島美久,他: Eosinophilic fasciitis.内科58: 940, 1986. 8) Barnes L, et al: Eosinophilic fasciitis: A pathologic study of twenty cases. Amer J Path ol 96: 493, 1979. 1) Shulman LE: Diffuse fasciitis with hypergammaglobulinemia and eosinophilia: A new syndrome? J Rheumatol 1(Suppl 1): 82, 1974. 11) Abeles M, et al: Eosinophilic fasciitis: A clinicopathologic study. Arch Intern Med 139: 586, 1979. |
| References_xml | – reference: 2) Shulman LE: Diffuse fasciitis with eosinophilia: A new syndrome? Trans Assoc AmerPhysicians 88: 70, 1975. – reference: 15) Bennett RM, et al: Eosinophilic fasciitis: Case report and review of the literature. Ann Rheum Dis 36: 354, 1977. – reference: 16) Chan MKL, Lagas W: Eosinophilic fasciitis, viceral involvement. Arch Intern Med 142: 2201, 1982. – reference: 14) Yamane K, et al: Eosinophilic fasciitis with prominent immunologic abnormalities. Jpn J Med 22: 134, 1983. – reference: 1) Shulman LE: Diffuse fasciitis with hypergammaglobulinemia and eosinophilia: A new syndrome? J Rheumatol 1(Suppl 1): 82, 1974. – reference: 4) Fu TS, et al: Eosinophilic fasciitis. JAMA 240: 451, 1978. – reference: 11) Abeles M, et al: Eosinophilic fasciitis: A clinicopathologic study. Arch Intern Med 139: 586, 1979. – reference: 12) Kent LT, et al: Eosinophilic fasciitis: Clinical, laboratory, and microscopic considerations. Arthritis Rheum 24: 677, 1981. – reference: 17) Nassonova VA, et al: Eosinophilic fasciitis. Review and report of six cases. Scand J Rheumatol 8: 225, 1979. – reference: 3) Rodnan GP, et al: Eosinophilic fasciitis: Report of 7 cases of a newly recognized scleroderma-like syndrome. Arthritis Rheum 18: 422, 1975. – reference: 7) 野島美久,他: Eosinophilic fasciitis.内科58: 940, 1986. – reference: 13) Nawata Y, et al: Eosinophilic fasciitis with autoimmune features. Arthritis Rheum 26: 688, 1983. – reference: 8) Barnes L, et al: Eosinophilic fasciitis: A pathologic study of twenty cases. Amer J Path ol 96: 493, 1979. – reference: 9) Michet CJ, et al: Eosinophilic fasciitis: Report of 15 cases. Mayo Clin Proc 56: 27, 1981. – reference: 18) Solomon G, et al: Eosinophilic fasciitis responsive to cimetidine. Ann Intern Med 97: 547, 1982. – reference: 20) Garcia-Morteo 0, et al: Cimetidine and eosinophilic fasciitis. Ann Intern Med 100: 318, 1984. – reference: 5) Moutsopoulos HM, et al: Diffuse fasciitis with eosinophilia. A clinicopathologic study. Amer J Med 68: 701, 1980. – reference: 19) Laso FJ, et al: Cimetidine and eosinophilic fasciitis. Ann Intern Med 98: 1026, 1983. – reference: 6) Sibrack LA, et al: Eosinophilic fasciitis. Clinics in rheumatic diseases. WB Saunders Co Ltd 8: 443, 1982. – reference: 10) Michael B, et al: Capillary microscopy in eosinophilic fasciitis. A comparison with systemic sclerosis. Arthritis Rheum 26: 617, 1983. |
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| Snippet | 症例は17才,男性. 13才時,運動後に両側前腕の発赤,疼痛を伴う腫脹が出現,その後両側膝関節周囲の炎症が出現し,以後症状の消長を繰り返す. 15才時,四肢末端の知覚障害,四... |
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| Title | 末梢神経障害を伴ったeosinophilic fasciitisの1例 |
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