NSIPの組織像を呈し反復する気胸を伴った慢性過敏性肺臓炎の1例

38歳,女性.乾性咳嗽,労作時呼吸困難を主訴に受診.胸部X線写真上両側上肺野優位の網状影,胸部CT所見上不均一な淡い濃度上昇を認めた.肺生検組織はNonspecific interstitial pneumonia (NSIP)類似の病理像を呈し,病歴とあわせ慢性過敏性肺臓炎と診断しPrednisolone (PSL)投与を開始した.また両側性の反復する気胸を認めた.慢性過敏性肺臓炎における反復性気胸の報告は少なく貴重な症例と考えられた....

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Published in日本内科学会雑誌 Vol. 92; no. 2; pp. 310 - 312
Main Authors 吉見, 通洋, 萩本, 直樹, 桑野, 和善, 井上, 博之, 原, 信之, 出水, みいる, 山崎, 尚美
Format Journal Article
LanguageJapanese
Published 一般社団法人 日本内科学会 10.02.2003
Subjects
慢性過敏性肺臓炎
気胸
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ISSN0021-5384
1883-2083
DOI10.2169/naika.92.310

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Abstract 38歳,女性.乾性咳嗽,労作時呼吸困難を主訴に受診.胸部X線写真上両側上肺野優位の網状影,胸部CT所見上不均一な淡い濃度上昇を認めた.肺生検組織はNonspecific interstitial pneumonia (NSIP)類似の病理像を呈し,病歴とあわせ慢性過敏性肺臓炎と診断しPrednisolone (PSL)投与を開始した.また両側性の反復する気胸を認めた.慢性過敏性肺臓炎における反復性気胸の報告は少なく貴重な症例と考えられた.
AbstractList 38歳,女性.乾性咳嗽,労作時呼吸困難を主訴に受診.胸部X線写真上両側上肺野優位の網状影,胸部CT所見上不均一な淡い濃度上昇を認めた.肺生検組織はNonspecific interstitial pneumonia (NSIP)類似の病理像を呈し,病歴とあわせ慢性過敏性肺臓炎と診断しPrednisolone (PSL)投与を開始した.また両側性の反復する気胸を認めた.慢性過敏性肺臓炎における反復性気胸の報告は少なく貴重な症例と考えられた.
Author 萩本, 直樹
原, 信之
出水, みいる
桑野, 和善
吉見, 通洋
山崎, 尚美
井上, 博之
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References 5) Vincent C, et al: Nonspecific interstitial pneumonia: individualization of a clinicopathologic entity in a series of 12 patients. Am J Respir Crit Care Med 168: 1286-1293, 1998.
3) 斉藤司,他:慢性過敏性肺臓炎の臨床.日胸臨 56: 648-654, 1997.
9) Kryda MJ, Emanuel DA: Farmer's lung disease and other hypersensitivity pneumonitis. Fungal Diseases Lung 902-907, 1986.
6) Jacobs RL et al: Organic antigen-induced interstitial lung disease: diagnosis and management. Ann Allergy Asthma Immunol 88: 30-41. 2002.
7) 吉川隆志,他:高度の肺線維症に進展し,自然気胸を生じた農夫肺症の1例.日胸疾会誌 32: 902-907, 1994.
2) Hapke EJ, et al: Farmer's lung. A clinical, radiographic, functional, and serological correlation of acute and chronic stages. Thorax 23: 451-468, 1968
8) 山口修二,他:両側気胸と縦隔気腫を合併した農夫肺の1例.日胸疾会誌 35: 650-655, 1997.
1) 安藤正幸:過敏性肺臓炎,呼吸器疾患.原澤道美,他編.初版,医歯薬出版,東京, 1994. 363-367.
4) Katzenstein ALA, RF Fiorelli: Nonspecific interstitial pneumonia/fibrosis: histological features and clinical significance. Am J Surg Pathol 18: 136-147, 1994.
10) Maruyama J, et al: Lung fibrosis in hypersensitivity pneumonitis. Association with CD4+ but not CD8+ cell dominant alveolitis and insidious onset. Chest 104: 38-43, 1993.
References_xml – reference: 1) 安藤正幸:過敏性肺臓炎,呼吸器疾患.原澤道美,他編.初版,医歯薬出版,東京, 1994. 363-367.
– reference: 4) Katzenstein ALA, RF Fiorelli: Nonspecific interstitial pneumonia/fibrosis: histological features and clinical significance. Am J Surg Pathol 18: 136-147, 1994.
– reference: 2) Hapke EJ, et al: Farmer's lung. A clinical, radiographic, functional, and serological correlation of acute and chronic stages. Thorax 23: 451-468, 1968
– reference: 10) Maruyama J, et al: Lung fibrosis in hypersensitivity pneumonitis. Association with CD4+ but not CD8+ cell dominant alveolitis and insidious onset. Chest 104: 38-43, 1993.
– reference: 6) Jacobs RL et al: Organic antigen-induced interstitial lung disease: diagnosis and management. Ann Allergy Asthma Immunol 88: 30-41. 2002.
– reference: 9) Kryda MJ, Emanuel DA: Farmer's lung disease and other hypersensitivity pneumonitis. Fungal Diseases Lung 902-907, 1986.
– reference: 7) 吉川隆志,他:高度の肺線維症に進展し,自然気胸を生じた農夫肺症の1例.日胸疾会誌 32: 902-907, 1994.
– reference: 3) 斉藤司,他:慢性過敏性肺臓炎の臨床.日胸臨 56: 648-654, 1997.
– reference: 5) Vincent C, et al: Nonspecific interstitial pneumonia: individualization of a clinicopathologic entity in a series of 12 patients. Am J Respir Crit Care Med 168: 1286-1293, 1998.
– reference: 8) 山口修二,他:両側気胸と縦隔気腫を合併した農夫肺の1例.日胸疾会誌 35: 650-655, 1997.
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SubjectTerms 慢性過敏性肺臓炎
気胸
Title NSIPの組織像を呈し反復する気胸を伴った慢性過敏性肺臓炎の1例
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