非閉塞性肥大型心筋症の体表面電位図所見

肥大型心筋症患者における心電図変化の特徴を正常群との隔たりを表現するdeparture mapを作成して検討した.対象は心エコー図にて中隔厚13mmをこえる肥大型心筋症患者24名で, この疾患群を後壁厚13mm以下のA群16名と13mmをこえるB群8名とに分類した.体表面電位図は87誘導点より記録, 各誘導点のQRS波形につき, (1) QRS開始より10, 20, 30, 40, 50, 60mseoの各電位, (2) QRS波形の時間積分値AQRS, (3) 心室興奮到達時間VATを求めた.Departure index (DI) を〔 (各計測値一正常群より求めた平均値) /正常群より求...

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Published in心電図 Vol. 12; no. 3; pp. 299 - 309
Main Authors 八巻, 通安, 中村, 和治, 安井, 昭二, 立木, 楷
Format Journal Article
LanguageJapanese
Published 一般社団法人 日本不整脈心電学会 1992
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ISSN0285-1660
1884-2437
DOI10.5105/jse.12.299

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Abstract 肥大型心筋症患者における心電図変化の特徴を正常群との隔たりを表現するdeparture mapを作成して検討した.対象は心エコー図にて中隔厚13mmをこえる肥大型心筋症患者24名で, この疾患群を後壁厚13mm以下のA群16名と13mmをこえるB群8名とに分類した.体表面電位図は87誘導点より記録, 各誘導点のQRS波形につき, (1) QRS開始より10, 20, 30, 40, 50, 60mseoの各電位, (2) QRS波形の時間積分値AQRS, (3) 心室興奮到達時間VATを求めた.Departure index (DI) を〔 (各計測値一正常群より求めた平均値) /正常群より求めた標準偏差〕の式にて算出, DIの体表面分布をdeparture mapとして表現した.DI≧2を+2SDareaとし異常正領域と考えた.A群, B群の相違は50・60mseo, AQRS, VATにて明瞭であり, それぞれのdeparture map上の+2SD areaは, A群では左前胸部上方・側胸部上方に, B群では左前胸部から側胸部・背部にかけて広範に出現した.心筋の肥大部位がdeparture mapに表現され, その推定が可能と考えられた.また, 50, 60mseo, AQRS, VATの各departure map上の+2SD areaの面積と, 壁厚和 (中隔厚+後壁厚) は, それぞれr=0.63~0.81の相関を示し心筋肥大の程度も推定可能と考えられた.肥大型心筋症の心電図変化の特徴は, 心筋の肥大部位に対応した心起電力の増大と心室興奮伝播遅延と考えられた.
AbstractList 肥大型心筋症患者における心電図変化の特徴を正常群との隔たりを表現するdeparture mapを作成して検討した.対象は心エコー図にて中隔厚13mmをこえる肥大型心筋症患者24名で, この疾患群を後壁厚13mm以下のA群16名と13mmをこえるB群8名とに分類した.体表面電位図は87誘導点より記録, 各誘導点のQRS波形につき, (1) QRS開始より10, 20, 30, 40, 50, 60mseoの各電位, (2) QRS波形の時間積分値AQRS, (3) 心室興奮到達時間VATを求めた.Departure index (DI) を〔 (各計測値一正常群より求めた平均値) /正常群より求めた標準偏差〕の式にて算出, DIの体表面分布をdeparture mapとして表現した.DI≧2を+2SDareaとし異常正領域と考えた.A群, B群の相違は50・60mseo, AQRS, VATにて明瞭であり, それぞれのdeparture map上の+2SD areaは, A群では左前胸部上方・側胸部上方に, B群では左前胸部から側胸部・背部にかけて広範に出現した.心筋の肥大部位がdeparture mapに表現され, その推定が可能と考えられた.また, 50, 60mseo, AQRS, VATの各departure map上の+2SD areaの面積と, 壁厚和 (中隔厚+後壁厚) は, それぞれr=0.63~0.81の相関を示し心筋肥大の程度も推定可能と考えられた.肥大型心筋症の心電図変化の特徴は, 心筋の肥大部位に対応した心起電力の増大と心室興奮伝播遅延と考えられた.
Author 八巻, 通安
安井, 昭二
立木, 楷
中村, 和治
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References 9) Flowers NC, Horan LG, Johnson JC : Anterior infarctional changes occurring during mid and late ventricular activation detectable by surface mapping techniques. Circulation 54 906, 1976
4) Frank S, Braunwald E : Idiopathic hypertrophic sobaortic stenosis. Clinical analysis of 126 patients with emphasis on the natural history. Circulation 37 : 759, 1968
10) Ikeda K, Kubota I, Tonooka I, Tsuiki K, Yasui S : Detection of posterior myocardial infarction by body surface mapping : A comparative study with 12 lead ECG and VCG. J Electrocardiol 18: 361, 1985
13) Ikeda K, Kubota I, Igarashi A, Yamaki M, Tsuiki K, Yasui S : Detection of abnormalities in ventricular activation sequence by body surface isochrone mapping in patients with previous myocardial infarction. Circulation 72 : 801, 1985
1) Toshima H, Koga Y, Kimura N : Correlations between electrocardiographic, ventricurographic and echocardiographic findings in patients with left ventricular overload. Am Heart j 79 : 547, 1977
5) Savage DD, Seides SF, Clark CE, Henry WL, Maron BJ, Robinson FC, Epstein SE : Electrocardiographic findings in patients with obstructive and nonobstructive hypertrophic cardiomyopathy. Circulation 54 : 402, 1978
6) 石川富久, 林博史, 上松治儀, 小島春紀, 外畑厳, 安井昭二: 体表面電位図による中隔肥大の定性的および定量的評価. 呼と循29: 545, 1981
12) Montague TJ, Smith ER, Cameron DA, Rautaharju PM, Klassen GA, Fehnington GS, Horacek BM : Isointegral analysis of body surface maps : surface distribution and temporal variability in normal subjects. Circulation 63 1166, 1981
14) Okajima M, Doniwa K, Ishikawa T, Niimi N, Koike Y : On body surface VAT isochrone maps generated by computer using simulated excitation sequences in ventricular model. Proceedings of Computers in Cardiology, October 1980, Williamsburg, VA, 1981, 187
15) Watanabe T, Toyama J, Toyoshima H, Oguri H, Ohno M, Ohta T, Okajima M, Naito Y, Yamada K : A practical microcomputer based mapping system for body surface, precordium, and epicardium. Comput Biomed Res 14 341, 1981
21) Cohen A, Hagan AD, Watkins J, Mitas J, Schvartzman M, Mazzoreni A, Cohen IM, Warren SE, Viebeg WV : Clinical correlates in hypertensive patients with left ventricular hypertrophy diagnosed with echocardiography. Am J Cardiol 47 : 335, 1981
17) Horan LG, Flowers NC, Brody DA : Body surface potential distribution : Comparison of naturally and artificially produced signals as analyzed by digital computer. Cir Res 13 373, 1963
18) Abildskov JA, Burgess MJ, Lux RL, Wyatt RF : Experimental evidence for regional cardiac influence in body surface isopotential maps of dogs. Cir Res 38 : 386, 1976
20) Scher AM, Young AC, Malgren AL, Erickson RV : Activation of the inter ventricular septum. Cir Res 3 : 56, 1955
2) Estes EH, Whalen RE, Reberts SR, Mckintosh HD: The electrocardiographic findings in idiopathic hypertrophic subaortic stenosis. Am Heart J 65 : 155, 1963
7) 林博史, 石川富久, 上松治儀, 小島春紀, 稲垣晴夫, 河合直樹, 外畑巌: 心尖部肥大型心筋症の体表面電位分布の特徴と定量的評価. 日内会誌71: 647, 1982
8) Yoshida H, Imataki K, Nagahana H, Ihoriya F, Nakao Y, Saito D, Haraoka S : Cardiac hypertrophic cardiomyopathy and hypertension evaluated by echocardiography and body surface isopotential mapping. J Cardiography 16 : 399, 1986
22) Safer ME, Lehner JP, Vincent MI, Plainfosse MT, Simon ACh : Echocardiographic dimensions in borderline and sustained hypertension. Am J Cardiol 44 : 930, 1979
3) Horrister RM, Goodwin JF : The electrocardiogram in cardiomyopathy. Br Heart J 25: 357, 1963
11) Tonooka I, Kubota I, Watanabe Y, Tsuiki K, Yasui S : Isointegral analysis of body surface maps for the assessment of location and size of myocardial infarction. Am J Cardiol 52 1174, 1983
16) Sahn DJ, DeMaria A, Kisslo J, Weyman A : Committee on M-mode Standarization of the American Society of Echocardiography : Recommendations regarding quantification in M-mode echocardiography : results of a survey of echocardiographic measurements. Circulation 58 : 1072, 1978
23) Hoshi H, Kubota I, Ikeda K, Tsuiki K, Yasui S : Determination of the hypertrophic site of the left ventricle by body surface mapping in patients with hypertension. Jpn Heart J 28 829, 1987
19) Durrer D, van Dam RT, Freud GE, Janse MJ, Meijler FL, Arzbaecher RC : Total excitation of the isolated human heart. Circulation 58 398, 1978
References_xml – reference: 21) Cohen A, Hagan AD, Watkins J, Mitas J, Schvartzman M, Mazzoreni A, Cohen IM, Warren SE, Viebeg WV : Clinical correlates in hypertensive patients with left ventricular hypertrophy diagnosed with echocardiography. Am J Cardiol 47 : 335, 1981
– reference: 17) Horan LG, Flowers NC, Brody DA : Body surface potential distribution : Comparison of naturally and artificially produced signals as analyzed by digital computer. Cir Res 13 373, 1963
– reference: 23) Hoshi H, Kubota I, Ikeda K, Tsuiki K, Yasui S : Determination of the hypertrophic site of the left ventricle by body surface mapping in patients with hypertension. Jpn Heart J 28 829, 1987
– reference: 22) Safer ME, Lehner JP, Vincent MI, Plainfosse MT, Simon ACh : Echocardiographic dimensions in borderline and sustained hypertension. Am J Cardiol 44 : 930, 1979
– reference: 10) Ikeda K, Kubota I, Tonooka I, Tsuiki K, Yasui S : Detection of posterior myocardial infarction by body surface mapping : A comparative study with 12 lead ECG and VCG. J Electrocardiol 18: 361, 1985
– reference: 7) 林博史, 石川富久, 上松治儀, 小島春紀, 稲垣晴夫, 河合直樹, 外畑巌: 心尖部肥大型心筋症の体表面電位分布の特徴と定量的評価. 日内会誌71: 647, 1982
– reference: 2) Estes EH, Whalen RE, Reberts SR, Mckintosh HD: The electrocardiographic findings in idiopathic hypertrophic subaortic stenosis. Am Heart J 65 : 155, 1963
– reference: 3) Horrister RM, Goodwin JF : The electrocardiogram in cardiomyopathy. Br Heart J 25: 357, 1963
– reference: 19) Durrer D, van Dam RT, Freud GE, Janse MJ, Meijler FL, Arzbaecher RC : Total excitation of the isolated human heart. Circulation 58 398, 1978
– reference: 6) 石川富久, 林博史, 上松治儀, 小島春紀, 外畑厳, 安井昭二: 体表面電位図による中隔肥大の定性的および定量的評価. 呼と循29: 545, 1981
– reference: 1) Toshima H, Koga Y, Kimura N : Correlations between electrocardiographic, ventricurographic and echocardiographic findings in patients with left ventricular overload. Am Heart j 79 : 547, 1977
– reference: 13) Ikeda K, Kubota I, Igarashi A, Yamaki M, Tsuiki K, Yasui S : Detection of abnormalities in ventricular activation sequence by body surface isochrone mapping in patients with previous myocardial infarction. Circulation 72 : 801, 1985
– reference: 12) Montague TJ, Smith ER, Cameron DA, Rautaharju PM, Klassen GA, Fehnington GS, Horacek BM : Isointegral analysis of body surface maps : surface distribution and temporal variability in normal subjects. Circulation 63 1166, 1981
– reference: 4) Frank S, Braunwald E : Idiopathic hypertrophic sobaortic stenosis. Clinical analysis of 126 patients with emphasis on the natural history. Circulation 37 : 759, 1968
– reference: 11) Tonooka I, Kubota I, Watanabe Y, Tsuiki K, Yasui S : Isointegral analysis of body surface maps for the assessment of location and size of myocardial infarction. Am J Cardiol 52 1174, 1983
– reference: 16) Sahn DJ, DeMaria A, Kisslo J, Weyman A : Committee on M-mode Standarization of the American Society of Echocardiography : Recommendations regarding quantification in M-mode echocardiography : results of a survey of echocardiographic measurements. Circulation 58 : 1072, 1978
– reference: 5) Savage DD, Seides SF, Clark CE, Henry WL, Maron BJ, Robinson FC, Epstein SE : Electrocardiographic findings in patients with obstructive and nonobstructive hypertrophic cardiomyopathy. Circulation 54 : 402, 1978
– reference: 20) Scher AM, Young AC, Malgren AL, Erickson RV : Activation of the inter ventricular septum. Cir Res 3 : 56, 1955
– reference: 15) Watanabe T, Toyama J, Toyoshima H, Oguri H, Ohno M, Ohta T, Okajima M, Naito Y, Yamada K : A practical microcomputer based mapping system for body surface, precordium, and epicardium. Comput Biomed Res 14 341, 1981
– reference: 18) Abildskov JA, Burgess MJ, Lux RL, Wyatt RF : Experimental evidence for regional cardiac influence in body surface isopotential maps of dogs. Cir Res 38 : 386, 1976
– reference: 14) Okajima M, Doniwa K, Ishikawa T, Niimi N, Koike Y : On body surface VAT isochrone maps generated by computer using simulated excitation sequences in ventricular model. Proceedings of Computers in Cardiology, October 1980, Williamsburg, VA, 1981, 187
– reference: 8) Yoshida H, Imataki K, Nagahana H, Ihoriya F, Nakao Y, Saito D, Haraoka S : Cardiac hypertrophic cardiomyopathy and hypertension evaluated by echocardiography and body surface isopotential mapping. J Cardiography 16 : 399, 1986
– reference: 9) Flowers NC, Horan LG, Johnson JC : Anterior infarctional changes occurring during mid and late ventricular activation detectable by surface mapping techniques. Circulation 54 906, 1976
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Snippet 肥大型心筋症患者における心電図変化の特徴を正常群との隔たりを表現するdeparture mapを作成して検討した.対象は心エコー図にて中隔厚13mmをこえる肥大型心筋症患者24...
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SubjectTerms 体表面電位図
肥大型心筋症
Title 非閉塞性肥大型心筋症の体表面電位図所見
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