大腸癌におけるp53, c-erb B-2の発現とapoptosisとの関連についての検討
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| Published in | Journal of Nippon Medical School Vol. 66; no. 3; pp. 181 - 187 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
日本医科大学医学会
1999
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| Online Access | Get full text |
| ISSN | 1345-4676 1347-3409 |
| DOI | 10.1272/jnms.66.181 |
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| Author | 浅野, 伍朗 何, 群 田中, 宣威 大秋, 美治 |
|---|---|
| Author_xml | – sequence: 1 fullname: 田中, 宣威 organization: 日本医科大学千葉北総病院病理部 – sequence: 1 fullname: 何, 群 organization: 日本医科大学千葉北総病院病理部 – sequence: 1 fullname: 大秋, 美治 organization: 日本医科大学千葉北総病院病理部 – sequence: 1 fullname: 浅野, 伍朗 organization: 日本医科大学千葉北総病院病理部 |
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| Copyright | 1999 日本医科大学医学会 |
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| References | 19) McCann AH, Dervan PA, O'Regan M, Codd MB, Gullick WJ, Tobin BM, Carney DN: Prognostic significance of c-erb B-2 and estrogen receptor status in human breast cancer. Cancer Res 1991; 51: 3296-3303. 21) Lanza G Jr, Maestri I, Dubini A, Gafa R, Santini A, Ferretti S, Cavazzini L: p 53 expression in colorectal cancer: Relation to tumor type, DNA ploidy pattern and short-term survival. Am J Clin Pathol 1996; 5: 604-612. 10) Tamura T, Aoyama N, Saya H, Haga H, Futami S, Miyamoto M, Koh T, Ariyasu T, Tachi M, Kasuga M, Takahashi R: Induction of Fas-mediated apoptosis in p 53-transfected human colon carcinoma cells. Oncogene 1995; 11: 1939-1946. 2) Kerr JF, Wyllie AH, Currie AR: Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26: 239-257. 24) 山村卓也，小笹貴夫，松崎弘明，松岡博光，田中一行，及川 博，明石 治，月川 賢，山口 晋：大腸癌におけるp 53蛋白発現の臨床病理学的意義．日本大腸肛門病会誌 1998; 51: 201-208. 14) Payne CM, Bernstein H, Bernstein C, Garewal H: Role of apoptosis in biology and pathology: Resistance to apoptosis in colon carcinogenesis. Ultrastruc Pathol 1995; 19: 221-248. 9) Tomita Y, Bilim V, Kawasaki T, Takahashi K, Okan I, Magnusson KP, Wiman KG: Frequent expression of Bcl-2 in renal-cell carcinoma carrying wild-type p 53. Internat J Cancer 1996; 66: 322-325. 11) Ohashi M, Sugikawa E, Nakanishi N: Inhibition of p53 protein phosphorylation by 9-hydroxyellipticine: A possible anticancer mechanism. Jpn J Cancer Res 1995; 86: 819-827. 16) Gavrieli Y, Sherman Y, Ben-Sasson SA: Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992; 119: 493-501. 17) Mori S, Akiyama T, Yamada Y, Morishita Y, Sugawara I, Toyoshima K, Yamamoto T: c-erb B-2 gene product, a membrane protein commonly expressed on human fetal epithelial cells. Lab Invest 1989; 61: 93-97. 8) Kobayashi M, Watanabe H, Ajioka Y, Yoshica M, Hitomi J, Asakura H: Correlation of p 53 protein expression with apoptotic incidence in colorectal neoplasia. Virchows Archiv 1995; 427: 27-32. 1) Ieda S, Watatani M, Yoshida T, Kuroda K, Inui H, Yasutomi M: Immunohistochemical analysis of p 53 and ras p 21 expression in colorectal adenomas and early carcinomas. Surg Today (Jpn J Surg) 1996; 26: 230-235. 4) Sumitani K, Kamijo R, Nagumo M: Cytotoxic effect of sodium nitroprusside on cancer cells: Involvement of apoptosis and suppression of c-myc and c-myb proto-oncogene expression. Anticancer Res 1997; 17: 865-871. 20) Glinsky GV, Glinsky VV: Apoptosis and metastasis: A superior resistance of metastatic cancer cells to programmed cell death. Cancer Letters 1996; 101: 43-51. 18) Mori S, Akiyama T, Morishita Y, Shimizu S, Sakai K, Sudoh K, Toyoshima K, Yamamoto T: Light and electron microscopical demonstration of c-erb B-2 gene product-like immunoreactivity in human malignant tumors. Virchows Archiv B Cell Pathol Mol Pathol 1987; 54: 8-15. 5) Ho YS, Wang YJ, Lin JK: Induction of p 53 and p 21/WAF 1/CIP 1 expression by nitric oxide and their association with apoptosis in human cancer cells. Mol Carcinogenesis 1996; 16: 20-31. 6) Berke G: PELs and the perforin and granzyme independent mechanism of CTL-mediated lysis. Immunolog Rev 1995; 146: 21-31. 12) Polyak K, Waldman T, He TC, Kinzler KW, Vogelstein B: Genetic determinants of p 53-induced apoptosis and growth arrest. Genes and Development 1996; 10: 1945-1952. 13) 太田成男：アポトーシスと関連疾患．日医大誌 1997; 64: 73-76. 22) Houbiers JG, van der Burg SH, van de Watering LM, Tollenaar RA, Brand A, van de Velde CJ, Melief CJ: Antibodies against p 53 are associated with poor prognosis of colorectal cancer. Brit J Cancer 1995; 72: 637-641. 23) Sirvent JJ, Salvado MT, Santafe M, Martinez S, Brunet J, Alvaro T, Palacios J: p 53 in breast cancer. Its relation to histological grade, lymph-node status, hormone receptors, cell-proliferation fraction (Ki-67) and c-erb B-2 Immunohistochemical study of 153 cases. Histol Histopathol 1995; 10: 531-539. 25) Morrin M, Kelly M, Barrett N, Delaney P: Mutations of Ki-ras and p 53 genes in colorectal cancer and their prognostic significance. Gut 1994; 35: 1627-1631. 3) Cummings MC, Winterford CM, Walker NI: Apoptosis. Am J Surg Pathol 1997; 21: 88-101. 15) 赤木忠厚，芳野 正，近藤英作：アポトーシスシグナルの受容体とリガンド（Fasを中心として）：特に免疫系における役割．病理と臨床 1998; 16: 1494-1499. 7) Berke G: Killing mechanisms of cytotoxic lymphocytes. Current Opinion in Hematol 1997; 4: 32-40. |
| References_xml | – reference: 19) McCann AH, Dervan PA, O'Regan M, Codd MB, Gullick WJ, Tobin BM, Carney DN: Prognostic significance of c-erb B-2 and estrogen receptor status in human breast cancer. Cancer Res 1991; 51: 3296-3303. – reference: 5) Ho YS, Wang YJ, Lin JK: Induction of p 53 and p 21/WAF 1/CIP 1 expression by nitric oxide and their association with apoptosis in human cancer cells. Mol Carcinogenesis 1996; 16: 20-31. – reference: 18) Mori S, Akiyama T, Morishita Y, Shimizu S, Sakai K, Sudoh K, Toyoshima K, Yamamoto T: Light and electron microscopical demonstration of c-erb B-2 gene product-like immunoreactivity in human malignant tumors. Virchows Archiv B Cell Pathol Mol Pathol 1987; 54: 8-15. – reference: 9) Tomita Y, Bilim V, Kawasaki T, Takahashi K, Okan I, Magnusson KP, Wiman KG: Frequent expression of Bcl-2 in renal-cell carcinoma carrying wild-type p 53. Internat J Cancer 1996; 66: 322-325. – reference: 10) Tamura T, Aoyama N, Saya H, Haga H, Futami S, Miyamoto M, Koh T, Ariyasu T, Tachi M, Kasuga M, Takahashi R: Induction of Fas-mediated apoptosis in p 53-transfected human colon carcinoma cells. Oncogene 1995; 11: 1939-1946. – reference: 22) Houbiers JG, van der Burg SH, van de Watering LM, Tollenaar RA, Brand A, van de Velde CJ, Melief CJ: Antibodies against p 53 are associated with poor prognosis of colorectal cancer. Brit J Cancer 1995; 72: 637-641. – reference: 16) Gavrieli Y, Sherman Y, Ben-Sasson SA: Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992; 119: 493-501. – reference: 14) Payne CM, Bernstein H, Bernstein C, Garewal H: Role of apoptosis in biology and pathology: Resistance to apoptosis in colon carcinogenesis. Ultrastruc Pathol 1995; 19: 221-248. – reference: 2) Kerr JF, Wyllie AH, Currie AR: Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26: 239-257. – reference: 6) Berke G: PELs and the perforin and granzyme independent mechanism of CTL-mediated lysis. Immunolog Rev 1995; 146: 21-31. – reference: 1) Ieda S, Watatani M, Yoshida T, Kuroda K, Inui H, Yasutomi M: Immunohistochemical analysis of p 53 and ras p 21 expression in colorectal adenomas and early carcinomas. Surg Today (Jpn J Surg) 1996; 26: 230-235. – reference: 8) Kobayashi M, Watanabe H, Ajioka Y, Yoshica M, Hitomi J, Asakura H: Correlation of p 53 protein expression with apoptotic incidence in colorectal neoplasia. Virchows Archiv 1995; 427: 27-32. – reference: 15) 赤木忠厚，芳野 正，近藤英作：アポトーシスシグナルの受容体とリガンド（Fasを中心として）：特に免疫系における役割．病理と臨床 1998; 16: 1494-1499. – reference: 13) 太田成男：アポトーシスと関連疾患．日医大誌 1997; 64: 73-76. – reference: 11) Ohashi M, Sugikawa E, Nakanishi N: Inhibition of p53 protein phosphorylation by 9-hydroxyellipticine: A possible anticancer mechanism. Jpn J Cancer Res 1995; 86: 819-827. – reference: 21) Lanza G Jr, Maestri I, Dubini A, Gafa R, Santini A, Ferretti S, Cavazzini L: p 53 expression in colorectal cancer: Relation to tumor type, DNA ploidy pattern and short-term survival. Am J Clin Pathol 1996; 5: 604-612. – reference: 3) Cummings MC, Winterford CM, Walker NI: Apoptosis. Am J Surg Pathol 1997; 21: 88-101. – reference: 4) Sumitani K, Kamijo R, Nagumo M: Cytotoxic effect of sodium nitroprusside on cancer cells: Involvement of apoptosis and suppression of c-myc and c-myb proto-oncogene expression. Anticancer Res 1997; 17: 865-871. – reference: 12) Polyak K, Waldman T, He TC, Kinzler KW, Vogelstein B: Genetic determinants of p 53-induced apoptosis and growth arrest. Genes and Development 1996; 10: 1945-1952. – reference: 17) Mori S, Akiyama T, Yamada Y, Morishita Y, Sugawara I, Toyoshima K, Yamamoto T: c-erb B-2 gene product, a membrane protein commonly expressed on human fetal epithelial cells. Lab Invest 1989; 61: 93-97. – reference: 25) Morrin M, Kelly M, Barrett N, Delaney P: Mutations of Ki-ras and p 53 genes in colorectal cancer and their prognostic significance. Gut 1994; 35: 1627-1631. – reference: 23) Sirvent JJ, Salvado MT, Santafe M, Martinez S, Brunet J, Alvaro T, Palacios J: p 53 in breast cancer. Its relation to histological grade, lymph-node status, hormone receptors, cell-proliferation fraction (Ki-67) and c-erb B-2 Immunohistochemical study of 153 cases. Histol Histopathol 1995; 10: 531-539. – reference: 7) Berke G: Killing mechanisms of cytotoxic lymphocytes. Current Opinion in Hematol 1997; 4: 32-40. – reference: 24) 山村卓也，小笹貴夫，松崎弘明，松岡博光，田中一行，及川 博，明石 治，月川 賢，山口 晋：大腸癌におけるp 53蛋白発現の臨床病理学的意義．日本大腸肛門病会誌 1998; 51: 201-208. – reference: 20) Glinsky GV, Glinsky VV: Apoptosis and metastasis: A superior resistance of metastatic cancer cells to programmed cell death. Cancer Letters 1996; 101: 43-51. |
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| Title | 大腸癌におけるp53, c-erb B-2の発現とapoptosisとの関連についての検討 |
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