OTOGENIC INTRACRANIAL COMPLICATIONS : A REVIEW OF 3 CASES

Although otogenic intracranial complications are considered to be relatively rare, they may still be potentially life-threatening. We report our experiences with 5 patients presenting with otogenic intracranial complications who were treated at the University of Tsukuba Hospital from 2002 to 2011. C...

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Published inJIBI INKOKA TEMBO Vol. 56; no. Supplement1; pp. s34 - s39
Main Authors Yoshimura, Tomonori, Nakayama, Masahiro, Ashizawa, Kei, Tanaka, Shuho, Tabuchi, Keiji, Hirose, Yuki, Nishimura, Bungo, Okubo, Hideki, Wada, Tetsuro, Nakamagoe, Mariko, Hara, Akira, Hoshino, Tomofumi, Uemaetomari, Isao
Format Journal Article
LanguageJapanese
Published Society of Oto-rhino-laryngology Tokyo 05.03.2013
耳鼻咽喉科展望会
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ISSN0386-9687
1883-6429
DOI10.11453/orltokyo.56.s34

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Abstract Although otogenic intracranial complications are considered to be relatively rare, they may still be potentially life-threatening. We report our experiences with 5 patients presenting with otogenic intracranial complications who were treated at the University of Tsukuba Hospital from 2002 to 2011. Case 1 was a 7-year-old girl who presented with fever, otalgia, and headache, who had been diagnosed as having acute otitis media at another hospital. Magnetic resonance imaging (MRI) demonstrated mastoiditis with sigmoid sinus thrombophlebitis. The child was successfully treated by intravenous antibiotic therapy. Case 2 was a male in his 60's who presented with the complaints of dizziness and vomiting. MRI showed an epidural abscess in the posterior cranial fossa caused by otitis media with a cholesteatoma. Abscess drainage, tympanoplasty and mastoidectomy were performed. Case 3 was a female patient in her 40's with inner ear anomalies associated with recurrent meningitis. During surgical treatment, cerebrospinal fluid leakage through a bony defect in the stapedial footplate was observed. After removal of the stapes, intralabyrinthine obliteration was performed and the oval window was sealed. The two remaining patients were two children with meningitis complicating otitis media with a cholesteatoma. Both cases were successfully treated by surgery. A clinical suspicion of otogenic intracranial complications would seem to be essential to make an accurate diagnosis during the early stage of the disease and achieve successful outcomes.
AbstractList Although otogenic intracranial complications are considered to be relatively rare, they may still be potentially life-threatening. We report our experiences with 5 patients presenting with otogenic intracranial complications who were treated at the University of Tsukuba Hospital from 2002 to 2011. Case 1 was a 7-year-old girl who presented with fever, otalgia, and headache, who had been diagnosed as having acute otitis media at another hospital. Magnetic resonance imaging (MRI) demonstrated mastoiditis with sigmoid sinus thrombophlebitis. The child was successfully treated by intravenous antibiotic therapy. Case 2 was a male in his 60's who presented with the complaints of dizziness and vomiting. MRI showed an epidural abscess in the posterior cranial fossa caused by otitis media with a cholesteatoma. Abscess drainage, tympanoplasty and mastoidectomy were performed. Case 3 was a female patient in her 40's with inner ear anomalies associated with recurrent meningitis. During surgical treatment, cerebrospinal fluid leakage through a bony defect in the stapedial footplate was observed. After removal of the stapes, intralabyrinthine obliteration was performed and the oval window was sealed. The two remaining patients were two children with meningitis complicating otitis media with a cholesteatoma. Both cases were successfully treated by surgery. A clinical suspicion of otogenic intracranial complications would seem to be essential to make an accurate diagnosis during the early stage of the disease and achieve successful outcomes.
Although otogenic intracranial complications are considered to be relatively rare, they may still be potentially life-threatening. We report our experiences with 5 patients presenting with otogenic intracranial complications who were treated at the University of Tsukuba Hospital from 2002 to 2011. Case 1 was a 7-year-old girl who presented with fever, otalgia, and headache, who had been diagnosed as having acute otitis media at another hospital. Magnetic resonance imaging (MRI) demonstrated mastoiditis with sigmoid sinus thrombophlebitis. The child was successfully treated by intravenous antibiotic therapy. Case 2 was a male in his 60's who presented with the complaints of dizziness and vomiting. MRI showed an epidural abscess in the posterior cranial fossa caused by otitis media with a cholesteatoma. Abscess drainage, tympanoplasty and mastoidectomy were performed. Case 3 was a female patient in her 40's with inner ear anomalies associated with recurrent meningitis. During surgical treatment, cerebrospinal fluid leakage through a bony defect in the stapedial footplate was observed. After removal of the stapes, intralabyrinthine obliteration was performed and the oval window was sealed. The two remaining patients were two children with meningitis complicating otitis media with a cholesteatoma. Both cases were successfully treated by surgery.A clinical suspicion of otogenic intracranial complications would seem to be essential to make an accurate diagnosis during the early stage of the disease and achieve successful outcomes. 耳疾患が原因となって頭蓋内に炎症が波及する耳性頭蓋内合併症は, 抗生物質が発達した今日においてもその症状はきわめて重篤であり見逃してはいけない疾患である。今回, 我々は2002年1月から2011年12月までの10年間において耳性頭蓋内合併症を5症例 (S状静脈洞血栓症1例, 硬膜外膿瘍1例, 髄膜炎3例) 経験した。乳様突起炎に伴うS状静脈洞血栓症 (7歳, 女児) は抗菌薬による保存的加療で改善した。慢性中耳炎より発症した硬膜外膿瘍症例 (60歳代, 男性) は脳外科的手術, 耳科手術を行った。細菌性髄膜炎を反復した先天性内耳奇形症例 (40歳代, 女性) は手術により, 中耳-内耳の異常交通を遮断し, 以降, 髄膜炎は再発していない。また, 他2例は真珠腫性中耳炎から波及した細菌性髄膜炎であったが, 耳科手術を行った。耳性頭蓋内合併症の頻度は必ずしも高くはないが, その存在を常に念頭におき, 日々の診療を行う必要があると考えた。
Author Nakayama, Masahiro
Wada, Tetsuro
Nakamagoe, Mariko
Ashizawa, Kei
Tabuchi, Keiji
Yoshimura, Tomonori
Nishimura, Bungo
Hoshino, Tomofumi
Uemaetomari, Isao
Okubo, Hideki
Hara, Akira
Hirose, Yuki
Tanaka, Shuho
Author_FL 和田 哲郎
吉村 知倫
田中 秀峰
中山 雅博
廣瀬 由紀
芦澤 圭
西村 文吾
中馬越 真理子
原 晃
大久保 英樹
田渕 経司
星野 朝文
上前泊 功
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  fullname: Uemaetomari, Isao
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耳鼻咽喉科展望会
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References 2) 安田 京, 黒田令子, 橋本敏光, 佐々木亮, 新川秀一: 耳性頭蓋内合併症例. 耳鼻臨床 95: 1025-1029, 2002.
4) 水越彬文, 平海晴一, 山本典夫, 坂本達則, 伊藤壽一: S状静脈洞血栓症を伴った乳様突起炎例. 耳鼻臨床 104: 415-418, 2011.
1) 田渕経司, 辻 茂希, 飛田忠道, 高橋和彦, 大久保英樹, 他: 当科における耳性頭蓋内合併症症例. Otol Jpn 14: 66-69, 2004.
6) Kaplan DM, Kraus M, Puterman M, Niv A, Leiberman A, et al: Otogenic lateral sinus thrombosis in children. Int J Pediatr Otorhinolaryngol 49: 177-183, 1999.
12) 水野正浩: 耳性頭蓋内合併症. JOHNS 15: 410-414, 1999.
10) 吉田泰行, 新川 敦, 木村栄成, 橘田 豊, 坂井 真: 中耳真珠腫による脳膿瘍例 ―脳外科的処置をめぐって―. 耳鼻臨床 85: 1383-1390, 1992.
8) Urwald O, Merol JC, Legros M: Acute mastoiditis in children: a series of 38 cases. Ann Otolaryngol Chir Cervicofac 119: 264-270, 2002.
14) 上條 篤, 野沢 出, 久松健一, 荻野 純, 中沢真理, 他: 耳性小脳膿瘍の1症例と最近の耳性頭蓋内合併症について. 耳鼻臨床 補79: 28-36, 1995.
15) Jackler RK, Luxford WM, House WF: Congenital malformations of the inner ear: a classification based on embryogenesis. Laryngoscope 97: 2-14, 1987.
16) 青木光広, 水田啓介, 安藤健一, 山田南星, 伊藤八次, 他: 耳性髄液漏を伴った髄膜炎を発症した内耳奇形合併成人例. 耳鼻臨床 102: 99-102, 2009.
3) Vazquez E, Castellote A, Piqueras J, Mauleon S, Creixell S, et al: Imaging of complications of acute mastoiditis in children. Radiographics 23: 359-372, 2003.
11) 大迫廣人, 山崎正幸, 下薗政巳, 東野哲也: 耳性頭蓋内合併症の2例. 耳鼻 42: 874-879, 1996.
13) 石田正人, 星野知之, 野末道彦: 耳性脳膿瘍の3症例. 耳喉 58: 227-231, 1986.
9) Shah UK, Jubelirer TF, Fish JD, Elden LM: A caution regarding the use of low-molecular weight heparin in pediatric otogenic lateral sinus thrombosis. Int J Pediatr Otorhinolaryngol 71: 347-351, 2007.
5) Kangsanarak J, Navacharoen N, Fooanant S, Ruckphaopunt K: Intracranial complications of suppurative otitis media: 13 years' experience. Am J Otol 16: 104-109, 1999.
7) Nakayama M, Tabuchi K, Nomura M, Murashita H, Komeno M, et al: Thrombophlebitis of the head and neck: report of two cases. Auris Nasus Larynx 37: 651-655, 2010.
References_xml – reference: 1) 田渕経司, 辻 茂希, 飛田忠道, 高橋和彦, 大久保英樹, 他: 当科における耳性頭蓋内合併症症例. Otol Jpn 14: 66-69, 2004.
– reference: 5) Kangsanarak J, Navacharoen N, Fooanant S, Ruckphaopunt K: Intracranial complications of suppurative otitis media: 13 years' experience. Am J Otol 16: 104-109, 1999.
– reference: 7) Nakayama M, Tabuchi K, Nomura M, Murashita H, Komeno M, et al: Thrombophlebitis of the head and neck: report of two cases. Auris Nasus Larynx 37: 651-655, 2010.
– reference: 12) 水野正浩: 耳性頭蓋内合併症. JOHNS 15: 410-414, 1999.
– reference: 9) Shah UK, Jubelirer TF, Fish JD, Elden LM: A caution regarding the use of low-molecular weight heparin in pediatric otogenic lateral sinus thrombosis. Int J Pediatr Otorhinolaryngol 71: 347-351, 2007.
– reference: 4) 水越彬文, 平海晴一, 山本典夫, 坂本達則, 伊藤壽一: S状静脈洞血栓症を伴った乳様突起炎例. 耳鼻臨床 104: 415-418, 2011.
– reference: 2) 安田 京, 黒田令子, 橋本敏光, 佐々木亮, 新川秀一: 耳性頭蓋内合併症例. 耳鼻臨床 95: 1025-1029, 2002.
– reference: 8) Urwald O, Merol JC, Legros M: Acute mastoiditis in children: a series of 38 cases. Ann Otolaryngol Chir Cervicofac 119: 264-270, 2002.
– reference: 15) Jackler RK, Luxford WM, House WF: Congenital malformations of the inner ear: a classification based on embryogenesis. Laryngoscope 97: 2-14, 1987.
– reference: 16) 青木光広, 水田啓介, 安藤健一, 山田南星, 伊藤八次, 他: 耳性髄液漏を伴った髄膜炎を発症した内耳奇形合併成人例. 耳鼻臨床 102: 99-102, 2009.
– reference: 6) Kaplan DM, Kraus M, Puterman M, Niv A, Leiberman A, et al: Otogenic lateral sinus thrombosis in children. Int J Pediatr Otorhinolaryngol 49: 177-183, 1999.
– reference: 14) 上條 篤, 野沢 出, 久松健一, 荻野 純, 中沢真理, 他: 耳性小脳膿瘍の1症例と最近の耳性頭蓋内合併症について. 耳鼻臨床 補79: 28-36, 1995.
– reference: 3) Vazquez E, Castellote A, Piqueras J, Mauleon S, Creixell S, et al: Imaging of complications of acute mastoiditis in children. Radiographics 23: 359-372, 2003.
– reference: 10) 吉田泰行, 新川 敦, 木村栄成, 橘田 豊, 坂井 真: 中耳真珠腫による脳膿瘍例 ―脳外科的処置をめぐって―. 耳鼻臨床 85: 1383-1390, 1992.
– reference: 11) 大迫廣人, 山崎正幸, 下薗政巳, 東野哲也: 耳性頭蓋内合併症の2例. 耳鼻 42: 874-879, 1996.
– reference: 13) 石田正人, 星野知之, 野末道彦: 耳性脳膿瘍の3症例. 耳喉 58: 227-231, 1986.
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Snippet Although otogenic intracranial complications are considered to be relatively rare, they may still be potentially life-threatening. We report our experiences...
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SubjectTerms epidural abscess
inner ear anomaly
mengitis
otogenic intracranial complication
sigmoid sinus thrombophlebitis
S状静脈洞血栓症
内耳奇形
硬膜外膿瘍
耳性頭蓋内合併症
髄膜炎
Title OTOGENIC INTRACRANIAL COMPLICATIONS : A REVIEW OF 3 CASES
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