A STUDY OF ASTHMA DEATHS IN A THIRD-LEVEL EMERGENCY CENTER

In recent years, mortality from bronchial asthma has increased in industrialized countries. The annual number of deaths from asthma in Japan is about 6, 000, which is somewhat higher than in other industrialized countries in Europe and North America. We, therefore, studied the causes of and the coun...

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Published inJournal of The Showa Medical Association Vol. 58; no. 3; pp. 270 - 276
Main Authors OSAKABE, Yoshimi, TAKAHASHI, Yoshiki, SUZUKI, Hajime
Format Journal Article
LanguageEnglish
Japanese
Published The Showa University Society 1998
昭和大学学士会
Subjects
Online AccessGet full text
ISSN0037-4342
2185-0976
DOI10.14930/jsma1939.58.270

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Abstract In recent years, mortality from bronchial asthma has increased in industrialized countries. The annual number of deaths from asthma in Japan is about 6, 000, which is somewhat higher than in other industrialized countries in Europe and North America. We, therefore, studied the causes of and the countermeasures against asthma deaths from the point of view of a third-level emergency. The subjects were patients with bronchial asthma who required eudotracheal intubation. Subjects were selected for this study from among patients who had been brought by ambulance to the emergency center of our hospital, which is a third-level emergency facility. The subjects were 92 patients with asthma who were hospitalized at our center during the 12 years from April 1985 through March 1997. Sixty-one patients required eudotracheal intubation (34 males and 27 females ; average age, 41.7±20.9) . Divided by type of asthma, 34 patients (55.7 % ) with an average age of 30.5±17.5 years had atopic (type A ) asthma and 27 patients (44.3 %) with an average age of 56.2±17.0 years had nonatopic (type NA) asthma. After receiving emergency care 30 patients (50.8 %) survived and 31 patients (49.2 %) died. Of the patients who died, 25 (80.6 %) had cardiopulmonary arrest on arrival. Deaths were particularly common among young patients with type A asthma. We examined the respiratory index (RI) to evaluate the severity of disease when patients were hospitalized. Patients who died had a poor RI. We then examined the time required for patients to be brought to the hospital (by ambulance only) ; we found that the time of transport had no effect on outcome. Thus, we concluded that the problems must have arisen before the patients were transported by ambulance. A survey of clinics and the patients' attitudes toward treatment showed that 78 % of patients who died had been treated by physicians and that 78 % had received treatment irregularly and at the time of asthmatic attacks. It was found that among patients who had been brought to third-level emergency facilities, young patients with type A asthma were more likely to die of asthma and had visited physicians on an irregular basis. Our retrospective study suggests that these physicians lacked sufficient knowledge of allergic diseases and failed to properly educate their patients about asthma and provide the most appropriate treatment during asthma attacks. We believe that deaths from asthma could be decreased by educating clinical physicians who treat asthma patients.
AbstractList In recent years, mortality from bronchial asthma has increased in industrialized countries. The annual number of deaths from asthma in Japan is about 6, 000, which is somewhat higher than in other industrialized countries in Europe and North America. We, therefore, studied the causes of and the countermeasures against asthma deaths from the point of view of a third-level emergency. The subjects were patients with bronchial asthma who required eudotracheal intubation. Subjects were selected for this study from among patients who had been brought by ambulance to the emergency center of our hospital, which is a third-level emergency facility. The subjects were 92 patients with asthma who were hospitalized at our center during the 12 years from April 1985 through March 1997. Sixty-one patients required eudotracheal intubation (34 males and 27 females ; average age, 41.7±20.9) . Divided by type of asthma, 34 patients (55.7 % ) with an average age of 30.5±17.5 years had atopic (type A ) asthma and 27 patients (44.3 %) with an average age of 56.2±17.0 years had nonatopic (type NA) asthma. After receiving emergency care 30 patients (50.8 %) survived and 31 patients (49.2 %) died. Of the patients who died, 25 (80.6 %) had cardiopulmonary arrest on arrival. Deaths were particularly common among young patients with type A asthma. We examined the respiratory index (RI) to evaluate the severity of disease when patients were hospitalized. Patients who died had a poor RI. We then examined the time required for patients to be brought to the hospital (by ambulance only) ; we found that the time of transport had no effect on outcome. Thus, we concluded that the problems must have arisen before the patients were transported by ambulance. A survey of clinics and the patients' attitudes toward treatment showed that 78 % of patients who died had been treated by physicians and that 78 % had received treatment irregularly and at the time of asthmatic attacks. It was found that among patients who had been brought to third-level emergency facilities, young patients with type A asthma were more likely to die of asthma and had visited physicians on an irregular basis. Our retrospective study suggests that these physicians lacked sufficient knowledge of allergic diseases and failed to properly educate their patients about asthma and provide the most appropriate treatment during asthma attacks. We believe that deaths from asthma could be decreased by educating clinical physicians who treat asthma patients.
In recent years, mortality from bronchial asthma has increased in industrialized countries. The annual number of deaths from asthma in Japan is about 6, 000, which is somewhat higher than in other industrialized countries in Europe and North America. We, therefore, studied the causes of and the countermeasures against asthma deaths from the point of view of a third-level emergency. The subjects were patients with bronchial asthma who required eudotracheal intubation. Subjects were selected for this study from among patients who had been brought by ambulance to the emergency center of our hospital, which is a third-level emergency facility. The subjects were 92 patients with asthma who were hospitalized at our center during the 12 years from April 1985 through March 1997. Sixty-one patients required eudotracheal intubation (34 males and 27 females ; average age, 41.7±20.9) . Divided by type of asthma, 34 patients (55.7 % ) with an average age of 30.5±17.5 years had atopic (type A ) asthma and 27 patients (44.3 %) with an average age of 56.2±17.0 years had nonatopic (type NA) asthma. After receiving emergency care 30 patients (50.8 %) survived and 31 patients (49.2 %) died. Of the patients who died, 25 (80.6 %) had cardiopulmonary arrest on arrival. Deaths were particularly common among young patients with type A asthma. We examined the respiratory index (RI) to evaluate the severity of disease when patients were hospitalized. Patients who died had a poor RI. We then examined the time required for patients to be brought to the hospital (by ambulance only) ; we found that the time of transport had no effect on outcome. Thus, we concluded that the problems must have arisen before the patients were transported by ambulance. A survey of clinics and the patients' attitudes toward treatment showed that 78 % of patients who died had been treated by physicians and that 78 % had received treatment irregularly and at the time of asthmatic attacks. It was found that among patients who had been brought to third-level emergency facilities, young patients with type A asthma were more likely to die of asthma and had visited physicians on an irregular basis. Our retrospective study suggests that these physicians lacked sufficient knowledge of allergic diseases and failed to properly educate their patients about asthma and provide the most appropriate treatment during asthma attacks. We believe that deaths from asthma could be decreased by educating clinical physicians who treat asthma patients. 近年, 先進諸国における気管支喘息の死亡率は増加傾向にある.特に本邦の喘息死の年間死亡数は約6, 000人前後と同じ先進国である欧米などに比べて極めて高い.このため, 我国では喘息死の原因や対策に関する報告が数多く発表されているが, しかし重篤な発作を対象とした三次救急施設からの喘息死に関する報告は少ない.今回, 三次救急施設である本院救命センターに気管支喘息で搬送された症例のうち, 気管内挿管を必要とした重症喘息を対象に三次救急的見地から喘息死の原因および対策についての検討を行った.対象は1985年4月~97年3月までの12年間に当センターに入院した喘息患者92例中, 気管内挿管を行った61症例 (男34例, 女27例で平均年齢は41.7歳) である.これらの患者をSwinefordの分類に準じて病型分類を行ったところ, アトピー型 (A型) が34例 (55.7%) , 平均年齢は30.5歳, 非アトピー型 (NA型) は27例 (44.3%) , 平均年齢は56.2歳であった.転帰は生存例が30例 (50.8%) , 死亡例は31例 (49.2%) であった.また死亡例にはcardio pulmonary arest on arival (CPAOA, 来院時心肺停止) が25例 (80.6%) 含まれていた.死亡例の病型別分類では半数以上がA型の若年齢者であった.入院時の重症度評価をRespiratory Index (RI) により検討したところ, 死亡例で著しく悪かったため, 早期搬送の重要性を考慮して搬送時間 (救急車利用のみ) を検討したところ, 生存, 死亡の両例に有意な差はなかった.これより, 喘息死の原因をセンター搬送以前の問題と考え, 診療施設および診療態度の検討を行った.結果は死亡例の78%が開業医受診例で, さらに, 発作時だけあるいは不定期な受診例が75%もあった.今回の検討から我々は医師のアレルギー疾患に対する知識, 認識不足が喘息教育や的確な治療を患者や家族へおこなわれていなかったことをretrospective studyから示唆した.三次救急的見地から喘息死を減少させる対策として, 医師の喘息教育の向上とそれによって患者を定期受診させることが必要であると思われた.
Author TAKAHASHI, Yoshiki
OSAKABE, Yoshimi
SUZUKI, Hajime
Author_FL 刑部 義美
鈴木 一
高橋 愛樹
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  organization: Department of Pulmonary medicine Showa University, Fujigaoka Hospital
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References 7) 須藤守男, 北沢俊一: 喘息死を防ぐには. 総合臨床41: 3114-3116, 1992.
3) Paulozzi LJ, Coleman JJ and Buist AS : A recent increase in asthma mortality inthe northwestern United States. Ann All-ergy 56: 392-395, 1986.
10) 末次勧: Drug-induced asthma. 呼吸4: 604-609, 1985.
13) 刑部義美, 兼坂茂, 成原健太郎, ほか: 喘息重積発作とDOA. 日救命医療研会誌6: 5-12, 1992.
12) 江頭洋治: 成人喘息の概念. 5. 背景因子1. 厚生省科学研究費助成による成人気管支喘息実態に関する共同研究-ワークショップ記録, p. 25, 1990.
20) 宮坂雄平: 改訂救急救命士標準テキスト, 医療関連法規 (厚生省健康政策局指導監修) pp. 8-11, ヘルス出版, 東京, 1992.
19) 梅枝愛朗, 小林節雄, 伊藤秀明: 窒息死. 呼吸6: 568-574, 1987.
2) Robin ED: Death from bronchial asthma. Chest 93: 614-618, 1988.
15) 野口英世, 鈴木一, 刑部義美, ほか: 喘息の合併症と予後. 総合臨床32: 2316-2319, 1983.
16) 秋山一夫, 饗庭三代治, 柳川洋, ほか: 我国に於ける成人気管支喘息の実態. 日胸疾会誌29: 984-992, 1991.
18) 小林仁, 田村昌士: 重症気管支喘息の診断. 日本臨床45: 1814-1821, 1987.
22) 宮城征四郎, 喜屋武幸男, 小浦方啓代: 救急医療からみたハイリスクの選定と対策. アレルギー43: 272, 1994.
5) Jackson RT, Beaglehole R, Rea HH, et al : Mortality from asthma ; a new epidemic in New Zealand. Br Med J 285 : 771-774, 1982.
9) Szckeklik A, Gryglewski RJ and Czerniawska MG: Clinical patterns of hypersensitivity to nonsteroidal antiinflammato-ry drugs and their pathogenesis.) Aller-gy Clin Immunol 60: 276-284, 1977.
1) 小林節雄: 世界的観点からみた喘息死の疫学と対策. アレルギー42: 501-504, 1993.
11) 中川武正, 伊藤浩治, 奥平博一, ほか: 静岡県藤枝市に於ける成人気管支喘息の有病率調査. 日胸疾会誌25: 873-978, 1987.
17) 厚生省人口動態統計編: 厚生省の指標. 36. p. 393. 財団法人厚生統計協会. 東京, 1989.
21) 岸川禮子: 気管支喘息の生活指導. 日内会誌81: 856-860, 1992.
4) 厚生省大臣官房統計情報部編: 平成元年人口動態統計上巻. p159, 財団法人厚生統計協会, 東京. 1991.
14) 刑部義美, 鈴木一, 高橋愛樹, ほか: 救命センターに於ける喘息死の検討. 総合臨床40: 1115-1116, 1991.
8) 小林節雄, 飯倉洋治, 可部順三郎, ほか: 喘息死. 呼吸8: 1269-1283, 1989.
6) 真野健次: 喘息の急性増悪 (成人) . 集中治療6: 11-8, 1994.
References_xml – reference: 13) 刑部義美, 兼坂茂, 成原健太郎, ほか: 喘息重積発作とDOA. 日救命医療研会誌6: 5-12, 1992.
– reference: 9) Szckeklik A, Gryglewski RJ and Czerniawska MG: Clinical patterns of hypersensitivity to nonsteroidal antiinflammato-ry drugs and their pathogenesis.) Aller-gy Clin Immunol 60: 276-284, 1977.
– reference: 10) 末次勧: Drug-induced asthma. 呼吸4: 604-609, 1985.
– reference: 18) 小林仁, 田村昌士: 重症気管支喘息の診断. 日本臨床45: 1814-1821, 1987.
– reference: 19) 梅枝愛朗, 小林節雄, 伊藤秀明: 窒息死. 呼吸6: 568-574, 1987.
– reference: 1) 小林節雄: 世界的観点からみた喘息死の疫学と対策. アレルギー42: 501-504, 1993.
– reference: 16) 秋山一夫, 饗庭三代治, 柳川洋, ほか: 我国に於ける成人気管支喘息の実態. 日胸疾会誌29: 984-992, 1991.
– reference: 20) 宮坂雄平: 改訂救急救命士標準テキスト, 医療関連法規 (厚生省健康政策局指導監修) pp. 8-11, ヘルス出版, 東京, 1992.
– reference: 2) Robin ED: Death from bronchial asthma. Chest 93: 614-618, 1988.
– reference: 4) 厚生省大臣官房統計情報部編: 平成元年人口動態統計上巻. p159, 財団法人厚生統計協会, 東京. 1991.
– reference: 6) 真野健次: 喘息の急性増悪 (成人) . 集中治療6: 11-8, 1994.
– reference: 8) 小林節雄, 飯倉洋治, 可部順三郎, ほか: 喘息死. 呼吸8: 1269-1283, 1989.
– reference: 11) 中川武正, 伊藤浩治, 奥平博一, ほか: 静岡県藤枝市に於ける成人気管支喘息の有病率調査. 日胸疾会誌25: 873-978, 1987.
– reference: 15) 野口英世, 鈴木一, 刑部義美, ほか: 喘息の合併症と予後. 総合臨床32: 2316-2319, 1983.
– reference: 14) 刑部義美, 鈴木一, 高橋愛樹, ほか: 救命センターに於ける喘息死の検討. 総合臨床40: 1115-1116, 1991.
– reference: 3) Paulozzi LJ, Coleman JJ and Buist AS : A recent increase in asthma mortality inthe northwestern United States. Ann All-ergy 56: 392-395, 1986.
– reference: 7) 須藤守男, 北沢俊一: 喘息死を防ぐには. 総合臨床41: 3114-3116, 1992.
– reference: 12) 江頭洋治: 成人喘息の概念. 5. 背景因子1. 厚生省科学研究費助成による成人気管支喘息実態に関する共同研究-ワークショップ記録, p. 25, 1990.
– reference: 22) 宮城征四郎, 喜屋武幸男, 小浦方啓代: 救急医療からみたハイリスクの選定と対策. アレルギー43: 272, 1994.
– reference: 5) Jackson RT, Beaglehole R, Rea HH, et al : Mortality from asthma ; a new epidemic in New Zealand. Br Med J 285 : 771-774, 1982.
– reference: 17) 厚生省人口動態統計編: 厚生省の指標. 36. p. 393. 財団法人厚生統計協会. 東京, 1989.
– reference: 21) 岸川禮子: 気管支喘息の生活指導. 日内会誌81: 856-860, 1992.
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Snippet In recent years, mortality from bronchial asthma has increased in industrialized countries. The annual number of deaths from asthma in Japan is about 6, 000,...
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StartPage 270
SubjectTerms asthma death
atopic type asthma bronchial
education of asthma
third-level emergency center
treatment of irregulary
アトピー型喘息
三次救命救急施設
不定期治療
喘息教育
喘息死
Title A STUDY OF ASTHMA DEATHS IN A THIRD-LEVEL EMERGENCY CENTER
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