INTERFERON TREATMENT OF HEPATITIS C
Thirty percent of the patients who underwent interferon treatment showed the continuous normalization of ALT level and the continuous disappearance of HCV-RNA from serum and they were regarded as clinical cure. HCV-RNA level and HCV genotype had a connection with the prediction for IFN response. HCV...
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| Published in | Japanese Journal of National Medical Services Vol. 47; no. 10; pp. 753 - 757 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
Japanese Society of National Medical Services
1993
一般社団法人 国立医療学会 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0021-1699 1884-8729 |
| DOI | 10.11261/iryo1946.47.753 |
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| Abstract | Thirty percent of the patients who underwent interferon treatment showed the continuous normalization of ALT level and the continuous disappearance of HCV-RNA from serum and they were regarded as clinical cure. HCV-RNA level and HCV genotype had a connection with the prediction for IFN response. HCV-RNA level was a more important factor than HCV-genotype. |
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| AbstractList | Thirty percent of the patients who underwent interferon treatment showed the continuous normalization of ALT level and the continuous disappearance of HCV-RNA from serum and they were regarded as clinical cure. HCV-RNA level and HCV genotype had a connection with the prediction for IFN response. HCV-RNA level was a more important factor than HCV-genotype. Thirty percent of the patients who underwent interferon treatment showed the continuous normalization of ALT level and the continuous disappearance of HCV-RNA from serum and they were regarded as clinical cure. HCV-RNA level and HCV genotype had a connection with the prediction for IFN response. HCV-RNA level was a more important factor than HCV-genotype. IFN治療によりC型慢性肝炎患者の約30%は, 治療終了後も, 持続的なGPTの正常化とHCV-RNAの持続的消失が得られ, 臨床的にも治癒したと考えられる. 治療効果を予測する因子として, 治療前のHCV-RNA量, HCV-genotypeが関係するが, 両因子の相互関係からは, HCV-RNA量がより重要である. |
| Author | INOKUCHI, Kaoru INOUE, Osami KOGA, Michiaki YANO, Michitami MATSUMURA, Nobuyuki YATSUHASHI, Hiroshi |
| Author_FL | 猪口 薫 八橋 弘 矢野 右人 井上 長三 松村 暢之 古賀 満明 |
| Author_FL_xml | – sequence: 1 fullname: 八橋 弘 – sequence: 2 fullname: 猪口 薫 – sequence: 3 fullname: 松村 暢之 – sequence: 4 fullname: 井上 長三 – sequence: 5 fullname: 古賀 満明 – sequence: 6 fullname: 矢野 右人 |
| Author_xml | – sequence: 1 fullname: KOGA, Michiaki organization: Institute for Clinical Research, Nagasaki Chuo National Hospital – sequence: 1 fullname: YATSUHASHI, Hiroshi organization: Institute for Clinical Research, Nagasaki Chuo National Hospital – sequence: 1 fullname: YANO, Michitami organization: Institute for Clinical Research, Nagasaki Chuo National Hospital – sequence: 1 fullname: INOKUCHI, Kaoru organization: Institute for Clinical Research, Nagasaki Chuo National Hospital – sequence: 1 fullname: MATSUMURA, Nobuyuki organization: Institute for Clinical Research, Nagasaki Chuo National Hospital – sequence: 1 fullname: INOUE, Osami organization: Institute for Clinical Research, Nagasaki Chuo National Hospital |
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| DocumentTitleAlternate | Ｃ型肝炎のインターフェロン療法 |
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| References | 2) 高田伸夫, 高瀬修二郎, 高田昭他: C型肝炎ウイルス遺伝子の型分類とその臨床的意義, 肝臓, 33: 121, 1992 4) 矢野右人, 八橋弘, 猪口薫他: DNAプローブ法によるHCV-RNAの定量, 肝胆膵, 25 (5): 931, 1993 3) 荒瀬康司, 茶山一影, 坪田昭人他: HCV-RNA陽性のC型慢性肝炎に対するインターフェロン投与の有効性に関する検討, 肝臓, 34: 1, 1993 1) K Yatsuhashi, O Inoue, K Inokuchi et al: Short and long term effects of interferon on serum markers of hepatitis C virus replication, Journal of Gastroenterology and hepatology, 1993: (in press). |
| References_xml | – reference: 2) 高田伸夫, 高瀬修二郎, 高田昭他: C型肝炎ウイルス遺伝子の型分類とその臨床的意義, 肝臓, 33: 121, 1992 – reference: 3) 荒瀬康司, 茶山一影, 坪田昭人他: HCV-RNA陽性のC型慢性肝炎に対するインターフェロン投与の有効性に関する検討, 肝臓, 34: 1, 1993 – reference: 4) 矢野右人, 八橋弘, 猪口薫他: DNAプローブ法によるHCV-RNAの定量, 肝胆膵, 25 (5): 931, 1993 – reference: 1) K Yatsuhashi, O Inoue, K Inokuchi et al: Short and long term effects of interferon on serum markers of hepatitis C virus replication, Journal of Gastroenterology and hepatology, 1993: (in press). |
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| SubjectTerms | C型肝炎 HCV-genotype HCV-RNA level HCV-RNA量 hepatitis C IFN治療 treatment with IFN |
| Title | INTERFERON TREATMENT OF HEPATITIS C |
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