‘TRANSLUMINAL STAPLOPLASTY’ FOR ATRIAL SEPTAL DEFEDCT [PURPOSE]

• Published in: Jinko Zoki Vol. 25; no. 3; pp. 723 - 727
• Main Authors: INOUE, Y., SANO, Y., UEDA, T., MITSUMARU, A., KAWADA, S., YOZU, R.
• Format: Journal Article
• Language: Japanese
• Published: JAPANESE SOCIETY FOR ARTIFICIAL ORGANS 1996; 一般社団法人 日本人工臓器学会
• Subjects: Atrial Septal Defect; Transluminal Staploplasty
• ISSN: 0300-0818; 1883-6097
• DOI: 10.11392/jsao1972.25.723

To determine the feasibility of transluminal closure of Atrial Septal Defect (ASD) using a staple-catheter device with a guiding catheter in an experimental setting of a beating porcine heart. [METHOD] In 6 porcines under thoracotomy and general anesthesia, intact atrial septum (IAS) was viewed by transluminal cardioscopy, and stapling was attempted at the IAS with a stapler inserted through the trocar guiding catheter via the right atrium under thoracotomy. Then an artificial IAS defect was created with forceps inserted through the guiding catheter, and staploplasty correction for the artificial atrial septal defect was attempted. [RESULTS] The level of injury occuring during percutanous staploplasty was low and the safe anchoring of the staple device was successfully done in 4 subjects. These can be monitored/documented by cardioscope, intercardiac echo device, and post mortem macro-histological examination. [CONCLUSION] Although the size and flexibility of the stapler and the guiding catheter need improvement, our results demonstrate the strong potential for transluminal closure of atrial septal defect using this novel staploplasty technique which could eliminate current necessity of open heart surgery.