ARRHYTHMIA AND DESATURATION DURING SLEEP IN DUCHENNE MUSCLAR DYSTROPHY (DMD)

• Published in: Japanese Journal of National Medical Services Vol. 47; no. 2; pp. 104 - 110
• Main Authors: SHIMOKATA, Kaoru, IIDA, Mitsuo, SAKAI, Motoko, TERASHIMA, Masayoshi, HONDA, Hitoshi, HAYASHI, Hiroshi, YASUMA, Fumihiko, OKADA, Tamotsu
• Format: Journal Article
• Language: Japanese
• Published: Japanese Society of National Medical Services 1993; 一般社団法人 国立医療学会
• Subjects: adesaturation; arrhythmi; arterial oxygen saturation; Duchenne musclar dystrophy; Duchenne型筋ジストロフィー症; Holter electrocardiogram; ホルター型心電計; 不整脈; 低酸素血症; 動脈血酸素飽和度; 睡眠
• ISSN: 0021-1699; 1884-8729
• DOI: 10.11261/iryo1946.47.104

To clarify the relationship between nocturnal arrhythmia and desaturation in DMD, we monitored ECG and oxygen saturation simultaneously in Holter electrocardiogram in 20 DMD in patients. Sustained sinus tachycardia (mean HR>100) was diagnosed in 3 subjects and multifocal vetricular premature beats (VPBs) in ten. Total desaturation time (SaO2<90%) over 11 minutes was diagnosed in six and frequency of desaturation per a night over 11 in eleven. Fifteen patients showed daytime hypoventilation, which was diagnosed by arterial blood PCO2 over 45mmHg. We found nosignificant relation among numbers of VPBs, episodes of tachycardia, mean HR and these desaturation parameters.