Intrahepatic bile duct stones occurred during the long-term follow-up period after the pancreatoduodenectomy for a case with an advanced stage gallbladder carcinoma

A case with multiple stones in the intrahepatic bile duct 5 years after pancreatoduodenectomy is presented. A 67-year-old female was admitted to our hospital because of the symptoms compatible with cholangitis. The patient was diagnosed as stage IVa gallbladder carcinoma 5 years before and underwent...

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Published inTando Vol. 14; no. 2; pp. 147 - 153
Main Authors OCHIAI, Masahiro, JIMBO, Yasuko, HASEGAWA, Shigeru, MIURA, Hirotake, SAKURAI, Yoichi, FUNABIKI, Takahiko, MATSUBARA, Toshiki, SUGANUMA, Masashi, IMAZU, Hiroki
Format Journal Article
LanguageJapanese
Published Japan Biliary Association 2000
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ISSN0914-0077
1883-6879
DOI10.11210/tando1987.14.2_147

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Abstract A case with multiple stones in the intrahepatic bile duct 5 years after pancreatoduodenectomy is presented. A 67-year-old female was admitted to our hospital because of the symptoms compatible with cholangitis. The patient was diagnosed as stage IVa gallbladder carcinoma 5 years before and underwent pancreatoduodenectomy associated with the partial hepatectomy and was reconstructed with a so called “Imanaga I” procedure. No findings indicating the recurrence of carcinoma had been noted during the follow-up period except a sustained and modest increase in plasma CA 19-9 level. Magnetic resonance cholangiopancreatography revealed a dilatation of intrahepatic bile duct and multiple biliary stones. Percutaneous transhepatic biliary drainage was performed and the stones were then removed under cholangioscopy. The cholangioscopy revealed a stenotic choledochojejunostomy of which size was 3 mm in diameter. The dilatation procedure using a balloon catheter was repeatedly performed to facilitate bile flow. No cancer cells were detected either from biopsy specimen obtained from the anastomotic site or bile fluid. A 24-Fr Nelaton catheter was placed in the stenotic site as a stent for 6 months and was then removed. No findings indicating anastomotic stenosis has been noted for 30 months after the removal of the catheter.
AbstractList A case with multiple stones in the intrahepatic bile duct 5 years after pancreatoduodenectomy is presented. A 67-year-old female was admitted to our hospital because of the symptoms compatible with cholangitis. The patient was diagnosed as stage IVa gallbladder carcinoma 5 years before and underwent pancreatoduodenectomy associated with the partial hepatectomy and was reconstructed with a so called “Imanaga I” procedure. No findings indicating the recurrence of carcinoma had been noted during the follow-up period except a sustained and modest increase in plasma CA 19-9 level. Magnetic resonance cholangiopancreatography revealed a dilatation of intrahepatic bile duct and multiple biliary stones. Percutaneous transhepatic biliary drainage was performed and the stones were then removed under cholangioscopy. The cholangioscopy revealed a stenotic choledochojejunostomy of which size was 3 mm in diameter. The dilatation procedure using a balloon catheter was repeatedly performed to facilitate bile flow. No cancer cells were detected either from biopsy specimen obtained from the anastomotic site or bile fluid. A 24-Fr Nelaton catheter was placed in the stenotic site as a stent for 6 months and was then removed. No findings indicating anastomotic stenosis has been noted for 30 months after the removal of the catheter. 進行胆嚢癌(Stage IVa)に対して行った膵頭十二指腸切除術施行5年後に,良性胆管空腸吻合部狭窄により発生した肝内結石症を経験した. 症例は6 7 歳, 女性. 平成4 年Stage IVa胆嚢癌に対して,肝床切除兼膵頭十二指腸切除術,今永I法再建を施行.その後CA19-9の軽度の高値を持続的に認め,再発を疑い検査を施行していたが,再発所見は認めなかった.今回,胆管炎症状を認めたため,精査目的に入院.MRCPにて肝内胆管の拡張と多発する結石像を認め,PTCDを施行した.胆道鏡下に切石し,切石終了後に吻合部を確認すると吻合部は3mm大で胆道鏡は通過せず,同部位を胆道拡張バルーンにて段階的に拡張術を行った.拡張前後の生検では,癌細胞は認めなかった.再狭窄防止のため,ネラトンカテーテル24Frをステントとして留置し,約6カ月後に抜表した.抜去後約2年6カ月経過したが,再狭窄の所見は認めていない.
A case with multiple stones in the intrahepatic bile duct 5 years after pancreatoduodenectomy is presented. A 67-year-old female was admitted to our hospital because of the symptoms compatible with cholangitis. The patient was diagnosed as stage IVa gallbladder carcinoma 5 years before and underwent pancreatoduodenectomy associated with the partial hepatectomy and was reconstructed with a so called “Imanaga I” procedure. No findings indicating the recurrence of carcinoma had been noted during the follow-up period except a sustained and modest increase in plasma CA 19-9 level. Magnetic resonance cholangiopancreatography revealed a dilatation of intrahepatic bile duct and multiple biliary stones. Percutaneous transhepatic biliary drainage was performed and the stones were then removed under cholangioscopy. The cholangioscopy revealed a stenotic choledochojejunostomy of which size was 3 mm in diameter. The dilatation procedure using a balloon catheter was repeatedly performed to facilitate bile flow. No cancer cells were detected either from biopsy specimen obtained from the anastomotic site or bile fluid. A 24-Fr Nelaton catheter was placed in the stenotic site as a stent for 6 months and was then removed. No findings indicating anastomotic stenosis has been noted for 30 months after the removal of the catheter.
Author MATSUBARA, Toshiki
MIURA, Hirotake
SUGANUMA, Masashi
SAKURAI, Yoichi
IMAZU, Hiroki
OCHIAI, Masahiro
FUNABIKI, Takahiko
HASEGAWA, Shigeru
JIMBO, Yasuko
Author_FL 三浦 弘岡
菅沼 正司
船曵 孝彦
長谷川 茂
神保 康子
今津 浩喜
落合 正宏
松原 俊樹
桜井 洋一
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  fullname: 菅沼 正司
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  fullname: 今津 浩喜
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5)原田 昇, 神津照雄, 大島郁也, ほか. 良性胆道狭窄に対する内視鏡的治療. 胆道 1992 ; 6 : 73-8
6) Stephen BV, Richard JH, James C, Irvin FHJ. Evaluation of percutaneous transhepatic balloon dilation of benign biliary strictures in high-risk patients. Am J Surg 1985 ; 149 : 73-9
11)山本雅明, 山城一弘, 大島秀紀, ほか. 肝内結石再発を繰り返した膵頭十二指腸切除術後胆管空腸吻合部良性狭窄の1例. 胆と膵 1999 ; 20 : 523-8
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3)吉岡正智, 田中洋介, 和田勲武, ほか. 膵頭十二指腸切除後に発生した肝内結石症の1例. 胆と膵 1984 ; 5 : 931-6
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7) Yi-Yin J, Miin-Fu C, Chieng-Fu H. Balloon dilation of intrahepatic duct and biliary-enteric a n astomosis strictures. Int Surg 1994 ; 79 : 103-5
1)永川宅和, 萱原正都. 胆道癌治療成績からみた胆道癌治療の実態. 胆道 2000 ; 14 : 23-8
10)岸 清志, 河村良寛私の工夫・手術・処置・手順(1), 胆管空腸吻合術後の吻合部狭窄, 肝内結石症に対する非手術的治療法. 臨外 1994 ; 49 : 1172
References_xml – reference: 6) Stephen BV, Richard JH, James C, Irvin FHJ. Evaluation of percutaneous transhepatic balloon dilation of benign biliary strictures in high-risk patients. Am J Surg 1985 ; 149 : 73-9
– reference: 8)吉岡哲也, 森田荘二郎, 齋藤博哉, ほか. 良性胆管狭窄に対するExpandable Metallic Stent(EMS)の臨床的応用. 胆と膵 1993 ; 14 : 1081-7
– reference: 12)安井智明, 山中若樹, 神野浩樹, ほか. 胆管空腸吻合術後狭窄に対するSelf-Expandable Metallic Stent 留置の臨床的検討. 胆道 1997 ; 11 : 397-402
– reference: 2)小林展章, 高林有道, 蔦原康行, ほか. 実験的肝内結石. 胆と膵 1994 ; 15 : 421-7
– reference: 4)有山 裏, 崔 仁換. MRCP. 膵胆道の新しい画像診断. 東京 ; 中外医学社, 1998 : 58
– reference: 10)岸 清志, 河村良寛私の工夫・手術・処置・手順(1), 胆管空腸吻合術後の吻合部狭窄, 肝内結石症に対する非手術的治療法. 臨外 1994 ; 49 : 1172
– reference: 5)原田 昇, 神津照雄, 大島郁也, ほか. 良性胆道狭窄に対する内視鏡的治療. 胆道 1992 ; 6 : 73-8
– reference: 9)福田直人, 石山純司, 春日井尚, ほか. 術後良性胆管狭窄に対する経皮的胆管拡張術施行例の検討. 日臨外会誌 1998 ; 59 : 2489-94
– reference: 3)吉岡正智, 田中洋介, 和田勲武, ほか. 膵頭十二指腸切除後に発生した肝内結石症の1例. 胆と膵 1984 ; 5 : 931-6
– reference: 7) Yi-Yin J, Miin-Fu C, Chieng-Fu H. Balloon dilation of intrahepatic duct and biliary-enteric a n astomosis strictures. Int Surg 1994 ; 79 : 103-5
– reference: 1)永川宅和, 萱原正都. 胆道癌治療成績からみた胆道癌治療の実態. 胆道 2000 ; 14 : 23-8
– reference: 11)山本雅明, 山城一弘, 大島秀紀, ほか. 肝内結石再発を繰り返した膵頭十二指腸切除術後胆管空腸吻合部良性狭窄の1例. 胆と膵 1999 ; 20 : 523-8
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Snippet A case with multiple stones in the intrahepatic bile duct 5 years after pancreatoduodenectomy is presented. A 67-year-old female was admitted to our hospital...
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StartPage 147
SubjectTerms 肝内結石
膵頭十二指腸切除
良性胆管空腸吻合部狭窄
Title Intrahepatic bile duct stones occurred during the long-term follow-up period after the pancreatoduodenectomy for a case with an advanced stage gallbladder carcinoma
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