THE EFFECT OF GENDER, AGE, AND SYMPTOM SEVERITY IN LATE-LIFE DEPRESSION ON THE RISK OF ALL-CAUSE MORTALITY: THE BAMBUÍ COHORT STUDY OF AGING
Background Increased mortality risk and its moderators is an important, but still under recognized, negative outcome of late‐life depression (LLD). Therefore, we aimed to evaluate whether LLD is a risk factor for all‐cause mortality in a population‐based study with over 10 years of follow‐up, and ad...
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| Published in | Depression and anxiety Vol. 31; no. 9; pp. 787 - 795 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Blackwell Publishing Ltd
01.09.2014
John Wiley & Sons, Inc |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1091-4269 1520-6394 1520-6394 |
| DOI | 10.1002/da.22226 |
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| Abstract | Background
Increased mortality risk and its moderators is an important, but still under recognized, negative outcome of late‐life depression (LLD). Therefore, we aimed to evaluate whether LLD is a risk factor for all‐cause mortality in a population‐based study with over 10 years of follow‐up, and addressed the moderating effect of gender and symptom severity on mortality risk.
Methods
This analysis used data from the Bambuí Cohort Study of Aging. The study population comprised 1.508 (86.5%) of all eligible 1.742 elderly residents. Depressive symptoms were annually evaluated by the GHQ‐12, with scores of five or higher indicating clinically significant depression. From 1997 to 2007, 441 participants died during 10,648 person‐years of follow‐up. We estimated the hazard ratio for mortality risk by Cox regression analyses.
Results
Depressive symptoms were a risk factor for all‐cause mortality after adjusting for confounding lifestyle and clinical factors (adjusted HR = 1.24 CI95% [1.00–1.55], P = .05). Mortality risk was significantly elevated in men (adjusted HR = 1.45 CI95% [1.01–2.07], P = 0.04), but not in women (adjusted HR = 1.13 CI95% [0.84–1.48], P = 0.15). We observed a significant interaction between gender and depressive symptoms on mortality risk ((HR = 1.72 CI95% [1.18–2.49], P = 0.004).
Conclusion
The present study provides evidence that LLD is a risk factor for all‐cause mortality in the elderly, especially in men. The prevention and adequate treatment of LLD may help to reduce premature disability and death among elders with depressive symptoms. |
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| AbstractList | Increased mortality risk and its moderators is an important, but still under recognized, negative outcome of late-life depression (LLD). Therefore, we aimed to evaluate whether LLD is a risk factor for all-cause mortality in a population-based study with over 10 years of follow-up, and addressed the moderating effect of gender and symptom severity on mortality risk.BACKGROUNDIncreased mortality risk and its moderators is an important, but still under recognized, negative outcome of late-life depression (LLD). Therefore, we aimed to evaluate whether LLD is a risk factor for all-cause mortality in a population-based study with over 10 years of follow-up, and addressed the moderating effect of gender and symptom severity on mortality risk.This analysis used data from the Bambuí Cohort Study of Aging. The study population comprised 1.508 (86.5%) of all eligible 1.742 elderly residents. Depressive symptoms were annually evaluated by the GHQ-12, with scores of five or higher indicating clinically significant depression. From 1997 to 2007, 441 participants died during 10,648 person-years of follow-up. We estimated the hazard ratio for mortality risk by Cox regression analyses.METHODSThis analysis used data from the Bambuí Cohort Study of Aging. The study population comprised 1.508 (86.5%) of all eligible 1.742 elderly residents. Depressive symptoms were annually evaluated by the GHQ-12, with scores of five or higher indicating clinically significant depression. From 1997 to 2007, 441 participants died during 10,648 person-years of follow-up. We estimated the hazard ratio for mortality risk by Cox regression analyses.Depressive symptoms were a risk factor for all-cause mortality after adjusting for confounding lifestyle and clinical factors (adjusted HR = 1.24 CI95% [1.00-1.55], P = .05). Mortality risk was significantly elevated in men (adjusted HR = 1.45 CI95% [1.01-2.07], P = 0.04), but not in women (adjusted HR = 1.13 CI95% [0.84-1.48], P = 0.15). We observed a significant interaction between gender and depressive symptoms on mortality risk ((HR = 1.72 CI95% [1.18-2.49], P = 0.004).RESULTSDepressive symptoms were a risk factor for all-cause mortality after adjusting for confounding lifestyle and clinical factors (adjusted HR = 1.24 CI95% [1.00-1.55], P = .05). Mortality risk was significantly elevated in men (adjusted HR = 1.45 CI95% [1.01-2.07], P = 0.04), but not in women (adjusted HR = 1.13 CI95% [0.84-1.48], P = 0.15). We observed a significant interaction between gender and depressive symptoms on mortality risk ((HR = 1.72 CI95% [1.18-2.49], P = 0.004).The present study provides evidence that LLD is a risk factor for all-cause mortality in the elderly, especially in men. The prevention and adequate treatment of LLD may help to reduce premature disability and death among elders with depressive symptoms.CONCLUSIONThe present study provides evidence that LLD is a risk factor for all-cause mortality in the elderly, especially in men. The prevention and adequate treatment of LLD may help to reduce premature disability and death among elders with depressive symptoms. Background Increased mortality risk and its moderators is an important, but still under recognized, negative outcome of late-life depression (LLD). Therefore, we aimed to evaluate whether LLD is a risk factor for all-cause mortality in a population-based study with over 10 years of follow-up, and addressed the moderating effect of gender and symptom severity on mortality risk. Methods This analysis used data from the Bambuí Cohort Study of Aging. The study population comprised 1.508 (86.5%) of all eligible 1.742 elderly residents. Depressive symptoms were annually evaluated by the GHQ-12, with scores of five or higher indicating clinically significant depression. From 1997 to 2007, 441 participants died during 10,648 person-years of follow-up. We estimated the hazard ratio for mortality risk by Cox regression analyses. Results Depressive symptoms were a risk factor for all-cause mortality after adjusting for confounding lifestyle and clinical factors (adjusted HR = 1.24 CI95% [1.00-1.55], P = .05). Mortality risk was significantly elevated in men (adjusted HR = 1.45 CI95% [1.01-2.07], P = 0.04), but not in women (adjusted HR = 1.13 CI95% [0.84-1.48], P = 0.15). We observed a significant interaction between gender and depressive symptoms on mortality risk ((HR = 1.72 CI95% [1.18-2.49], P = 0.004). Conclusion The present study provides evidence that LLD is a risk factor for all-cause mortality in the elderly, especially in men. The prevention and adequate treatment of LLD may help to reduce premature disability and death among elders with depressive symptoms. [PUBLICATION ABSTRACT] Increased mortality risk and its moderators is an important, but still under recognized, negative outcome of late-life depression (LLD). Therefore, we aimed to evaluate whether LLD is a risk factor for all-cause mortality in a population-based study with over 10 years of follow-up, and addressed the moderating effect of gender and symptom severity on mortality risk. This analysis used data from the Bambuí Cohort Study of Aging. The study population comprised 1.508 (86.5%) of all eligible 1.742 elderly residents. Depressive symptoms were annually evaluated by the GHQ-12, with scores of five or higher indicating clinically significant depression. From 1997 to 2007, 441 participants died during 10,648 person-years of follow-up. We estimated the hazard ratio for mortality risk by Cox regression analyses. Depressive symptoms were a risk factor for all-cause mortality after adjusting for confounding lifestyle and clinical factors (adjusted HR = 1.24 CI95% [1.00-1.55], P = .05). Mortality risk was significantly elevated in men (adjusted HR = 1.45 CI95% [1.01-2.07], P = 0.04), but not in women (adjusted HR = 1.13 CI95% [0.84-1.48], P = 0.15). We observed a significant interaction between gender and depressive symptoms on mortality risk ((HR = 1.72 CI95% [1.18-2.49], P = 0.004). The present study provides evidence that LLD is a risk factor for all-cause mortality in the elderly, especially in men. The prevention and adequate treatment of LLD may help to reduce premature disability and death among elders with depressive symptoms. Background Increased mortality risk and its moderators is an important, but still under recognized, negative outcome of late‐life depression (LLD). Therefore, we aimed to evaluate whether LLD is a risk factor for all‐cause mortality in a population‐based study with over 10 years of follow‐up, and addressed the moderating effect of gender and symptom severity on mortality risk. Methods This analysis used data from the Bambuí Cohort Study of Aging. The study population comprised 1.508 (86.5%) of all eligible 1.742 elderly residents. Depressive symptoms were annually evaluated by the GHQ‐12, with scores of five or higher indicating clinically significant depression. From 1997 to 2007, 441 participants died during 10,648 person‐years of follow‐up. We estimated the hazard ratio for mortality risk by Cox regression analyses. Results Depressive symptoms were a risk factor for all‐cause mortality after adjusting for confounding lifestyle and clinical factors (adjusted HR = 1.24 CI95% [1.00–1.55], P = .05). Mortality risk was significantly elevated in men (adjusted HR = 1.45 CI95% [1.01–2.07], P = 0.04), but not in women (adjusted HR = 1.13 CI95% [0.84–1.48], P = 0.15). We observed a significant interaction between gender and depressive symptoms on mortality risk ((HR = 1.72 CI95% [1.18–2.49], P = 0.004). Conclusion The present study provides evidence that LLD is a risk factor for all‐cause mortality in the elderly, especially in men. The prevention and adequate treatment of LLD may help to reduce premature disability and death among elders with depressive symptoms. |
| Author | Diniz, Breno S. Firmo, Josélia O. A. Dew, Mary Amanda Castro-Costa, Erico Reynolds III, Charles F. Lima-Costa, Maria Fernanda Butters, Meryl A. |
| AuthorAffiliation | 4 Department of Social and Preventive Medicine, Federal University of Minas Gerais Medical School, Belo Horizonte, MG, Brazil 2 Department of Psychiatry, University of Pittsburgh Medical School, Pittsburgh, PA, USA 1 Department of Mental Health, Federal University of Minas Gerais Medical School, Belo Horizonte, MG, Brazil 3 René Rachou Research Center, Oswaldo Cruz Foundation, Belo Horizonte, MG, Brazil |
| AuthorAffiliation_xml | – name: 2 Department of Psychiatry, University of Pittsburgh Medical School, Pittsburgh, PA, USA – name: 1 Department of Mental Health, Federal University of Minas Gerais Medical School, Belo Horizonte, MG, Brazil – name: 3 René Rachou Research Center, Oswaldo Cruz Foundation, Belo Horizonte, MG, Brazil – name: 4 Department of Social and Preventive Medicine, Federal University of Minas Gerais Medical School, Belo Horizonte, MG, Brazil |
| Author_xml | – sequence: 1 givenname: Breno S. surname: Diniz fullname: Diniz, Breno S. email: Correspondence to: Breno Satler Diniz, M.D., Ph.D., Department of Mental Health, Federal University of Minas Gerais Medical School, Av. Alfredo Balena, 190, Belo Horizonte, MG 30130, Brazil., brenosatler@gmail.com organization: Department of Mental Health, Federal University of Minas Gerais Medical School, MG, Belo Horizonte, Brazil – sequence: 2 givenname: Charles F. surname: Reynolds III fullname: Reynolds III, Charles F. organization: Department of Psychiatry, University of Pittsburgh Medical School, PA, Pittsburgh, USA – sequence: 3 givenname: Meryl A. surname: Butters fullname: Butters, Meryl A. organization: Department of Psychiatry, University of Pittsburgh Medical School, PA, Pittsburgh, USA – sequence: 4 givenname: Mary Amanda surname: Dew fullname: Dew, Mary Amanda organization: Department of Psychiatry, University of Pittsburgh Medical School, PA, Pittsburgh, USA – sequence: 5 givenname: Josélia O. A. surname: Firmo fullname: Firmo, Josélia O. A. organization: René Rachou Research Center, Oswaldo Cruz Foundation, MG, Belo Horizonte, Brazil – sequence: 6 givenname: Maria Fernanda surname: Lima-Costa fullname: Lima-Costa, Maria Fernanda organization: René Rachou Research Center, Oswaldo Cruz Foundation, Belo Horizonte, MG, Brazil – sequence: 7 givenname: Erico surname: Castro-Costa fullname: Castro-Costa, Erico organization: René Rachou Research Center, Oswaldo Cruz Foundation, Belo Horizonte, MG, Brazil |
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| References | Castro-Costa E, Lima-Costa MF, Carvalhais S, Firmo JO, Uchoa E. Factors associated with depressive symptoms measured by the 12-item General Health Questionnaire in community-dwelling older adults (The Bambuí Health Aging Study). Rev Bras Psiquiatr 2008;30:104-109. Byers AL, Yaffe K, Covinsky KE, Friedman MB, Bruce ML. High occurrence of mood and anxiety disorders among older adults: The National Comorbidity Survey Replication. Arch Gen Psychiatry 2010;67:489-496. Fredman L, Magaziner J, Hebel JR, Hawkes W, Zimmerman SI. Depressive symptoms and 6-year mortality among elderly community-dwelling women. Epidemiology 1999;10:54-59. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 2003;26(Suppl 1):S5-S20. Fuhrer R, Dufouil C, Antonucci TC, Shipley MJ, Helmer C, Dartigues JF. Psychological disorder and mortality in French older adults: do social relations modify the association? Am J Epidemiol 1999;149:116-126. Costa MF, Uchoa E, Guerra HL, Firmo JO, Vidigal PG, Barreto SM. The Bambui health and ageing study (BHAS): methodological approach and preliminary results of a population-based cohort study of the elderly in Brazil. Rev Saude Publica 2000;34:126-135. Sun W, Schooling CM, Chan WM, Ho KS, Lam TH. The association between depressive symptoms and mortality among Chinese elderly: a Hong Kong cohort study. J Gerontol A Biol Sci Med Sci. 2011;66:459-466. Cuijpers P, Beekman AT, Reynolds CF, 3rd. Preventing depression: a global priority. JAMA 2012;307:1033-1034. Alexandrino-Silva C, Wang YP, Carmen Viana M, Bulhoes RS, Martins SS, Andrade LH. Gender differences in symptomatic profiles of depression: results from the Sao Paulo Megacity Mental Health Survey. J Affect Disord. May 2013;147:355-364. Reynolds CF, 3rd, Cuijpers P, Patel V, et al. Early intervention to reduce the global health and economic burden of major depression in older adults. Annu Rev Public Health 2012;33:123-135. Jeong HG, Lee JJ, Lee SB, et al. Role of severity and gender in the association between late-life depression and all-cause mortality. Int Psychogeriatr 2013;25:677-684. Gallo JJ, Morales KH, Bogner HR, et al. Long term effect of depression care management on mortality in older adults: follow-up of cluster randomized clinical trial in primary care. BMJ 2013;346:f2570. van Gool CH, Kempen GI, Penninx BW, Deeg DJ, Beekman AT, van Eijk JT. Relationship between changes in depressive symptoms and unhealthy lifestyles in late middle aged and older persons: results from the Longitudinal Aging Study Amsterdam. Age Ageing 2003;32:81-87. Viana MC, Andrade LH. Lifetime Prevalence, age and gender distribution and age-of-onset of psychiatric disorders in the Sao Paulo Metropolitan Area, Brazil: results from the Sao Paulo Megacity Mental Health Survey. Rev Bras Psiquiatr 2012;34:249-260. McKinney BC, Oh H, Sibille E. Age-by-disease biological interactions: implications for late-life depression. Front Genet 2012;3:237. Ryan J, Carriere I, Ritchie K, et al. Late-life depression and mortality: influence of gender and antidepressant use. Br J Psychiatry 2008;192:12-18. Gorman JM. Gender differences in depression and response to psychotropic medication. Gender Med 2006;3:93-109. Hidalgo CA, Blumm N, Barabasi AL, Christakis NA. A dynamic network approach for the study of human phenotypes. PLoS Comput Biol 2009;5:e1000353. Candore G, Caruso C, Jirillo E, Magrone T, Vasto S. Low grade inflammation as a common pathogenetic denominator in age-related diseases: novel drug targets for anti-ageing strategies and successful ageing achievement. Curr Pharm Des 2010;16:584-596. Costa E, Barreto SM, Uchoa E, Firmo JO, Lima-Costa MF, Prince M. Is the GDS-30 better than the GHQ-12 for screening depression in elderly people in the community? The Bambui Health Aging Study (BHAS). Int Psychogeriatr 2006;18:493-503. Cuijpers P, Vogelzangs N, Twisk J, Kleiboer A, Li J, Penninx BW. Differential mortality rates in major and subthreshold depression: meta-analysis of studies that measured both. Br J Psychiatry 2013;202:22-27. Diniz BS, Teixeira AL, Talib LL, Mendonca VA, Gattaz WF, Forlenza OV. Increased soluble TNF receptor 2 in antidepressant-free patients with late-life depression. J Psychiatr Res 2010;44:917-920. Castro-Costa E, Fuzikawa C, Uchoa E, Firmo JO, Lima-Costa MF. Norms for the mini-mental state examination: adjustment of the cut-off point in population-based studies (evidences from the Bambuí health aging study). Arq Neuropsiquiatr 2008;66:524-528. Mikkola TS, Gissler M, Merikukka M, Tuomikoski P, Ylikorkala O. Sex differences in age-related cardiovascular mortality. PLoS One 2013;8:e63347. Diniz BS, Teixeira AL, Machado-Vieira R, Talib LL, Gattaz WF, Forlenza OV. Reduced serum nerve growth factor in patients with late-life depression. Am J Geriatr Psychiatry 2013;21:493-496. Diniz BS, Teixeira AL, Campos AC, et al. Reduced serum levels of adiponectin in elderly patients with major depression. J Psychiatr Res 2012;46:1081-1085. Goldberg DP, Blackwell B. Psychiatric illness in general practice. A detailed study using a new method of case identification. BMJ 1970;1:439-443. Butters MA, Whyte EM, Nebes RD, et al. The nature and determinants of neuropsychological functioning in late-life depression. Arch Gen Psychiatry 2004;61:587-595. Vaccarino V, Badimon L, Corti R, et al. Ischaemic heart disease in women: are there sex differences in pathophysiology and risk factors? Position paper from the working group on coronary pathophysiology and microcirculation of the European Society of Cardiology. Cardiovascular Res 2011;90:9-17. Wong SY, Mercer SW, Woo J, Leung J. The influence of multi-morbidity and self-reported socio-economic standing on the prevalence of depression in an elderly Hong Kong population. BMC Public Health 2008;8:119. McCaffery JM, Frasure-Smith N, Dube MP, et al. Common genetic vulnerability to depressive symptoms and coronary artery disease: a review and development of candidate genes related to inflammation and serotonin. Psychosom Med 2006;68:187-200. Fu CC, Lee YM, Chen JD. Association between depressive symptoms and twelve-year mortality among elderly in a rural community in Taiwan. J Formos Med Assoc 2003;102:234-239. Jotheeswaran AT, Williams JD, Prince MJ. Predictors of mortality among elderly people living in a south Indian urban community; a 10/66 Dementia Research Group prospective population-based cohort study. BMC Public Health 2010;10:366. Lima-Costa MF, Firmo JO, Uchoa E. Cohort profile: the Bambui (Brazil) Cohort Study of Ageing. Int J Epidemiol 2011;40:862-867. Chobanian AV, Bakris GL, Black HR, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 2003;42:1206-1252. Juster RP, McEwen BS, Lupien SJ. Allostatic load biomarkers of chronic stress and impact on health and cognition. Neurosci Biobehav Rev 2010;35:2-16. Kohler S, Verhey F, Weyerer S, et al. Depression, non-fatal stroke and all-cause mortality in old age: A prospective cohort study of primary care patients. J Affect Disord 2013;150(1):63-69. doi:10.1016/j.jad.2013.02.020. Schoevers RA, Geerlings MI, Beekman AT, et al. Association of depression and gender with mortality in old age. Results from the Amsterdam Study of the Elderly (AMSTEL). Br J Psychiatry 2000;177:336-342. Diniz BS, Talib LL, Joaquim HP, de Paula VR, Gattaz WF, Forlenza OV. Platelet GSK3B activity in patients with late-life depression: marker of depressive episode severity and cognitive impairment? World J Biol Psychiatry 2011;12:216-222. Katz S, Downs TD, Cash HR, Grotz RC. Progress in development of the index of ADL. Gerontologist 1970;10:20-30. Penninx BW, Geerlings SW, Deeg DJ, van Eijk JT, van Tilburg W, Beekman AT. Minor and major depression and the risk of death in older persons. Arch Gen Psychiatry 1999;56:889-895. Li N, Pang L, Chen G, Song X, Zhang J, Zheng X. Risk factors for depression in older adults in Beijing. Can J Psychiatry 2011;56:466-473. Rathcke CN, Raymond I, Kistorp C, Hildebrandt P, Faber J, Vestergaard H. Low grade inflammation as measured by levels of YKL-40: association with an increased overall and cardiovascular mortality rate in an elderly population. Int J Cardiol 2010;143:35-42. Dimopoulos N, Piperi C, Psarra V, Lea RW, Kalofoutis A. Increased plasma levels of 8-iso-PGF2alpha and IL-6 in an elderly population with depression. Psychiatry Res 2008;161:59-66. Lyness JM, Niculescu A, Tu X, Reynolds CF, 3rd, Caine ED. The relationship of medical comorbidity and depression in older, primary care patients. Psychosomatics 2006;47:435-439. Diniz BS, Butters MA, Albert SM, Dew MA, Reynolds CF, 3rd. Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies. Br J Psychiatry 2013;202:329-335. Wolkowitz OM, Mellon SH, Epel ES, et al. Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress-preliminary findings. PLoS One 2011;6:e17837. Almeida OP, Alfonso H, Hankey GJ, Flicker L. Depression, antidepressant use and mortality in later life: the Health In Men Study. PLoS One 2010;5:e11266. Wium-Andersen MK, Orsted DD, Nielsen SF, Nordestgaard BG. Elevated C-reactive protein levels, psychological distress, and depression in 73, 131 individuals. JAMA Psychiatry 2013;70:176-184. Hybels CF, Pieper CF, Blazer DG. Sex differences in the relationship between subthreshold depression and mortality in a community sample of older adults. Am J Geriatr Psychiatry 2002;10:283-291. Penninx BW, Beekman AT, Bandinelli S, et al. Late-life depressive symptoms are associated with both hyperactivity and hypoactivity of the hypothalamo-pituitary-adrenal axis. Am J Geriatr Psychiatry 2007;15:522-529. Yen YC, Rebok GW, Gallo JJ, Jones RN, Tennstedt SL. Depressive symptoms impair everyday problem-solving ability through cognit 2008; 192 2010; 10 2004; 61 2010; 16 2013; 25 2013; 21 2002; 10 2010; 143 2013; 202 2008; 8 2013; 70 2011; 12 2011; 56 2000; 177 2008; 30 1970; 1 2013; 8 2011; 19 2010; 67 2006; 68 1999; 56 2011; 66 1999; 10 2008; 66 2010; 5 2013; 150 2003; 42 2009; 66 2010; 35 2013; 346 2011; 40 2006; 18 1970; 10 2013; 147 2006; 3 2012; 34 2011; 6 1999; 149 2012; 33 2003; 32 2007; 15 2008; 161 2012; 307 2010; 44 2012; 3 2000; 34 2011; 90 2006; 47 2003; 26 2009; 5 2012; 46 2003; 102 12540353 - Age Ageing. 2003 Jan;32(1):81-7 21448457 - PLoS One. 2011;6(3):e17837 11116775 - Br J Psychiatry. 2000 Oct;177:336-42 20585644 - PLoS One. 2010;5(6):e11266 10881147 - Rev Saude Publica. 2000 Apr;34(2):126-35 20388068 - Curr Pharm Des. 2010;16(6):584-96 18470408 - Rev Bras Psiquiatr. 2008 Jun;30(2):104-9 18174502 - Br J Psychiatry. 2008 Jan;192(1):12-8 23162569 - Front Genet. 2012 Nov 16;3:237 23738992 - BMJ. 2013;346:f2570 23266538 - JAMA Psychiatry. 2013 Feb;70(2):176-84 18813712 - Arq Neuropsiquiatr. 2008 Sep;66(3A):524-8 16860269 - Gend Med. 2006 Jun;3(2):93-109 19154855 - J Psychosom Res. 2009 Feb;66(2):127-35 18410677 - BMC Public Health. 2008;8:119 23700418 - PLoS One. 2013;8(5):e63347 23570892 - Am J Geriatr Psychiatry. 2013 May;21(5):493-6 21106705 - J Gerontol A Biol Sci Med Sci. 2011 Apr;66(4):459-66 9921956 - Am J Epidemiol. 1999 Jan 15;149(2):116-26 20805109 - Int J Epidemiol. 2011 Aug;40(4):862-7 9888280 - Epidemiology. 1999 Jan;10(1):54-9 22633396 - J Psychiatr Res. 2012 Aug;46(8):1081-5 23429770 - Rev Bras Psiquiatr. 2012 Oct;34(3):249-60 21878157 - Can J Psychiatry. 2011 Aug;56(8):466-73 20573243 - BMC Public Health. 2010;10:366 16478572 - Int Psychogeriatr. 2006 Sep;18(3):493-503 11994215 - Am J Geriatr Psychiatry. 2002 May-Jun;10(3):283-91 18783834 - Psychiatry Res. 2008 Oct 30;161(1):59-66 23284149 - Br J Psychiatry. 2013 Jan;202(1):22-7 12833186 - J Formos Med Assoc. 2003 Apr;102(4):234-9 20338581 - J Psychiatr Res. 2010 Oct;44(14):917-20 23474092 - J Affect Disord. 2013 Aug 15;150(1):63-9 20439830 - Arch Gen Psychiatry. 2010 May;67(5):489-96 15184238 - Arch Gen Psychiatry. 2004 Jun;61(6):587-95 21314327 - World J Biol Psychiatry. 2011 Apr;12(3):216-22 10530630 - Arch Gen Psychiatry. 1999 Oct;56(10):889-95 23256908 - Int Psychogeriatr. 2013 Apr;25(4):677-84 19223085 - Int J Cardiol. 2010 Aug 6;143(1):35-42 19360091 - PLoS Comput Biol. 2009 Apr;5(4):e1000353 14656957 - Hypertension. 2003 Dec;42(6):1206-52 22429161 - Annu Rev Public Health. 2012 Apr;33:123-35 16959933 - Psychosomatics. 2006 Sep-Oct;47(5):435-9 16554382 - Psychosom Med. 2006 Mar-Apr;68(2):187-200 19822172 - Neurosci Biobehav Rev. 2010 Sep;35(1):2-16 23637108 - Br J Psychiatry. 2013 May;202(5):329-35 12502614 - Diabetes Care. 2003 Jan;26 Suppl 1:S5-20 5420677 - Gerontologist. 1970 Spring;10(1):20-30 17545451 - Am J Geriatr Psychiatry. 2007 Jun;15(6):522-9 5420206 - Br Med J. 1970 May 23;1(5707):439-43 23246363 - J Affect Disord. 2013 May;147(1-3):355-64 21159671 - Cardiovasc Res. 2011 Apr 1;90(1):9-17 22416097 - JAMA. 2012 Mar 14;307(10):1033-4 20808123 - Am J Geriatr Psychiatry. 2011 Feb;19(2):142-50 |
| References_xml | – reference: Viana MC, Andrade LH. Lifetime Prevalence, age and gender distribution and age-of-onset of psychiatric disorders in the Sao Paulo Metropolitan Area, Brazil: results from the Sao Paulo Megacity Mental Health Survey. Rev Bras Psiquiatr 2012;34:249-260. – reference: Penninx BW, Geerlings SW, Deeg DJ, van Eijk JT, van Tilburg W, Beekman AT. Minor and major depression and the risk of death in older persons. Arch Gen Psychiatry 1999;56:889-895. – reference: Fu CC, Lee YM, Chen JD. Association between depressive symptoms and twelve-year mortality among elderly in a rural community in Taiwan. J Formos Med Assoc 2003;102:234-239. – reference: Penninx BW, Beekman AT, Bandinelli S, et al. Late-life depressive symptoms are associated with both hyperactivity and hypoactivity of the hypothalamo-pituitary-adrenal axis. Am J Geriatr Psychiatry 2007;15:522-529. – reference: Gallo JJ, Morales KH, Bogner HR, et al. Long term effect of depression care management on mortality in older adults: follow-up of cluster randomized clinical trial in primary care. BMJ 2013;346:f2570. – reference: Castro-Costa E, Fuzikawa C, Uchoa E, Firmo JO, Lima-Costa MF. Norms for the mini-mental state examination: adjustment of the cut-off point in population-based studies (evidences from the Bambuí health aging study). Arq Neuropsiquiatr 2008;66:524-528. – reference: Cuijpers P, Beekman AT, Reynolds CF, 3rd. Preventing depression: a global priority. JAMA 2012;307:1033-1034. – reference: Hybels CF, Pieper CF, Blazer DG. Sex differences in the relationship between subthreshold depression and mortality in a community sample of older adults. Am J Geriatr Psychiatry 2002;10:283-291. – reference: Diniz BS, Talib LL, Joaquim HP, de Paula VR, Gattaz WF, Forlenza OV. Platelet GSK3B activity in patients with late-life depression: marker of depressive episode severity and cognitive impairment? World J Biol Psychiatry 2011;12:216-222. – reference: Gallegos-Carrillo K, Garcia-Pena C, Mudgal J, Romero X, Duran-Arenas L, Salmeron J. Role of depressive symptoms and comorbid chronic disease on health-related quality of life among community-dwelling older adults. J Psychosom Res 2009;66:127-135. – reference: Almeida OP, Alfonso H, Hankey GJ, Flicker L. Depression, antidepressant use and mortality in later life: the Health In Men Study. PLoS One 2010;5:e11266. – reference: McKinney BC, Oh H, Sibille E. Age-by-disease biological interactions: implications for late-life depression. Front Genet 2012;3:237. – reference: Gorman JM. Gender differences in depression and response to psychotropic medication. Gender Med 2006;3:93-109. – reference: Alexandrino-Silva C, Wang YP, Carmen Viana M, Bulhoes RS, Martins SS, Andrade LH. Gender differences in symptomatic profiles of depression: results from the Sao Paulo Megacity Mental Health Survey. J Affect Disord. May 2013;147:355-364. – reference: Costa E, Barreto SM, Uchoa E, Firmo JO, Lima-Costa MF, Prince M. Is the GDS-30 better than the GHQ-12 for screening depression in elderly people in the community? The Bambui Health Aging Study (BHAS). Int Psychogeriatr 2006;18:493-503. – reference: Wolkowitz OM, Mellon SH, Epel ES, et al. Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress-preliminary findings. PLoS One 2011;6:e17837. – reference: Ryan J, Carriere I, Ritchie K, et al. Late-life depression and mortality: influence of gender and antidepressant use. Br J Psychiatry 2008;192:12-18. – reference: Schoevers RA, Geerlings MI, Beekman AT, et al. Association of depression and gender with mortality in old age. Results from the Amsterdam Study of the Elderly (AMSTEL). Br J Psychiatry 2000;177:336-342. – reference: Diniz BS, Teixeira AL, Campos AC, et al. Reduced serum levels of adiponectin in elderly patients with major depression. J Psychiatr Res 2012;46:1081-1085. – reference: Li N, Pang L, Chen G, Song X, Zhang J, Zheng X. Risk factors for depression in older adults in Beijing. Can J Psychiatry 2011;56:466-473. – reference: Costa MF, Uchoa E, Guerra HL, Firmo JO, Vidigal PG, Barreto SM. The Bambui health and ageing study (BHAS): methodological approach and preliminary results of a population-based cohort study of the elderly in Brazil. Rev Saude Publica 2000;34:126-135. – reference: Diniz BS, Teixeira AL, Machado-Vieira R, Talib LL, Gattaz WF, Forlenza OV. Reduced serum nerve growth factor in patients with late-life depression. Am J Geriatr Psychiatry 2013;21:493-496. – reference: Wong SY, Mercer SW, Woo J, Leung J. The influence of multi-morbidity and self-reported socio-economic standing on the prevalence of depression in an elderly Hong Kong population. BMC Public Health 2008;8:119. – reference: Hidalgo CA, Blumm N, Barabasi AL, Christakis NA. A dynamic network approach for the study of human phenotypes. PLoS Comput Biol 2009;5:e1000353. – reference: Juster RP, McEwen BS, Lupien SJ. Allostatic load biomarkers of chronic stress and impact on health and cognition. Neurosci Biobehav Rev 2010;35:2-16. – reference: Dimopoulos N, Piperi C, Psarra V, Lea RW, Kalofoutis A. Increased plasma levels of 8-iso-PGF2alpha and IL-6 in an elderly population with depression. Psychiatry Res 2008;161:59-66. – reference: Cuijpers P, Vogelzangs N, Twisk J, Kleiboer A, Li J, Penninx BW. Differential mortality rates in major and subthreshold depression: meta-analysis of studies that measured both. Br J Psychiatry 2013;202:22-27. – reference: Lyness JM, Niculescu A, Tu X, Reynolds CF, 3rd, Caine ED. The relationship of medical comorbidity and depression in older, primary care patients. Psychosomatics 2006;47:435-439. – reference: Rathcke CN, Raymond I, Kistorp C, Hildebrandt P, Faber J, Vestergaard H. Low grade inflammation as measured by levels of YKL-40: association with an increased overall and cardiovascular mortality rate in an elderly population. Int J Cardiol 2010;143:35-42. – reference: Wium-Andersen MK, Orsted DD, Nielsen SF, Nordestgaard BG. Elevated C-reactive protein levels, psychological distress, and depression in 73, 131 individuals. JAMA Psychiatry 2013;70:176-184. – reference: McCaffery JM, Frasure-Smith N, Dube MP, et al. Common genetic vulnerability to depressive symptoms and coronary artery disease: a review and development of candidate genes related to inflammation and serotonin. Psychosom Med 2006;68:187-200. – reference: Butters MA, Whyte EM, Nebes RD, et al. The nature and determinants of neuropsychological functioning in late-life depression. Arch Gen Psychiatry 2004;61:587-595. – reference: Vaccarino V, Badimon L, Corti R, et al. Ischaemic heart disease in women: are there sex differences in pathophysiology and risk factors? Position paper from the working group on coronary pathophysiology and microcirculation of the European Society of Cardiology. Cardiovascular Res 2011;90:9-17. – reference: Mikkola TS, Gissler M, Merikukka M, Tuomikoski P, Ylikorkala O. Sex differences in age-related cardiovascular mortality. PLoS One 2013;8:e63347. – reference: Fuhrer R, Dufouil C, Antonucci TC, Shipley MJ, Helmer C, Dartigues JF. Psychological disorder and mortality in French older adults: do social relations modify the association? Am J Epidemiol 1999;149:116-126. – reference: Yen YC, Rebok GW, Gallo JJ, Jones RN, Tennstedt SL. Depressive symptoms impair everyday problem-solving ability through cognitive abilities in late life. Am J Geriatr Psychiatry 2011;19:142-150. – reference: Fredman L, Magaziner J, Hebel JR, Hawkes W, Zimmerman SI. Depressive symptoms and 6-year mortality among elderly community-dwelling women. Epidemiology 1999;10:54-59. – reference: Byers AL, Yaffe K, Covinsky KE, Friedman MB, Bruce ML. High occurrence of mood and anxiety disorders among older adults: The National Comorbidity Survey Replication. Arch Gen Psychiatry 2010;67:489-496. – reference: van Gool CH, Kempen GI, Penninx BW, Deeg DJ, Beekman AT, van Eijk JT. Relationship between changes in depressive symptoms and unhealthy lifestyles in late middle aged and older persons: results from the Longitudinal Aging Study Amsterdam. Age Ageing 2003;32:81-87. – reference: Lima-Costa MF, Firmo JO, Uchoa E. Cohort profile: the Bambui (Brazil) Cohort Study of Ageing. Int J Epidemiol 2011;40:862-867. – reference: Candore G, Caruso C, Jirillo E, Magrone T, Vasto S. Low grade inflammation as a common pathogenetic denominator in age-related diseases: novel drug targets for anti-ageing strategies and successful ageing achievement. Curr Pharm Des 2010;16:584-596. – reference: Goldberg DP, Blackwell B. Psychiatric illness in general practice. A detailed study using a new method of case identification. BMJ 1970;1:439-443. – reference: Katz S, Downs TD, Cash HR, Grotz RC. Progress in development of the index of ADL. Gerontologist 1970;10:20-30. – reference: Jotheeswaran AT, Williams JD, Prince MJ. Predictors of mortality among elderly people living in a south Indian urban community; a 10/66 Dementia Research Group prospective population-based cohort study. BMC Public Health 2010;10:366. – reference: Castro-Costa E, Lima-Costa MF, Carvalhais S, Firmo JO, Uchoa E. Factors associated with depressive symptoms measured by the 12-item General Health Questionnaire in community-dwelling older adults (The Bambuí Health Aging Study). Rev Bras Psiquiatr 2008;30:104-109. – reference: Sun W, Schooling CM, Chan WM, Ho KS, Lam TH. The association between depressive symptoms and mortality among Chinese elderly: a Hong Kong cohort study. J Gerontol A Biol Sci Med Sci. 2011;66:459-466. – reference: Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 2003;26(Suppl 1):S5-S20. – reference: Diniz BS, Butters MA, Albert SM, Dew MA, Reynolds CF, 3rd. Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies. Br J Psychiatry 2013;202:329-335. – reference: Jeong HG, Lee JJ, Lee SB, et al. Role of severity and gender in the association between late-life depression and all-cause mortality. Int Psychogeriatr 2013;25:677-684. – reference: Diniz BS, Teixeira AL, Talib LL, Mendonca VA, Gattaz WF, Forlenza OV. Increased soluble TNF receptor 2 in antidepressant-free patients with late-life depression. J Psychiatr Res 2010;44:917-920. – reference: Kohler S, Verhey F, Weyerer S, et al. Depression, non-fatal stroke and all-cause mortality in old age: A prospective cohort study of primary care patients. J Affect Disord 2013;150(1):63-69. doi:10.1016/j.jad.2013.02.020. – reference: Chobanian AV, Bakris GL, Black HR, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 2003;42:1206-1252. – reference: Reynolds CF, 3rd, Cuijpers P, Patel V, et al. Early intervention to reduce the global health and economic burden of major depression in older adults. Annu Rev Public Health 2012;33:123-135. – volume: 35 start-page: 2 year: 2010 end-page: 16 article-title: Allostatic load biomarkers of chronic stress and impact on health and cognition publication-title: Neurosci Biobehav Rev – volume: 68 start-page: 187 year: 2006 end-page: 200 article-title: Common genetic vulnerability to depressive symptoms and coronary artery disease: a review and development of candidate genes related to inflammation and serotonin publication-title: Psychosom Med – volume: 147 start-page: 355 year: 2013 end-page: 364 article-title: Gender differences in symptomatic profiles of depression: results from the Sao Paulo Megacity Mental Health Survey publication-title: J Affect Disord. – volume: 21 start-page: 493 year: 2013 end-page: 496 article-title: Reduced serum nerve growth factor in patients with late‐life depression publication-title: Am J Geriatr Psychiatry – volume: 67 start-page: 489 year: 2010 end-page: 496 article-title: High occurrence of mood and anxiety disorders among older adults: The National Comorbidity Survey Replication publication-title: Arch Gen Psychiatry – volume: 1 start-page: 439 year: 1970 end-page: 443 article-title: Psychiatric illness in general practice. A detailed study using a new method of case identification publication-title: BMJ – volume: 19 start-page: 142 year: 2011 end-page: 150 article-title: Depressive symptoms impair everyday problem‐solving ability through cognitive abilities in late life publication-title: Am J Geriatr Psychiatry – volume: 10 start-page: 20 year: 1970 end-page: 30 article-title: Progress in development of the index of ADL publication-title: Gerontologist – volume: 202 start-page: 329 year: 2013 end-page: 335 article-title: Late‐life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta‐analysis of community‐based cohort studies publication-title: Br J Psychiatry – volume: 56 start-page: 466 year: 2011 end-page: 473 article-title: Risk factors for depression in older adults in Beijing publication-title: Can J Psychiatry – volume: 46 start-page: 1081 year: 2012 end-page: 1085 article-title: Reduced serum levels of adiponectin in elderly patients with major depression publication-title: J Psychiatr Res – volume: 25 start-page: 677 year: 2013 end-page: 684 article-title: Role of severity and gender in the association between late‐life depression and all‐cause mortality publication-title: Int Psychogeriatr – volume: 70 start-page: 176 year: 2013 end-page: 184 article-title: Elevated C‐reactive protein levels, psychological distress, and depression in 73, 131 individuals publication-title: JAMA Psychiatry – volume: 3 start-page: 93 year: 2006 end-page: 109 article-title: Gender differences in depression and response to psychotropic medication publication-title: Gender Med – volume: 34 start-page: 126 year: 2000 end-page: 135 article-title: The Bambui health and ageing study (BHAS): methodological approach and preliminary results of a population‐based cohort study of the elderly in Brazil publication-title: Rev Saude Publica – volume: 32 start-page: 81 year: 2003 end-page: 87 article-title: Relationship between changes in depressive symptoms and unhealthy lifestyles in late middle aged and older persons: results from the Longitudinal Aging Study Amsterdam publication-title: Age Ageing – volume: 15 start-page: 522 year: 2007 end-page: 529 article-title: Late‐life depressive symptoms are associated with both hyperactivity and hypoactivity of the hypothalamo‐pituitary‐adrenal axis publication-title: Am J Geriatr Psychiatry – volume: 10 start-page: 366 year: 2010 article-title: Predictors of mortality among elderly people living in a south Indian urban community; a 10/66 Dementia Research Group prospective population‐based cohort study publication-title: BMC Public Health – volume: 47 start-page: 435 year: 2006 end-page: 439 article-title: The relationship of medical comorbidity and depression in older, primary care patients publication-title: Psychosomatics – volume: 30 start-page: 104 year: 2008 end-page: 109 article-title: Factors associated with depressive symptoms measured by the 12‐item General Health Questionnaire in community‐dwelling older adults (The Bambuí Health Aging Study) publication-title: Rev Bras Psiquiatr – volume: 42 start-page: 1206 year: 2003 end-page: 1252 article-title: Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure publication-title: Hypertension – volume: 16 start-page: 584 year: 2010 end-page: 596 article-title: Low grade inflammation as a common pathogenetic denominator in age‐related diseases: novel drug targets for anti‐ageing strategies and successful ageing achievement publication-title: Curr Pharm Des – volume: 5 start-page: e1000353 year: 2009 article-title: A dynamic network approach for the study of human phenotypes publication-title: PLoS Comput Biol – volume: 8 start-page: 119 year: 2008 article-title: The influence of multi‐morbidity and self‐reported socio‐economic standing on the prevalence of depression in an elderly Hong Kong population publication-title: BMC Public Health – volume: 10 start-page: 283 year: 2002 end-page: 291 article-title: Sex differences in the relationship between subthreshold depression and mortality in a community sample of older adults publication-title: Am J Geriatr Psychiatry – volume: 307 start-page: 1033 year: 2012 end-page: 1034 article-title: Preventing depression: a global priority publication-title: JAMA – volume: 6 start-page: e17837 year: 2011 article-title: Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress–preliminary findings publication-title: PLoS One – volume: 12 start-page: 216 year: 2011 end-page: 222 article-title: Platelet GSK3B activity in patients with late‐life depression: marker of depressive episode severity and cognitive impairment publication-title: World J Biol Psychiatry – volume: 18 start-page: 493 year: 2006 end-page: 503 article-title: Is the GDS‐30 better than the GHQ‐12 for screening depression in elderly people in the community? The Bambui Health Aging Study (BHAS) publication-title: Int Psychogeriatr – volume: 66 start-page: 524 year: 2008 end-page: 528 article-title: Norms for the mini‐mental state examination: adjustment of the cut‐off point in population‐based studies (evidences from the Bambuí health aging study) publication-title: Arq Neuropsiquiatr – volume: 90 start-page: 9 year: 2011 end-page: 17 article-title: Ischaemic heart disease in women: are there sex differences in pathophysiology and risk factors? Position paper from the working group on coronary pathophysiology and microcirculation of the European Society of Cardiology publication-title: Cardiovascular Res – volume: 192 start-page: 12 year: 2008 end-page: 18 article-title: Late‐life depression and mortality: influence of gender and antidepressant use publication-title: Br J Psychiatry – volume: 66 start-page: 127 year: 2009 end-page: 135 article-title: Role of depressive symptoms and comorbid chronic disease on health‐related quality of life among community‐dwelling older adults publication-title: J Psychosom Res – volume: 102 start-page: 234 year: 2003 end-page: 239 article-title: Association between depressive symptoms and twelve‐year mortality among elderly in a rural community in Taiwan publication-title: J Formos Med Assoc – volume: 5 start-page: e11266 year: 2010 article-title: Depression, antidepressant use and mortality in later life: the Health In Men Study publication-title: PLoS One – volume: 61 start-page: 587 year: 2004 end-page: 595 article-title: The nature and determinants of neuropsychological functioning in late‐life depression publication-title: Arch Gen Psychiatry – volume: 26 start-page: S5 issue: Suppl 1 year: 2003 end-page: S20 article-title: Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes mellitus publication-title: Diabetes Care – volume: 149 start-page: 116 year: 1999 end-page: 126 article-title: Psychological disorder and mortality in French older adults: do social relations modify the association publication-title: Am J Epidemiol – volume: 150 start-page: 63 issue: 1 year: 2013 end-page: 69 article-title: Depression, non‐fatal stroke and all‐cause mortality in old age: A prospective cohort study of primary care patients publication-title: J Affect Disord – volume: 44 start-page: 917 year: 2010 end-page: 920 article-title: Increased soluble TNF receptor 2 in antidepressant‐free patients with late‐life depression publication-title: J Psychiatr Res – volume: 33 start-page: 123 year: 2012 end-page: 135 article-title: Early intervention to reduce the global health and economic burden of major depression in older adults publication-title: Annu Rev Public Health – volume: 66 start-page: 459 year: 2011 end-page: 466 article-title: The association between depressive symptoms and mortality among Chinese elderly: a Hong Kong cohort study publication-title: J Gerontol A Biol Sci Med Sci. – volume: 10 start-page: 54 year: 1999 end-page: 59 article-title: Depressive symptoms and 6‐year mortality among elderly community‐dwelling women publication-title: Epidemiology – volume: 202 start-page: 22 year: 2013 end-page: 27 article-title: Differential mortality rates in major and subthreshold depression: meta‐analysis of studies that measured both publication-title: Br J Psychiatry – volume: 40 start-page: 862 year: 2011 end-page: 867 article-title: Cohort profile: the Bambui (Brazil) Cohort Study of Ageing publication-title: Int J Epidemiol – volume: 177 start-page: 336 year: 2000 end-page: 342 article-title: Association of depression and gender with mortality in old age. Results from the Amsterdam Study of the Elderly (AMSTEL) publication-title: Br J Psychiatry – volume: 346 start-page: f2570 year: 2013 article-title: Long term effect of depression care management on mortality in older adults: follow‐up of cluster randomized clinical trial in primary care publication-title: BMJ – volume: 8 start-page: e63347 year: 2013 article-title: Sex differences in age‐related cardiovascular mortality publication-title: PLoS One – volume: 56 start-page: 889 year: 1999 end-page: 895 article-title: Minor and major depression and the risk of death in older persons publication-title: Arch Gen Psychiatry – volume: 3 start-page: 237 year: 2012 article-title: Age‐by‐disease biological interactions: implications for late‐life depression publication-title: Front Genet – volume: 34 start-page: 249 year: 2012 end-page: 260 article-title: Lifetime Prevalence, age and gender distribution and age‐of‐onset of psychiatric disorders in the Sao Paulo Metropolitan Area, Brazil: results from the Sao Paulo Megacity Mental Health Survey publication-title: Rev Bras Psiquiatr – volume: 161 start-page: 59 year: 2008 end-page: 66 article-title: Increased plasma levels of 8‐iso‐PGF2alpha and IL‐6 in an elderly population with depression publication-title: Psychiatry Res – volume: 143 start-page: 35 year: 2010 end-page: 42 article-title: Low grade inflammation as measured by levels of YKL‐40: association with an increased overall and cardiovascular mortality rate in an elderly population publication-title: Int J Cardiol – reference: 12833186 - J Formos Med Assoc. 2003 Apr;102(4):234-9 – reference: 19822172 - Neurosci Biobehav Rev. 2010 Sep;35(1):2-16 – reference: 14656957 - Hypertension. 2003 Dec;42(6):1206-52 – reference: 23637108 - Br J Psychiatry. 2013 May;202(5):329-35 – reference: 23429770 - Rev Bras Psiquiatr. 2012 Oct;34(3):249-60 – reference: 21106705 - J Gerontol A Biol Sci Med Sci. 2011 Apr;66(4):459-66 – reference: 11994215 - Am J Geriatr Psychiatry. 2002 May-Jun;10(3):283-91 – reference: 19360091 - PLoS Comput Biol. 2009 Apr;5(4):e1000353 – reference: 16478572 - Int Psychogeriatr. 2006 Sep;18(3):493-503 – reference: 16959933 - Psychosomatics. 2006 Sep-Oct;47(5):435-9 – reference: 16554382 - Psychosom Med. 2006 Mar-Apr;68(2):187-200 – reference: 22429161 - Annu Rev Public Health. 2012 Apr;33:123-35 – reference: 23570892 - Am J Geriatr Psychiatry. 2013 May;21(5):493-6 – reference: 23284149 - Br J Psychiatry. 2013 Jan;202(1):22-7 – reference: 20585644 - PLoS One. 2010;5(6):e11266 – reference: 19154855 - J Psychosom Res. 2009 Feb;66(2):127-35 – reference: 23256908 - Int Psychogeriatr. 2013 Apr;25(4):677-84 – reference: 10530630 - Arch Gen Psychiatry. 1999 Oct;56(10):889-95 – reference: 23246363 - J Affect Disord. 2013 May;147(1-3):355-64 – reference: 20805109 - Int J Epidemiol. 2011 Aug;40(4):862-7 – reference: 5420206 - Br Med J. 1970 May 23;1(5707):439-43 – reference: 21878157 - Can J Psychiatry. 2011 Aug;56(8):466-73 – reference: 20439830 - Arch Gen Psychiatry. 2010 May;67(5):489-96 – reference: 10881147 - Rev Saude Publica. 2000 Apr;34(2):126-35 – reference: 9921956 - Am J Epidemiol. 1999 Jan 15;149(2):116-26 – reference: 16860269 - Gend Med. 2006 Jun;3(2):93-109 – reference: 19223085 - Int J Cardiol. 2010 Aug 6;143(1):35-42 – reference: 18410677 - BMC Public Health. 2008;8:119 – reference: 21159671 - Cardiovasc Res. 2011 Apr 1;90(1):9-17 – reference: 18470408 - Rev Bras Psiquiatr. 2008 Jun;30(2):104-9 – reference: 18783834 - Psychiatry Res. 2008 Oct 30;161(1):59-66 – reference: 9888280 - Epidemiology. 1999 Jan;10(1):54-9 – reference: 23738992 - BMJ. 2013;346:f2570 – reference: 12540353 - Age Ageing. 2003 Jan;32(1):81-7 – reference: 17545451 - Am J Geriatr Psychiatry. 2007 Jun;15(6):522-9 – reference: 22633396 - J Psychiatr Res. 2012 Aug;46(8):1081-5 – reference: 15184238 - Arch Gen Psychiatry. 2004 Jun;61(6):587-95 – reference: 23162569 - Front Genet. 2012 Nov 16;3:237 – reference: 21314327 - World J Biol Psychiatry. 2011 Apr;12(3):216-22 – reference: 22416097 - JAMA. 2012 Mar 14;307(10):1033-4 – reference: 5420677 - Gerontologist. 1970 Spring;10(1):20-30 – reference: 12502614 - Diabetes Care. 2003 Jan;26 Suppl 1:S5-20 – reference: 20388068 - Curr Pharm Des. 2010;16(6):584-96 – reference: 20808123 - Am J Geriatr Psychiatry. 2011 Feb;19(2):142-50 – reference: 23474092 - J Affect Disord. 2013 Aug 15;150(1):63-9 – reference: 20573243 - BMC Public Health. 2010;10:366 – reference: 18174502 - Br J Psychiatry. 2008 Jan;192(1):12-8 – reference: 20338581 - J Psychiatr Res. 2010 Oct;44(14):917-20 – reference: 18813712 - Arq Neuropsiquiatr. 2008 Sep;66(3A):524-8 – reference: 11116775 - Br J Psychiatry. 2000 Oct;177:336-42 – reference: 23700418 - PLoS One. 2013;8(5):e63347 – reference: 21448457 - PLoS One. 2011;6(3):e17837 – reference: 23266538 - JAMA Psychiatry. 2013 Feb;70(2):176-84 |
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Increased mortality risk and its moderators is an important, but still under recognized, negative outcome of late‐life depression (LLD). Therefore,... Increased mortality risk and its moderators is an important, but still under recognized, negative outcome of late-life depression (LLD). Therefore, we aimed to... Background Increased mortality risk and its moderators is an important, but still under recognized, negative outcome of late-life depression (LLD). Therefore,... |
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| SubjectTerms | Age Factors Aged Aged, 80 and over Aging Brazil - epidemiology Cohort Studies cohort study Depression - epidemiology Depression - mortality Female Humans late-life depression Male Middle Aged mortality risk factor Risk Factors Severity of Illness Index Sex Factors |
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| Title | THE EFFECT OF GENDER, AGE, AND SYMPTOM SEVERITY IN LATE-LIFE DEPRESSION ON THE RISK OF ALL-CAUSE MORTALITY: THE BAMBUÍ COHORT STUDY OF AGING |
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