Differences in the Personality Profile of Medication-Overuse Headache Sufferers and Drug Addict Patients: A Comparative Study Using MMPI-2
(Headache 2011;51:1212‐1227) Background.— Medication‐overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of personality needs studies to explain the shifting from drug use to drug abuse. The main aim of this study is to study personality, according to...
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| Published in | Headache Vol. 51; no. 8; pp. 1212 - 1227 |
|---|---|
| Main Authors | , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Malden, USA
Blackwell Publishing Inc
01.09.2011
Wiley-Blackwell Wiley Subscription Services, Inc |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0017-8748 1526-4610 1526-4610 |
| DOI | 10.1111/j.1526-4610.2011.01978.x |
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| Abstract | (Headache 2011;51:1212‐1227)
Background.— Medication‐overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of personality needs studies to explain the shifting from drug use to drug abuse. The main aim of this study is to study personality, according to Minnesota Multiphasic Personality Inventory, comparing MOH, episodic headache, substance addicts (SA) vs healthy controls.
Methods.— Eighty‐two MOH patients (mean age 44.5; 20 M, 62 F) and 35 episodic headache (mean age 40.2; 8 M, 27 F), were compared to 37 SA (mean age 32.5; 29 M, 8 F) and 37 healthy controls (mean age: 32.49; 20 M, 17 F). International Classification of Headache Disorders 2nd Edition criteria were employed. Chi‐square test, Kruskal‐Wallis test, and post hoc comparisons were used for statistics.
Results.— MOH patients scored higher on Hypochondriasis, Depression (only females), Hysteria (only females) (P < .000). MOH did not show higher scores than episodic headache or healthy controls in dependency scales, while SA did.
Conclusion.— The data obtained show that MOH and SA do not share common personality characteristics linked to dependence. Although further studies are needed to understand if such a difference is related to instrumental characteristics or to yet undiscovered psychobiological characteristics of MOH patients; however, we hypothesize that the detected difference may rely on the fact that drug dependence in the 2 groups is promoted by entirely different needs: pleasure seeking in the SA group, pain avoidance in the MOH group. |
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| AbstractList | (Headache 2011;51:1212‐1227)
Background.— Medication‐overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of personality needs studies to explain the shifting from drug use to drug abuse. The main aim of this study is to study personality, according to Minnesota Multiphasic Personality Inventory, comparing MOH, episodic headache, substance addicts (SA) vs healthy controls.
Methods.— Eighty‐two MOH patients (mean age 44.5; 20 M, 62 F) and 35 episodic headache (mean age 40.2; 8 M, 27 F), were compared to 37 SA (mean age 32.5; 29 M, 8 F) and 37 healthy controls (mean age: 32.49; 20 M, 17 F). International Classification of Headache Disorders 2nd Edition criteria were employed. Chi‐square test, Kruskal‐Wallis test, and post hoc comparisons were used for statistics.
Results.— MOH patients scored higher on Hypochondriasis, Depression (only females), Hysteria (only females) (P < .000). MOH did not show higher scores than episodic headache or healthy controls in dependency scales, while SA did.
Conclusion.— The data obtained show that MOH and SA do not share common personality characteristics linked to dependence. Although further studies are needed to understand if such a difference is related to instrumental characteristics or to yet undiscovered psychobiological characteristics of MOH patients; however, we hypothesize that the detected difference may rely on the fact that drug dependence in the 2 groups is promoted by entirely different needs: pleasure seeking in the SA group, pain avoidance in the MOH group. Medication-overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of personality needs studies to explain the shifting from drug use to drug abuse. The main aim of this study is to study personality, according to Minnesota Multiphasic Personality Inventory, comparing MOH, episodic headache, substance addicts (SA) vs healthy controls. Eighty-two MOH patients (mean age 44.5; 20 M, 62 F) and 35 episodic headache (mean age 40.2; 8 M, 27 F), were compared to 37 SA (mean age 32.5; 29 M, 8 F) and 37 healthy controls (mean age: 32.49; 20 M, 17 F). International Classification of Headache Disorders 2nd Edition criteria were employed. Chi-square test, Kruskal-Wallis test, and post hoc comparisons were used for statistics. MOH patients scored higher on Hypochondriasis, Depression (only females), Hysteria (only females) (P < .000). MOH did not show higher scores than episodic headache or healthy controls in dependency scales, while SA did. The data obtained show that MOH and SA do not share common personality characteristics linked to dependence. Although further studies are needed to understand if such a difference is related to instrumental characteristics or to yet undiscovered psychobiological characteristics of MOH patients; however, we hypothesize that the detected difference may rely on the fact that drug dependence in the 2 groups is promoted by entirely different needs: pleasure seeking in the SA group, pain avoidance in the MOH group. Background.- Medication-overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of personality needs studies to explain the shifting from drug use to drug abuse. The main aim of this study is to study personality, according to Minnesota Multiphasic Personality Inventory, comparing MOH, episodic headache, substance addicts (SA) vs healthy controls. Methods.- Eighty-two MOH patients (mean age 44.5; 20M, 62F) and 35 episodic headache (mean age 40.2; 8M, 27F), were compared to 37 SA (mean age 32.5; 29M, 8F) and 37 healthy controls (mean age: 32.49; 20M, 17F). International Classification of Headache Disorders 2nd Edition criteria were employed. Chi-square test, Kruskal-Wallis test, and post hoc comparisons were used for statistics. Conclusion.- The data obtained show that MOH and SA do not share common personality characteristics linked to dependence. Although further studies are needed to understand if such a difference is related to instrumental characteristics or to yet undiscovered psychobiological characteristics of MOH patients; however, we hypothesize that the detected difference may rely on the fact that drug dependence in the 2 groups is promoted by entirely different needs: pleasure seeking in the SA group, pain avoidance in the MOH group.Original Abstract: (Headache 2011; 51:1212-1227) Results.- MOH patients scored higher on Hypochondriasis, Depression (only females), Hysteria (only females) (P<.000). MOH did not show higher scores than episodic headache or healthy controls in dependency scales, while SA did. Medication-overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of personality needs studies to explain the shifting from drug use to drug abuse. The main aim of this study is to study personality, according to Minnesota Multiphasic Personality Inventory, comparing MOH, episodic headache, substance addicts (SA) vs healthy controls.BACKGROUNDMedication-overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of personality needs studies to explain the shifting from drug use to drug abuse. The main aim of this study is to study personality, according to Minnesota Multiphasic Personality Inventory, comparing MOH, episodic headache, substance addicts (SA) vs healthy controls.Eighty-two MOH patients (mean age 44.5; 20 M, 62 F) and 35 episodic headache (mean age 40.2; 8 M, 27 F), were compared to 37 SA (mean age 32.5; 29 M, 8 F) and 37 healthy controls (mean age: 32.49; 20 M, 17 F). International Classification of Headache Disorders 2nd Edition criteria were employed. Chi-square test, Kruskal-Wallis test, and post hoc comparisons were used for statistics.METHODSEighty-two MOH patients (mean age 44.5; 20 M, 62 F) and 35 episodic headache (mean age 40.2; 8 M, 27 F), were compared to 37 SA (mean age 32.5; 29 M, 8 F) and 37 healthy controls (mean age: 32.49; 20 M, 17 F). International Classification of Headache Disorders 2nd Edition criteria were employed. Chi-square test, Kruskal-Wallis test, and post hoc comparisons were used for statistics.MOH patients scored higher on Hypochondriasis, Depression (only females), Hysteria (only females) (P < .000). MOH did not show higher scores than episodic headache or healthy controls in dependency scales, while SA did.RESULTSMOH patients scored higher on Hypochondriasis, Depression (only females), Hysteria (only females) (P < .000). MOH did not show higher scores than episodic headache or healthy controls in dependency scales, while SA did.The data obtained show that MOH and SA do not share common personality characteristics linked to dependence. Although further studies are needed to understand if such a difference is related to instrumental characteristics or to yet undiscovered psychobiological characteristics of MOH patients; however, we hypothesize that the detected difference may rely on the fact that drug dependence in the 2 groups is promoted by entirely different needs: pleasure seeking in the SA group, pain avoidance in the MOH group.CONCLUSIONThe data obtained show that MOH and SA do not share common personality characteristics linked to dependence. Although further studies are needed to understand if such a difference is related to instrumental characteristics or to yet undiscovered psychobiological characteristics of MOH patients; however, we hypothesize that the detected difference may rely on the fact that drug dependence in the 2 groups is promoted by entirely different needs: pleasure seeking in the SA group, pain avoidance in the MOH group. (Headache 2011;51:1212-1227) Background.-- Medication-overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of personality needs studies to explain the shifting from drug use to drug abuse. The main aim of this study is to study personality, according to Minnesota Multiphasic Personality Inventory, comparing MOH, episodic headache, substance addicts (SA) vs healthy controls. Methods.-- Eighty-two MOH patients (mean age 44.5; 20 M, 62 F) and 35 episodic headache (mean age 40.2; 8 M, 27 F), were compared to 37 SA (mean age 32.5; 29 M, 8 F) and 37 healthy controls (mean age: 32.49; 20 M, 17 F). International Classification of Headache Disorders 2nd Edition criteria were employed. Chi-square test, Kruskal-Wallis test, and post hoc comparisons were used for statistics. Results.-- MOH patients scored higher on Hypochondriasis, Depression (only females), Hysteria (only females) (P < .000). MOH did not show higher scores than episodic headache or healthy controls in dependency scales, while SA did. Conclusion.-- The data obtained show that MOH and SA do not share common personality characteristics linked to dependence. Although further studies are needed to understand if such a difference is related to instrumental characteristics or to yet undiscovered psychobiological characteristics of MOH patients; however, we hypothesize that the detected difference may rely on the fact that drug dependence in the 2 groups is promoted by entirely different needs: pleasure seeking in the SA group, pain avoidance in the MOH group. [PUBLICATION ABSTRACT] |
| Author | Anastasi, Serena Guidetti, Vincenzo Sances, Grazia Pozzi, Gino Matarrese, Adriana Frustaci, Alessandra Ghiotto, Natascia Pazzi, Stefania Chirumbolo, Antonio Nappi, Giuseppe Tassorelli, Cristina Allena, Marta Galli, Federica Quartesan, Roberto |
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Pozzi); Unit of Clinical and Molecular Epidemiology - IRCCS "San Raffaele Pisana," Rome, Italy (A. Frustaci); Psychiatry Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy (S. Anastasi and R. Quartesan); Faculty of Psychology 1, Department of Social & Developmental Psychology, "Sapienza" University of Rome, Italy (A. Chirumbolo); SerT Sud-Est, ASL 10, Florence, Italy (A. Matarrese) – sequence: 5 givenname: Serena surname: Anastasi fullname: Anastasi, Serena organization: From the Department of Child and Adolescent Neurology, Psychiatry and Rehabilitation, "Sapienza" University of Rome, Italy (F. Galli and V. Guidetti); Headache Science Centre, National Neurological Institute C. Mondino Foundation and Consortium for Adaptive Disorders and Head-pain (UCADH), University of Pavia, Italy (F. Galli, M. Allena, N. Ghiotto, G. Nappi, S. Pazzi, G. Sances, and C. Tassorelli); Institute of Psychiatry and Psychology, Università Cattolica del Sacro Cuore, Rome, Italy (G. Pozzi); Unit of Clinical and Molecular Epidemiology - IRCCS "San Raffaele Pisana," Rome, Italy (A. Frustaci); Psychiatry Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy (S. Anastasi and R. Quartesan); Faculty of Psychology 1, Department of Social & Developmental Psychology, "Sapienza" University of Rome, Italy (A. Chirumbolo); SerT Sud-Est, ASL 10, Florence, Italy (A. Matarrese) – sequence: 6 givenname: Antonio surname: Chirumbolo fullname: Chirumbolo, Antonio organization: From the Department of Child and Adolescent Neurology, Psychiatry and Rehabilitation, "Sapienza" University of Rome, Italy (F. Galli and V. Guidetti); Headache Science Centre, National Neurological Institute C. Mondino Foundation and Consortium for Adaptive Disorders and Head-pain (UCADH), University of Pavia, Italy (F. Galli, M. Allena, N. Ghiotto, G. Nappi, S. 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Guidetti); Headache Science Centre, National Neurological Institute C. Mondino Foundation and Consortium for Adaptive Disorders and Head-pain (UCADH), University of Pavia, Italy (F. Galli, M. Allena, N. Ghiotto, G. Nappi, S. Pazzi, G. Sances, and C. Tassorelli); Institute of Psychiatry and Psychology, Università Cattolica del Sacro Cuore, Rome, Italy (G. Pozzi); Unit of Clinical and Molecular Epidemiology - IRCCS "San Raffaele Pisana," Rome, Italy (A. Frustaci); Psychiatry Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy (S. Anastasi and R. Quartesan); Faculty of Psychology 1, Department of Social & Developmental Psychology, "Sapienza" University of Rome, Italy (A. Chirumbolo); SerT Sud-Est, ASL 10, Florence, Italy (A. Matarrese) – sequence: 11 givenname: Stefania surname: Pazzi fullname: Pazzi, Stefania organization: From the Department of Child and Adolescent Neurology, Psychiatry and Rehabilitation, "Sapienza" University of Rome, Italy (F. Galli and V. Guidetti); Headache Science Centre, National Neurological Institute C. Mondino Foundation and Consortium for Adaptive Disorders and Head-pain (UCADH), University of Pavia, Italy (F. Galli, M. Allena, N. Ghiotto, G. Nappi, S. Pazzi, G. Sances, and C. Tassorelli); Institute of Psychiatry and Psychology, Università Cattolica del Sacro Cuore, Rome, Italy (G. Pozzi); Unit of Clinical and Molecular Epidemiology - IRCCS "San Raffaele Pisana," Rome, Italy (A. Frustaci); Psychiatry Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy (S. Anastasi and R. Quartesan); Faculty of Psychology 1, Department of Social & Developmental Psychology, "Sapienza" University of Rome, Italy (A. Chirumbolo); SerT Sud-Est, ASL 10, Florence, Italy (A. Matarrese) – sequence: 12 givenname: Roberto surname: Quartesan fullname: Quartesan, Roberto organization: From the Department of Child and Adolescent Neurology, Psychiatry and Rehabilitation, "Sapienza" University of Rome, Italy (F. Galli and V. Guidetti); Headache Science Centre, National Neurological Institute C. Mondino Foundation and Consortium for Adaptive Disorders and Head-pain (UCADH), University of Pavia, Italy (F. Galli, M. Allena, N. Ghiotto, G. Nappi, S. Pazzi, G. Sances, and C. Tassorelli); Institute of Psychiatry and Psychology, Università Cattolica del Sacro Cuore, Rome, Italy (G. Pozzi); Unit of Clinical and Molecular Epidemiology - IRCCS "San Raffaele Pisana," Rome, Italy (A. Frustaci); Psychiatry Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy (S. Anastasi and R. Quartesan); Faculty of Psychology 1, Department of Social & Developmental Psychology, "Sapienza" University of Rome, Italy (A. Chirumbolo); SerT Sud-Est, ASL 10, Florence, Italy (A. Matarrese) – sequence: 13 givenname: Grazia surname: Sances fullname: Sances, Grazia organization: From the Department of Child and Adolescent Neurology, Psychiatry and Rehabilitation, "Sapienza" University of Rome, Italy (F. Galli and V. Guidetti); Headache Science Centre, National Neurological Institute C. Mondino Foundation and Consortium for Adaptive Disorders and Head-pain (UCADH), University of Pavia, Italy (F. Galli, M. Allena, N. Ghiotto, G. Nappi, S. Pazzi, G. Sances, and C. Tassorelli); Institute of Psychiatry and Psychology, Università Cattolica del Sacro Cuore, Rome, Italy (G. Pozzi); Unit of Clinical and Molecular Epidemiology - IRCCS "San Raffaele Pisana," Rome, Italy (A. Frustaci); Psychiatry Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy (S. Anastasi and R. Quartesan); Faculty of Psychology 1, Department of Social & Developmental Psychology, "Sapienza" University of Rome, Italy (A. Chirumbolo); SerT Sud-Est, ASL 10, Florence, Italy (A. Matarrese) – sequence: 14 givenname: Cristina surname: Tassorelli fullname: Tassorelli, Cristina organization: From the Department of Child and Adolescent Neurology, Psychiatry and Rehabilitation, "Sapienza" University of Rome, Italy (F. Galli and V. Guidetti); Headache Science Centre, National Neurological Institute C. Mondino Foundation and Consortium for Adaptive Disorders and Head-pain (UCADH), University of Pavia, Italy (F. Galli, M. Allena, N. Ghiotto, G. Nappi, S. Pazzi, G. Sances, and C. Tassorelli); Institute of Psychiatry and Psychology, Università Cattolica del Sacro Cuore, Rome, Italy (G. Pozzi); Unit of Clinical and Molecular Epidemiology - IRCCS "San Raffaele Pisana," Rome, Italy (A. Frustaci); Psychiatry Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy (S. Anastasi and R. Quartesan); Faculty of Psychology 1, Department of Social & Developmental Psychology, "Sapienza" University of Rome, Italy (A. Chirumbolo); SerT Sud-Est, ASL 10, Florence, Italy (A. Matarrese) |
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| ISSN | 0017-8748 1526-4610 |
| IngestDate | Thu Jul 10 17:17:51 EDT 2025 Fri Jul 11 05:55:19 EDT 2025 Fri Jul 25 19:56:13 EDT 2025 Mon Jul 21 06:03:06 EDT 2025 Mon Jul 21 09:14:18 EDT 2025 Wed Jan 22 16:31:36 EST 2025 Sun Sep 21 06:16:38 EDT 2025 |
| IsPeerReviewed | true |
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| Issue | 8 |
| Keywords | Human Headache Drug addiction Nervous system diseases medication-overuse headache Cerebral disorder Chemotherapy Treatment Pain Addiction personality Central nervous system disease Dependence MMPI-2 Neurological disorder Comparative study Cerebrovascular disease |
| Language | English |
| License | CC BY 4.0 2011 American Headache Society. |
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| Notes | ark:/67375/WNG-7FQLGDT2-G istex:D39C1A134EAFFAD5C27E5B0FECE84F82CAF6C080 ArticleID:HEAD1978 Funding Source: None None Conflict of Interest ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Article-2 ObjectType-Feature-1 content type line 23 |
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| PublicationCentury | 2000 |
| PublicationDate | September 2011 |
| PublicationDateYYYYMMDD | 2011-09-01 |
| PublicationDate_xml | – month: 09 year: 2011 text: September 2011 |
| PublicationDecade | 2010 |
| PublicationPlace | Malden, USA |
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| PublicationTitle | Headache |
| PublicationTitleAlternate | Headache |
| PublicationYear | 2011 |
| Publisher | Blackwell Publishing Inc Wiley-Blackwell Wiley Subscription Services, Inc |
| Publisher_xml | – name: Blackwell Publishing Inc – name: Wiley-Blackwell – name: Wiley Subscription Services, Inc |
| References | American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). International Version with ICD-10 codes. Washington, DC: American Psychiatric Association; 1994. Pascual J, Colás R, Castillo J. Epidemiology of chronic daily headache. Curr Pain Headache Rep. 2001;5:529-536. Fuh JL, Wang SJ, Lu SR, Juang KD. Does medication overuse headache represent a behavior of dependence? Pain. 2005;119:49-55. Serretti A, Calati R, Giegling I, et al. 5-HT2A SNPs and the Temperament and Character Inventory. Prog Neuropsychopharmacol Biol Psychiatry. 2007;31:1275-1281. Bigal ME, Sheftell FD, Rapaport AM, Tepper SJ, Weeks R, Baskin SM. MMPI personality profiles in patients with primary chronic headache: A case-control study. Neurol Sci. 2003;24:103-110. Schnider P, Aull S, Baumgartner C, et al. Long-term outcome of patients with headache and drug abuse after inpatient withdrawal: Five-year follow-up. Cephalalgia. 1996;16:481-485. Radat F, Irachabal S, Swendsen J, Henry P. Analgesic abuse and psychiatric comorbidity in headache patients. Encephale. 2002;28:466-471. Katsarava Z, Muessig M, Dzagnizde A, Fritsche G, Diener HC, Limmroth V. Medication overuse headache: Rates and predictors for relapse in a 4-year prospective study. Cephalalgia. 2004;25:12-15. Radat F, Sakh D, Lutz G, el Amrani M, Ferreri M, Bousser MG. Psychiatric comorbidity is related to headache induced by chronic substance use in migraineurs. Headache. 1999;39:477-480. Cloninger CR. The Temperament and Character Inventory - Revised. St. Louis, MO: Center for Psychobiology of Personality, Washington University; 1999. Ferrari A, Cicero AF, Bertolini A, Leone S, Pasciullo G, Sternieri E. Need for analgesics/drugs of abuse: A comparison between headache patients and addicts by the Leeds Dependence Questionnaire (LDQ). Cephalalgia. 2006;26:187-193. Rossi P, Jensen R, Nappi G, Allena M, COMOESTAS Consortium. A narrative review on the management of medication overuse headache: The steep road from experience to evidence. J Headache Pain. 2009;10:407-417. Ghiotto N, Sances G, Galli F, et al. Medication-overuse headache and applicability of the ICHD-II diagnostic criteria: One-year follow-up study (CARE I protocol). Cephalalgia. 2008;29:233-243. Elkind AH. Drug abuse and headache. Med Clin North Am. 1991;75:717-732. Aronoff GM. Opioids in chronic pain management: Is there a significant risk of addiction? Curr Rev Pain. 2000;4:112-121. Grazzi L, Andrasik F, D'Amico D, et al. Behavioral and pharmacologic treatment of transformed migraine with analgesic overuse: Outcome at 3 years. Headache. 2002;59:1011-1114. Weybrew BB. MMPI patterns of physically and psychologically dependent drug abusers. Percept Mot Skills. 1996;83:640-642. Headache Classification Committee, Olesen J, Bousser MG, Diener HC, et al. New appendix criteria open for a broader concept of chronic migraine. Cephalalgia. 2006;26:742-746. Bigal ME, Rapoport AM, Sheftell FD, Tepper SJ, Lipton RB. Transformed migraine and medication overuse in a tertiary headache centre - clinical characteristics and treatment outcomes. Cephalalgia. 2004;24:483-490. Adams EH, Breiner S, Cicero TJ, Geller A, Inciardi JA, Schnoll SH. A comparison of the abuse liability of tramadol, NSAIDs and hydrocodone in patients with chronic pain. J Pain Symptom Manage. 2006;31:465-476. Mongini F, Rota E, Deregibus A, Mura F, Francia Germani A, Mongini T. A comparative analysis of personality profile and muscle tenderness between chronic migraine and chronic tension-type headache. Neurol Sci. 2005;26:203-207. Clements R, Heintz JM. Diagnostic accuracy and factor structure of the AAS and APS scales of the MMPI-2. J Pers Assess. 2002;79:564-582. Svanum S, McGrew J, Ehrmann L. Validity of the substance abuse scales of the MMPI-2 in a college student sample. J Pers Assess. 1994;62:427-439. Atasoy HT, Atasoy N, Unal AE, Emre U, Sumer M. Psychiatric comorbidity in medication overuse headache patients with pre-existing headache type of episodic tension-type headache. Eur J Pain. 2005;9:285-291. Calabresi P, Cupini LM. Medication-overuse headache: Similarities with drug addiction. Trends Pharmacol Sci. 2005;26:62-68. Rapoport A, Stang P, Gutterman DL, et al. Analgesic rebound headache in clinical practice: Data from a physician survey. Headache. 1996;36:14-19. Weed NC, Butcher JN, McKenna T, Ben-Porath YS. New measures for assessing alcohol and drug abuse with the MMPI-2: The APS and AAS. J Pers Assess. 1992;58:389-404. Janiri L, Martinotti G, Dario T, Schifano F, Bria P. The gamblers' Temperament and Character Inventory (TCI) personality profile. Subst Use Misuse. 2007;42:975-984. Sbrana A, Bizzarri JV, Rucci P, et al. The spectrum of substance use in mood and anxiety disorders. Compr Psychiatry. 2005;46:6-13. Huber D, Henrich G. Personality traits and stress sensitivity in migraine patients. Behav Med. 2003;29:4-13. Papageorgiou C, Rabavilas A, Liappas I, Stefanis C. Do obsessive-compulsive patients and abstinent heroin addicts share a common psychophysiological mechanism? Neuropsychobiology. 2003;47:1-11. Sheftell FD, Atlas SJ. Migraine and psychiatric comorbidity: From theory and hypotheses to clinical application. Headache. 2002;42:934-944. Fritsche G, Eberl A, Katsarava Z, Limmoroth V, Diener HC. Drug-induced headache: Long-term follow up of withdrawal therapy and persistence of drug misuse. Eur Neurol. 2001;45:229-235. Weissman DE, Haddox JD. Opioid pseudoaddiction - an iatrogenic syndrome. Pain. 1989;36:363-366. Mongini F, Ibertis F, Barbalonga E, Raviola F. MMPI-2 profiles in chronic daily headache and their relationship to anxiety levels and accompanying symptoms. Headache. 2000;40:466-472. Ferrari A, Leone S, Tacchi R, et al. The link between pain patient and analgesic medication is greater in migraine than in rheumatic disease patients. Cephalalgia. 2009;29:31-37. Limmroth V, Katsarava Z, Fritsche G, Przywara S, Diener HC. Features of medication overuse headache following overuse of different acute headache drugs. Neurology. 2002;59:1011-1014. Greene RL, Weed NC, Butcher JN, Arredondo R, Davis HG. A cross-validation of MMPI-2 substance abuse scales. J Pers Assess. 1992;58:405-410. Arena JG, Blanchard EB, Andrasik F, Applebaum K. Obsessions and compulsions in three kinds of headache sufferers: Analysis of the Maudsley Questionnaire. Behav Res Ther. 1986;24:127-132. Galli F, Patron L, Russo PM, Bruni O, Ferini-Strambi L, Guidetti V. Chronic daily headache in childhood and adolescence: Clinical aspects and a 4-year follow-up. Cephalalgia. 2004;24:850-858. Pancheri P, Sirigatti S. MMPI-2 (Italian Version). Firenze: Organizzazioni Speciali; 1995. Butcher JN, Dahlstrom WG, Graham JR, Tellegen A. MMPI-2. Minneapolis, MN: Minnesota University Press; 1989. Compton P, Darakjian J, Miotto K. Screening for addiction in patients with chronic pain and "problematic" substance use: Evaluation of a pilot assessment tool. J Pain Symptom Manage. 1998;16:355-363. Vendrig AA. The MMPI and chronic pain: A conceptual analysis of a long-standing but complicated relationship. Clin Psychol Rev. 2000;20:533-559. Radat F, Creac'h C, Guegan-Massardier E, et al. Behavioral dependence in patients with medication overuse headache: A cross-sectional study in consulting patients using the DSM-IV criteria. Headache. 2008;48:1026-1036. Pancratz L, Hickman DH, Toth S. The identification and management of drug-seeking behaviour in a medical center. Drug Alcohol Depend. 1989;24:115-118. Katsarava Z, Jensen R. Medication-overuse headache: Where are we now? Curr Opin Neurol. 2007;20:326-330. Cupini LM, Costa C, Sarchielli P, et al. Degradation of endocannabinoids in chronic migraine and medication overuse headache. Neurobiol Dis. 2008;30:186-189. Headache Classification Subcommittee of the International Headache Society. The International Classification of Headache Disorders-2nd edition. Cephalalgia. 2004;24(Suppl. 1):9-160. Ladd JS. MMPI-2 critical item norms in chemically dependent inpatients. J Clin Psychol. 1996;52:367-372. Mongini F, Keller R, Deregibus A, Raviola F, Mongini T, Sancarlo M. Personality traits, depression and migraine in women: A longitudinal study. Cephalalgia. 2003;23:186-192. Fumal A, Laureys S, Di Clemente L, et al. Orbitofrontal cortex involvement in chronic analgesic-overuse headache evolving from episodic migraine. Brain. 2006;129:543-550. Saper JR, Hamel RL, Lake AE 3rd. Medication overuse headache (MOH) is a biobehavioural disorder. Cephalalgia. 2005;25:545-546. Guidetti V, Galli F, Fabrizi P, et al. Headache and psychiatric comorbidity: Clinical aspects and outcome in an 8-year follow-up study. Cephalalgia. 1998;18:455-462. Luconi R, Bartolini M, Taffi R, et al. Prognostic significance of personality profiles in patients with chronic migraine. Headache. 2007;47:1118-1124. 2002; 59 2006; 31 2000; 4 2004; 25 2004; 24 1992; 58 2008; 30 1996; 36 2005; 26 2007; 31 2001; 45 1994; 62 2005; 25 1998; 16 1998; 18 2009; 10 2002; 42 2008; 29 2006; 26 2003; 47 2007; 20 2006; 129 1989; 36 1989 2010 2002; 79 1991; 75 2000; 20 2005; 119 1996; 52 1995 1994 1996; 16 1989; 24 2009; 29 2005; 46 1999 2002; 28 2001; 5 2005; 9 1999; 39 1986; 24 2003; 24 1996; 83 2008; 48 2000; 40 2003; 29 1994; 1 2007; 42 2007; 47 2003; 23 |
| References_xml | – reference: Radat F, Irachabal S, Swendsen J, Henry P. Analgesic abuse and psychiatric comorbidity in headache patients. Encephale. 2002;28:466-471. – reference: Greene RL, Weed NC, Butcher JN, Arredondo R, Davis HG. A cross-validation of MMPI-2 substance abuse scales. J Pers Assess. 1992;58:405-410. – reference: Papageorgiou C, Rabavilas A, Liappas I, Stefanis C. Do obsessive-compulsive patients and abstinent heroin addicts share a common psychophysiological mechanism? Neuropsychobiology. 2003;47:1-11. – reference: Fritsche G, Eberl A, Katsarava Z, Limmoroth V, Diener HC. Drug-induced headache: Long-term follow up of withdrawal therapy and persistence of drug misuse. Eur Neurol. 2001;45:229-235. – reference: Ladd JS. MMPI-2 critical item norms in chemically dependent inpatients. J Clin Psychol. 1996;52:367-372. – reference: Cupini LM, Costa C, Sarchielli P, et al. Degradation of endocannabinoids in chronic migraine and medication overuse headache. Neurobiol Dis. 2008;30:186-189. – reference: Fuh JL, Wang SJ, Lu SR, Juang KD. Does medication overuse headache represent a behavior of dependence? Pain. 2005;119:49-55. – reference: Svanum S, McGrew J, Ehrmann L. Validity of the substance abuse scales of the MMPI-2 in a college student sample. J Pers Assess. 1994;62:427-439. – reference: Pancratz L, Hickman DH, Toth S. The identification and management of drug-seeking behaviour in a medical center. Drug Alcohol Depend. 1989;24:115-118. – reference: Calabresi P, Cupini LM. Medication-overuse headache: Similarities with drug addiction. Trends Pharmacol Sci. 2005;26:62-68. – reference: Limmroth V, Katsarava Z, Fritsche G, Przywara S, Diener HC. Features of medication overuse headache following overuse of different acute headache drugs. Neurology. 2002;59:1011-1014. – reference: Schnider P, Aull S, Baumgartner C, et al. Long-term outcome of patients with headache and drug abuse after inpatient withdrawal: Five-year follow-up. Cephalalgia. 1996;16:481-485. – reference: Bigal ME, Rapoport AM, Sheftell FD, Tepper SJ, Lipton RB. Transformed migraine and medication overuse in a tertiary headache centre - clinical characteristics and treatment outcomes. Cephalalgia. 2004;24:483-490. – reference: Luconi R, Bartolini M, Taffi R, et al. Prognostic significance of personality profiles in patients with chronic migraine. Headache. 2007;47:1118-1124. – reference: Saper JR, Hamel RL, Lake AE 3rd. Medication overuse headache (MOH) is a biobehavioural disorder. Cephalalgia. 2005;25:545-546. – reference: Sheftell FD, Atlas SJ. Migraine and psychiatric comorbidity: From theory and hypotheses to clinical application. Headache. 2002;42:934-944. – reference: Janiri L, Martinotti G, Dario T, Schifano F, Bria P. The gamblers' Temperament and Character Inventory (TCI) personality profile. Subst Use Misuse. 2007;42:975-984. – reference: Huber D, Henrich G. Personality traits and stress sensitivity in migraine patients. Behav Med. 2003;29:4-13. – reference: Elkind AH. Drug abuse and headache. Med Clin North Am. 1991;75:717-732. – reference: Ghiotto N, Sances G, Galli F, et al. Medication-overuse headache and applicability of the ICHD-II diagnostic criteria: One-year follow-up study (CARE I protocol). Cephalalgia. 2008;29:233-243. – reference: Adams EH, Breiner S, Cicero TJ, Geller A, Inciardi JA, Schnoll SH. A comparison of the abuse liability of tramadol, NSAIDs and hydrocodone in patients with chronic pain. J Pain Symptom Manage. 2006;31:465-476. – reference: Katsarava Z, Jensen R. Medication-overuse headache: Where are we now? Curr Opin Neurol. 2007;20:326-330. – reference: Headache Classification Committee, Olesen J, Bousser MG, Diener HC, et al. New appendix criteria open for a broader concept of chronic migraine. Cephalalgia. 2006;26:742-746. – reference: Guidetti V, Galli F, Fabrizi P, et al. Headache and psychiatric comorbidity: Clinical aspects and outcome in an 8-year follow-up study. Cephalalgia. 1998;18:455-462. – reference: Ferrari A, Cicero AF, Bertolini A, Leone S, Pasciullo G, Sternieri E. Need for analgesics/drugs of abuse: A comparison between headache patients and addicts by the Leeds Dependence Questionnaire (LDQ). Cephalalgia. 2006;26:187-193. – reference: Weybrew BB. MMPI patterns of physically and psychologically dependent drug abusers. Percept Mot Skills. 1996;83:640-642. – reference: Arena JG, Blanchard EB, Andrasik F, Applebaum K. Obsessions and compulsions in three kinds of headache sufferers: Analysis of the Maudsley Questionnaire. Behav Res Ther. 1986;24:127-132. – reference: Katsarava Z, Muessig M, Dzagnizde A, Fritsche G, Diener HC, Limmroth V. Medication overuse headache: Rates and predictors for relapse in a 4-year prospective study. Cephalalgia. 2004;25:12-15. – reference: Bigal ME, Sheftell FD, Rapaport AM, Tepper SJ, Weeks R, Baskin SM. MMPI personality profiles in patients with primary chronic headache: A case-control study. Neurol Sci. 2003;24:103-110. – reference: Mongini F, Keller R, Deregibus A, Raviola F, Mongini T, Sancarlo M. Personality traits, depression and migraine in women: A longitudinal study. Cephalalgia. 2003;23:186-192. – reference: Sbrana A, Bizzarri JV, Rucci P, et al. The spectrum of substance use in mood and anxiety disorders. Compr Psychiatry. 2005;46:6-13. – reference: Vendrig AA. The MMPI and chronic pain: A conceptual analysis of a long-standing but complicated relationship. Clin Psychol Rev. 2000;20:533-559. – reference: Rapoport A, Stang P, Gutterman DL, et al. Analgesic rebound headache in clinical practice: Data from a physician survey. Headache. 1996;36:14-19. – reference: Galli F, Patron L, Russo PM, Bruni O, Ferini-Strambi L, Guidetti V. Chronic daily headache in childhood and adolescence: Clinical aspects and a 4-year follow-up. Cephalalgia. 2004;24:850-858. – reference: Aronoff GM. Opioids in chronic pain management: Is there a significant risk of addiction? Curr Rev Pain. 2000;4:112-121. – reference: Pancheri P, Sirigatti S. MMPI-2 (Italian Version). Firenze: Organizzazioni Speciali; 1995. – reference: Grazzi L, Andrasik F, D'Amico D, et al. Behavioral and pharmacologic treatment of transformed migraine with analgesic overuse: Outcome at 3 years. Headache. 2002;59:1011-1114. – reference: Radat F, Creac'h C, Guegan-Massardier E, et al. Behavioral dependence in patients with medication overuse headache: A cross-sectional study in consulting patients using the DSM-IV criteria. Headache. 2008;48:1026-1036. – reference: Compton P, Darakjian J, Miotto K. Screening for addiction in patients with chronic pain and "problematic" substance use: Evaluation of a pilot assessment tool. J Pain Symptom Manage. 1998;16:355-363. – reference: Radat F, Sakh D, Lutz G, el Amrani M, Ferreri M, Bousser MG. Psychiatric comorbidity is related to headache induced by chronic substance use in migraineurs. Headache. 1999;39:477-480. – reference: Clements R, Heintz JM. Diagnostic accuracy and factor structure of the AAS and APS scales of the MMPI-2. J Pers Assess. 2002;79:564-582. – reference: Headache Classification Subcommittee of the International Headache Society. The International Classification of Headache Disorders-2nd edition. Cephalalgia. 2004;24(Suppl. 1):9-160. – reference: Mongini F, Ibertis F, Barbalonga E, Raviola F. MMPI-2 profiles in chronic daily headache and their relationship to anxiety levels and accompanying symptoms. Headache. 2000;40:466-472. – reference: Rossi P, Jensen R, Nappi G, Allena M, COMOESTAS Consortium. A narrative review on the management of medication overuse headache: The steep road from experience to evidence. J Headache Pain. 2009;10:407-417. – reference: Pascual J, Colás R, Castillo J. Epidemiology of chronic daily headache. Curr Pain Headache Rep. 2001;5:529-536. – reference: American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). International Version with ICD-10 codes. Washington, DC: American Psychiatric Association; 1994. – reference: Atasoy HT, Atasoy N, Unal AE, Emre U, Sumer M. Psychiatric comorbidity in medication overuse headache patients with pre-existing headache type of episodic tension-type headache. Eur J Pain. 2005;9:285-291. – reference: Weed NC, Butcher JN, McKenna T, Ben-Porath YS. New measures for assessing alcohol and drug abuse with the MMPI-2: The APS and AAS. J Pers Assess. 1992;58:389-404. – reference: Butcher JN, Dahlstrom WG, Graham JR, Tellegen A. MMPI-2. Minneapolis, MN: Minnesota University Press; 1989. – reference: Ferrari A, Leone S, Tacchi R, et al. The link between pain patient and analgesic medication is greater in migraine than in rheumatic disease patients. Cephalalgia. 2009;29:31-37. – reference: Mongini F, Rota E, Deregibus A, Mura F, Francia Germani A, Mongini T. A comparative analysis of personality profile and muscle tenderness between chronic migraine and chronic tension-type headache. Neurol Sci. 2005;26:203-207. – reference: Cloninger CR. The Temperament and Character Inventory - Revised. St. Louis, MO: Center for Psychobiology of Personality, Washington University; 1999. – reference: Weissman DE, Haddox JD. Opioid pseudoaddiction - an iatrogenic syndrome. Pain. 1989;36:363-366. – reference: Fumal A, Laureys S, Di Clemente L, et al. Orbitofrontal cortex involvement in chronic analgesic-overuse headache evolving from episodic migraine. Brain. 2006;129:543-550. – reference: Serretti A, Calati R, Giegling I, et al. 5-HT2A SNPs and the Temperament and Character Inventory. 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Background.— Medication‐overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of... Medication-overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of personality needs studies to explain the... (Headache 2011;51:1212-1227) Background.-- Medication-overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of... Background.- Medication-overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of personality needs studies to... |
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| SubjectTerms | Addicts Adult Age Biological and medical sciences Classification Data processing dependence Drug abuse Drug addiction Drug dependence Female Headache Headache Disorders, Secondary - complications Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Headaches Humans Inventories Male Medical research Medical sciences medication-overuse headache Middle Aged MMPI MMPI-2 Nervous system (semeiology, syndromes) Neurology Pain Personality Personality Disorders - diagnosis Personality Disorders - etiology Statistics Statistics, Nonparametric Stress, Psychological - diagnosis Stress, Psychological - etiology Substance-Related Disorders - complications Surveys and Questionnaires Vascular diseases and vascular malformations of the nervous system |
| Title | Differences in the Personality Profile of Medication-Overuse Headache Sufferers and Drug Addict Patients: A Comparative Study Using MMPI-2 |
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