Influenza-Associated Encephalitis/Encephalopathy with a Reversible Lesion in the Splenium of the Corpus Callosum: A Case Report and Literature Review
We report the cases of two patients with influenza-associated encephalitis/encephalopathy (IAEE) who presented with mild CNS manifestations and complete recovery within a few days. Initial MR imaging at days 4 and 5 revealed a lesion in the central portion of the splenium of the corpus callosum with...
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| Published in | American journal of neuroradiology : AJNR Vol. 25; no. 5; pp. 798 - 802 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
Oak Brook, IL
Am Soc Neuroradiology
01.05.2004
American Society of Neuroradiology |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0195-6108 1936-959X |
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| Abstract | We report the cases of two patients with influenza-associated encephalitis/encephalopathy (IAEE) who presented with mild CNS manifestations and complete recovery within a few days. Initial MR imaging at days 4 and 5 revealed a lesion in the central portion of the splenium of the corpus callosum with a reduced apparent diffusion coefficient (ADC) value, which completely resolved on follow-up studies at day 10. We postulate two possible mechanisms for decreased ADC; namely, intramyelinic edema and an inflammatory infiltrate. |
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| AbstractList | We report the cases of two patients with influenza-associated encephalitis/encephalopathy (IAEE) who presented with mild CNS manifestations and complete recovery within a few days. Initial MR imaging at days 4 and 5 revealed a lesion in the central portion of the splenium of the corpus callosum with a reduced apparent diffusion coefficient (ADC) value, which completely resolved on follow-up studies at day 10. We postulate two possible mechanisms for decreased ADC; namely, intramyelinic edema and an inflammatory infiltrate. We report the cases of two patients with influenza-associated encephalitis/encephalopathy (IAEE) who presented with mild CNS manifestations and complete recovery within a few days. Initial MR imaging at days 4 and 5 revealed a lesion in the central portion of the splenium of the corpus callosum with a reduced apparent diffusion coefficient (ADC) value, which completely resolved on follow-up studies at day 10. We postulate two possible mechanisms for decreased ADC; namely, intramyelinic edema and an inflammatory infiltrate.We report the cases of two patients with influenza-associated encephalitis/encephalopathy (IAEE) who presented with mild CNS manifestations and complete recovery within a few days. Initial MR imaging at days 4 and 5 revealed a lesion in the central portion of the splenium of the corpus callosum with a reduced apparent diffusion coefficient (ADC) value, which completely resolved on follow-up studies at day 10. We postulate two possible mechanisms for decreased ADC; namely, intramyelinic edema and an inflammatory infiltrate. |
| Author | Takanashi, Jun-ichi Yamaguchi, Ken-ichi Kohno, Yoichi Barkovich, A. James |
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| Keywords | Infection Case study Encephalitis Nervous system diseases Radiodiagnosis Viral disease Central nervous system disease Influenza A Corpus callosum Cerebral disorder |
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| SubjectTerms | Biological and medical sciences Brain Child Corpus Callosum Diffusion Magnetic Resonance Imaging Encephalitis, Viral - diagnosis Encephalitis, Viral - virology Female Humans Influenza, Human - diagnosis Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Nervous system Radiodiagnosis. Nmr imagery. Nmr spectrometry |
| Title | Influenza-Associated Encephalitis/Encephalopathy with a Reversible Lesion in the Splenium of the Corpus Callosum: A Case Report and Literature Review |
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