Variational Physiologically Informed Solution to Hemodynamic and Perfusion Response Estimation from ASL fMRI Data
Functional Arterial Spin Labeling (fASL) MRI can provide a quantitative measurement of cerebral blood flow. A joint detection-estimation (JDE) framework has been considered to extract task-related perfusion and hemodynamic responses not restricted to canonical response function shapes. In this work,...
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Published in | 2015 International Workshop on Pattern Recognition in NeuroImaging pp. 57 - 60 |
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Main Authors | , , |
Format | Conference Proceeding |
Language | English |
Published |
IEEE
01.06.2015
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Online Access | Get full text |
DOI | 10.1109/PRNI.2015.12 |
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Abstract | Functional Arterial Spin Labeling (fASL) MRI can provide a quantitative measurement of cerebral blood flow. A joint detection-estimation (JDE) framework has been considered to extract task-related perfusion and hemodynamic responses not restricted to canonical response function shapes. In this work, we provide a variational expectation-maximization (VEM) algorithm for hemodynamic and perfusion responses estimation. This approach provides a lower computational load compared to previous attempts, and facilitates the incorporation of prior knowledge and constraints in the estimation. Validation on simulated and real data sets has been performed. |
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AbstractList | Functional Arterial Spin Labeling (fASL) MRI can provide a quantitative measurement of cerebral blood flow. A joint detection-estimation (JDE) framework has been considered to extract task-related perfusion and hemodynamic responses not restricted to canonical response function shapes. In this work, we provide a variational expectation-maximization (VEM) algorithm for hemodynamic and perfusion responses estimation. This approach provides a lower computational load compared to previous attempts, and facilitates the incorporation of prior knowledge and constraints in the estimation. Validation on simulated and real data sets has been performed. |
Author | Ciuciu, Philippe Frau-Pascual, Aina Forbes, Florence |
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Snippet | Functional Arterial Spin Labeling (fASL) MRI can provide a quantitative measurement of cerebral blood flow. A joint detection-estimation (JDE) framework has... |
SourceID | ieee |
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StartPage | 57 |
SubjectTerms | ASL Estimation fMRI Hemodynamics Hidden Markov models HRF JDE Magnetic resonance imaging Physiology Shape Signal to noise ratio VEM |
Title | Variational Physiologically Informed Solution to Hemodynamic and Perfusion Response Estimation from ASL fMRI Data |
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