Histomorphometric Evaluation of the Effects of Mandibular Advancement Appliance and Low Level Laser Therapy con Diferentes Dosis en Cartilago Condilar y Hueso Subcondral en Ratas

The aim of this study was to evaluate the effects of mandibular advancement appliance and low level laser therapy (LLLT) with different doses on cellular hypertrophic changes in the mandibular condyle of rats. Forty-eight 8-week-old male Wistar albino rats weighing between 260 and 280 g were randoml...

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Published inInternational journal of morphology Vol. 38; no. 2; p. 252
Main Authors Oksayan, Ridvan, Sokucu, Oral, Ucuncu, Neslihan
Format Journal Article
LanguageSpanish
Published Universidad de La Frontera, Facultad de Medicina 01.06.2020
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ISSN0717-9367

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Abstract The aim of this study was to evaluate the effects of mandibular advancement appliance and low level laser therapy (LLLT) with different doses on cellular hypertrophic changes in the mandibular condyle of rats. Forty-eight 8-week-old male Wistar albino rats weighing between 260 and 280 g were randomly divided into four experimental and control groups. Group I was the control group; group II was the mandibular advancement appliance group; group III was the 8 J/cm (2) (0.25 W, 20 s) laser irradiation with mandibular advancement appliance group; and group IV was the 10 J/cm (2) (0.25 W, 25 s) laser irradiation with mandibular advancement appliance group. Mandibular condyle cartilage and subchondral bone changes with different LLLT dose and mandibular advancement appliance were evaluated by histomorphometrical analysis. Subchondral bone fraction results showed that there were no significant differences between groups (p<0.05). The statistically significant differences found between control group and experimental groups in anterior and posterior cartilage layers thickness (p<0.05) and (p<0.01). Posterior and anterior condylar cartilage layers of rats react differentially to LLLT and mandibular advancement application. Maximum changes in condylar cartilage layers were found in 8 J/cm (2) laser irradiation with mandibular appliance group. KEY WORDS: Low level laser therapy; Mandibular advancement; Rat; Histomorphometric.
AbstractList The aim of this study was to evaluate the effects of mandibular advancement appliance and low level laser therapy (LLLT) with different doses on cellular hypertrophic changes in the mandibular condyle of rats. Forty-eight 8-week-old male Wistar albino rats weighing between 260 and 280 g were randomly divided into four experimental and control groups. Group I was the control group; group II was the mandibular advancement appliance group; group III was the 8 J/cm (2) (0.25 W, 20 s) laser irradiation with mandibular advancement appliance group; and group IV was the 10 J/cm (2) (0.25 W, 25 s) laser irradiation with mandibular advancement appliance group. Mandibular condyle cartilage and subchondral bone changes with different LLLT dose and mandibular advancement appliance were evaluated by histomorphometrical analysis. Subchondral bone fraction results showed that there were no significant differences between groups (p<0.05). The statistically significant differences found between control group and experimental groups in anterior and posterior cartilage layers thickness (p<0.05) and (p<0.01). Posterior and anterior condylar cartilage layers of rats react differentially to LLLT and mandibular advancement application. Maximum changes in condylar cartilage layers were found in 8 J/cm (2) laser irradiation with mandibular appliance group. KEY WORDS: Low level laser therapy; Mandibular advancement; Rat; Histomorphometric.
The aim of this study was to evaluate the effects of mandibular advancement appliance and low level laser therapy (LLLT) with different doses on cellular hypertrophic changes in the mandibular condyle of rats. Forty-eight 8-week-old male Wistar albino rats weighing between 260 and 280 g were randomly divided into four experimental and control groups. Group I was the control group; group II was the mandibular advancement appliance group; group III was the 8 J/cm (2) (0.25 W, 20 s) laser irradiation with mandibular advancement appliance group; and group IV was the 10 J/cm (2) (0.25 W, 25 s) laser irradiation with mandibular advancement appliance group. Mandibular condyle cartilage and subchondral bone changes with different LLLT dose and mandibular advancement appliance were evaluated by histomorphometrical analysis. Subchondral bone fraction results showed that there were no significant differences between groups (p<0.05). The statistically significant differences found between control group and experimental groups in anterior and posterior cartilage layers thickness (p<0.05) and (p<0.01). Posterior and anterior condylar cartilage layers of rats react differentially to LLLT and mandibular advancement application. Maximum changes in condylar cartilage layers were found in 8 J/cm (2) laser irradiation with mandibular appliance group.
Audience Professional
Author Sokucu, Oral
Oksayan, Ridvan
Ucuncu, Neslihan
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SubjectTerms Analysis
Appliances
Laser surgery
Medical lasers
Title Histomorphometric Evaluation of the Effects of Mandibular Advancement Appliance and Low Level Laser Therapy con Diferentes Dosis en Cartilago Condilar y Hueso Subcondral en Ratas
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