Resistance of fibrogenic responses to glucocorticoid and 2-methoxyestradiol in bleomycin-induced lung fibrosis in mice - LANGENBACH, Shenna Y; WHEATON, Ben J; FERNANDES, Darren J; JONES, Catherine; SUTHERLAND, Tara E; WRAITH, Bronwyn C; HARRIS, Trudi; SCHULIGA, Michael J; MCLEAN, Catriona; STEWART, Alastair G (Canadian journal of physiology and pharmacology, 2007)
Keywords: Airway Resistance - drug effects; Animal experimentation; Animals; Biological and medical sciences; Bleomycin - toxicity; Body Weight - drug effects; Bronchoalveolar Lavage Fluid - chemistry; Bronchoalveolar Lavage Fluid - cytology; Cell Adhesion Molecules - genetics; Corticosteroids; Cytokines - genetics; Drug Resistance; Estradiol - analogs & derivatives; Estradiol - pharmacology; Estradiol - therapeutic use; Fibrosis; Fundamental and applied biological sciences. Psychology; Gene Expression - drug effects; Glucocorticoids - pharmacology; Glucocorticoids - therapeutic use; Hydroxyproline - analysis; Lung - drug effects; Lung - metabolism; Lung - physiopathology; Lung Compliance - drug effects; Lungs; Matrix Metalloproteinases - genetics; Methylprednisolone; Methylprednisolone - pharmacology; Methylprednisolone - therapeutic use; Mice; Mice, Inbred C57BL; Organ Size - drug effects; Physiological aspects; Pulmonary Alveoli - drug effects; Pulmonary Alveoli - metabolism; Pulmonary Alveoli - pathology; Pulmonary Emphysema - chemically induced; Pulmonary Emphysema - drug therapy; Pulmonary Emphysema - metabolism; Pulmonary Fibrosis - chemically induced; Pulmonary Fibrosis - drug therapy; Pulmonary Fibrosis - metabolism; Reverse Transcriptase Polymerase Chain Reaction; Tissue Inhibitor of Metalloproteinases - genetics; Tubulin Modulators - pharmacology; Tubulin Modulators - therapeutic use; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Australia; Corticosteroid; Lung disease; Peptides; Respiratory disease; Steroid hormone; Hydroxyproline; Rodentia; Methylprednisolone; Glucocorticoid; Asthma; Vertebrata; Mammalia; Bleomycin; Pulmonary fibrosis; Mouse; Glycopeptide; Bronchus disease; Obstructive pulmonary disease