CaII Binding Regulates and Dominates the Reactivity of a Transition-Metal-Ion-Dependent Diesterase from Mycobacterium tuberculosis - Pedroso, Marcelo M.; Larrabee, James A.; Ely, Fernanda; Gwee, Shuhui E.; Mitić, Nataša; Ollis, David L.; Gahan, Lawrence R.; Schenk, Gerhard (Chemistry : a European journal, 2016)
Keywords: Aerogenes; Binding; Binding sites; calcium; Chemistry; Control; coordination spheres; Cyclic nucleotides; dinuclear metallohydrolases; Enzymatic activity; enzyme catalysis; Heat measurement; Hydrolysis; Intracellular; Intracellular levels; Ions; Metal ions; Metals; Nucleotides; organophosphate pesticides; Signal transduction; Spectroscopy; Substrates; Tuberculosis