Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase γ replication fidelity - Pursell, Zachary F; McDonald, J. Tyson; Mathews, Christopher K; Kunkel, Thomas A (Nucleic acids research, 2008)
Keywords: adenine; Animals; Deoxyguanine Nucleotides - metabolism; Deoxyribonucleotides - metabolism; DNA Polymerase gamma; DNA Replication; DNA, Mitochondrial - biosynthesis; DNA, Mitochondrial - chemistry; DNA-directed DNA polymerase; DNA-Directed DNA Polymerase - metabolism; electron transport chain; humans; Male; Mice; mitochondria; Mitochondria - metabolism; Mitochondria, Heart - genetics; Mitochondria, Heart - metabolism; mitochondrial genome; Molecular Biology; mutagenesis; nucleic acids; oxidation; Rats; Rats, Wistar; reactive oxygen species; tissues